| Journal article |
- Muege Yalcin; Deeksha Malhan; Alireza Basti; Ana Rita Peralta; Joaquim J. Ferreira; Angela Relógio. "A Computational Analysis
in a Cohort of Parkinson’s Disease Patients and Clock-Modified Colorectal Cancer Cells Reveals Common Expression Alterations
in Clock-Regulated Genes". Cancers (2021): https://www.mdpi.com/2072-6694/13/23/5978.
10.3390/cancers13235978
- "A mathematical model of the circadian clock and drug pharmacology to optimize irinotecan administration timing in colorectal
cancer.". Computational and structural biotechnology journal (2021): https://europepmc.org/articles/PMC8477139.
10.1016/j.csbj.2021.08.051
- Basti, A.; Yalçin, M.; Herms, D.; Hesse, J.; Aboumanify, O.; Li, Y.; Aretz, Z.; et al. "Diurnal variations in the expression
of core-clock genes correlate with resting muscle properties and predict fluctuations in exercise performance across the day".
BMJ Open Sport and Exercise Medicine 7 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85100968590&partnerID=MN8TOARS.
10.1136/bmjsem-2020-000876
- Gaspar, L.S.; Hesse, J.; Yalçin, M.; Santos, B.; Carvalhas-Almeida, C.; Ferreira, M.; Moita, J.; et al. "Long-term continuous
positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea". EBioMedicine
65 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85101588732&partnerID=MN8TOARS.
10.1016/j.ebiom.2021.103248
- Furtado A; Astaburuaga R; Costa A; Duarte AC; Gonçalves I; Cipolla-Neto J; Lemos MC; et al. "The Rhythmicity of Clock Genes
is Disrupted in the Choroid Plexus of the APP/PS1 Mouse Model of Alzheimer's Disease.". Journal of Alzheimer's disease
: JAD (2020): http://europepmc.org/abstract/med/32741824.
10.3233/jad-200331
- Alireza Basti; Rita Fior; Müge Yal¿in; Vanda Póvoa; Rosario Astaburuaga; Yin Li; Julian Naderi; Miguel Godinho Ferreira; Angela
Relógio. "The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in A Zebrafish Xenograft Colon
Cancer Model". Cancers (2020): https://www.mdpi.com/2072-6694/12/4/853.
10.3390/cancers12040853
- Müge Yalçin; Rukeia El-Athman; Koliane Ouk; Josef Priller; Angela Relógio. "Analysis of the Circadian Regulation of Cancer
Hallmarks by a Cross-Platform Study of Colorectal Cancer Time-Series Data Reveals an Association with Genes Involved in Huntington’s
Disease". Cancers (2020): https://www.mdpi.com/2072-6694/12/4/963.
10.3390/cancers12040963
- Furtado, A.; Astaburuaga, R.; Costa, A.; Duarte, A.C.; Goncalves, I.; Cipolla-Neto, J.; Lemos, M.C.; et al. "The Rhythmicity
of Clock Genes is Disrupted in the Choroid Plexus of the APP/PS1 Mouse Model of Alzheimer's Disease". Journal of Alzheimer's
Disease 77 2 (2020): 795-806. http://www.scopus.com/inward/record.url?eid=2-s2.0-85091469905&partnerID=MN8TOARS.
10.3233/JAD-200331
- Hesse, J.; Malhan, D.; Yalçin, M.; Aboumanify, O.; Basti, A.; Relógio, A.. "An optimal time for treatment-predicting circadian
time by machine learning and mathematical modelling". Cancers 12 11 (2020): 1-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-85094207246&partnerID=MN8TOARS.
10.3390/cancers12113103
- Li, Y.; Basti, A.; Yalçin, M.; Relógio, A.. "Circadian Dysregulation of the TGFß/SMAD4 Pathway Modulates Metastatic Properties
and Cell Fate Decisions in Pancreatic Cancer Cells". iScience 23 10 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85091571655&partnerID=MN8TOARS.
10.1016/j.isci.2020.101551
- Parascandolo, A.; Bonavita, R.; Astaburuaga, R.; Sciuto, A.; Reggio, S.; Barra, E.; Corcione, F.; et al. "Effect of naive
and cancer-educated fibroblasts on colon cancer cell circadian growth rhythm". Cell Death and Disease 11 4 (2020):
http://www.scopus.com/inward/record.url?eid=2-s2.0-85083972242&partnerID=MN8TOARS.
10.1038/s41419-020-2468-2
- Mazzoccoli, G.; Vinciguerra, M.; Carbone, A.; Relógio, A.. "The circadian clock, the immune system, and viral infections:
The intricate relationship between biological time and host-virus interaction". Pathogens 9 2 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078985992&partnerID=MN8TOARS.
10.3390/pathogens9020083
- Rosario Astaburuaga; Orlando Daniel Quintanar Haro; Tobias Stauber; Angela Relógio. "A Mathematical Model of Lysosomal Ion
Homeostasis Points to Differential Effects of Cl- Transport in Ca2+ Dynamics". Cells (2019):
https://www.mdpi.com/2073-4409/8/10/1263.
10.3390/cells8101263
- Nikolai Genov; Stefano Castellana; Felix Scholkmann; Daniele Capocefalo; Mauro Truglio; Jessica Diana Rosati; Elisa Maria
Turco; et al. "A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics". International Journal
of Molecular Sciences (2019): https://www.mdpi.com/1422-0067/20/18/4585.
10.3390/ijms20184585
- El-Athman R; Knezevic D; Fuhr L; Relógio A. "A Computational Analysis of Alternative Splicing across Mammalian Tissues Reveals
Circadian and Ultradian Rhythms in Splicing Events.". International journal of molecular sciences (2019): http://europepmc.org/abstract/med/31443305.
10.3390/ijms20163977
- Relógio, Angela. "The Interplay between Colon Cancer Cells and Tumour-Associated Stromal Cells Impacts the Biological Clock
and Enhances Malignant Phenotypes". Cancers (2019): http://dx.doi.org/10.3390/cancers11070988.
10.3390/cancers11070988
- Relógio, Angela. "The importance of determining circadian parameters in pharmacological studies.". British journal of pharmacology
(2019): https://doi.org/10.1111/bph.14712.
10.1111/bph.14712
- Genov N; Basti A; Abreu M; Relógio A. "Temporal Splicing Switches in Elements of the TNF-Pathway Identified by Computational
Analysis of Transcriptome Data for Human Cell Lines.". International journal of molecular sciences (2019): http://europepmc.org/abstract/med/30857150.
10.3390/ijms20051182
- Astaburuaga, R.; Basti, A.; Li, Y.; Herms, D.; Relógio, A.. "Circadian regulation of physiology: Relevance for space medicine".
REACH 14-15 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85068511097&partnerID=MN8TOARS.
10.1016/j.reach.2019.100029
- Genov, N.; Basti, A.; Abreu, M.; Astaburuaga, R.; Relógio, A.. "A bioinformatic analysis identifies circadian expression of
splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line". Scientific Reports 9 1 (2019):
http://www.scopus.com/inward/record.url?eid=2-s2.0-85069964626&partnerID=MN8TOARS.
10.1038/s41598-019-47343-w
- Fuhr, L.; El-Athman, R.; Scrima, R.; Cela, O.; Carbone, A.; Knoop, H.; Li, Y.; et al. "The Circadian Clock Regulates Metabolic
Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer". EBioMedicine
33 (2018): 105-121. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049588993&partnerID=MN8TOARS.
10.1016/j.ebiom.2018.07.002
- Abreu, M.; Basti, A.; Genov, N.; Mazzoccoli, G.; Relógio, A.. "The reciprocal interplay between TNFa and the circadian clock
impacts on cell proliferation and migration in Hodgkin lymphoma cells". Scientific Reports 8 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85050947899&partnerID=MN8TOARS.
10.1038/s41598-018-29847-z
- El-Athman, R.; Fuhr, L.; Relógio, A.. "A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer".
EBioMedicine 33 (2018): 68-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048933315&partnerID=MN8TOARS.
10.1016/j.ebiom.2018.06.012
- Castellana, S.; Mazza, T.; Capocefalo, D.; Genov, N.; Biagini, T.; Fusilli, C.; Scholkmann, F.; et al. "Systematic analysis
of mouse genome reveals distinct evolutionary and functional properties among circadian and ultradian genes". Frontiers
in Physiology 9 AUG (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85052054046&partnerID=MN8TOARS.
10.3389/fphys.2018.01178
- El-Athman, R.; Relógio, A.. "Escaping Circadian Regulation: An Emerging Hallmark of Cancer?". Cell Systems (2018):
http://www.scopus.com/inward/record.url?eid=2-s2.0-85044139127&partnerID=MN8TOARS.
10.1016/j.cels.2018.03.006
- Relógio, Angela. "The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.". PLOS Biology
(2017): https://www.ncbi.nlm.nih.gov/pubmed/29216180.
10.1371/journal.pbio.2002940
- Scrima, R.; Cela, O.; Merla, G.; Augello, B.; Rubino, R.; Quarato, G.; Fugetto, S.; et al. "Clock-genes and mitochondrial
respiratory activity: Evidence of a reciprocal interplay". Biochimica et Biophysica Acta - Bioenergetics 1857 8 (2016):
1344-1351. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963579212&partnerID=MN8TOARS.
10.1016/j.bbabio.2016.03.035
- Cela O; Scrima R; Pazienza V; Merla G; Benegiamo G; Augello B; Fugetto S; et al. "Clock genes-dependent acetylation of complex
I sets rhythmic activity of mitochondrial OxPhos.". (2016): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000371940500009&KeyUID=WOS:000371940500009.
10.1016/j.bbamcr.2015.12.018
- Lehmann R; Childs L; Thomas P; Abreu M; Fuhr L; Herzel H; Leser U; Relógio A. "Assembly of a comprehensive regulatory network
for the mammalian circadian clock: a bioinformatics approach.". (2015): http://europepmc.org/abstract/med/25945798.
10.1371/journal.pone.0126283
- Fuhr L; Abreu M; Pett P; Relógio A. "Circadian systems biology: When time matters.". (2015): http://europepmc.org/abstract/med/26288701.
10.1016/j.csbj.2015.07.001
- Abreu, M. T.; Relogio, A.. "Circadian regulation of the immune system: a role in tumourigenesis". Febs Journal 282
(2015): 184-185. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362570603084&KeyUID=WOS:000362570603084.
- Fuhr, L.; Relogio, A.. "Analysis and identification of circadian-regulated metabolic pathways in tumourigenesis". Febs
Journal 282 (2015): 184-184. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362570603082&KeyUID=WOS:000362570603082.
- Relogio, A.. "Deregulation of circadian time and its correlation with tumour progression". Febs Journal 282 (2015):
14-14. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362570600035&KeyUID=WOS:000362570600035.
- Relógio A; Thomas P; Medina-Pérez P; Reischl S; Bervoets S; Gloc E; Riemer P; et al. "Ras-mediated deregulation of the circadian
clock in cancer.". (2014): http://europepmc.org/abstract/med/24875049.
10.1371/journal.pgen.1004338
- Relogio, A.; Westermark, P. O.; Wallach, T.; Schellenberg, K.; Kramer, A.; Herzel, H.. "Tuning the Mammalian Circadian Clock:
Robust Synergy of Two Loops". Plos Computational Biology 7 12 (2011): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000299167800029&KeyUID=WOS:000299167800029.
10.1371/journal.pcbi.1002309
- Bozek K; Relógio A; Kielbasa SM; Heine M; Dame C; Kramer A; Herzel H. "Regulation of clock-controlled genes in mammals.".
(2009): http://europepmc.org/abstract/med/19287494.
10.1371/journal.pone.0004882
- Meister, S.; Agianian, B.; Turlure, F.; Relogio, A.; Morlais, I.; Kafatos, F. C.; Christophides, G. K.. "Anopheles gambiae
PGRPLC-Mediated Defense against Bacteria Modulates Infections with Malaria Parasites". Plos Pathogens 5 8 (2009): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000270804500027&KeyUID=WOS:000270804500027.
10.1371/journal.ppat.1000542
- Relógio A; Ben-Dov C; Baum M; Ruggiu M; Gemund C; Benes V; Darnell RB; Valcárcel J. "Alternative splicing microarrays reveal
functional expression of neuron-specific regulators in Hodgkin lymphoma cells.". (2005): http://europepmc.org/abstract/med/15546866.
10.1074/jbc.M411976200
- Relógio A; Schwager C; Richter A; Ansorge W; Valcárcel J; Relógio, A.; Schwager, C.; et al. "Optimization of oligonucleotide-based
DNA microarrays.". Nucleic acids research 30 11 (2002): http://europepmc.org/abstract/med/12034852.
10.1093/nar/30.11.e51
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