| Journal article |
- Dinami, R.; Pompili, L.; Petti, E.; Porru, M.; D'Angelo, C.; Di Vito, S.; Rizzo, A.; et al. "MiR-182-3p targets TRF2 and impairs
tumor growth of triple-negative breast cancer". EMBO Molecular Medicine 15 1 (2023):
10.15252/emmm.202216033
- Ines Rodrigues Lopes; Laura Maria Alcantara; Ricardo Jorge Silva; Jerome Josse; Elena Pedrero Vega; Ana Marina Cabrerizo;
Melanie Bonhomme; et al. "Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals
intracellular lifestyle as a prevalent feature". Nature Communications 13 1 (2022):
10.1038/s41467-022-34790-9
- Carmen Aguilar; Susana Costa; Claire Maudet; R. P. Vivek-Ananth; Sara Zaldívar-López; Juan J. Garrido; Areejit Samal; Miguel
Mano; Ana Eulalio. "Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected
and bystander cells". Nature Communications (2021):
10.1038/s41467-021-23593-z
- Clivia Lisowski; Jane Dias; Susana Costa; Ricardo Jorge Silva; Miguel Mano; Ana Eulalio. "Dysregulated endolysosomal trafficking
in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication". Autophagy (2021):
10.1080/15548627.2021.1999561
- João Paulo Silva Nunes; Pauline Andrieux; Pauline Brochet; Rafael Ribeiro Almeida; Eduardo Kitano; André Kenji Honda; Leo
Kei Iwai; et al. "Co-Exposure of Cardiomyocytes to IFN-¿ and TNF-a Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress".
Frontiers in Immunology 12 (2021):
10.3389/fimmu.2021.755862
- Aguilar, C.; Cruz, A.R.; Rodrigues Lopes, I.; Maudet, C.; Sunkavalli, U.; Silva, R.J.; Sharan, M.; et al. "Functional screenings
reveal different requirements for host microRNAs in Salmonella and Shigella infection". Nature Microbiology 5 1 (2020):
192-205. # co-last author.
10.1038/s41564-019-0614-3
- Sorino, C.; Catena, V.; Bruno, T.; De Nicola, F.; Scalera, S.; Bossi, G.; Fabretti, F.; et al. "Che-1/AATF binds to RNA polymerase
I machinery and sustains ribosomal RNA gene transcription". Nucleic Acids Research 48 11 (2020): 5891-5906.
10.1093/NAR/GKAA344
- Bertolio, R.; Napoletano, F.; Mano, M.; Maurer-Stroh, S.; Fantuz, M.; Zannini, A.; Bicciato, S.; Sorrentino, G.; Del Sal,
G.. "Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism". Nature Communications
10 1 (2019):
10.1038/s41467-019-09152-7
- Aguilar, C.; Mano, M.; Eulalio, A.. "Multifaceted roles of microRNAs in host-bacterial pathogen interaction". Microbiology
Spectrum 7 3 (2019):
10.1128/microbiolspec.BAI-0002-2019
- De Souza Lima, I.M.; Schiavinato, J.L.D.S.; Paulino Leite, S.B.; Sastre, D.; Bezerra, H.L.D.O.; Sangiorgi, B.; Corveloni,
A.C.; et al. "High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency
and differentiation". Stem Cell Research and Therapy 10 1 (2019):
10.1186/s13287-019-1318-6
- Ali, H.; Mano, M.; Braga, L.; Naseem, A.; Marini, B.; Vu, D.M.; Collesi, C.; et al. "Cellular TRIM33 restrains HIV-1 infection
by targeting viral integrase for proteasomal degradation". Nature Communications 10 1 (2019):
10.1038/s41467-019-08810-0
- Torrini, C.; Cubero, R.J.; Dirkx, E.; Braga, L.; Ali, H.; Prosdocimo, G.; Gutierrez, M.I.; et al. "Common Regulatory Pathways
Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation". Cell Reports 27 9 (2019): 2759-2771.e5.
10.1016/j.celrep.2019.05.005
- Rodrigues Lopes, I.; Silva, R.J.; Caramelo, I.; Eulalio, A.; Mano, M.. "Shedding light on microRNA function via microscopy-based
screening". Methods 152 (2019): 55-64.
10.1016/j.ymeth.2018.09.011
- Aguilar, C.; Mano, M.; Eulalio, A.. "MicroRNAs at the Host–Bacteria Interface: Host Defense or Bacterial Offense". Trends
in Microbiology 27 3 (2019): 206-218.
10.1016/j.tim.2018.10.011
- Bellazzo, A.; Di Minin, G.; Valentino, E.; Sicari, D.; Torre, D.; Marchionni, L.; Serpi, F.; et al. "Cell-autonomous and cell
non-autonomous downregulation of tumor suppressor DAB2IP by microRNA-149-3p promotes aggressiveness of cancer cells". Cell
Death and Differentiation 25 7 (2018): 1224-1238.
10.1038/s41418-018-0088-5
- Andriani, F.; Majorini, M.T.; Mano, M.; Landoni, E.; Miceli, R.; Facchinetti, F.; Mensah, M.; et al. "MiR-16 regulates the
pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner".
Journal of Hematology and Oncology 11 1 (2018):
10.1186/s13045-018-0594-4
- Majorini, M.T.; Manenti, G.; Mano, M.; De Cecco, L.; Conti, A.; Pinciroli, P.; Fontanella, E.; et al. "CIAP1 regulates the
EGFR/Snai2 axis in triple-negative breast cancer cells". Cell Death and Differentiation 25 12 (2018): 2147-2164.
10.1038/s41418-018-0100-0
- Tawk, C.; Nigro, G.; Rodrigues Lopes, I.; Aguilar, C.; Lisowski, C.; Mano, M.; Sansonetti, P.; Vogel, J.; Eulalio, A.. "Stress-induced
host membrane remodeling protects from infection by non-motile bacterial pathogens". EMBO Journal 37 23 (2018):
10.15252/embj.201798529
- Ingallina, E.; Sorrentino, G.; Bertolio, R.; Lisek, K.; Zannini, A.; Azzolin, L.; Severino, L.U.; et al. "Mechanical cues
control mutant p53 stability through a mevalonate-RhoA axis". Nature Cell Biology 20 1 (2018): 28-35.
10.1038/s41556-017-0009-8
- Cunningham, T.J.; Yu, M.S.; McKeithan, W.L.; Spiering, S.; Carrette, F.; Huang, C.-T.; Bushway, P.J.; et al. "Id genes are
essential for early heart formation". Genes and Development 31 13 (2017): 1325-1338.
10.1101/gad.300400.117
- Sunkavalli, U.; Aguilar, C.; Silva, R.J.; Sharan, M.; Cruz, A.R.; Tawk, C.; Maudet, C.; Mano, M.; Eulalio, A.. "Analysis of
host microRNA function uncovers a role for miR-29b-2-5p in Shigella capture by filopodia". PLoS Pathogens 13 4 (2017):
10.1371/journal.ppat.1006327
- Sorrentino, G.; Ruggeri, N.; Zannini, A.; Ingallina, E.; Bertolio, R.; Marotta, C.; Neri, C.; et al. "Glucocorticoid receptor
signalling activates YAP in breast cancer". Nature Communications 8 (2017):
10.1038/ncomms14073
- Dinami, R.; Buemi, V.; Sestito, R.; Zappone, A.; Ciani, Y.; Mano, M.; Petti, E.; et al. "Epigenetic silencing of miR-296 and
miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells". Oncotarget
8 56 (2017): 95674-95691.
10.18632/oncotarget.21180
- Cunha, P.P.; Costa, P.M.; Morais, C.M.; Lopes, I.R.; Cardoso, A.M.; Cardoso, A.L.; Mano, M.; Jurado, A.S.; Pedroso De Lima,
M.C.P.. "High-throughput screening uncovers miRNAs enhancing glioblastoma cell susceptibility to tyrosine kinase inhibitors".
Human Molecular Genetics 26 22 (2017): 4375-4387.
10.1093/hmg/ddx323
- Conti, A.; Majorini, M.T.; Fontanella, E.; Bardelli, A.; Giacca, M.; Delia, D.; Mano, M.; Lecis, D.. "Lemur tyrosine kinase
2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members". Cancer
Letters 389 (2017): 59-69.
10.1016/j.canlet.2016.12.025
- Eulalio, A.; Mano, M.. "MicroRNA Screening and the Quest for Biologically Relevant Targets". Journal of Biomolecular Screening
20 8 (2015): 1003-1017.
10.1177/1087057115578837
- Mano, M.; Ippodrino, R.; Zentilin, L.; Zacchigna, S.; Giacca, M.. "Genome-wide RNAi screening identifies host restriction
factors critical for in vivo AAV transduction". Proceedings of the National Academy of Sciences of the United States of
America 112 36 (2015): 11276-11281. # corresponding
author.
10.1073/pnas.1503607112
- Costa, P.M.; Cardoso, A.L.; Mano, M.; de Lima, M.C.P.. "MicroRNAs in glioblastoma: Role in pathogenesis and opportunities
for targeted therapies". CNS and Neurological Disorders - Drug Targets 14 2 (2015): 222-238.
10.2174/1871527314666150116123610
- Peche, L.Y.; Ladelfa, M.F.; Toledo, M.F.; Mano, M.; Laiseca, J.E.; Schneider, C.; Monte, M.. "Human MageB2 protein expression
enhances E2F transcriptional activity, cell proliferation, and resistance to ribotoxic stress". Journal of Biological Chemistry
290 49 (2015): 29652-29662.
10.1074/jbc.M115.671982
- Maudet, C.; Mano, M.; Eulalio, A.. "MicroRNAs in the interaction between host and bacterial pathogens". FEBS Letters
588 22 (2014): 4140-4147.
10.1016/j.febslet.2014.08.002
- Sorrentino, G.; Ruggeri, N.; Specchia, V.; Cordenonsi, M.; Mano, M.; Dupont, S.; Manfrin, A.; et al. "Metabolic control of
YAP and TAZ by the mevalonate pathway". Nature Cell Biology 16 4 (2014): 357-366.
10.1038/ncb2936
- Arnoldi, F.; De Lorenzo, G.; Mano, M.; Schraner, E.M.; Wild, P.; Eichwald, C.; Burrone, O.R.. "Rotavirus increases levels
of lipidated LC3 supporting accumulation of infectious progeny virus without inducing autophagosome formation". PLoS ONE
9 4 (2014):
10.1371/journal.pone.0095197
- Zecchin, A.; Pattarini, L.; Gutierrez, M.I.; Mano, M.; Mai, A.; Valente, S.; Myers, M.P.; Pantano, S.; Giacca, M.. "Reversible
acetylation regulates vascular endothelial growth factor receptor-2 activity". Journal of Molecular Cell Biology 6
2 (2014): 116-127.
10.1093/jmcb/mju010
- Verardo, R.; Piazza, S.; Klaric, E.; Ciani, Y.; Bussadori, G.; Marzinotto, S.; Mariuzzi, L.; et al. "Specific mesothelial
signature marks the heterogeneity of mesenchymal stem cells from high-grade serous ovarian cancer". Stem Cells 32 11
(2014): 2998-3011.
10.1002/stem.1791
- Maudet, C.; Mano, M.; Sunkavalli, U.; Sharan, M.; Giacca, M.; Förstner, K.U.; Eulalio, A.. "Functional high-throughput screening
identifies the miR-15 microRNA family as cellular restriction factors for Salmonella infection". Nature Communications
5 (2014):
10.1038/ncomms5718
- Ottaviani, G.; Gobbo, M.; Sturnega, M.; Martinelli, V.; Mano, M.; Zanconati, F.; Bussani, R.; et al. "Effect of class IV laser
therapy on chemotherapy-induced oral mucositis: A clinical and experimental study". American Journal of Pathology 183
6 (2013): 1747-1757.
10.1016/j.ajpath.2013.09.003
- Carrer, A.; Moimas, S.; Zacchigna, S.; Pattarini, L.; Zentilin, L.; Ruozi, G.; Mano, M.; et al. "Neuropilin-1 identifies a
subset of bone marrow Gr1-monocytes that can induce tumor vessel normalization and inhibit tumor growth". Cancer Research
72 24 (2012): 6371-6381.
10.1158/0008-5472.CAN-12-0762
- Eulalio, A.; Mano, M.; Ferro, M.D.; Zentilin, L.; Sinagra, G.; Zacchigna, S.; Giacca, M.. "Functional screening identifies
miRNAs inducing cardiac regeneration". Nature 492 7429 (2012): 376-381.
10.1038/nature11739
- Lovric, J.; Mano, M.; Zentilin, L.; Eulalio, A.; Zacchigna, S.; Giacca, M.. "Terminal differentiation of cardiac and skeletal
myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins". Molecular
Therapy 20 11 (2012): 2087-2097.
10.1038/mt.2012.144
- de Lorenzo, G.; Eichwald, C.; Schraner, E.M.; Nicolin, V.; Bortul, R.; Mano, M.; Burrone, O.R.; Arnoldi, F.. "Production of
in vivo-biotinylated rotavirus particles". Journal of General Virology 93 PART 7 (2012): 1474-1482.
10.1099/vir.0.040089-0
- Contin, R.; Arnoldi, F.; Mano, M.; Burrone, O.R.. "Rotavirus replication requires a functional proteasome for effective assembly
of viroplasms". Journal of Virology 85 6 (2011): 2781-2792.
10.1128/JVI.01631-10
- Girardini, J.; Napoli, M.; Piazza, S.; Rustighi, A.; Marotta, C.; Radaelli, E.; Capaci, V.; et al. "A Pin1/Mutant p53 Axis
Promotes Aggressiveness in Breast Cancer". Cancer Cell 20 1 (2011): 79-91.
10.1016/j.ccr.2011.06.004
- Eulalio, A.; Fröhlich, K.S.; Mano, M.; Giacca, M.; Vogel, J.. "A candidate approach implicates the secreted Salmonella effector
protein SpvB in P-body disassembly". PLoS ONE 6 3 (2011):
10.1371/journal.pone.0017296
- Murgia, S.; Falchi, A.M.; Mano, M.; Lampis, S.; Angius, R.; Carnerup, A.M.; Schmidt, J.; et al. "Nanoparticles from lipid-based
liquid crystals: Emulsifier influence on morphology and cytotoxicity". Journal of Physical Chemistry B 114 10 (2010):
3518-3525.
10.1021/jp9098655
- Trabulo, S.; Cardoso, A.L.; Mano, M.; de Lima, M.C.P.. "Cell-penetrating peptides-mechanisms of cellular uptake and generation
of delivery systems". Pharmaceuticals 3 4 (2010): 961-993.
10.3390/ph3040961
- Padari, K.; Koppel, K.; Lorents, A.; Hällbrink, M.; Mano, M.; Pedroso De Lima, M.C.; Pooga, M.. "S413-PV cell-penetrating
peptide forms nanoparticle-like structures to gain entry into cells". Bioconjugate Chemistry 21 4 (2010): 774-783.
10.1021/bc900577e
- Trabulo, S.; Mano, M.; Faneca, H.; Cardoso, A.L.; Duarte, S.; Henriques, A.; Paiva, A.; et al. "S413-PV cell penetrating
peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA". Journal of Gene Medicine
10 11 (2008): 1210-1222.
10.1002/jgm.1247
- Cervelli, T.; Palacios, J.A.; Zentilin, L.; Mano, M.; Schwartz, R.A.; Weitzman, M.D.; Giacca, M.. "Processing of recombinant
AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins". Journal of Cell
Science 121 3 (2008): 349-357.
10.1242/jcs.003632
- Mano, M.; Henriques, A.; Paiva, A.; Prieto, M.; Gavilanes, F.; Simões, S.; Pedroso de Lima, M.C.. "Interaction of S413-PV
cell penetrating peptide with model membranes: Relevance to peptide translocation across biological membranes". Journal
of Peptide Science 13 5 (2007): 301-313.
10.1002/psc.842
- Mano, M.; Henriques, A.; Paiva, A.; Prieto, M.; Gavilanes, F.; Simões, S.; Pedroso de Lima, M.C.. "Cellular uptake of S413-PV
peptide occurs upon conformational changes induced by peptide-membrane interactions". Biochimica et Biophysica Acta - Biomembranes
1758 3 (2006): 336-346.
10.1016/j.bbamem.2006.01.014
- Mano, M.; Teodósio, C.; Paiva, A.; Simões, S.; Pedroso De Lima, M.C.. "On the mechanisms of the internalization of S413-PV
cell-penetrating peptide". Biochemical Journal 390 2 (2005): 603-612.
10.1042/BJ20050577
- Simões, S.; Filipe, A.; Faneca, H.; Mano, M.; Penacho, N.; Düzgünes, N.; de Lima, M.P.. "Cationic liposomes for gene delivery".
Expert Opinion on Drug Delivery 2 2 (2005): 237-254.
10.1517/17425247.2.2.237
- Piedade, J.A.P.; Mano, M.; Pedroso de Lima, M.C.; Oretskaya, T.S.; Oliveira-Brett, A.M.. "Voltammetric behaviour of oligonucleotide
lipoplexes adsorbed onto glassy carbon electrodes". Journal of Electroanalytical Chemistry 564 1-2 (2004): 25-34.
10.1016/j.jelechem.2003.10.008
- Piedade, J.A.P.; Mano, M.; Pedroso De Lima, M.C.; Oretskaya, T.S.; Oliveira-Brett, A.M.. "Electrochemical sensing of the behaviour
of oligonucleotide lipoplexes at charged interfaces". Biosensors and Bioelectronics 20 5 (2004): 975-984.
10.1016/j.bios.2004.06.014
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