Filipa Diana da Silva Mendes (4511-2E7B-2A15)

Curriculum Vitae

Filipa Diana da Silva Mendes

Filipa Diana da Silva Mendes completed a bachelor's degree in Biology-Geology in 2014 (with a grade of 14 out of 20) and a master's in Molecular Genetics in 2017 (with a grade of 17 out of 20), both at the University of Minho. Currently she is a PhD student of Doctoral Program in Molecular and Environmental Biology (FCT grant ref: SFRH/BD/147574/2019). Her PhD project intends to generate ecotoxicity data for risk assessment for substances of interest based on their common use in vineyards and develop and validate novel easy-to use yeast-based biosensor for water monitoring programs being developed in accordance with the project FunG-Eye: A functional approach to unravel the interaction between fungicide pollution and fungi-mediated ecosystem processes in which she is a team member. In 2018, she received an award from the national contest FoodValorization and integrated the research project "Recovery of acidic wines through reduction of their volatile acidity by the yeast Zygosaccharomyces bailli" as a co-promoter. She also collaborated with another ongoing project addressing the role of metabolism in the response to the chemotherapeutic agent cisplatin. This work resulted in a co-first authorship scientific article, in three poster presentations in national congresses and in an oral presentation in a seminar organized by the Biology Department. She also attended different training courses and workshops, scientific meetings and participated and organized several multiple science dissemination/outreach programs. She also has taken on the co-supervision of Masters and undergraduate students.

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Identification

Personal identification

Full name: Filipa Diana da Silva Mendes

Citation names

Mendes, Filipa

Author identifiers

Ciência ID: 4511-2E7B-2A15
ORCID iD: 0000-0003-2659-4591

Email addresses

filipamendes06@gmail.com (Professional)

Telephones

Mobile phone

918306513 (Personal)

Addresses

Rua S. José nº1598, 4810-707, Abação, Guimarães, Portugal (Personal)

Knowledge fields

Natural sciences
Natural sciences - Biological Sciences
Natural sciences - Biological Sciences - Biology
Natural sciences - Biological Sciences - Cell Biology
Natural sciences - Biological Sciences - Molecular Biology
Natural sciences - Biological Sciences - Biochemistry

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2019 - 2023 Ongoing	Biologia Molecular e Ambiental (Doutoramento) Universidade do Minho, Portugal
2020/07 - 2020/07 Concluded	Protein Degradation and Trafficking in Health and Disease (Outros) Universidade do Minho, Portugal	19
2020/05 - 2020/06 Concluded	Metabolic Engineering (Outros) Universidade do Minho, Portugal	18
2014/10 - 2017/03 Concluded	Molecular Genetics (Mestrado) Major in cellular and functional biology, molecular genetics and biotechnology Universidade do Minho Escola de Ciências, Portugal "“Bax activation by PKCe modulation: An attractive target to eliminate cancer cells” " (THESIS/DISSERTATION)	17
2015/06 - 2015/07 Concluded	Mammalian and yeast cells as models in programmend cell death (Outros) Universidade do Minho Escola de Ciências, Portugal	18
2015/06 - 2015/06 Concluded	Cancer therapy: from basic research to clinic (Outros) Universidade do Minho Escola de Ciências, Portugal Universidade do Minho Escola de Medicina, Portugal	19
2015/04 - 2015/04 Concluded	Biopolymers Based on Renewable Resources: from Synthesis to Applications (Outros) Universidade do Minho Escola de Ciências, Portugal	16
2011/09/19 - 2014/08/25 Concluded	Biology-Geology (Licenciatura) Major in biology-geology gives scientific preparation in the different areas. Universidade do Minho Escola de Ciências, Portugal	14

Affiliation

Science

	Category Host institution	Employer
2023/03/01 - 2023/05/07	Visiting Researcher (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	Université de Bordeaux - Pessac Campus, France
2023/01/05 - 2023/02/05	Visiting Researcher (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	Weizmann Institute of Science, Israel

Projects

Grant

	Designation	Funders
2019/10/01 - Current	Novel tools and data for the detection and assessment of ecological risks of fungicides SFRH/BD/147574/2019 PhD Student Fellow	Fundação para a Ciência e a Tecnologia Ongoing
2019/05/02 - 2019/09/30	FunG-Eye: A functional approach to unravel the interaction between fungicide pollution and fungi-mediated ecosystem processes POCI-01-0145-FEDER-029505 Research Technician Fellow Universidade do Minho, Portugal	Ongoing

Contract

	Designation	Funders
2018/06/01 - 2021/05/31	Fung-Eye: Uma abordagem funcional para compreender a interação entre a poluição por fungicidas e os processos do ecossistema mediados por fungos PTDC/CTA-AMB/29505/2017 Universidade de Aveiro, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018/07 - 2019/04	Recovery of acidic wines through reduction of their volatile acidity by the yeast Zygosaccharomyces bailli NORTE-01-0246-FEDER-000043 Researcher Universidade do Minho, Portugal	Ongoing

Other

	Designation	Funders
2022/01/01 - 2023/12/31	Wine-Tuning: Novel strains and methods to overcome emergent challenges in wine production EXPL/BAA-AGR/1096/2021 Researcher Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2020/01/01 - 2021/05/31	FunG-Eye: a functional approach to unravel the interaction between fungicide pollution and fungi-mediated ecosystem processes POCI-01-0145-FEDER-029505 Researcher Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/09 - 2019/04	The effect of carbon source in the sensitivity to the anti-cancer agent cisplatin Internal project Researcher Universidade do Minho, Portugal	Concluded
2013/04/01 - 2017/03/31	Phosphoregulation of Bax-dependent cell death info:eu-repo/grantAgreement/FCT/3599-PPCDT/125757/PT Researcher Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Conference poster	Joana P. Guedes; Machado Beatriz; Mendes, Filipa; Manon Stéphen; CHAVES, SUSANA; Côrte-Real, Manuela. "NatB regulates Bax-induced cell death in a heterologous expression model system". Paper presented in I CBMA Open Day & II PhD\|Bio Symposium, 2024. Mendes, Filipa; Fonseca Carolina; Joana P. Guedes; Sousa, Maria João; CHAVES, SUSANA; Côrte-Real, Manuela. "Zygosaccharomyces parabailii can reduce volatile acidity of acidic wines". Paper presented in I CBMA Open Day & II PhD\|Bio Symposium, 2024. Amaral, Leslie; Martins Márcia; Mendes, Filipa; Corte-Real M; Rego, António; Outeiro, Tiago; CHAVES, SUSANA. "A versatile yeast model to screen for pesticides as risk factors for synucleinopathies". Paper presented in I CBMA Open Day & II PhD\|Bio Symposium, 2024. Mendes, Filipa; Cátia Santos-Pereira; Vieira, Tatiana F.; Martins-Pinto Mélanie; Castro, Bruno B.; Sousa, Sérgio F.; Sousa, Maria João; Devin Anne; CHAVES, SUSANA. "The cymoxanil fungicide impairs Saccharomyces cerevisiae respiration via complex IV inhibition". Paper presented in I CBMA Open Day & II PhD\|Bio Symposium, 2024. Mendes, Filipa; Cátia Santos-Pereira; Vieira, Tatiana F.; Martins-Pinto Mélanie; Castro, Bruno B.; Sousa, Sérgio F.; Sousa, Maria João; Chaves Susana R.. "Cymoxanil inhibits respiration through inhibition of mitochondrial complex IV". Paper presented in 31st International Conference on Yeast Genetics and Molecular Biology, 2023. Joana P. Guedes; Cardoso Tiago; Mendes, Filipa; Fernandes, Ticiana; Ricardo Franco-Duarte; Baleiras-Couto Margarida; Duarte Filomena; et al. "Exploring wine yeast natural biodiversity to select strains with enological traits adapted to climate change". Paper presented in 31st International Conference on Yeast Genetics and Molecular Biology, 2023. Mendes, Filipa; Joana P. Guedes; Cardoso Tiago; Sousa, Maria João; Côrte-Real, Manuela; CHAVES, SUSANA. "Bio-reduction of wine volatile acidity using yeast cells". Paper presented in 31st International Conference on Yeast Genetics and Molecular Biology, 2023. Mendes, Filipa; Joana P. Guedes; Baleiras-Couto Margarida; Duarte Filomena; Sousa, Maria João; CHAVES, SUSANA; Côrte-Real, Manuela. "Recovery of acidic wines through bio-reduction of their volatile acidity using yeast cells". Paper presented in MicroSummit 2022, 2022. Mendes, Filipa; Eduarda Miranda; Amaral, Leslie; Castro, Bruno B.; Sousa, Maria João; Chaves Susana R. "A yeast-based biosensor to monitor tebuconazole in environmental samples". Paper presented in The Biochemistry Global Summit, 2022. Cardoso Tiago; Mendes, Filipa; Rego António; Sousa, Maria João; Chaves Susana R. "Exploring the mechanism of action of cymoxanil". Paper presented in Microbiotec’21, 2021. Mendes, Filipa; Eduarda Miranda; Amaral, Leslie; Castro, Bruno B.; Sousa, Maria João; Chaves Susana R. "Novel yeast-based biosensor for environmental monitoring". Paper presented in 15th International Congress on Yeasts meets the 30th International Conference on Yeast Genetics and Molecular Biology, 2021. Mendes, Filipa; Côrte-Real, Manuela; CHAVES, SUSANA. "Recovery of acidic wines through reduction of their volatile acidity by the yeast Zygosaccharomyces bailli". Paper presented in V Symposium of the PhD Programme on Molecular and Environmental Biology, 2019. Amaral, Leslie; Mendes, Filipa; Côrte-Real, Manuela; Sousa, MJ; CHAVES, SUSANA. "Carbon source affects sensitivity to the anti-cancer agent cisplatin in Saccharomyces cerevisiae". Paper presented in V Symposium of the PhD Programme on Molecular and Environmental Biology, 2019. Mendes, FS; Amaral, Leslie; Côrte-Real, M; Sousa, MJ; FC1A-F4E3-6141. "How carbon source affects the sensitivity to the anti-cancer agent cisplatin". Paper presented in I Jornadas da Ciência: Concentra o Conhecimento, 2019. Mendes, FS; Amaral, L; Martins, V; Côrte-Real, M; Sousa, MJ; FC1A-F4E3-6141. "The effect of carbon source in the sensitivity to the anti-cancer agent cisplatin". Paper presented in IV Symposium of the PhD Programme on Molecular and Environmental Biology, 2018.
Journal article	Filipa Mendes; Eduarda Miranda; Leslie Amaral; Carla Carvalho; Bruno B. Castro; Maria João Sousa; Susana Chaves. "Novel yeast-based biosensor for environmental monitoring of tebuconazole". Applied Microbiology and Biotechnology (2024): http://dx.doi.org/10.1007/s00253-023-12944-z. 10.1007/s00253-023-12944-z Filipa Mendes; Cátia Santos-Pereira; Tatiana F. Vieira; Mélanie Martins Pinto; Bruno B. Castro; Sérgio F. Sousa; Maria João Sousa; Anne Devin; Susana Chaves. "The fungicide cymoxanil impairs respiration in Saccharomyces cerevisiae via cytochrome c oxidase inhibition". FEBS Letters (2024): http://dx.doi.org/10.1002/1873-3468.14907. 10.1002/1873-3468.14907 Amaral, Leslie; Mendes, Filipa; Côrte-Real, Manuela; Sousa, Maria João; Chaves, Susana Rodrigues. "Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-8. http://dx.doi.org/10.1155/2020/4971525. 10.1155/2020/4971525 Rego, António; Mendes, Filipa; Costa, Vítor; Chaves, Susana Rodrigues; Côrte-Real, Manuela. "Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-14. http://dx.doi.org/10.1155/2020/7095078. Published • 10.1155/2020/7095078
Thesis / Dissertation	Chaves, Susana Alexandra Rodrigues; Alves, Sara Cristina Sequeira; Mendes, Filipa Diana da Silva. "Bax activation by PKC modulation: an attractive target to eliminate cancer cells". Master, Universidade do Minho Escola de Ciências, 2017. http://hdl.handle.net/1822/45647.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/12/21	Bio-reduction of wine volatile acidity using yeast cells	Winetunning Final Workshop (Braga, Portugal)
2023/02/08	Yeast a novel tool for the detection and assessment of ecological risks of fungicides”.	I Symposium PhD Bio (Braga, Portugal)
2021/12/06	Bio-deteção de fungicidas azólicos	At the workshop “Uma abordagem funcional para compreender a interação entre a poluição por fungicidas e os processos do ecossistema mediados por fungos”, promoted by FunG-Eye project Universidade do Minho (Braga, Portugal)
2021/03/31	Bio-Detection of fungicides: An alternative to traditional methods”	At the webinar "Bio-Deteção e Efeitos ecológicos de fungicidas em sistemas aquáticos: modelos biológicos e resultados do projeto FunG-Eye"¿, promoted by FunG-Eye project Universidade do Minho (Braga, Portugal)
2019/03/20	Carbon source affects the sensitivity to the anti-cancer agent cisplatin	Biology Department Seminar Universidade do Minho, Escola de Ciências, Departamento de Biologia (Braga, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2020/04 - 2020/07	A yeast biosensor to detect azole contaminants Co-supervisor	Bioquímica (Degree) Universidade do Minho, Portugal
2019/03 - 2019/07	A yeast biosensor to detect azole contaminants Co-supervisor	Bioquímica (Degree) Universidade do Minho, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2019/01/04 - Current	Ongoing participation in Pint of Science, which is an international event aiming to promote science for general society in bars. I am an event manager of the theme "Com Pés e Cabeça", which covers topics from medicine to molecular and cellular biology. (2019/05/20 - 2019/05/22) Meeting (Member of the Organising Committee)
2019/03/14 - 2019/03/14	Co-organized the workshop "Fluorescent Molecular Probes", in the scope of "Jornadas da Ciência: Concentra o Conhecimento. In this workshop, we used different fluorescent molecular probes and the fluorescence microscope to visualize several cellular compartments using cell lines and yeast cells as models. During the workshop, we discussed the various types of probes and their characteristics, as well as practical applications. (2019/03/14 - 2019/03/14) Workshop (Co-organisor)	Universidade do Minho, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2018/12/04 - Current	Volunteer in the in initiative "Investigadores voltam à escola" organized by the School of Sciences, University of Minho. The goal of this project is that researchers from the School of Sciences interact with high school students and explain their research, such as day-to-day lab work, their academic background, personal and professional journey, and passion for science. Other	Investigadores Voltam à Escola Universidade do Minho Escola de Ciências, Portugal
2019/03/15 - 2020/09	Volunteer in the initiative "Programas de visitas à Escola de Ciências" organized by the School of Sciences, University of Minho. The aim of this project is to show the teaching and research opportunities of the School of Sciences, University of Minho. This project offers several activities that include guided visits to the facilities and laboratories, participation in hands-on activities, experimental demonstrations, lectures, among others. So far, I co-organized a hands-on experiment using fluorescence microscopy. Other	Programas de visitas à Escola de Ciências Universidade do Minho Escola de Ciências, Portugal
2019/03/11 - 2019/03/15	Attended the conference "1st Journeys of Science of University of Minho". This event aimed to share knowledge in the area of biological and environmental sciences. Several speakers gave seminars on both fundamental and applied science. Congress	I Jornadas da Ciência: [Ciência] - Concentra o Conhecimento Universidade do Minho, Portugal
2019/03/13 - 2019/03/13	Attended the workshop "Poluição vs Doença: a verdade escondida sobre os impactos ecológicos dos pesticidas ". This workshop introduced the use of pesticides in agriculture and the pollution vs. disease problem. It was also an opportunity to get acquainted with a biological model that provides innovative knowledge on the ecological impacts of these agrochemicals on non-target fungi, a subject of the proposed thesis. Workshop	I Jornadas da Ciência: [Ciência] - Concentra o Conhecimento Universidade do Minho, Portugal
2019/03/11 - 2019/03/11	Attended the workshop "Contaminantes emergentes - O presente e o futuro a nível global". This workshop introduced the use of emerging chemical contaminants on a global and constituent scale, currently a focus of great concern. Workshop	I Jornadas da Ciência: [Ciência] - Concentra o Conhecimento Universidade do Minho, Portugal
2018/10/15 - 2018/10/17	Attended the event "INL SUMMIT\| Nanotecnology: An enabler for the new economy" where visionaries from around the world came together to share, interact and collaborate with scientists, business experts, entrepreneurs, artists, changemakers and innovators. Conference	“INL SUMMIT\| Nanotecnology: An enabler for the new economy” International Iberian Nanotechnology Laboratory, Portugal
2018/10 - 2018/10	Attended the event IV Symposium of the PhD Programme on Molecular and Environmental Biology. In this symposium there is a presentation of the work developed in the CBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers. Symposium	“IV Symposium of the PhD Programme on Molecular and Environmental Biology” Universidade do Minho Escola de Ciências, Portugal
2018/09/28 - 2018/09/28	Volunteered in the event European researchers night, organized by the School of Sciences, University of Minho. Exhibition	European researchers’ night Universidade do Minho Escola de Ciências, Portugal
2015/11 - 2015/11	Attended the event III Symposium of the PhD Programme on Molecular and Environmental Biology. This symposium included presentations of work developed atCBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers. Symposium	III Symposium of the PhD Programme on Molecular and Environmental Biology¿ Universidade do Minho Escola de Ciências, Portugal
2015/09/29 - 2015/10/03	Attended the "11th International meeting on yeast apoptosis (IMYA 2015) conference, which brought together researchers who explore yeast as a preferred cellular model for applied research with an impact on biomedicine and biotechnology, in order to develop new therapeutic strategies in the field of apoptosis, programmed cell death, aging and in stress response mechanisms. Congress	"11th International meeting on yeast apoptosis (IMYA 2015)” Universidade do Minho Escola de Ciências, Portugal Universidade do Minho Escola de Medicina, Portugal
2014/11 - 2014/11	Attended the event II Symposium of the PhD Programme on Molecular and Environmental Biology. In this symposium, the work developed in the CBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers, were presented. Symposium	II Symposium of the PhD Programme on Molecular and Environmental Biology¿ Universidade do Minho Escola de Ciências, Portugal
2014/09/27 - 2014/09/27	Volunteered in the event European researchers night, organized by the School of Sciences, University of Minho. Exhibition	European researchers night Universidade do Minho Escola de Ciências, Portugal
2014 - 2014	Attended the event "Palestra de Ciências Forenses" organized by NEBUP- Núcleo de estudantes de biologia. Seminar	Palestra de Ciências Forenses Universidade do Porto, Portugal

Committee member

	Activity description Role	Institution / Organization
2021 - Current	Sub-coordinator of the PhD Students' Group of the Centre of Molecular and Environmental Biology Coordinator	Universidade do Minho, Portugal
2020 - 2021	Secretary of the PhD Students' Group of the Centre of Molecular and Environmental Biology Member	Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Mentoring / Tutoring

	Topic	Student name
2021/10/01 - Current	Novel yeast-based biosensors for drug discovery	Mariana Mota Gomes
2020/10/01 - 2021/12/31	Toxicogenomics - based testes for hazard assessement	Tiago André Vidal Cardoso
2020/10/01 - 2021/12/31	Novel yeast-based biosensor for environmental monitoring	Eduarda Maria Oliveira Miranda

Distinctions

Award

2023	Early career investigator fellowship to attendance in 31st International Conference on Yeast Genetics and Molecular Biology, 20-25 August, Florence, Italy Federation Of European Microbiological Societies, Netherlands
2018	Concurso FoodValorization NewFood Project: Universidade do Minho, Universidade do Porto, Universidade de Trás os Montes e Alto Douro, Universidade Católica, Portugal