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Pedro M. Matias graduated (Licenciatura) in Chemical Engineering (Chemistry and Processes) in 1983 at the Instituto Superior Técnico of the University of Lisbon and obtained a PhD in Crystallography in 1986 at the University of Pittsburgh (USA). He is presently a career Principal Investigator at the ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier of the NOVA University of Lisbon, coordinator of the Biological Chemistry Division and member of the Scientific Council of ITQB NOVA. He is also a member of the Research Unit MOSTMICRO-ITQB, the Associated Laboratory LS4FUTURE and director of the Structural Biology for Drug Development at iBET - Instituto de Biologia Experimental e Tecnológica. He has published to date 103 papers in international peer-reviewed journals and 4 book chapters. He organized 5 National and International Scientific events, supervised 1 PhD thesis and co-supervised 6. He also co-supervised 2 MSc dissertations. His professional activities involved interactions with more than 385 collaborators in the co-authorship of scientific works.
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Identification

Personal identification

Full name
Pedro Manuel Henriques Marques Matias

Citation names

  • Matias, Pedro M

Author identifiers

Ciência ID
781D-CE99-A983
ORCID iD
0000-0001-6170-451X
Scopus Author Id
6603792037

Addresses

  • Instituto de Tecnologia Química e Biológica. Apartado 127, 2781-901, OEIRAS, Oeiras, Portugal (Professional)

Websites

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
1983/09 - 1986/11
Concluded
 Ph.D. in Crystallography (Doctor of Philosophy)
University of Pittsburgh, PA 15260, EUA, United States
""X-ray and Neutron Diffraction Studies of Small Organic Molecules: Deuterionitromethane, Ethylene Carbonate, Isopropyl 1-S-beta-D-Galactopyrano-side monohydrate and Diacetamide (cis-trans )"" (THESIS/DISSERTATION)
 Approved
1977/10 - 1983/06
Concluded
 Chemical Engineering - Chemistry and Processes (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (THESIS/DISSERTATION)
 17
Affiliation

Science

Category
Host institution 		Employer
2015 - Current Principal Investigator (Research) Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal
2008/03/11 - Current Principal Investigator (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
1995/11/02 - 2008/03/10 Auxiliary Researcher (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
1992/11/02 - 1995/11/01 Research Assistant (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2014 - Current Associate Professor (University Teacher) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
1990/01/01 - 1992/11/01 Assistant Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal

Positions / Appointments

Category
Host institution 		Employer
2024/03 - Current Coordinator of the Macromolecular Crystallography Unit Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022 - Current Member of the Institute Council of ITQB NOVA Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015 - Current Member of the Directive Board Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal
2016 - 2022 Member of the Scientific Council of ITQB NOVA Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016 - 2022 Coordinator of the Biological Chemistry Division Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Others

Category
Host institution 		Employer
2008/01/01 - 2023/04/30 Head of the Unit Structural Biology for Drug Development Instituto de Biologia Experimental e Tecnológica, Portugal
Projects

Grant

Designation Funders
2019/09/01 - 2023/02/28 IMpaCT - Imaging life from Molecules to cells - building knowledge on Cryo-electron microscopy methodologies at ITQB NOVA
857203
Principal investigator
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 European Research Executive Agency
Concluded
2016/01 - 2018/12 Engineering a highly active NiFeSe Hydrogenase for electrocatalytic and photocatalytic applications
Provided by PTCRIS: 141512
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
2016/01 - 2018/12 Structure and Function of a Dodecameric Molecular Machine: the human RuvBL1/RuvBL2 Complex and its Role in Disease
grant.Provided by PTCRIS: 140088
Researcher
Fundação para a Ciência e a Tecnologia
2013/06 - 2015/05 Structural and functional insights into centriole biogenesis
127024
Provided by PTCRIS: 127024
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2013/03 - 2015/03 Structural Determinants of Oxygen Tolerance in a NiFeSe Hydrogenase
125671
Provided by PTCRIS: 125671
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
2011/03 - 2014/08 Structural determinants of superoxide reduction - A detoxification system essential for life
Provided by PTCRIS: 111940
111940
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2010/01 - 2013/06 Engineering mini Superoxide Dismutases with tunable redox properties
98406
Provided by PTCRIS: 98406
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2010/02 - 2013/02 Mind the gap: How extracellular respiration is linked across the periplasmic space to the cytoplasmic oxidation of substrates. A key step in bioenergy harvesting.
98158
Provided by PTCRIS: 98158
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2011/09 Towards biohydrogen production - study of a high-activity, oxygen-resistant bacterial hydrogenase
Provided by PTCRIS: 70429
70429
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2011/06 Molecular Adaptation to Extreme Environments: Structural Studies of Proteins Involved in the Synthesis of Osmolytes in (hyper)thermophylic micro-organisms
71142
Provided by PTCRIS: 71142
Principal investigator
Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2011/03 Iron Metabolism Study in Deinococcus radiodurans- Novel strategies
Provided by PTCRIS: 67240
67240
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2008/02 - 2011/01 Iron metabolism in sulphate reducing bacteria
Provided by PTCRIS: 67107
67107
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2009/12 A structural genomics approach to membrane transport proteins from Archaea
66833
Provided by PTCRIS: 66833
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
Outputs

Publications

Book
  1. Devos, A. M.; Tong, L.; Milburn, M. V.; Matias, P. M.; Kim, S. H.. 3-DIMENSIONAL STRUCTURE OF RAS P21 PROTEINS. 1989.
Book chapter
  1. Alves, Paula M; Matias, Pedro M; Roque, ACA. "SMALL MOLECULES DRUGS AND BIOPHARMACEUTICALS". In From Life Molecules to Global Health, edited by Fragata, José. Cascais, Portugal: Principia, 2022.
    Published
  2. Zacarias, Sónia; Vélez, Marisela; Pita, Marcos; De Lacey, Antonio L.; Matias, Pedro M.; Pereira, Inês A.C.. "Characterization of the [NiFeSe] hydrogenase from Desulfovibrio vulgaris Hildenborough". In Enzymes of Energy Technology, 169-201. Elsevier, 2018.
    10.1016/bs.mie.2018.10.003
  3. Romão, Célia V.; Archer, Margarida; Lobo, Susana A.; Louro, Ricardo O.; Pereira, Inês A. C.; Saraiva, Lígia M.; Teixeira, Miguel; Matias, Pedro M.. "89 Diversity of Heme Proteins in Sulfate Reducing Bacteria". In Handbook of Porphyrin Science (Volume 19), 139-229. World Scientific Publishing Company, 2012.
    10.1142/9789814335508_0016
  4. Sabine Gorynia; Bandeiras, Tiago M.; Matias, Pedro M; Pinho, Filipa G.; McVey, Colin E.; Donner, P.; Carrondo, M.A.; et al. "RuvBL1 and RuvBL2 and Their Complex Proteins Implicated in Many Cellular Pathways". In Macromolecular Crystallography, edited by Carrondo, M.A.; Spadon, P., 55-63. Dordrecht, Netherlands: Springer, 2012.
    Published • 10.1007/978-94-007-2530-0_5
  5. de Vos, A. M.; Tong, L.; Milburn, M. V.; Matias, P. M.; Kim, S.-H.. "Three-Dimensional Structure of ras p21 Proteins". In The Guanine — Nucleotide Binding Proteins, 27-34. Springer US, 1989.
    10.1007/978-1-4757-2037-2_3
Encyclopedia entry
  1. Carrondo, Maria Arménia ; Soares, Claudio M.; Matias, Pedro M. "Nine-Heme Cytochrome c". In Handbook of Metalloproteins, edited by Messerschmidt, Albrecht; Huber, Robert; Poulos, Thomas; Wieghardt, Karl. John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/0470028637.met112.
    Published • 10.1002/0470028637.met112
Journal article
  1. Salgueiro, Bruno A.; Saramago, Margarida; Tully, Mark D.; Issoglio, Federico; Silva, Sara T. N.; Paiva, Ana C. F.; Arraiano, Cecília M.; et al. "SARS-CoV2 Nsp1 is a metal-dependent DNA and RNA endonuclease". BioMetals (2024): http://dx.doi.org/10.1007/s10534-024-00596-z.
    10.1007/s10534-024-00596-z
  2. Fernandes, Andreia; Williamson, Adele; Matias, Pedro M.; Moe, Elin. "Structure/function studies of the NAD+-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding". Extremophiles 27 3 (2023): http://dx.doi.org/10.1007/s00792-023-01309-z.
    Open access • Published • 10.1007/s00792-023-01309-z
  3. Gouveia, André G.; Salgueiro, Bruno A.; Ranmar, Dean O.; Antunes, Wilson D. T.; Kirchweger, Peter; Golani, Ofra; Wolf, Sharon G.; et al. "Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus". Frontiers in Microbiology 14 (2023): http://dx.doi.org/10.3389/fmicb.2023.1240798.
    Open access • Published • 10.3389/fmicb.2023.1240798
  4. Liliana S.O. Silva; Pedro M. Matias; Celia V. Romão; Saraiva LM. "Structural Basis of RICs Iron Donation for Iron-Sulfur Cluster Biogenesis". Frontiers in Microbiology 12 (2021): https://novaresearch.unl.pt/en/publications/5601cd4d-7f65-4776-bc06-392bf3789624.
    10.3389/fmicb.2021.670681
  5. Sónia Zacarias; Adriana Temporão; Philippe Carpentier; Peter van der Linden; Inês A. C. Pereira; Pedro M. Matias. "Exploring the gas access routes in a [NiFeSe] hydrogenase using crystals pressurized with krypton and oxygen". JBIC Journal of Biological Inorganic Chemistry (2020): https://doi.org/10.1007/s00775-020-01814-y.
    10.1007/s00775-020-01814-y
  6. Sousa, Bárbara B.; Sousa, Marcos F. Q.; Marques, Marta C.; Seixas, João D.; Brito, José A.; Matias, Pedro M.; Bernardes, Gonçalo J. L.; Roldão, António. "A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening". Bioprocess and Biosystems Engineering (2020): http://dx.doi.org/10.1007/s00449-020-02421-6.
    10.1007/s00449-020-02421-6
  7. Adrian Ruff; Julian Szczesny; Maria Vega; Sonia Zacarias; Pedro M. Matias; Sébastien Gounel; Nicolas Mano; Inês A. C. Pereira; Wolfgang Schuhmann. "Redox-Polymer-Wired [NiFeSe] Hydrogenase Variants with Enhanced O 2 Stability for Triple-Protected High-Current-Density H 2 -Oxidation Bioanodes". ChemSusChem 13 14 (2020): 3627-3635. https://doi.org/10.1002/cssc.202000999.
    10.1002/cssc.202000999
  8. Seixas, João D.; Sousa, Bárbara B.; Marques, Marta C.; Guerreiro, Ana; Traquete, Rui; Rodrigues, Tiago; Albuquerque, Inês S.; et al. "Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors". RSC Chemical Biology 1 4 (2020): 251-262. http://dx.doi.org/10.1039/d0cb00033g.
    10.1039/d0cb00033g
  9. Sónia Zacarias; Adriana Temporão; Melisa del Barrio; Vincent Fourmond; Christophe Léger; Pedro M. Matias; Inês A. C. Pereira. "A Hydrophilic Channel Is Involved in Oxidative Inactivation of a [NiFeSe] Hydrogenase". ACS Catalysis (2019): 8509-8519. https://doi.org/10.1021/acscatal.9b02347.
    10.1021/acscatal.9b02347
  10. Bruno M Fonseca; Luis Silva; Ines B. Trindade; Elin Moe; Pedro M. Matias; Ricardo Louro; Catarina M. Paquete. "Optimizing Electroactive Organisms: The Effect of Orthologous Proteins". FRONTIERS IN ENERGY RESEARCH 7 (2019): https://novaresearch.unl.pt/en/publications/7aa7ddfc-7cff-4983-bd58-a073df855242.
    10.3389/fenrg.2019.00002
  11. Inês B. Trindade; José M. Silva; Bruno M Fonseca; Teresa Catarino; Masaki Fujita; Pedro M. Matias; Elin Moe; et al. "Structure and reactivity of a siderophore-interacting protein from the marine bacterium Shewanella reveals unanticipated functional versatility". Journal of Biological Chemistry 294 1 (2019): 157-167. https://novaresearch.unl.pt/en/publications/2edefe48-6a7f-4347-bef9-15f45041b387.
    10.1074/jbc.RA118.005041
  12. Sara T. N. Silva; José A. Brito; Rocío Arranz; Carlos Óscar S. Sorzano; Christine Ebel; James Doutch; Mark D. Tully; et al. "X-ray structure of full-length human RuvB-Like 2 – mechanistic insights into coupling between ATP binding and mechanical action". Scientific Reports (2018): https://doi.org/10.1038/s41598-018-31997-z.
    10.1038/s41598-018-31997-z
  13. Romão, Célia V.; Matias, Pedro M.; Sousa, Cristiana M.; Pinho, Filipa G.; Pinto, Ana F.; Teixeira, Miguel; Bandeiras, Tiago M.. "Insights into the Structures of Superoxide Reductases from the Symbionts Ignicoccus hospitalis and Nanoarchaeum equitans". Biochemistry 57 36 (2018): 5271-5281. http://dx.doi.org/10.1021/acs.biochem.8b00334.
    10.1021/acs.biochem.8b00334
  14. Lobo, S.A.L.; Videira, M.A.M.; Pacheco, I.; Wass, M.N.; Warren, M.J.; Teixeira, M.; Matias, P.M.; Romão, C.V.; Saraiva, L.M.. "Desulfovibrio vulgaris CbiKPcobaltochelatase: evolution of a haem binding protein orchestrated by the incorporation of two histidine residues". Environmental Microbiology 19 1 (2017): 106-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983433234&partnerID=MN8TOARS.
    10.1111/1462-2920.13479
  15. Marques, M.C.; Tapia, C.; Gutiérrez-Sanz, O.; Ramos, A.R.; Keller, K.L.; Wall, J.D.; De Lacey, A.L.; Matias, P.M.; Pereira, I.A.C.. "The direct role of selenocysteine in [NiFeSe] hydrogenase maturation and catalysis". Nature Chemical Biology 13 5 (2017): 544-550. http://www.scopus.com/inward/record.url?eid=2-s2.0-85015672149&partnerID=MN8TOARS.
    10.1038/nchembio.2335
  16. Amaral, M.; Kokh, D.B.; Bomke, J.; Wegener, A.; Buchstaller, H.P.; Eggenweiler, H.M.; Matias, P.; et al. "Protein conformational flexibility modulates kinetics and thermodynamics of drug binding". Nature Communications 8 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85039455347&partnerID=MN8TOARS.
    10.1038/s41467-017-02258-w
  17. Clarke, T.L.; Sanchez-Bailon, M.P.; Chiang, K.; Reynolds, J.J.; Herrero-Ruiz, J.; Bandeiras, T.M.; Matias, P.M.; et al. "PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination". Molecular Cell 65 5 (2017): 900-916.e7. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013633978&partnerID=MN8TOARS.
    10.1016/j.molcel.2017.01.019
  18. Colaço, H.G.; Santo, P.E.; Matias, P.M.; Bandeiras, T.M.; Vicente, J.B.. "Roles of Escherichia coli ZinT in cobalt, mercury and cadmium resistance and structural insights into the metal binding mechanism". Metallomics 8 3 (2016): 327-336. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961244965&partnerID=MN8TOARS.
    10.1039/c5mt00291e
  19. Trindade, I.B.; Fonseca, B.M.; Matias, P.M.; Louro, R.O.; Moe, E.. "A putative siderophore-interacting protein from the marine bacterium Shewanella frigidimarina NCIMB 400: Cloning, expression, purification, crystallization and X-ray diffraction analysis". Acta Crystallographica Section:F Structural Biology Communications 72 (2016): 667-671. http://www.scopus.com/inward/record.url?eid=2-s2.0-84986325474&partnerID=MN8TOARS.
    10.1107/S2053230X16011419
  20. Sousa, C.M.; Carpentier, P.; Matias, P.M.; Testa, F.; Pinho, F.; Sarti, P.; Giuffrè, A.; Bandeiras, T.M.; Romão, C.V.. "Superoxide reductase from Giardia intestinalis: Structural characterization of the first SOR from a eukaryotic organism shows an iron centre that is highly sensitive to photoreduction". Acta Crystallographica Section D: Biological Crystallography 71 (2015): 2236-2247. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946606061&partnerID=MN8TOARS.
    10.1107/S1399004715015825
  21. Zaarur, N.; Xu, X.; Lestienne, P.; Meriin, A.B.; McComb, M.; Costello, C.E.; Newnam, G.P.; et al. "RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils". EMBO Journal 34 18 (2015): 2363-2382. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941732990&partnerID=MN8TOARS.
    10.15252/embj.201591245
  22. Matias, P.M.; Baek, S.H.; Bandeiras, T.M.; Dutta, A.; Houry, W.A.; Llorca, O.; Rosenbaum, J.. "The AAA+ proteins Pontin and Reptin enter adult age: From understanding their basic biology to the identification of selective inhibitors". Frontiers in Molecular Biosciences 2 MAY (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84956964981&partnerID=MN8TOARS.
    10.3389/fmolb.2015.00017
  23. Leite, J.P.; Duarte, M.; Paiva, A.M.; Ferreira-Da-Silva, F.; Matias, P.M.; Nunes, O.C.; Gales, L.. "Structure-guided engineering of molinate hydrolase for the degradation of thiocarbamate pesticides". PLoS ONE 10 4 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84929379140&partnerID=MN8TOARS.
    10.1371/journal.pone.0123430
  24. Miller, S.P.; Gonçalves, S.; Matias, P.M.; Dean, A.M.. "Evolution of a transition state: Role of lys100 in the active site of isocitrate dehydrogenase". ChemBioChem 15 8 (2014): 1145-1153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901378768&partnerID=MN8TOARS.
    10.1002/cbic.201400040
  25. Borges, N.; Jorge, C.D.; Gonçalves, L.G.; Gonçalves, S.; Matias, P.M.; Santos, H.. "Mannosylglycerate: structural analysis of biosynthesis and evolutionary history". Extremophiles 18 5 (2014): 835-852. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929510245&partnerID=MN8TOARS.
    10.1007/s00792-014-0661-x
  26. Nogly, P.; Matias, P.M.; De Rosa, M.; Castro, R.; Santos, H.; Neves, A.R.; Archer, M.. "High-resolution structure of an atypical -phosphoglucomutase related to eukaryotic phosphomannomutases". Acta Crystallographica Section D: Biological Crystallography 69 10 (2013): 2008-2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885458762&partnerID=MN8TOARS.
    10.1107/S0907444913017046
  27. Rosenbaum, J.; Baek, S.H.; Dutta, A.; Houry, W.A.; Huber, O.; Hupp, T.R.; Matias, P.M.. "The emergence of the conserved AAA+ ATPases pontin and reptin on the signaling landscape". Science Signaling 6 266 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875204484&partnerID=MN8TOARS.
    10.1126/scisignal.2003906
  28. Marques, M.C.; Coelho, R.; Pereira, I.A.C.; Matias, P.M.. "Redox state-dependent changes in the crystal structure of [NiFeSe] hydrogenase from Desulfovibrio vulgaris Hildenborough". International Journal of Hydrogen Energy 38 21 (2013): 8664-8682. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879903914&partnerID=MN8TOARS.
    10.1016/j.ijhydene.2013.04.132
  29. Gonçalves, S.; Miller, S.P.; Carrondo, M.A.; Dean, A.M.; Matias, P.M.. "Induced fit and the catalytic mechanism of isocitrate dehydrogenase". Biochemistry 51 36 (2012): 7098-7115. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866068233&partnerID=MN8TOARS.
    10.1021/bi300483w
  30. Gonçalves, S.; Esteves, A.M.; Santos, H.; Borges, N.; Matias, P.M.. "Three-dimensional structure of mannosyl-3-phosphoglycerate phosphatase from thermus thermophilus HB27: A new member of the haloalcanoic acid dehalogenase superfamily". Biochemistry 50 44 (2011): 9551-9567. http://www.scopus.com/inward/record.url?eid=2-s2.0-80155206893&partnerID=MN8TOARS.
    10.1021/bi201171h
  31. Gorynia, S.; Bandeiras, T.M.; Pinho, F.G.; McVey, C.E.; Vonrhein, C.; Round, A.; Svergun, D.I.; et al. "Structural and functional insights into a dodecameric molecular machine - The RuvBL1/RuvBL2 complex". Journal of Structural Biology 176 3 (2011): 279-291. http://www.scopus.com/inward/record.url?eid=2-s2.0-80455176998&partnerID=MN8TOARS.
    10.1016/j.jsb.2011.09.001
  32. Baltazar, C.S.A.; Marques, M.C.; Soares, C.M.; DeLacey, A.M.; Pereira, I.A.C.; Matias, P.M.. "Nickel-iron-selenium hydrogenases - An overview". European Journal of Inorganic Chemistry 7 (2011): 948-962. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951883377&partnerID=MN8TOARS.
    10.1002/ejic.201001127
  33. Pinho, F.G.; Pinto, A.F.; Pinto, L.C.; Huber, H.; Romão, C.V.; Teixeira, M.; Matias, P.M.; Bandeiras, T.M.. "Superoxide reductase from Nanoarchaeum equitans: Expression, purification, crystallization and preliminary X-ray crystallographic analysis". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 67 5 (2011): 591-595. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955667521&partnerID=MN8TOARS.
    10.1107/S1744309111009432
  34. Romão, C.V.; Ladakis, D.; Lobo, S.A.L.; Carrondo, M.A.; Brindley, A.A.; Deery, E.; Matias, P.M.; et al. "Evolution in a family of chelatases facilitated by the introduction of active site asymmetry and protein oligomerization". Proceedings of the National Academy of Sciences of the United States of America 108 1 (2011): 97-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651075909&partnerID=MN8TOARS.
    10.1073/pnas.1014298108
  35. Gonçalves, S.; Esteves, A.M.; Borges, N.; Santos, H.; Matias, P.M.; Pedro M. Matias; Helena Santos; Nuno Borges. "Crystallization and preliminary X-ray analysis of mannosyl-3- phosphoglycerate phosphatase from Thermus thermophilus HB27". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 67 3 (2011): 390-396. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952692197&partnerID=MN8TOARS.
    10.1107/S1744309111002843
  36. Miguel Teixeira; Saraiva LM; Pedro M. Matias; Pinho, F.G.; Romão, C.V.; Pinto, A.F.; Saraiva, L.M.; et al. "Cloning, purification, crystallization and X-ray crystallographic analysis of Ignicoccus hospitalis neelaredoxin". Acta Crystallographica Section F-Structural Biology And Crystallization Com 66 Part 5 (2010): 605-607. https://novaresearch.unl.pt/en/publications/0b08acbf-5bb1-4ffd-8b11-4d52f3fd19cb.
    10.1107/s1744309110012030
  37. Gonçalves, S.; Borges, N.; Esteves, A.M.; Victor, B.L.; Soares, C.M.; Santos, H.; Matias, P.M.. "Structural analysis of Thermus thermophilus HB27 mannosyl-3- phosphoglycerate synthase provides evidence for a second catalytic metal ion and new insight into the retaining mechanism of glycosyltransferases". Journal of Biological Chemistry 285 23 (2010): 17857-17868. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952938697&partnerID=MN8TOARS.
    10.1074/jbc.M109.095976
  38. Marques, M.C.; Coelho, R.; De Lacey, A.L.; Pereira, I.A.C.; Matias, P.M.. "The three-dimensional structure of [nifese] hydrogenase from desulfovibrio vulgaris hildenborough: A hydrogenase without a bridging ligand in the active site in its oxidised, "as-isolated" state". Journal of Molecular Biology 396 4 (2010): 893-907. http://www.scopus.com/inward/record.url?eid=2-s2.0-77649271875&partnerID=MN8TOARS.
    10.1016/j.jmb.2009.12.013
  39. Bandeiras, T.M.; Romão, C.V.; Rodrigues, J.V.; Teixeira, M.; Matias, P.M.; Pedro M. Matias; Tiago Miguel Bandeiras; Miguel Teixeira. "Purification, crystallization and X-ray crystallographic analysis of Archaeoglobus fulgidus neelaredoxin". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 66 3 (2010): 316-319. http://www.scopus.com/inward/record.url?eid=2-s2.0-77749273980&partnerID=MN8TOARS.
    10.1107/S1744309110000916
  40. Crowley, P.B.; Matias, P.M.; Khan, A.R.; Roessle, M.; Svergun, D.I.. "Metal-mediated self-assembly of a ß-sandwich protein". Chemistry - A European Journal 15 46 (2009): 12672-12680. http://www.scopus.com/inward/record.url?eid=2-s2.0-71549124013&partnerID=MN8TOARS.
    10.1002/chem.200901410
  41. Oliveira, T.F.; Vonrhein, C.; Matias, P.M.; Venceslau, S.S.; Pereira, I.A.C.; Archer, M.. "The crystal structure of Desulfovibrio vulgaris dissimilatory sulfite reductase bound to DsrC provides novel insights into the mechanism of sulfate respiration". Journal of Biological Chemistry 283 49 (2008): 34141-34149. http://www.scopus.com/inward/record.url?eid=2-s2.0-57749097713&partnerID=MN8TOARS.
    10.1074/jbc.M805643200
  42. Gorynia, S.; Matias, P.M.; Bandeiras, T.M.; Donner, P.; Carrondo, M.A.. "Cloning, expression, purification, crystallization and preliminary X-ray analysis of the human RuvBL1-RuvBL2 complex". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 64 9 (2008): 840-846. http://www.scopus.com/inward/record.url?eid=2-s2.0-51149096210&partnerID=MN8TOARS.
    10.1107/S174430910802558X
  43. Oliveira, T.F.; Vonrhein, C.; Matias, P.M.; Venceslau, S.S.; Pereira, I.A.C.; Archer, M.; Marques, M.; et al. "Purification, crystallization and preliminary crystallographic analysis of a dissimilatory DsrAB sulfite reductase in complex with DsrC". Journal of Structural Biology 164 2 (2008): 236-239. http://www.scopus.com/inward/record.url?eid=2-s2.0-54049085708&partnerID=MN8TOARS.
    10.1016/j.jsb.2008.07.007
  44. Bandeiras, T.M.; Hillig, R.C.; Matias, P.M.; Eberspaecher, U.; Fanghänel, J.; Thomaz, M.; Miranda, S.; et al. "Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin". Acta Crystallographica Section D: Biological Crystallography 64 4 (2008): 339-353. http://www.scopus.com/inward/record.url?eid=2-s2.0-41949142073&partnerID=MN8TOARS.
    10.1107/S0907444907068217
  45. Crowley, P.B.; Matias, P.M.; Mi, H.; Firbank, S.J.; Banfield, M.J.; Dennison, C.. "Regulation of protein function: Crystal packing interfaces and conformational dimerization". Biochemistry 47 25 (2008): 6583-6589. http://www.scopus.com/inward/record.url?eid=2-s2.0-45749083319&partnerID=MN8TOARS.
    10.1021/bi800125h
  46. Carrondo, M.A.; Bento, I.; Matias, P.M.; Lindley, P.F.. "Crystallographic evidence for dioxygen interactions with iron proteins". Journal of Biological Inorganic Chemistry 12 4 (2007): 429-442. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247626051&partnerID=MN8TOARS.
    10.1007/s00775-007-0213-2
  47. Tatur, J.; Hagen, W.R.; Matias, P.M.. "Crystal structure of the ferritin from the hyperthermophilic archaeal anaerobe Pyrococcus furiosus". Journal of Biological Inorganic Chemistry 12 5 (2007): 615-630. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249874901&partnerID=MN8TOARS.
    10.1007/s00775-007-0212-3
  48. Simplício, A.L.; Matias, P.; Gilmer, J.F.; Clancy, J.M.. "Chiral separation and identification of ß-aminoketones of pharmacological interest by high performance liquid chromatography and capillary electrophoresis". Journal of Chromatography A 1120 1-2 (2006): 89-93. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744967923&partnerID=MN8TOARS.
    10.1016/j.chroma.2005.12.089
  49. Matias, P.M.; Gorynia, S.; Donner, P.; Carrondo, M.A.. "Crystal structure of the human AAA+ protein RuvBL1". Journal of Biological Chemistry 281 50 (2006): 38918-38929. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846007717&partnerID=MN8TOARS.
    10.1074/jbc.M605625200
  50. Gorynia, S.; Matias, P.M.; Gonçalves, S.; Coelho, R.; Lopes, G.; Thomaz, M.; Huber, M.; et al. "Expression, purification, crystallization and preliminary X-ray analysis of the human RuvB-like protein RuvBL1". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 62 1 (2006): 61-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646869063&partnerID=MN8TOARS.
    10.1107/S1744309105041400
  51. Rodrigues, M.L.; Oliveira, T.; Matias, P.M.; Martins, I.C.; Valente, F.M.A.; Pereira, I.A.C.; Archer, M.. "Crystallization and preliminary structure determination of the membrane-bound complex cytochrome c nitrite reductase from Desulfovibrio vulgaris Hildenborough". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 62 6 (2006): 565-568. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745129677&partnerID=MN8TOARS.
    10.1107/S1744309106016629
  52. Matias, P.M.; Pereira, I.A.C.; Soares, C.M.; Carrondo, M.A.. "Sulphate respiration from hydrogen in Desulfovibrio bacteria: A structural biology overview". Progress in Biophysics and Molecular Biology 89 3 (2005): 292-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-20444385906&partnerID=MN8TOARS.
    10.1016/j.pbiomolbio.2004.11.003
  53. Matias, P.M.; Tatur, J.; Carrondo, M.A.; Hagen, W.R.. "Crystallization and preliminary X-ray characterization of a ferritin from the hyperthermophilic archaeon and anaerobe Pyrococcus furiosus". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 61 5 (2005): 503-506. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645487880&partnerID=MN8TOARS.
    10.1107/S1744309105011516
  54. Bento, I.; Matias, P.M.; Baptista, A.M.; Da Costa, P.N.; Van Dongen, W.M.A.M.; Saraiva, L.M.; Schneider, T.R.; Soares, C.M.; Carrondo, M.A.. "Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome c 3 from Desulfovibrio desulfuricans ATCC 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at pH 7.6". Proteins: Structure, Function and Genetics 54 1 (2004): 135-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-0348047621&partnerID=MN8TOARS.
    10.1002/prot.10431
  55. Barros, M.T.; Matias, P.M.; Maycock, C.D.; Ventura, M.R.. "Aziridines as a Protecting and Directing Group. Stereoselective Synthesis of (+)-Bromoxone". Organic Letters 5 23 (2003): 4321-4323. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345359348&partnerID=MN8TOARS.
    10.1021/ol035576i
  56. Macedo, S.; Romão, C.V.; Mitchell, E.; Matias, P.M.; Liu, M.Y.; Xavier, A.V.; LeGall, J.; et al. "The nature of the di-iron site in the bacterio-ferritin from Desulfovibrio desulfuricans". Nature Structural Biology 10 4 (2003): 285-290. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037389839&partnerID=MN8TOARS.
    10.1038/nsb909
  57. Bento, I.; Teixeira, V.H.; Baptista, A.M.; Soares, C.M.; Matias, P.M.; Carrondo, M.A.. "Redox-Bohr and other cooperativity effects in the nine-heme cytochrome c from Desulfovibrio desulfuricans ATCC 27774: Crystallographic and modeling studies". Journal of Biological Chemistry 278 38 (2003): 36455-36469. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141815636&partnerID=MN8TOARS.
    10.1074/jbc.M301745200
  58. Abreu, I.A.; Lourenço, A.I.; Xavier, A.V.; LeGall, J.; Coelho, A.V.; Matias, P.M.; Pinto, D.M.; et al. "A novel iron centre in the split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774". Journal of Biological Inorganic Chemistry 8 3 (2003): 360-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037326047&partnerID=MN8TOARS.
  59. Matias, P.M.; Coelho, A.V.; Valente, F.M.A.; Plácido, D.; LeGall, J.; Xavier, A.V.; Pereira, I.A.C.; Carrondo, M.A.. "Sulfate respiration in Desulfovibrio vulgaris Hildenborough: Structure of the 16-heme cytochrome c HmcA at 2.5-Å resolution and a view of its role in transmembrane electron transfer". Journal of Biological Chemistry 277 49 (2002): 47907-47916. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037033048&partnerID=MN8TOARS.
    10.1074/jbc.M207465200
  60. Enguita, F.J.; Matias, P.M.; Martins, L.O.; Plácido, D.; Henriques, A.O.; Carrondo, M.A.. "Spore-coat laccase CotA from Bacillus subtilis: Crystallization and preliminary X-ray characterization by the MAD method". Acta Crystallographica Section D: Biological Crystallography 58 9 (2002): 1490-1493. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036713444&partnerID=MN8TOARS.
    10.1107/S0907444902011575
  61. Bonifácio, M.J.; Archer, M.; Rodrigues, M.L.; Matias, P.M.; Learmonth, D.A.; Carrondo, M.A.; Soares-da-Silva, P.. "Kinetics and crystal structure of catechol-O-methyltransferase complex with co-substrate and a novel inhibitor with potential therapeutic application". Molecular Pharmacology 62 4 (2002): 795-805. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036784071&partnerID=MN8TOARS.
    10.1124/mol.62.4.795
  62. Matias, P.M.; Carrondo, M.A.; Coelho, R.; Thomaz, M.; Zhao, X.-Y.; Wegg, A.; Crusius, K.; Egner, U.; Donner, P.. "Structural basis for the glucocorticoid response in a mutant human androgen receptor (ARccr) derived from an androgen-independent prostate cancer". Journal of Medicinal Chemistry 45 7 (2002): 1439-1446. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037187408&partnerID=MN8TOARS.
    10.1021/jm011072j
  63. Louro, R.O.; Bento, I.; Matias, P.M.; Catarino, T.; Baptista, A.M.; Soares, C.M.; Carrondo, M.A.; Turner, D.L.; Xavier, A.V.. "Conformational Component in the Coupled Transfer of Multiple Electrons and Protons in a Monomeric Tetraheme Cytochrome". Journal of Biological Chemistry 276 47 (2001): 44044-44051. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035941269&partnerID=MN8TOARS.
    10.1074/jbc.M107136200
  64. Learmonth, D.A.; Benes, J.; Parada, A.; Hainzl, D.; Beliaev, A.; Bonifácio, M.J.; Matias, P.M.; et al. "Synthesis, anticonvulsant properties and pharmacokinetic profile of novel 10,11-dihydro-10-oxo-5H-dibenz/b,f/azepine-5-carboxamide derivatives". European Journal of Medicinal Chemistry 36 3 (2001): 227-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035310336&partnerID=MN8TOARS.
    10.1016/S0223-5234(01)01220-X
  65. Matias, P.M.; Soares, C.M.; Saraiva, L.M.; Coelho, R.; Morais, J.; Le Gall, J.; Carrondo, M.A.. "[NiFe] hydrogenase from Desulfovibrio desulfuricans ATCC 27774: Gene sequencing, three-dimensional structure determination and refinement at 1.8 Å and modelling studies of its interaction with the tetrahaem cytochrome c3". Journal of Biological Inorganic Chemistry 6 1 (2001): 63-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034846760&partnerID=MN8TOARS.
    10.1007/s007750000167
  66. Coelho, A.V.; Macedo, S.; Matias, P.M.; Thompson, A.W.; LeGall, J.; Carrondo, M.A.. "Structure determination of bacterioferritin from Desulfovibrio desulfuricans by the MAD method at the Fe K-edge". Acta Crystallographica Section D: Biological Crystallography 57 2 (2001): 326-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035128171&partnerID=MN8TOARS.
    10.1107/S0907444900015286
  67. Frazão, C.; Silva, G.; Gomes, C.M.; Matias, P.; Coelho, R.; Sieker, L.; Macedo, S.; et al. "Structure of a dioxygen reduction enzyme from Desulfovibrio gigas". Nature Structural Biology 7 11 (2000): 1041-1045. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033767236&partnerID=MN8TOARS.
    10.1038/80961
  68. Costa Pessoa, J.; Cavaco, I.; Correia, I.; Tomaz, I.; Duarte, T.; Matias, P.M.. "Oxovanadium(IV) complexes with aromatic aldehydes". Journal of Inorganic Biochemistry 80 1-2 (2000): 35-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034732818&partnerID=MN8TOARS.
    10.1016/S0162-0134(00)00037-4
  69. Matias, P.M.; Donner, P.; Coelho, R.; Thomaz, M.; Peixoto, C.; Macedo, S.; Otto, N.; et al. "Structural evidence for ligand specificity in the binding domain of the human androgen receptor: Implications for pathogenic gene mutations". Journal of Biological Chemistry 275 34 (2000): 26164-26171. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034714276&partnerID=MN8TOARS.
    10.1074/jbc.M004571200
  70. Matias, P.M.; Coelho, R.; Pereira, I.A.C.; Coelho, A.V.; Thompson, A.W.; Sieker, L.C.; Le Gall, J.; Carrondo, M.A.. "The primary and three-dimensional structures of a nine-haem cytochrome c from Desulfovibrio desulfuricans ATCC 27774 reveal a new member of the Hmc family". Structure 7 2 (1999): 119-130. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033081499&partnerID=MN8TOARS.
    10.1016/S0969-2126(99)80019-7
  71. Matias, P.M.; Saraiva, L.M.; Soares, C.M.; Coelho, A.V.; LeGall, J.; Carrondo, M.A.. "Nine-haem cytochrome c from Desulfovibrio desulfuricans ATCC 27774: Primary sequence determination, crystallographic refinement at 1.8 and modelling studies of its interaction with the tetrahaem cytochrome c3". Journal of Biological Inorganic Chemistry 4 4 (1999): 478-494. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032836538&partnerID=MN8TOARS.
    10.1007/s007750050334
  72. Simões, P.; Matias, P.M.; Morais, J.; Wilson, K.; Dauter, Z.; Carrondo, M.A.. "Refinement of the three-dimensional structures of cytochrome C3 from Desulfovibrio vulgaris hildenborough at 1.67 Å resolution and from Desulfovibrio desulfuricans ATCC 27774 at 1.6 Å resolution". Inorganica Chimica Acta 273 1-2 (1998): 213-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-0040598957&partnerID=MN8TOARS.
  73. Costa Pessoa, J.; Duarte, M.T.; Gillard, R.D.; Madeira, C.; Matias, P.M.; Tomaz, I.. "Preparation of [VO(sal-L-Trp)(H2O)] (sal-L-Trp = N-salicylidene-L-tryptophanate) and characterisation of an unusual product obtained from its solutions in water-pyridine". Journal of the Chemical Society - Dalton Transactions 23 (1998): 4015-4020. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748660729&partnerID=MN8TOARS.
  74. Matias, P.M.; Morais, J.; Coelho, A.V.; Meijers, R.; Gonzalez, A.; Thompson, A.W.; Sieker, L.; LeGall, J.; Carrondo, M.A.. "A preliminary analysis of the three-dimensional structure of dimeric di- haem split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774 at 2.5-Å resolution using the MAD phasing method: A novel cytochrome fold with a stacked-haem arrangement". Journal of Biological Inorganic Chemistry 2 4 (1997): 507-514. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030773395&partnerID=MN8TOARS.
    10.1007/s007750050162
  75. Coelho, A.V.; Matias, P.; Fülöp, V.; Thompson, A.; Gonzalez, A.; Carrondo, M.A.. "Desulfoferrodoxin structure determined by MAD phasing and refinement to 1.9-Å resolution reveals a unique combination of a tetrahedral FeS4 centre with a square pyramidal FeSN4 centre". Journal of Biological Inorganic Chemistry 2 6 (1997): 680-689. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031459603&partnerID=MN8TOARS.
    10.1007/s007750050184
  76. Cavaco, I.; Pessoa, J.C.; Duarte, M.T.; Gillard, R.D.; Matias, P.. "Molecular structure of [VO(sal-D,L-Asn)(py)(H2O)] and reaction to produce coumarin-3-carboxamide". Chemical Communications 11 (1996): 1365-1366. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001534843&partnerID=MN8TOARS.
  77. Coelho, A.V.; Matias, P.M.; Sieker, L.C.; Morais, J.; Carrondo, M.A.; Lampreia, J.; Costa, C.; et al. "Preliminary crystallographic analysis and further characterization of a dodecaheme cytochrome c from Desulfovibrio desulfuricans ATCC 27774". Acta Crystallographica Section D: Biological Crystallography 52 6 (1996): 1202-1208. http://www.scopus.com/inward/record.url?eid=2-s2.0-12644312235&partnerID=MN8TOARS.
    10.1107/S090744499600738X
  78. Coelho, A.V.; Matias, P.M.; Carrondo, M.A.; Tavares, P.; Moura, J.J.G.; Moura, I.; Fulop, V.; Hajdu, J.; Le Gall, J.. "Preliminary crystallographic analysis of the oxidized form of a two mono- nuclear iron centres protein from Desulfovibrio desulfuricans ATCC 27774". Protein Science 5 6 (1996): 1189-1191. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030015101&partnerID=MN8TOARS.
  79. Matias, P.M.; Morais, J.; Coelho, R.; Carrondo, M.A.; Wilson, K.; Dauter, Z.; Sieker, L.. "Cytochrome c3 from Desulfovibrio gigas: Crystal structure at 1.8 Å resolution and evidence for a specific calcium-binding site". Protein Science 5 7 (1996): 1342-1354. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029659034&partnerID=MN8TOARS.
  80. Cavaco, I.; Costa Pessoa, J.; Duarte, M.T.; Henriques, R.T.; Matias, P.M.; Gillard, R.D.. "Crystal and molecular structure of [V2O3(sal-L-val)2(H2O)] (sal-L-val = N-salicylidene-L-valinate) and spectroscopic properties of related complexes". Journal of the Chemical Society - Dalton Transactions 9 (1996): 1989-1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748497817&partnerID=MN8TOARS.
  81. Cavaco, I.; Pessoa, J.C.; Luz, S.M.; Duarte, M.T.; Matias, P.M.; Henriques, R.T.; Gillard, R.D.. "N-salicylideneamino-acidate complexes of oxovanadium(IV)-II. Synthesis, characterization and deamination of an n-salicylideneglycylglycinato complex". Polyhedron 14 3 (1995): 429-439. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748501120&partnerID=MN8TOARS.
    10.1016/0277-5387(94)00247-C
  82. Frazao, C.; Dias, J.M.; Matias, P.M.; Romao, M.J.; Carrondo, M.A.; Hervas, M.; Navarro, J.A.; De La Rosa, M.; Sheldrick, G.M.. "Cytochrome c6 from the green alga Monoraphidium braunii. Crystallization and preliminary diffraction studies". Acta Crystallographica - Section D Biological Crystallography 51 2 (1995): 232-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029132455&partnerID=MN8TOARS.
    10.1107/S0907444994005184
  83. Cavaco, I.; Pessoa, J.C.; Costa, D.; Duarte, M.T.; Gillard, R.D.; Matias, P.. "N-salicylideneamino acidate complexes of oxovanadium(IV). Part 1. Crystal and molecular structures and spectroscopic properties". Journal of the Chemical Society, Dalton Transactions 2 (1994): 149-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049081957&partnerID=MN8TOARS.
    10.1039/DT9940000149
  84. Carrondo, M.A.A.F.d.C.T.; Matias, P.M.; Heggie, W.; Page, P.R.. "Molecular structure of 6-methyleneoxytetracycline hydrobromide". Structural Chemistry 5 2 (1994): 73-77. http://www.scopus.com/inward/record.url?eid=2-s2.0-0013108268&partnerID=MN8TOARS.
    10.1007/BF02265348
  85. Morgado, J.; Santos, I.C.; Henriques, R.T.; Fourmigué, M.; Matias, P.; Veiros, L.F.; Calhorda, M.J.; et al. "Molecular metals based on 1,2,7,8-tetrahydrodicyclopenta[cd:lm]perylene and iodine, (CPP)2(I3)1-d". Chemistry of Materials 6 12 (1994): 2309-2316. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242509560&partnerID=MN8TOARS.
  86. Frazao, C.; Morais, J.; Matias, P.M.; Carrondo, M.A.. "Crystallization and preliminary X-ray diffraction analysis of tetra-heme cytochrome c3 from sulfate- and nitrate-reducing Desulfovibrio desulfuricans ATCC 27774". Acta Crystallographica Section D: Biological Crystallography 50 2 (1994): 233-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028054476&partnerID=MN8TOARS.
    10.1107/S0907444993011631
  87. C.T. Carrondo, M.A.A.F.d.; Dias, A.R.; Garcia, M.H.; Matias, P.; Piendade, M.F.M.; Villa de Brito, M.J.. "Indium(III) thiolate-bridged molybdenocene complexes: crystal structure of [InCl2MoCp2(¿-SEt) 22][BPh4] · (CH3)2CO". Journal of Organometallic Chemistry 466 1-2 (1994): 159-165. http://www.scopus.com/inward/record.url?eid=2-s2.0-0041377401&partnerID=MN8TOARS.
  88. Matias, P.M.; Frazao, C.; Morais, J.; Coll, M.; Carrondo, M.A.. "Structure analysis of cytochrome c 3 from Desulfovibrio vulgaris Hildenborough at 1.9 Å resolution". Journal of Molecular Biology 234 3 (1993): 680-699. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027142037&partnerID=MN8TOARS.
  89. Cavaco, I.; Pessoa, J.C.; Duarte, M.T.; Matias, P.M.; Henriques, R.T.. "Synthesis and structural characterization of a polyoxovanadate coordination complex [V4O8(CH3O)4(bipy)2] with a tetrametallate core". Polyhedron 12 10 (1993): 1231-1237. http://www.scopus.com/inward/record.url?eid=2-s2.0-0006912643&partnerID=MN8TOARS.
  90. Calhorda, M.J.; de C.T. Carrondo, M.A.A.F.; Dias, A.R.; FéIix, V.; Galvão, A.M.; Garcia, M.H.; Matias, P.M.; Villa de Brito, M.J.. "Synthesis, characterization and bonding of fulvalene dimolybdenum(III) and ditungsten(III) cations with one thiolate bridging ligand. Crystal structure of [Mo2(µ-¿5:...". Journal of Organometallic Chemistry 453 2 (1993): 231-240. http://www.scopus.com/inward/record.url?eid=2-s2.0-0009498237&partnerID=MN8TOARS.
  91. Terry, C.J.; Damas, A.M.; Oliveira, P.; Sariava, M.J.M.; Alves, I.L.; Costa, P.P.; Matias, P.M.; Sakaki, Y.; Blake, C.C.F.. "Structure of Met30 variant of transthyretin and its amyloidogenic implications". EMBO Journal 12 2 (1993): 735-741. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027518443&partnerID=MN8TOARS.
  92. Calhorda, M.J.; Dias, A.R.; Duarte, M.T.; Martins, A.M.; Matias, P.M.; Romão, C.C.. "Methylisocyanide derivatives of molybdenocene and tungstenocene: preparation, reactivity and electronic structure: crystal structures of [(¿5-C5H5)2WBr(CNMe)]Br and [(¿5-C5H5)2MoC{N(H)CH3}N(H)C{N(H)CH3}][BF4]2· CH3CN". Journal of Organometallic Chemistry 440 1-2 (1992): 119-144. http://www.scopus.com/inward/record.url?eid=2-s2.0-0013671629&partnerID=MN8TOARS.
  93. de C.T. Carrondo, M.A.A.F.; Dias, A.R.; Garcia, M.H.; Matias, P.M.; Robalo, M.P.; Green, M.L.H.; Higgins, J.; Yang, Y.Y.. "Syntheses and reactivity of p-substituted benzonitrile complexes derived from dicyclopentadienyl-molybdenum and -tungsten. Oxidative electrochemistry. The crystal structure of [Mo(¿5-C5H5)2(SC6H5)(p-(CH3)2NC6H4CN)][PF6]". Journal of Organometallic Chemistry 395 3 (1990): 279-292. http://www.scopus.com/inward/record.url?eid=2-s2.0-0040642631&partnerID=MN8TOARS.
  94. Nieto de Castro, C.A.; Fareleira, J.M.N.A.; Matias, P.M.; Ramires, M.L.V.; Canelas Pais, A.A.C.; Varandas, A.J.C.. "Thermophysical properties of alkali metal vapours. Part I. Theoretical calculation of the properties of monatomic systems". Berichte der Bunsengesellschaft/Physical Chemistry Chemical Physics 94 1 (1990): 53-59. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025262978&partnerID=MN8TOARS.
  95. Matias, P.M.; Jeffrey, G.A.; Wingert, L.M.; Ruble, J.R.. "Single crystal neutron diffraction analysis (15 K) and ab initio molecular orbital calculations for ethylene carbonate". Journal of Molecular Structure: THEOCHEM 184 3-4 (1989): 247-260. http://www.scopus.com/inward/record.url?eid=2-s2.0-1342296814&partnerID=MN8TOARS.
  96. Matias, P. M.; Jeffrey, G. A.; Ruble, J. R.. "Structures of the E,Z (cis–trans) isomer of diacetamide and the 1:1 complex with acetamide at 123 K. Ab-initio molecular orbital calculations on the Z,Z (trans–trans), E,Z (cis–trans) and E,E (cis–cis) isomers of diacetamide". Acta Crystallographica Section B Structural Science 44 5 (1988): 516-522. http://dx.doi.org/10.1107/s0108768188003520.
    10.1107/s0108768188003520
  97. De Vos, A.M.; Tong, L.; Milburn, M.V.; Matias, P.M.; Jancarik, J.; Noguchi, S.; Nishimura, S.; et al. "Three-dimensional structure of an oncogene protein: Catalytic domain of human c-H-ras p21". Science 239 4842 (1988): 888-893. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023857409&partnerID=MN8TOARS.
  98. Kim, S.-H.; De Vos, A.M.; Tong, L.; Milburn, M.V.; Matias, P.M.; Jancarik, J.; Ohtsuka, E.; Nishimura, S.. "ras Oncogene proteins: Three-dimensional structures, functional implications, and a model for signal transducer". Cold Spring Harbor Symposia on Quantitative Biology 53 1 (1988): 273-281. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024145902&partnerID=MN8TOARS.
  99. Duda, A.; Buschmann, J.; Bulow, R.; Luger, P.; McMullan, R. K.; Jeffrey, G. A.; Ruble, J.; Matias, P.. "NEW STRUCTURAL STUDIES ON BULLVALENE MOLECULES". Zeitschrift Fur Kristallographie 174 1-4 (1986): 42-44.
  100. Matias, P.M.; Jeffrey, G.A.. "The crystal structure of isopropyl 1-thio-ß-d-galactopyranoside monoydrate at 123 K". Carbohydrate Research 153 2 (1986): 217-226. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022803262&partnerID=MN8TOARS.
  101. Luger, P.; Buschmann, J.; McMullan, R.K.; Ruble, J.R.; Matias, P.; Jeffrey, G.A.. "Single crystal neutron diffraction refinement of bullvalene at 110 K". Journal of the American Chemical Society 108 24 (1986): 7825-7827. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845375391&partnerID=MN8TOARS.
  102. CARRONDO, MAAFDT; MATIAS, PM; JEFFREY, GA. "BIS(TERT-BUTYLTHIO)BIS(ETA-5-CYCLOPENTADIENYL)MOLYBDENUM(IV), [MO(C5H5)2(C4H9S)2]". ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS 40 JUN (1984): 932-934.
    10.1107/S0108270184006314
Preprint
  1. I.B. Trindade; F. Rollo; S. Todorovic; T. Catarino; E. Moe; P.M. Matias; M. Piccioli; R.O. Louro. "The structure of a novel ferredoxin – FhuF, a ferric-siderophore reductase from E. coli K-12 with a novel 2Fe-2S cluster coordination". 2023. https://doi.org/10.1101/2023.07.04.547673.
    10.1101/2023.07.04.547673
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/03/20 A structural overview of RuvBL1, RuvBL2 and their complexes IMpaCT Tomography Workshop
Weizmann Institute of Science (Rehovot, Israel)
2021/12/14 Catching up with the CryoEM Resolution Revolution
ITQB NOVA (virtual) (Oeiras, Portugal)
2019/06/14 Improving the O2 tolerance of a [NiFeSe] hydrogenase 1st National Crystallographic Meeting
Universidade de Aveiro (Aveiro, Portugal)
2019/04/01 Improving the O2 tolerance of a [NiFeSe] hydrogenase 12th International Conference on Hydrogenases and other Redox (Bio)catalysts for Energy Conversion
(Lisboa, Portugal)
2018/07/03 The Portuguese Beam Allocation Group at the ESRF: a 19-year old success history (1999-2018) Encontro Ciência 2018
(Lisboa, Portugal)
2014/11/04 A structural Overview of Pontin (RuvBL1), Reptin (RuvBL2) and their complex(es) PSDI 2014 – 22nd Protein Structure Determination in Industry Conference
Merck KgaA (Cascais)
2013/07/09 Redox State-Dependent Structural Changes in [NiFeSe] Hydrogenase from Desulfovibrio vulgaris Hildenborough 10th International Hydrogenase Conference
(Szeged, Hungary)
2013/02/14 The Portuguese MX Block Allocation Group at the ESRF: a 14-year success history (1999-2013) 2º Encontro Nacional de Utilizadores de Radiação Sincrotrão
(Lisboa)
2012/10/17 A structural Overview of Pontin (RuvBL1), Reptin (RuvBL2) and their complex(es) First International Meeting on Reptin and Pontin
(Bordéus, France)
2011/05/06 The Three Dimensional Structure of a Dodecameric Molecular Machine – The RuvBL1/RuvBL2 Complex INTERBIO Symposium Frontiers in Protein Research
(Oeiras, Portugal)
2010/09/14 Structural Analysis of Thermus thermophilus HB27 Mannosyl-3-Phosphoglycerate Synthase 8th International Congress on Extremophiles
(Ponta Delgada, Portugal)
2006/07/24 Three-dimensional structure of a ferritin from the hyperthermophilic archaeon and anaerobe Pyrococcus furiosus 2006 Annual Meeting of the American Crystallographic Association
American Crystallographic Association (Honolulu)
2005/08/25 The activation process of D.desulfuricans ATCC 27774 [NiFe] Hydrogenase IUCr 2005 - XX Congress of the International Union of Crystallography
International Union of Crystallography (Florença, Italy)
2003/08/26 Sulfate respiration in Desulfovibrio bacteria: a Short Crystallographic Overview ECM-21 - 21st congress of the European Crystallographic Association
European Crystallographic Association (Durban, South Africa)
2001/07/01 Hydrogen recycling in D.desulfuricans ATCC 27774: crystallographic and molecular modelling studies on the periplasmic electron transfer chain Joint 27th FEBS Meeting and PABMB Meeting
FEBS (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/01/02 - 2023/12/31 Structure and Function of a Dodecameric Molecular Machine: the Human RuvBL1/RuvBL2 Complex and its Role in Disease
Co-supervisor
 Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/10/01 - 2023/09/30 Biocatalytic H2 production with a high activity [NiFeSe] hydrogenase
Co-supervisor
 Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/09/01 - 2022/03/16 X-ray crystal structure of Human GAPDH with a selective inhibitor
Co-supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015/09/01 - 2020/12/31 Structural and Functional insights into a dodecameric machine
Co-supervisor
 Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015/09/01 - 2019/11/07 Engineering a [NiFeSe] Hydrogenase for an efficient hydrogen production
Co-supervisor
 Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/09/01 - 2019/02/15 Cyclophilin D as a multiple sclerosis and cardiovascular disease drug target
Co-supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/09/01 - 2018/10/31 CRYSTAL STRUCTURE OF BONE MARROW TYROSINE KINASE FROM CHROMOSOME X WITH COVALENT LIGANDS
Co-supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2013/01/01 - 2017/11/27 Structural insights into the human multifunctional protein RuvBL2
Co-supervisor
 Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010/09/01 - 2014/12/17 Structural and functional studies of a high-activity [NiFeSe] hydrogenase
Co-supervisor
 Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2005/09/01 - 2012/05/11 Structural studies on the structure-function relationship in a glycosyltransferase, a phosphatase and an oxidorreductase.
Supervisor
 Bioquímica (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/07/10 - 2022/07/15 7th European Crystallographic School - ECS7 (2022/07/10 - 2022/07/15)
Workshop (Member of the Organising Committee)
 Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/03/31 - 2019/04/04 12th International Conference on Hydrogenases and other Redox (Bio)catalysts for Energy Conversion (2019/03/31 - 2019/04/04)
Congress (Member of the Organising Committee)
 Universidade Nova de Lisboa, Portugal
2016/06/17 - 2016/06/17 5º Encontro Nacional de Utilizadores de Radiação Sincrotrão (2016/06/17)
Meeting (Member of the Organising Committee)
 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/01/31 - 2016/02/02 BioStruct-X Workshop on Ensemble Refinement of Protein Crystal Structures (2016/01/31)
Workshop (Member of the Organising Committee)
 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014/10/10 - 2014/10/12 Second International Workshop on Reptin and Pontin, 10 a 12 de Outubro de 2014, Oeiras, Portugal. (2014/10/10)
Workshop (Member of the Organising Committee)
 Instituto de Biologia Experimental e Tecnológica, Portugal
2006/07/02 - 2006/07/07 Eurobic 8, the 8th European Biological Chemistry Conference, 2 a 7 de Julho de 2006, Aveiro, Portugal (2006/07/02)
Congress (Member of the Organising Committee)
 Universidade de Aveiro, Portugal