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Filipa Diana da Silva Mendes completed a bachelor's degree in Biology-Geology in 2014 (with a grade of 14 out of 20) and a master's in Molecular Genetics in 2017 (with a grade of 17 out of 20), both at the University of Minho. Currently she is a PhD student of Doctoral Program in Molecular and Environmental Biology (FCT grant ref: SFRH/BD/147574/2019). Her PhD project intends to generate ecotoxicity data for risk assessment for substances of interest based on their common use in vineyards and develop and validate novel easy-to use yeast-based biosensor for water monitoring programs being developed in accordance with the project FunG-Eye: A functional approach to unravel the interaction between fungicide pollution and fungi-mediated ecosystem processes in which she is a team member. In 2018, she received an award from the national contest FoodValorization and integrated the research project "Recovery of acidic wines through reduction of their volatile acidity by the yeast Zygosaccharomyces bailli" as a co-promoter. She also collaborated with another ongoing project addressing the role of metabolism in the response to the chemotherapeutic agent cisplatin. This work resulted in a co-first authorship scientific article, in three poster presentations in national congresses and in an oral presentation in a seminar organized by the Biology Department. She also attended different training courses and workshops, scientific meetings and participated and organized several multiple science dissemination/outreach programs. She also has taken on the co-supervision of Masters and undergraduate students.
Identificação

Identificação pessoal

Nome completo
Filipa Diana da Silva Mendes

Nomes de citação

  • Mendes, Filipa

Identificadores de autor

Ciência ID
4511-2E7B-2A15
ORCID iD
0000-0003-2659-4591

Endereços de correio eletrónico

  • filipamendes06@gmail.com (Profissional)

Telefones

Telemóvel
  • 918306513 (Pessoal)

Moradas

  • Rua S. José nº1598, 4810-707, Abação, Guimarães, Portugal (Pessoal)

Domínios de atuação

  • Ciências Naturais
  • Ciências Naturais - Ciências Biológicas
  • Ciências Naturais - Ciências Biológicas - Biologia
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2019 - 2023
Em curso
Biologia Molecular e Ambiental (Doutoramento)
Universidade do Minho, Portugal
2020/07 - 2020/07
Concluído
Protein Degradation and Trafficking in Health and Disease (Outros)
Universidade do Minho, Portugal
19
2020/05 - 2020/06
Concluído
Metabolic Engineering (Outros)
Universidade do Minho, Portugal
18
2014/10 - 2017/03
Concluído
Molecular Genetics (Mestrado)
Especialização em cellular and functional biology, molecular genetics and biotechnology
Universidade do Minho Escola de Ciências, Portugal
"“Bax activation by PKCe modulation: An attractive target to eliminate cancer cells” " (TESE/DISSERTAÇÃO)
17
2015/06 - 2015/07
Concluído
Mammalian and yeast cells as models in programmend cell death (Outros)
Universidade do Minho Escola de Ciências, Portugal
18
2015/06 - 2015/06
Concluído
Cancer therapy: from basic research to clinic (Outros)
Universidade do Minho Escola de Ciências, Portugal

Universidade do Minho Escola de Medicina, Portugal
19
2015/04 - 2015/04
Concluído
Biopolymers Based on Renewable Resources: from Synthesis to Applications (Outros)
Universidade do Minho Escola de Ciências, Portugal
16
2011/09/19 - 2014/08/25
Concluído
Biology-Geology (Licenciatura)
Especialização em biology-geology gives scientific preparation in the different areas.
Universidade do Minho Escola de Ciências, Portugal
14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2023/03/01 - 2023/05/07 Investigador visitante (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Université de Bordeaux - Pessac Campus, França
2023/01/05 - 2023/02/05 Investigador visitante (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Weizmann Institute of Science, Israel
Projetos

Bolsa

Designação Financiadores
2019/10/01 - Atual Novel tools and data for the detection and assessment of ecological risks of fungicides
SFRH/BD/147574/2019
Bolseiro de Doutoramento
Fundação para a Ciência e a Tecnologia
Em curso
2019/05/02 - 2019/09/30 FunG-Eye: A functional approach to unravel the interaction between fungicide pollution and fungi-mediated ecosystem processes
POCI-01-0145-FEDER-029505
Bolseiro de Técnico de Investigação
Universidade do Minho, Portugal
Em curso

Projeto

Designação Financiadores
2018/06/01 - 2021/05/31 Fung-Eye: Uma abordagem funcional para compreender a interação entre a poluição por fungicidas e os processos do ecossistema mediados por fungos
PTDC/CTA-AMB/29505/2017
Universidade de Aveiro, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/07 - 2019/04 Recovery of acidic wines through reduction of their volatile acidity by the yeast Zygosaccharomyces bailli
NORTE-01-0246-FEDER-000043
Investigador
Universidade do Minho, Portugal
Em curso

Outro

Designação Financiadores
2022/01/01 - 2023/12/31 Wine-Tuning: Novel strains and methods to overcome emergent challenges in wine production
EXPL/BAA-AGR/1096/2021
Investigador
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020/01/01 - 2021/05/31 FunG-Eye: a functional approach to unravel the interaction between fungicide pollution and fungi-mediated ecosystem processes
POCI-01-0145-FEDER-029505
Investigador
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/09 - 2019/04 The effect of carbon source in the sensitivity to the anti-cancer agent cisplatin
Internal project
Investigador
Universidade do Minho, Portugal
Concluído
2013/04/01 - 2017/03/31 Phosphoregulation of Bax-dependent cell death
Investigador
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Filipa Mendes; Eduarda Miranda; Leslie Amaral; Carla Carvalho; Bruno B. Castro; Maria João Sousa; Susana Chaves. "Novel yeast-based biosensor for environmental monitoring of tebuconazole". Applied Microbiology and Biotechnology (2024): http://dx.doi.org/10.1007/s00253-023-12944-z.
    10.1007/s00253-023-12944-z
  2. Filipa Mendes; Cátia Santos-Pereira; Tatiana F. Vieira; Mélanie Martins Pinto; Bruno B. Castro; Sérgio F. Sousa; Maria João Sousa; Anne Devin; Susana Chaves. "The fungicide cymoxanil impairs respiration in Saccharomyces cerevisiae via cytochrome c oxidase inhibition". FEBS Letters (2024): http://dx.doi.org/10.1002/1873-3468.14907.
    10.1002/1873-3468.14907
  3. Amaral, Leslie; Mendes, Filipa; Côrte-Real, Manuela; Sousa, Maria João; Chaves, Susana Rodrigues. "Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-8. http://dx.doi.org/10.1155/2020/4971525.
    10.1155/2020/4971525
  4. Rego, António; Mendes, Filipa; Costa, Vítor; Chaves, Susana Rodrigues; Côrte-Real, Manuela. "Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-14. http://dx.doi.org/10.1155/2020/7095078.
    Publicado • 10.1155/2020/7095078
Poster em conferência
  1. Joana P. Guedes; Machado Beatriz; Mendes, Filipa; Manon Stéphen; CHAVES, SUSANA; Côrte-Real, Manuela. "NatB regulates Bax-induced cell death in a heterologous expression model system". Trabalho apresentado em I CBMA Open Day & II PhD|Bio Symposium, 2024.
  2. Mendes, Filipa; Fonseca Carolina; Joana P. Guedes; Sousa, Maria João; CHAVES, SUSANA; Côrte-Real, Manuela. "Zygosaccharomyces parabailii can reduce volatile acidity of acidic wines". Trabalho apresentado em I CBMA Open Day & II PhD|Bio Symposium, 2024.
  3. Amaral, Leslie; Martins Márcia; Mendes, Filipa; Corte-Real M; Rego, António; Outeiro, Tiago; CHAVES, SUSANA. "A versatile yeast model to screen for pesticides as risk factors for synucleinopathies". Trabalho apresentado em I CBMA Open Day & II PhD|Bio Symposium, 2024.
  4. Mendes, Filipa; Cátia Santos-Pereira; Vieira, Tatiana F.; Martins-Pinto Mélanie; Castro, Bruno B.; Sousa, Sérgio F.; Sousa, Maria João; Devin Anne; CHAVES, SUSANA. "The cymoxanil fungicide impairs Saccharomyces cerevisiae respiration via complex IV inhibition". Trabalho apresentado em I CBMA Open Day & II PhD|Bio Symposium, 2024.
  5. Mendes, Filipa; Cátia Santos-Pereira; Vieira, Tatiana F.; Martins-Pinto Mélanie; Castro, Bruno B.; Sousa, Sérgio F.; Sousa, Maria João; Chaves Susana R.. "Cymoxanil inhibits respiration through inhibition of mitochondrial complex IV". Trabalho apresentado em 31st International Conference on Yeast Genetics and Molecular Biology, 2023.
  6. Joana P. Guedes; Cardoso Tiago; Mendes, Filipa; Fernandes, Ticiana; Ricardo Franco-Duarte; Baleiras-Couto Margarida; Duarte Filomena; et al. "Exploring wine yeast natural biodiversity to select strains with enological traits adapted to climate change". Trabalho apresentado em 31st International Conference on Yeast Genetics and Molecular Biology, 2023.
  7. Mendes, Filipa; Joana P. Guedes; Cardoso Tiago; Sousa, Maria João; Côrte-Real, Manuela; CHAVES, SUSANA. "Bio-reduction of wine volatile acidity using yeast cells". Trabalho apresentado em 31st International Conference on Yeast Genetics and Molecular Biology, 2023.
  8. Mendes, Filipa; Joana P. Guedes; Baleiras-Couto Margarida; Duarte Filomena; Sousa, Maria João; CHAVES, SUSANA; Côrte-Real, Manuela. "Recovery of acidic wines through bio-reduction of their volatile acidity using yeast cells". Trabalho apresentado em MicroSummit 2022, 2022.
  9. Mendes, Filipa; Eduarda Miranda; Amaral, Leslie; Castro, Bruno B.; Sousa, Maria João; Chaves Susana R. "A yeast-based biosensor to monitor tebuconazole in environmental samples". Trabalho apresentado em The Biochemistry Global Summit, 2022.
  10. Cardoso Tiago; Mendes, Filipa; Rego António; Sousa, Maria João; Chaves Susana R. "Exploring the mechanism of action of cymoxanil". Trabalho apresentado em Microbiotec’21, 2021.
  11. Mendes, Filipa; Eduarda Miranda; Amaral, Leslie; Castro, Bruno B.; Sousa, Maria João; Chaves Susana R. "Novel yeast-based biosensor for environmental monitoring". Trabalho apresentado em 15th International Congress on Yeasts meets the 30th International Conference on Yeast Genetics and Molecular Biology, 2021.
  12. Mendes, Filipa; Côrte-Real, Manuela; CHAVES, SUSANA. "Recovery of acidic wines through reduction of their volatile acidity by the yeast Zygosaccharomyces bailli". Trabalho apresentado em V Symposium of the PhD Programme on Molecular and Environmental Biology, 2019.
  13. Amaral, Leslie; Mendes, Filipa; Côrte-Real, Manuela; Sousa, MJ; CHAVES, SUSANA. "Carbon source affects sensitivity to the anti-cancer agent cisplatin in Saccharomyces cerevisiae". Trabalho apresentado em V Symposium of the PhD Programme on Molecular and Environmental Biology, 2019.
  14. Mendes, FS; Amaral, Leslie; Côrte-Real, M; Sousa, MJ; FC1A-F4E3-6141. "How carbon source affects the sensitivity to the anti-cancer agent cisplatin". Trabalho apresentado em I Jornadas da Ciência: Concentra o Conhecimento, 2019.
  15. Mendes, FS; Amaral, L; Martins, V; Côrte-Real, M; Sousa, MJ; FC1A-F4E3-6141. "The effect of carbon source in the sensitivity to the anti-cancer agent cisplatin". Trabalho apresentado em IV Symposium of the PhD Programme on Molecular and Environmental Biology, 2018.
Tese / Dissertação
  1. Chaves, Susana Alexandra Rodrigues; Alves, Sara Cristina Sequeira; Mendes, Filipa Diana da Silva. "Bax activation by PKC modulation: an attractive target to eliminate cancer cells". Mestrado, Universidade do Minho Escola de Ciências, 2017. http://hdl.handle.net/1822/45647.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/12/21 Bio-reduction of wine volatile acidity using yeast cells Winetunning Final Workshop
(Braga, Portugal)
2023/02/08 Yeast a novel tool for the detection and assessment of ecological risks of fungicides”. I Symposium PhD Bio
(Braga, Portugal)
2021/12/06 Bio-deteção de fungicidas azólicos At the workshop “Uma abordagem funcional para compreender a interação entre a poluição por fungicidas e os processos do ecossistema mediados por fungos”, promoted by FunG-Eye project
Universidade do Minho (Braga, Portugal)
2021/03/31 Bio-Detection of fungicides: An alternative to traditional methods” At the webinar "Bio-Deteção e Efeitos ecológicos de fungicidas em sistemas aquáticos: modelos biológicos e resultados do projeto FunG-Eye"¿, promoted by FunG-Eye project
Universidade do Minho (Braga, Portugal)
2019/03/20 Carbon source affects the sensitivity to the anti-cancer agent cisplatin Biology Department Seminar
Universidade do Minho, Escola de Ciências, Departamento de Biologia (Braga, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020/04 - 2020/07 A yeast biosensor to detect azole contaminants
Coorientador
Bioquímica (Licenciatura/Bacharelato)
Universidade do Minho, Portugal
2019/03 - 2019/07 A yeast biosensor to detect azole contaminants
Coorientador
Bioquímica (Licenciatura/Bacharelato)
Universidade do Minho, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2019/01/04 - Atual Ongoing participation in Pint of Science, which is an international event aiming to promote science for general society in bars. I am an event manager of the theme "Com Pés e Cabeça", which covers topics from medicine to molecular and cellular biology. (2019/05/20 - 2019/05/22)
Encontro (Membro da Comissão Organizadora)
2019/03/14 - 2019/03/14 Co-organized the workshop "Fluorescent Molecular Probes", in the scope of "Jornadas da Ciência: Concentra o Conhecimento. In this workshop, we used different fluorescent molecular probes and the fluorescence microscope to visualize several cellular compartments using cell lines and yeast cells as models. During the workshop, we discussed the various types of probes and their characteristics, as well as practical applications. (2019/03/14 - 2019/03/14)
Oficina (workshop) (Coorganizador)
Universidade do Minho, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2018/12/04 - Atual Volunteer in the in initiative "Investigadores voltam à escola" organized by the School of Sciences, University of Minho. The goal of this project is that researchers from the School of Sciences interact with high school students and explain their research, such as day-to-day lab work, their academic background, personal and professional journey, and passion for science.
Outro
Investigadores Voltam à Escola
Universidade do Minho Escola de Ciências, Portugal
2019/03/15 - 2020/09 Volunteer in the initiative "Programas de visitas à Escola de Ciências" organized by the School of Sciences, University of Minho. The aim of this project is to show the teaching and research opportunities of the School of Sciences, University of Minho. This project offers several activities that include guided visits to the facilities and laboratories, participation in hands-on activities, experimental demonstrations, lectures, among others. So far, I co-organized a hands-on experiment using fluorescence microscopy.
Outro
Programas de visitas à Escola de Ciências
Universidade do Minho Escola de Ciências, Portugal
2019/03/11 - 2019/03/15 Attended the conference "1st Journeys of Science of University of Minho". This event aimed to share knowledge in the area of biological and environmental sciences. Several speakers gave seminars on both fundamental and applied science.
Congresso
I Jornadas da Ciência: [Ciência] - Concentra o Conhecimento
Universidade do Minho, Portugal
2019/03/13 - 2019/03/13 Attended the workshop "Poluição vs Doença: a verdade escondida sobre os impactos ecológicos dos pesticidas ". This workshop introduced the use of pesticides in agriculture and the pollution vs. disease problem. It was also an opportunity to get acquainted with a biological model that provides innovative knowledge on the ecological impacts of these agrochemicals on non-target fungi, a subject of the proposed thesis.
Oficina (workshop)
I Jornadas da Ciência: [Ciência] - Concentra o Conhecimento
Universidade do Minho, Portugal
2019/03/11 - 2019/03/11 Attended the workshop "Contaminantes emergentes - O presente e o futuro a nível global". This workshop introduced the use of emerging chemical contaminants on a global and constituent scale, currently a focus of great concern.
Oficina (workshop)
I Jornadas da Ciência: [Ciência] - Concentra o Conhecimento
Universidade do Minho, Portugal
2018/10/15 - 2018/10/17 Attended the event "INL SUMMIT| Nanotecnology: An enabler for the new economy" where visionaries from around the world came together to share, interact and collaborate with scientists, business experts, entrepreneurs, artists, changemakers and innovators.
Conferência
“INL SUMMIT| Nanotecnology: An enabler for the new economy”
International Iberian Nanotechnology Laboratory, Portugal
2018/10 - 2018/10 Attended the event IV Symposium of the PhD Programme on Molecular and Environmental Biology. In this symposium there is a presentation of the work developed in the CBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers.
Simpósio
“IV Symposium of the PhD Programme on Molecular and Environmental Biology”
Universidade do Minho Escola de Ciências, Portugal
2018/09/28 - 2018/09/28 Volunteered in the event European researchers night, organized by the School of Sciences, University of Minho.
Exposição
European researchers’ night
Universidade do Minho Escola de Ciências, Portugal
2015/11 - 2015/11 Attended the event III Symposium of the PhD Programme on Molecular and Environmental Biology. This symposium included presentations of work developed atCBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers.
Simpósio
III Symposium of the PhD Programme on Molecular and Environmental Biology¿
Universidade do Minho Escola de Ciências, Portugal
2015/09/29 - 2015/10/03 Attended the "11th International meeting on yeast apoptosis (IMYA 2015) conference, which brought together researchers who explore yeast as a preferred cellular model for applied research with an impact on biomedicine and biotechnology, in order to develop new therapeutic strategies in the field of apoptosis, programmed cell death, aging and in stress response mechanisms.
Congresso
"11th International meeting on yeast apoptosis (IMYA 2015)”
Universidade do Minho Escola de Ciências, Portugal

Universidade do Minho Escola de Medicina, Portugal
2014/11 - 2014/11 Attended the event II Symposium of the PhD Programme on Molecular and Environmental Biology. In this symposium, the work developed in the CBMA (Center for Molecular and Environmental Biology) within the scope of the doctoral program of molecular and environmental biology, as well as lectures by invited researchers, were presented.
Simpósio
II Symposium of the PhD Programme on Molecular and Environmental Biology¿
Universidade do Minho Escola de Ciências, Portugal
2014/09/27 - 2014/09/27 Volunteered in the event European researchers night, organized by the School of Sciences, University of Minho.
Exposição
European researchers night
Universidade do Minho Escola de Ciências, Portugal
2014 - 2014 Attended the event "Palestra de Ciências Forenses" organized by NEBUP- Núcleo de estudantes de biologia.
Seminário
Palestra de Ciências Forenses
Universidade do Porto, Portugal

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2021 - Atual Sub-coordinator of the PhD Students' Group of the Centre of Molecular and Environmental Biology
Coordenador
Universidade do Minho, Portugal
2020 - 2021 Secretary of the PhD Students' Group of the Centre of Molecular and Environmental Biology
Membro
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Tutoria

Tópico Nome do aluno
2021/10/01 - Atual Novel yeast-based biosensors for drug discovery Mariana Mota Gomes
2020/10/01 - 2021/12/31 Toxicogenomics - based testes for hazard assessement Tiago André Vidal Cardoso
2020/10/01 - 2021/12/31 Novel yeast-based biosensor for environmental monitoring Eduarda Maria Oliveira Miranda
Distinções

Prémio

2023 Early career investigator fellowship to attendance in 31st International Conference on Yeast Genetics and Molecular Biology, 20-25 August, Florence, Italy
Federation Of European Microbiological Societies, Países Baixos
2018 Concurso FoodValorization
NewFood Project: Universidade do Minho, Universidade do Porto, Universidade de Trás os Montes e Alto Douro, Universidade Católica, Portugal