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Rute Nunes is currently an Associate Researcher at Nanomedicines & Translational Drug Delivery Group at Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Portugal and an Invited Assistant Professor at Instituto Universitário de Ciências da Saúde (IUCS), Gandra, Portugal. She graduated in Pharmaceutical Sciences in 2013 and holds a PhD in Biomedical Sciences (2018) from Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), University of Porto, Portugal in collaboration with Instituto de Investigação do Medicamento (iMEd.ULisboa), Faculdade de Farmácia, Universidade de Lisboa. Her research is focused on the development of nanotechnology-based drug delivery systems for mucosal drug delivery. In the last two years, she also conducted research in the cell replacement therapy field, focusing in the combination of stem cell-based therapies and smart nanomedicines for Type 1 Diabetes Mellitus treatment. Her broad research interests include nanomedicine, nanotechnology-based systems for drug delivery, biomaterials and cell-based therapies. She has a broad experience in the development and characterization of polymeric nanosystems, cell-based assays and in vivo experiments using healthy and diseased animal models. She published 25 papers in international peer reviewed (ISI) journals and six book chapters with a h-index of 17 and a total of 706 citations. She interacted with 84 collaborators co-authorship of scientific work. As a researcher, she describes herself as a passionate and versatile researcher, capable of integrating different projects, being highly adaptable to different situations and challenges. Besides being a dedicated worker, she is always enthusiastic to learn and develop new skills.
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Identification

Personal identification

Full name
Rute Sofia Gonçalves Nunes

Citation names

  • Nunes, Rute

Author identifiers

Ciência ID
6713-C9CB-54D6
ORCID iD
0000-0001-8633-4404
Scopus Author Id
7102596304

Websites

Knowledge fields

  • Medical and Health Sciences
  • Engineering and Technology - Nano-technology - Nano-materials

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Projects

Grant

Designation Funders
2018/07 - 2019/06 NETDIAMOND - New targets in diastolic heart failure: from comorbidities to personalized medicine
C441894815-00037491
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 European Structural and Investment Funds/COMPETE 2020/POCI/PAC
2014/01 - 2017/12 Nanotechnology-Based Strategies for Rectal Anti-HIV Pre-Exposure Prophylaxis
SFRH/BD/96519/2013
PhD Student Fellow
Fundação para a Ciência e a Tecnologia (FCT)

Contract

Designation Funders
2019/07 - 2022/02/28 PANCREASMIMETIC - Establishment of a multifunctional stimuli-responsive pancreas mimetic
PTDC/CTM-CER/30046/2017
POCI-01-0145-FEDER-030466
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2024/01/01 - Current Oxidative-responsive nanomedicines for managing inflammatory bowel disease
1247220
Co-Principal Investigator (Co-PI)
Crohn's & Colitis Foundation
Ongoing
2022/01/01 - Current HORIZON-HLTH-2021-TOOL-06: GENEGUT - Oral delivery of encapsulated RNA nanotherapeutics for targeted treatment of ileal Crohn's disease
GENEGUT 101057491
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 European Comission
Ongoing
2022/07/01 - 2023/06/30 Oxidative-responsive nanomedicines for managing inflammatory bowel disease
937924
Co-Principal Investigator (Co-PI)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Crohn's & Colitis Foundation
Ongoing
2017 - 2018/12 Nano-ThERM: Nanopartículas em Enema Termossensível para o Desenvolvimento de Microbicidas Retais Anti-VIH
PGG/002/2016
Researcher
Gilead Sciences Lda
Concluded
2016 - 2018 Filmes vaginais contendo nanopartículas carregadas com fármacos como alternativa à profilaxia de préexposição oral com tenofovir/emtricitabina
PGG/046/2015
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Gilead Sciences Lda
Concluded
2016/04 - 2017/03 ElectrospunnScar-CESPU-2016: Development of biocomposites fibrous scaffolds as topical 5-fluorouracil carriers for inhibiting hypertrophic scar.
ElectrospunnScar-CESPU-2016
Researcher
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2016 - 2017 Nano2FcRn-CESPU-2016: Bioengineered FcRn-targeting nanoparticles for intestinal delivery of biopharmaceuticals.
Nano2FcRn-CESPU-2016
Researcher
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
Outputs

Publications

Book chapter
  1. Marques, Joana Moreira; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "A demanding path from iPSCs toward pancreatic ß- and a-cells". In Recent Advances in iPSC-Derived Cell Types, 227-256. Elsevier, 2021.
    10.1016/b978-0-12-822230-0.00002-8
  2. Nunes, Rute; Sarmento, Bruno; Reis, Salette; Fonte, Pedro. "Oral nanotechnological approaches for colon-specific drug delivery". In Nanoparticles in the Life Sciences and Biomedicine, edited by Neves, Ana Rute; Reis, Salette, 133-158. Panstanford Publishing, 2018.
  3. Nunes, Rute; Sousa, Carole; Sarmento, Bruno; das Neves, José. "Nanotechnology-Based Systems for Microbicide Development". In Handbook of Clinical Nanomedicine, edited by Bawa, Raj; Audette, Gerald F.; Rubinstein, Israel. Nova Iorque, United States: Jenny Stanford Publishing, 2016.
  4. Nunes, R.; Sousa, C.; Sarmento, B.; Das Neves, J.. "Nanotechnology-based systems for microbicide development". 1445-1491. 2016.
  5. Nunes, R.; Silva, C.; Chaves, L.. "Tissue-based in vitro and ex vivo models for intestinal permeability studies". 203-236. 2016.
  6. Nunes, R.; Sousa, C.; Sarmento, B.; Das Neves, J.. "Nanotechnology-based systems for microbicide development". 415-458. 2014.
Conference poster
  1. Silva F. R., Andreia; Monteiro, Mariana; Nunes, Rute; Braga, Susana Santos; Sarmento, Bruno; Coimbra, Manuel A.; Silva, Artur M. S.; Cardoso, Susana M.. "Is it necessary to use delivery vehicles for incorporating resveratrol into bread?". Paper presented in 2nd Dare2Change International Conference, Porto, Portugal, 2023.
  2. Barros, Andreia; Nunes, Rute; Sarmento, Bruno. "Fighting Inflammatory Bowel Diseases with a ROS-responsive approach". 2023.
  3. Moreira Marques, Joana; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "Development of GLP-1 analogue-loaded nanoparticles in a bioartificial pancreas to treat type I Diabetes". Paper presented in IDF World Diabetes Congress 2022, 2022.
  4. Barros, Andreia; Nunes, Rute; Sarmento, Bruno. "Stimulus-responsive nanosystem for effective peptide delivery for the treatment of IBD". 2022.
  5. Barros, Andreia; Nunes, Rute; Sarmento, Bruno. "Cleavable mucus-diffusive nanosystem for effective peptide delivery for the treatment of IBD". Paper presented in CRS 2022 annual meeting, Montreal, Canada, 2022.
  6. Barros, Andreia; Nunes, Rute; Sarmento, Bruno. "Fighting Inflammatory Bowel Diseases with a stimulus-responsive approach". 2022.
  7. Moreira Marques, Joana; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "Development of glucose-responsive nanoparticles towards the design of a bioartificial pancreas for Diabetes therapy". Paper presented in 31st Conference of the European Society for Biomaterials, 2021.
  8. Silva, Andreia F.R.; Monteiro, Mariana; Nunes, Rute; Braga, Susana S.; Sarmento, Bruno; Coimbra, Manuel A.; Silva, Artur M.S.; Cardoso, Susana M.. "Applications of resveratrol delivery systems for functional bread". Paper presented in 7th Portuguese Young Chemists Meeting :7PYCHEM, 2021.
  9. Barros, Andreia; Nunes, Rute; Sarmento, Bruno. "Cleavable mucus-penetrating nanosystem for effective delivery of peptide for the treatment of inflammatory bowel disease". 2021.
  10. Nunes, Rute; Silva F. R., Andreia; Monteiro, Mariana; Braga, Susana Santos; Sarmento, Bruno; Coimbra, Manuel A.; Silva, Artur M. S.; Cardoso, Susana M.. "Bread enriched with resveratrol: influence of the delivery vehicles". Paper presented in Iberphenol, 2020.
  11. Nunes, Rute; das Neves, José; Sarmento, Bruno. "Zein nanoparticles as potential oral carriers for resveratrol". Paper presented in XIIIth Spanish-Portuguese Conference on Controlled Drug Delivery, 2020.
  12. Marques, Joana Moreira; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "Bioengineered glucose-responsive nanoparticles in artificial pancreas for Diabetes therapy". Paper presented in XIIIth Spanish-Portuguese Conference on Controlled Drug Delivery, 2020.
  13. Moreira Marques, Joana; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "NanoIntelligent bioartificial pancreas for Diabetes therapy". Paper presented in 47th Annual Meeting of the Controlled Release Society (Virtual), 2020.
  14. Barros, Andreia; Nunes, Rute; Sarmento, Bruno. "Cleavable mucus-penetrating nanosystem for effective delivery of peptide for the treatment of inflammatory bowel disease". Paper presented in 3rd PhDay, i3S, Porto, Portugal, 2020.
  15. Faria, Maria; Bogas, Sarah; Nunes, Rute; Lanceros-Mendez, Senentxu; das Neves, José; LÚCIO, MARLENE; Viseu, Teresa. "Tenofovir disoproxil fumarate/emtricitabine-loaded electrospun fibers for vaginal administration and prevention of HIV transmission". Paper presented in Jornadas CF-UM-UP, University of Minho, Braga, Portugal, 2019.
  16. Nunes, Rute; das Neves, José; Vasconcelos, Teófilo; Sarmento, Bruno. "Zein nanoparticles as a strategy to improve the bioavailability of resveratrol". Paper presented in Nanomed Europe 2019, 2019.
  17. Marques, Joana Moreira; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "Glucose-responsive nanoparticles embedded in a 3D-engineered pancreas". Paper presented in Training School on Advanced spectroscopic analytical methods and new technologies in drug delivery, 2019.
  18. Moreira Marques, Joana; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "Stimuli-responsive nanoparticles for pancreas mimetic construct". Paper presented in 8th i3S Annual Meeting, 2019.
  19. Moreira Marques, Joana; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "Glucose-responsive nanoparticles embedded in a 3D-engineered pancreas". Paper presented in Training School on Advanced spectroscopic analytical methods and new technologies in drug delivery, 2019.
  20. Moreira Marques, Joana; Nunes, Rute; Florindo, Helena; Ferreira, Domingos; Sarmento, Bruno. "Multifunctional stimuli-responsive pancreas mimetic". Paper presented in 2nd PhDay - PhD countdown: a time for Science - i3S, 2019.
  21. Fonseca, Filipa; Moreira Marques, Joana; Oliveira, Ana Vanessa; Nunes, Rute; Sarmento, Bruno. "Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy". Paper presented in 2019 Controlled Release Society (CRS) Annual Meeting & Exposition, 2019.
  22. Ferreira, Avelino; Nunes, Rute; Bártolo, Inês; Taveira, Nuno; Sarmento, Bruno; das Neves, José. "The Potential of Saquinavir-loaded Nanoparticles for Rectal Microbicide Development". Paper presented in HIVR4P, 2018.
  23. Nunes, Rute; Araújo, Francisca; Barreiros, Luísa; Segundo, Marcela A.; Sarmento, Bruno. "Mucus-diffusive nanoparticles provide enhanced local pharmacokinetics of efavirenz following rectal administration". Paper presented in HIVR4P, 2018.
  24. Nunes, Rute; Bártolo, Inês; Taveira, Nuno; das Neves, José; Sarmento, Bruno. "Efavirenz-loaded PLGA nanoparticles as potential rectal microbicides". Paper presented in 24th International Conference on Bioencapsulation, 2016.
  25. das Neves, José; Cunha-Reis, Cassilda; Barreiros, Luisa; Machado, Alexandra; Araújo, Francisca; Nunes, Rute; Sarmento, Bruno. "Pharmacokinetics and safety of vaginal tenofovir/efavirenz-loaded nanoparticles-in-film in mice". Paper presented in HIV Research for Prevention 2016: AIDS Vaccine, Microbicide and ARV-based Prevention Science (HIVR4P), Chicago, IL, USA, 2016., 2016.
  26. Nunes, Rute; das Neves, José; Sarmento, Bruno. "Fourteen-day safety of daily vaginal administration of dapivirine-loaded nanoparticles in a mouse model". Paper presented in HIVR4P, 2014.
Journal article
  1. Ferreira, Bárbara; Barros, Andreia S.; Leite Pereira, Catarina; Viegas, Juliana; das Neves, José; Nunes, Rute; Sarmento, Bruno. "Trends in 3D models of inflammatory bowel disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2024): 167042. http://dx.doi.org/10.1016/j.bbadis.2024.167042.
    Published • 10.1016/j.bbadis.2024.167042
  2. Cristelo, Cecília; Nunes, Rute; Pinto, Soraia; Marques, Joana Moreira; Gama, Francisco Miguel; Sarmento, Bruno. "Targeting ß Cells with Cathelicidin Nanomedicines Improves Insulin Function and Pancreas Regeneration in Type 1 Diabetic Rats". ACS Pharmacology & Translational Science 6 10 (2023): 1544-1560. http://dx.doi.org/10.1021/acsptsci.3c00218.
    10.1021/acsptsci.3c00218
  3. Silva, Andreia F.R.; Monteiro, Mariana; Nunes, Rute; Baião, Ana; Braga, Susana S.; Sarmento, Bruno; Coimbra, Manuel A.; Silva, Artur M.S.; Cardoso, Susana M.. "Bread enriched with resveratrol: Influence of the delivery vehicles on its bioactivity". Food Bioscience 49 (2022): 101887. http://dx.doi.org/10.1016/j.fbio.2022.101887.
    10.1016/j.fbio.2022.101887
  4. Carvalho, Ana Margarida; Nunes, Rute; Sarmento, Bruno. "From pluripotent stem cells to bioengineered islets: A challenging journey to diabetes treatment". European Journal of Pharmaceutical Sciences 172 (2022): 106148. http://dx.doi.org/10.1016/j.ejps.2022.106148.
    10.1016/j.ejps.2022.106148
  5. Nunes, Rute; Bogas, Sarah; Faria, Maria João; Gonçalves, Hugo; LÚCIO, MARLENE; Viseu, Teresa; Sarmento, Bruno; das Neves, José. "Electrospun fibers for vaginal administration of tenofovir disoproxil fumarate and emtricitabine in the context of topical pre-exposure prophylaxis". (2021): https://www.biorxiv.org/content/10.1101/2021.02.01.429162v1.full.
    Submitted
  6. Azevedo, Cláudia; Nilsen, Jeannette; Grevys, Algirdas; Nunes, Rute; Andersen, Jan Terje; Sarmento, Bruno. "Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin". Journal of Controlled Release 327 (2020): 161-173. http://dx.doi.org/10.1016/j.jconrel.2020.08.005.
    Published • 10.1016/j.jconrel.2020.08.005
  7. Cristelo, Cecília; Azevedo, Cláudia; Marques, Joana Moreira; Nunes, Rute; Sarmento, Bruno. "SARS-CoV-2 and diabetes: New challenges for the disease". Diabetes Research and Clinical Practice 164 (2020): 108228. http://dx.doi.org/10.1016/j.diabres.2020.108228.
    Published • 10.1016/j.diabres.2020.108228
  8. Nunes, Rute; Baião, Ana; Monteiro, Diana; das Neves, José; Sarmento, Bruno. "Zein nanoparticles as low-cost, safe, and effective carriers to improve the oral bioavailability of resveratrol". Drug Delivery and Translational Research (2020): http://dx.doi.org/10.1007/s13346-020-00738-z.
    Published • 10.1007/s13346-020-00738-z
  9. Nunes, Rute; Neves, José das; Sarmento, Bruno. "Nanoparticles for the regulation of intestinal inflammation: opportunities and challenges". Nanomedicine 14 19 (2019): 2631-2644. http://dx.doi.org/10.2217/nnm-2019-0191.
    Published • 10.2217/nnm-2019-0191
  10. Abeer, Muhammad Mustafa; Meka, Anand Kumar; Pujara, Naisarg; Kumeria, Tushar; Strounina, Ekaterina; Nunes, Rute; Costa, Ana; et al. "Rationally Designed Dendritic Silica Nanoparticles for Oral Delivery of Exenatide". Pharmaceutics 11 8 (2019): 418. http://dx.doi.org/10.3390/pharmaceutics11080418.
    10.3390/pharmaceutics11080418
  11. Martins, Cláudia; Araújo, Francisca; Gomes, Maria João; Fernandes, Carlos; Nunes, Rute; Li, Wei; Santos, Hélder A.; Borges, Fernanda; Sarmento, Bruno. "Using microfluidic platforms to develop CNS-targeted polymeric nanoparticles for HIV therapy". European Journal of Pharmaceutics and Biopharmaceutics 138 (2019): 111-124. http://dx.doi.org/10.1016/j.ejpb.2018.01.014.
    10.1016/j.ejpb.2018.01.014
  12. Mesquita, Letícia; Galante, Joana; Nunes, Rute; Sarmento, Bruno; das Neves, José. "Pharmaceutical Vehicles for Vaginal and Rectal Administration of Anti-HIV Microbicide Nanosystems". Pharmaceutics 11 3 (2019): 145. http://dx.doi.org/10.3390/pharmaceutics11030145.
    10.3390/pharmaceutics11030145
  13. Melo, Mélanie; Nunes, Rute; Sarmento, Bruno; das Neves, José. "Colorectal distribution and retention of polymeric nanoparticles following incorporation into a thermosensitive enema". Biomaterials Science 7 9 (2019): 3801-3811. http://dx.doi.org/10.1039/c9bm00759h.
    10.1039/c9bm00759h
  14. Nunes, R.; Araújo, F.; Barreiros, L.; Bártolo, I.; Segundo, M.A.; Taveira, N.; Sarmento, B.; Das Neves, J.. "Correction: Noncovalent PEG Coating of Nanoparticle Drug Carriers Improves the Local Pharmacokinetics of Rectal Anti-HIV Microbicides (ACS Applied Materials and Interfaces (2018) 10:41 (34942?34953) DOI: 10.1021/acsami.8b12214)". ACS Applied Materials and Interfaces 11 4 (2019): 4701-4701. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060877490&partnerID=MN8TOARS.
    10.1021/acsami.8b22242
  15. Melo, Mélanie; Nunes, Rute; Sarmento, Bruno; das Neves, José. "Rectal administration of nanosystems: from drug delivery to diagnostics". Materials Today Chemistry 10 (2018): 128-141. http://dx.doi.org/10.1016/j.mtchem.2018.09.001.
    10.1016/j.mtchem.2018.09.001
  16. Fernandes, Carlos; Martins, Cláudia; Fonseca, André; Nunes, Rute; Matos, Maria João; Silva, Renata; Garrido, Jorge; et al. "PEGylated PLGA Nanoparticles As a Smart Carrier to Increase the Cellular Uptake of a Coumarin-Based Monoamine Oxidase B Inhibitor". ACS Applied Materials & Interfaces 10 46 (2018): 39557-39569. http://dx.doi.org/10.1021/acsami.8b17224.
    10.1021/acsami.8b17224
  17. Nunes, Rute; Araújo, Francisca; Barreiros, Luisa; Bártolo, Inês; Segundo, Marcela A.; Taveira, Nuno; Sarmento, Bruno; das Neves, José. "Noncovalent PEG Coating of Nanoparticle Drug Carriers Improves the Local Pharmacokinetics of Rectal Anti-HIV Microbicides". ACS Applied Materials & Interfaces 10 41 (2018): 34942-34953. http://dx.doi.org/10.1021/acsami.8b12214.
    10.1021/acsami.8b12214
  18. Belubbi, Tejashree; Shevade, Sukhada; Dhawan, Vivek; Sridhar, Vinay; Majumdar, Anuradha; Nunes, Rute; Araújo, Francisca; et al. "Lipid Architectonics for Superior Oral Bioavailability of Nelfinavir Mesylate: Comparative in vitro and in vivo Assessment". AAPS PharmSciTech 19 8 (2018): 3584-3598. http://dx.doi.org/10.1208/s12249-018-1156-3.
    10.1208/s12249-018-1156-3
  19. Nunes, Rute; Araújo, Francisca; Tavares, Joana; Sarmento, Bruno; das Neves, José. "Surface modification with polyethylene glycol enhances colorectal distribution and retention of nanoparticles". European Journal of Pharmaceutics and Biopharmaceutics 130 (2018): 200-206. http://dx.doi.org/10.1016/j.ejpb.2018.06.029.
    10.1016/j.ejpb.2018.06.029
  20. Cunha-Reis, Cassilda; Machado, Alexandra; Barreiros, Luísa; Araújo, Francisca; Nunes, Rute; Seabra, Vítor; Ferreira, Domingos; et al. "Nanoparticles-in-film for the combined vaginal delivery of anti-HIV microbicide drugs". Journal of Controlled Release 243 (2016): 43-53. http://dx.doi.org/10.1016/j.jconrel.2016.09.020.
    10.1016/j.jconrel.2016.09.020
  21. Sadio, Ana; Amaral, Ana L.; Nunes, Rute; Ricardo, Sara; Sarmento, Bruno; Almeida, Raquel; Tsukamoto, Hidekazu; das Neves, José. "A Mouse Intra-Intestinal Infusion Model and its Application to the Study of Nanoparticle Distribution". Frontiers in Physiology 7 (2016): http://dx.doi.org/10.3389/fphys.2016.00579.
    10.3389/fphys.2016.00579
  22. Machado, Alexandra; Cunha-Reis, Cassilda; Araújo, Francisca; Nunes, Rute; Seabra, Vítor; Ferreira, Domingos; das Neves, José; Sarmento, Bruno. "Development and in vivo safety assessment of tenofovir-loaded nanoparticles-in-film as a novel vaginal microbicide delivery system". Acta Biomaterialia 44 (2016): 332-340. http://dx.doi.org/10.1016/j.actbio.2016.08.018.
    10.1016/j.actbio.2016.08.018
  23. Andrade, Fernanda; Fonte, Pedro; Costa, Ana; Reis, Cassilda Cunha; Nunes, Rute; Almeida, Andreia; Ferreira, Domingos; Oliva, Mireia; Sarmento, Bruno. "Pharmacological and toxicological assessment of innovative self-assembled polymeric micelles as powders for insulin pulmonary delivery". Nanomedicine 11 17 (2016): 2305-2317. http://dx.doi.org/10.2217/nnm-2016-0045.
    10.2217/nnm-2016-0045
  24. das Neves, José; Nunes, Rute; Rodrigues, Francisca; Sarmento, Bruno. "Nanomedicine in the development of anti-HIV microbicides". Advanced Drug Delivery Reviews 103 (2016): 57-75. http://dx.doi.org/10.1016/j.addr.2016.01.017.
    10.1016/j.addr.2016.01.017
  25. Sadio A; Amaral AL; Nunes R; Ricardo S; Sarmento B; Almeida R; Tsukamoto H; das Neves J. "A Mouse Intra-Intestinal Infusion Model and its Application to the Study of Nanoparticle Distribution.". (2016): http://europepmc.org/abstract/med/27965585.
  26. das Neves, José; Nunes, Rute; Machado, Alexandra; Sarmento, Bruno. "Polymer-based nanocarriers for vaginal drug delivery". Advanced Drug Delivery Reviews 92 (2015): 53-70. http://dx.doi.org/10.1016/j.addr.2014.12.004.
    10.1016/j.addr.2014.12.004
  27. Nunes, Rute; Sarmento, Bruno; das Neves, José. "Formulation and delivery of anti-HIV rectal microbicides: Advances and challenges". Journal of Controlled Release 194 (2014): 278-294. http://dx.doi.org/10.1016/j.jconrel.2014.09.013.
    10.1016/j.jconrel.2014.09.013
Thesis / Dissertation
  1. Nunes, Rute. "Nanotechnology-based strategies for rectal anti-HIV pre-exposure prophylaxis". PhD, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2018. https://repositorio-aberto.up.pt/handle/10216/117712.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023 Surpassing intestinal mucus, targeting Inflammatory Bowel Disease Oral Delivery Focus Group of the Controlled Release Society
Online
2023 Fighting Inflammatory Bowel Disease with a ROS-responsive approach
ICBAS (Porto, Portugal)
2022 Cleavable mucus-diffusive nanosystem for effective peptide delivery for the treatment of IBD CRS 2022 Annual Meeting
Controlled Release Society (Montreal, Canada)
2020/06/29 Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin 47th Controlled Release Society Annual Meeting
Controlled Release Society
2019 Impact of PEG coating in the distribution and retention of PLGA nanoparticles in colorectal tissues 2nd SPLC-CRS Young Scientists Meeting
SPLC-CRS Local Chapter (Santiago de Compostela, Spain)
2019 Multifunctional stimuli-responsive pancreas mimetic New Frontiers in Biofabrication: From Biomolecules to Tissues and Organs
European Network of Bioadhesion Expertise (ENBA) - COST Action CA 15216 (Leuven, Belgium)
2018 Efavirenz-loaded poly(ethylene glycol)-modified nanoparticles as potential rectal anti-HIV microbicides nanoPT2018 International Conference
NanoPT (Lisbon, Portugal)
2017 Efavirenz-loaded poly (ethylene oxide)-modified nanoparticles as potential rectal anti-HIV microbicides 6th FIP Pharmaceutical Sciences World Congress
International Pharmaceutical Federation (Sweden)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020 - Current Cleavable peguilated mucus-penetrating nanosystems for effective intestinal peptide delivery in the treatment of inflammatory bowel disease
Co-supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - Current From pluripotent stem cells towards a bioengineered pancreas to treat T1DM
Co-supervisor
 Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2020 - 2020 Research Trainee
Co-supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2019 Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
Co-supervisor
 Bioquímica para a Saúde
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019 - Current 2019 Controlled Release Society Annual Meeting & Exposition, July 21-24 2019, Palacio de Congresos de València, Valencia, Spain
Meeting
 2019 Controlled Release Society Annual Meeting & Exposition
2023/09/25 - 2023/10/24 Course Building and Leading Research Teams
2023/10/12 - 2023/10/12 Life Science Intellectual Property: Management and Exploitation, 2nd Edition
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/10 - 2021/07 Training Course in Research Ethics and Integrity
Other
 Training Course in Research Ethics and Integrity
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/10/22 - 2020/10/22 VII BiotechHealth Annual Symposium - From bench to bedside: Found in Translation
Symposium
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/07/20 - 2020/07/21 Research Project Management
Other
 Research Project Management Course
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/06/29 - 2020/07/02 47th Controlled Release Society Annual Meeting (Virtual)
Meeting
 2020 CRS Virtual Annual Meeting
2020/01/22 - 2020/01/24 XIIIth Spanish-Portuguese Conference on Controlled Drug Delivery
Conference
2019/11/28 - 2019/11/29 8th i3S Annual Meeting
Meeting
 8th i3S Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/10/25 - 2019/10/27 1st Discoveries Forum on Regenerative and Precision Medicine
Conference
 1st Discoveries Forum on Regenerative and Precision Medicine
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Minho, Portugal
2019 - 2019 3rd Training School on Bioinspired Adhesive Hydrogels and Polymers, October 21-25 2019
Workshop
 3rd Training School on Bioinspired Adhesive Hydrogels and Polymers
Universidade de Aveiro, Portugal
2019 - 2019 1st Discoveries Forum on Regenerative and Precision Medicine, September 25-27 2019, Porto Palácio Hotel & Spa, Porto, Portugal
Conference
 1st Discoveries Forum on Regenerative and Precision Medicine
Universidade do Minho, Portugal
2019 - 2019 Interrogations at the Biointerface - 7th Advanced Summer School: "Do organoids fill the in vitro/in vivo gap?", June 27-28 2019, Biblioteca Almeida Garret, Porto, Portugal
Workshop
 Interrogations at the Biointerface – 7th Advanced Summer School: “Do organoids fill the in vitro/in vivo gap?
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 - 2019 Jornadas PERIN - International programmes for research and innovation funding: opportunities for health, translational and clinical research, May 20 2019, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
Other
 Jornadas PERIN - International programmes for research and innovation funding: opportunities for health, translational and clinical research
Agência Nacional de Inovação SA, Portugal
2019 - 2019 2nd SPLC-CRS Young Scientists Meeting, January 23 2019, School of Medicine of the University of Santiago de Compostela, Santiago de Compostela, Spain.
Meeting
 2nd SPLC-CRS Young Scientists Meeting
2018 - 2018 HIVR4P 2018, October 21-25 2018, Madrid Marriott Auditorium Hotel & Conference Center, Madrid, Spain
Conference
 HIVR4P
2018 - 2018 NanoPT2018 International Conference, February 7-9 2018, Universidade Lusófona de Humanidades e Tecnologias, Lisboa, Portugal.
Conference
 NanoPT2018 International Conference
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2016 - 2016 24th International Conference on Bioencapsulation, September 21-23, 2016, Universidade Lusófona de Humanidades e Tecnologias, Lisboa, Portugal
Conference
 24th International Conference on Bioencapsulation
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2015 - 2015 Course in Laboratory Animal Science - Category C with FELASA Accreditation (accreditation number 020/08), September 7-18, 2015, Institute for Molecular and Cell Biology (IBMC), I3S, Porto, Portugal
Other
 Course in Laboratory Animal Science - Category C with FELASA Accreditation
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015 - 2015 Advanced Summer School 2015 – Interrogations at the Biointerface, The nanomedicine interface, June-July 29-3, 2015, Porto, Portugal
Workshop
 Advanced Summer School 2015 – Interrogations at the Biointerface, The nanomedicine interface
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2014 - 2014 SFNano Workshop 2014, Relevant tools and models for the translation of advanced drug delivery, October 2-4, 2014, Porto, Portugal
Workshop
 SFNano Workshop 2014, Relevant tools and models for the translation of advanced drug delivery
2014 - 2014 Notions of Self-exploring theories of immunity, September 30, 2014, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), University of Porto, Porto, Portugal
Symposium
 Notions of Self-exploring theories of immunity
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - 2014 Flow Cytometry – Fundamentals and Applications, June 19-20, 2014, Instituto de Biologia Molecular e Celular (IBMC), Porto, Portugal
Workshop
 Flow Cytometry – Fundamentals and Applications
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2020/12/02 Desenvolvimento e otimização de uma formulação tópica com extrato de cascas de Castanea sativa baseado no conceito "Quality by design"
(Thesis) Main arguer
 Nágilla Silva de Oliveira (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/10/25 Desenvolvimento e caracterização de um creme hidrófilo com extrato de cascas de Castanea sativa
(Thesis) Main arguer
 Sabrina Padoin Tassotti (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Association member

Society Organization name Role
2023 - Current European Crohn´s and Colitis Organisation (ECCO) Association member
2021 - Current International Society for Stem Cell Research (ISSCR) Association member
2019 - Current Young Scientist Committee - CRS Ambassador
2018 - Current Controlled Release Society Member
2017 - Current Spanish Portuguese Local Chapter-Controlled Release Society (SPLC-CRS) Member

Conference scientific committee

Conference name Conference host
2021/11/30 - 2021/11/30 i3S – Instituto de Investigação e Inovação em Saúde
2021/01/21 - 2021/01/21 3rd SPLC-CRS Young Scientists Virtual Meeting CRS Spanish Portuguese Local Chapter
2019/06/27 - 2019/06/28 Interrogations at the Biointerface – 7th Advanced Summer School: “Do organoids fill the in vitro/in vivo gap?” Biblioteca Almeida Garret, Porto, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023 - Current Pharmaceutical Technology (Mestrado integrado) Instituto Universitário de Ciências da Saúde, Portugal
2020 - Current Bromatology I Ciências da Nutrição (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - Current Bromatology II Ciências da Nutrição (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - Current Food Biotechnology Ciências da Nutrição (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2022/02 - 2023 Instrumental Methods of Analysis Ciências Farmacêuticas (Mestrado integrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2022 - 2023 Toxicology and Toxicological Analysis Ciências Farmacêuticas (Mestrado integrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2022/02 - 2022/06 Bromatology and Bromatological Analysis Ciências Farmacêuticas (Mestrado integrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2021 - 2022 Instrumental Methods of Analysis Ciências Biomédicas (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2021 - 2022 Instrumental Methods of Analysis Ciências Laboratoriais Forenses (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2018 - 2018 Course Lecturer (10h). Advanced Course in Nanotechnology, Drug Delivery and Drug Targeting, Instituto Universitário de Ciências da Saúde/CESPU, September 20-28, 2018. Doutoramento em Ciências Biológicas Aplicadas à Saúde Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2016 - 2016 Course Lecturer (7h). Advanced Course in Nanotechnology, Drug Delivery and Drug Targeting, Instituto Universitário de Ciências da Saúde/CESPU, September 27- October 4, 2016. Doutoramento em Ciências Biológicas Aplicadas à Saúde Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2020 - Current Abstracts Evaluation pannel for Controlled Released Society Annual Meeting & Exposition, 27th June-1st July, Las Vegas, Nevada, USA.
Evaluator
2021/11/30 - 2021/11/30 4th PhDay: Break borders and build opportunities
Evaluator
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/01/21 - 2021/01/21 3rd SPLC-CRS Young Scientists Virtual Meeting
Evaluator

Journal scientific committee

Journal title (ISSN) Publisher
2020 - Current Journal of Controlled Release (https://www.journals) Elsevier
2019 - Current Journal of Drug Delivery Science and Technology (1773-2247) Elsevier
2019 - Current Drug Delivery and Translational Research (2190-3948) Springer
2015 - Current Advanced Drug Delivery Reviews (0169-409X) Elsevier
Distinctions

Award

2018 HIVR4P Scholarship
International AIDS Society, Switzerland
2013 FCT PhD fellowship (SFRH/BD/96519/2013) )
Fundação para a Ciência e a Tecnologia, Portugal