Identification
Personal identification
- Full name
- Ana Cristina Lopes Vasconcelos Ferreira
Citation names
- Ferreira, Ana
- Vasconcelos-Ferreira, Ana
Author identifiers
- Ciência ID
- 9D16-BDFB-BD29
- ORCID iD
- 0000-0002-8968-0641
Email addresses
- ac_ferreira@live.com.pt (Professional)
Addresses
- Center for Neurosciences and Cell Biology. Rua Larga, Faculdade de Medicina da Universidade de Coimbra, Pólo I, 2º Piso - Grupo de Vectores e Terapia Génica , 3004-504, Coimbra, Coimbra, Portugal (Professional)
Knowledge fields
- Natural sciences - Biological Sciences - Molecular Biology
- Natural sciences - Biological Sciences - Cell Biology
- Medical and Health Sciences - Basic Medicine - Neurosciences
- Medical and Health Sciences - Medical Biotechnology
Education
Degree | Classification | |
---|---|---|
2022/04
Concluded
|
Doutoramento Ciência Farmacêuticas (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
|
2014
Concluded
|
Laboratory animal science category B Course, under FELASA guidelines (Curso médio)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
|
2012
Concluded
|
Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Pharmacological activation of autophagy in Machado-Joseph disease" (THESIS/DISSERTATION)
|
17 |
2010
Concluded
|
Genética e Biotecnologia (Licenciatura)
Universidade de Trás-os-Montes e Alto Douro, Portugal
"Optimization of pollen DNA isolation from Honey" (THESIS/DISSERTATION)
|
15 |
2007
Concluded
|
Ciências e Tecnologias (Ensino secundário)
Escola Secundária Marco de Canaveses, Portugal
|
17 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2022/07/01 - Current | Researcher (Research) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2019/05/01 - 2022/06/30 | Researcher (Research) | Universidade de Coimbra, Portugal |
2017/02/01 - 2019/02/28 | Researcher (Research) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2009/09 - 2010/09 | Research Trainee (Research) | Universidade de Trás-os-Montes e Alto Douro, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2012/09 - 2022/04 | PhD student | CNC.IBILI, Portugal |
2020/04 - 2020/07 | Research fellow involved in setting up and certification of the laboratory for SARS-CoV-2 molecular testing at CNC-Viravector | Universidade de Coimbra, Portugal |
Universidade de Coimbra- Laboratório de Análises Clínicas, Portugal | ||
2010/09 - 2012/10 | Master Student | CNC.IBILI, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2019/05 - Current | BrainHealth 2020: Detecção precoce, neuro-modulação e terapias avançadas para neuropatologias
CENTRO-01-0145-FEDER-000008
Research Fellow
CNC.IBILI, Portugal
|
Ongoing
|
2017/02/01 - 2019/03 | ModelPolyQ - Advanced models of polyglutamine disorders (HD, SCA2, SCA3, SCA7)
02/BIM-JPND_ModelPolyQ/2016
Research Fellow
|
Contract
Designation | Funders | |
---|---|---|
2020/01 - 2023/12 | Centro de Inovação em Biomedicina e Biotecnologia
UIDB/04539/2020
Researcher
|
Ongoing
|
2018/07 - 2022/04 | Role of microRNA deregulation in Machado-Joseph Disease: On the development of a microRNA-based therapeutic strategy
PTDC/MED-NEU/32309/2017
Researcher
|
Ongoing
|
2018/07 - 2021/06 | Blocking neurodegeneration by spreading of gene silencers
PTDC/BTM-SAL/29716/2017
Researcher
|
|
2013/03 - 2016/12 | Towards the understanding of pathological protein processing and toxicity in Machado-Joseph Disease
E-Rare4/0003/2012
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference poster |
|
Journal article |
|
Newspaper article |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2021/02/18 | Importin-8 silencing prevents mutant ataxin-3 aggregation and delays Machado-Joseph Disease progression | 51.ª Reunião da Sociedade Portuguesa de Farmacologia 2021
Faculdade de Farmácia da Universidade de Lisboa (Lisboa)
|
2020/11/20 | Permanent inactivation of the ATXN3 gene: a possible therapeutic approach for Machado-Joseph Disease | 24ª Reunião da Sociedade Portuguesa Genética Humana
Sociedade Portuguesa Genética Humana (Portugal)
|
2019/11/14 | CRISPR-CAS9 systems targeting ATXN3 as therapeutic approaches for Machado-Joseph Disease. Flash Talk Presentation. | International Ataxia Research Conference (IARC 2019)
(Washington, DC, United States)
|
2019/11 | CRISPR-CAS9 systems targeting ATXN3 as therapeutic approaches for Machado-Joseph Disease | 2019 MJD International Research Conference
(Washington DC, United States)
|
2019/11 | Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph disease | 2019 MJD International Research Conference
(Washington, DC, United States)
|
2019/11 | Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph disease | International Research Ataxia Conference (IARC) 2019
(Washington, DC, United States)
|
2018/03 | Tailoring gene editing strategies for the treatment of Machado-Joseph disease | Portuguese Society of Movement Disorders (SPDMov 2018)
(Curia, Portugal)
|
2018/02 | Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph disease | XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
|
2018/02 | Pharmacological targeting of AMPK pathway as a therapeutic approach to polyglutamine diseases | XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
|
2018/02 | Repeated mesenchymal stromal treatment sustainably alleviates Machado-Joseph Disease | XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
|
2018/02 | The role of ageing in polyglutamine-induced neurodegeneration: a study in Machado-Joseph Disease models | XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
|
2018/02 | Nucleocytoplasmic transport proteins as modulators of Machado-Joseph Disease pathogenesis | XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
|
2017/02 | Investigating transcriptional modifications of the autophagy pathway in Machado-Joseph disease | XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
|
2017/02 | Is ageing the triggering factor in polyglutamine-induced neurodegeneration? A study in Machado-Joseph disease models | XLVII Reunião Anual SPF
(Coimbra, Portugal)
|
2017/01 | Is ageing the triggering factor in polyglutamine-induced neurodegeneration? A study in Machado-Joseph disease models | BEB DAY - Not So Usual Insights Into a PhD
Center for Neuroscience and Cell Biology (CNC), University of Coimbra (Coimbra, Portugal)
|
2016/02 | CORDYCEPIN: a pharmacological approach to modulate mutant ataxin-3 and it use as a potential therapeutic effect in Machado Joseph-disease | XLVI Reunião da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
|
2013/05 | Beclin-1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease | XIII Reunião da Sociedade Portuguesa de Neurociências
(Luso, Portugal)
|
2013/02 | Activation of autophagy mitigates neuropathology and motor impairments in mouse models of Machado-Joseph disease | XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
|
2010/10 | Optimization of pollen DNA isolation from Honey | IV Biojornadas
(Vila Real, Portugal)
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2015/12/17 - 2015/12/18 | Oral and poster presentations evaluation in XIII CNC Annual Meeting (2015/12/17 - 2015/12/18)
Meeting (Other)
|
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2015/07/03 - 2015/07/04 | Scientific retreat of research groups from the Center of Neurosciences and Cell Biology of the University of Coimbra: Neuroendocrinology
and Aging (PI Cláudia Cavadas) and Vectors and Gene Therapy (PI Luís Pereira de Almeida) (2015/07/03 - 2015/07/04)
Meeting (Co-organisor)
|
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2021/06/04 - 2021/06/04 | Invited lecture in society-targeted science outreach activity under the scope of the subject "Cidadania e Desenvolvimento",
12th grade.
Conference
|
"Conhecer a Doença de Machado-Joseph"
Escola Básica e Secundária das Flores, Portugal
|
2020/04 - 2020/06 | Research volunteer- task force for SARS-CoV2 testing
Other
|
COVID-19 research labs task force
Universidade de Coimbra- Laboratório de Análises Clínicas, Portugal
|
2018/03/20 - 2018/03/20 | Brain Awareness Week - Science communication activity
Conference
|
2018 Brain Awareness Week
Escola Secundária da Mealhada, Portugal
|
2016/11/18 - 2016/11/19 | 1st International Symposium - Brain Without Borders, held in Coimbra, Portugal. This event offered the opportunity to promote
discussion on fundamental and translational research in stem cell biology applied to the Central Nervous System.
Congress
|
Brain Without Borders
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
2016/09/30 - 2016/09/30 | European Researchers' Night 2016. Science communication activities at UC.
http://noitedosinvestigadores.pt/
Exhibition
|
European Researchers' Night 2016
Universidade de Coimbra, Portugal
|
2016/06/27 - 2016/07/01 | The CECAD Cologne Summer School provided business and managerial tools that are to be applied in innovative solutions for
important real-life aging-challenges, namely awareness about societal challenges, translational research, personalized medicine,
patent procedure as well as clinical trials requirements. This course was part of the European Institute of Innovation & Technology
(EIT Health) Campus programme.
Other
|
Entrepreneurial Introductory Translational Research (EITR)
Exzellenzcluster CECAD in der Universität zu Köln, Germany
|
Association member
Society Organization name | Role | |
---|---|---|
2022 - Current | Zero- Associação Sistema Terrestre Sustentável | |
2019 - Current | Sociedade Portuguesa de Neurociências |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2020/11/23 - 2020/12/04 | Biologia Celular: "Deteção de SARS-CoV-2 por RT-PCR" | (Licenciatura) | Universidade de Coimbra Faculdade de Farmácia, Portugal |
2020/09/17 - 2020/09/18 | Métodos e técnicas em Biologia Molecular: "Deteção de SARS-CoV-2 por RT-PCR" | Biologia (Licenciatura) | Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal |
2019/11/26 - 2019/11/26 | Regulação Celular: "Autophagia na doença de Machado-Joseph" | Mestrado em Investigação Biomédica (Mestrado) | Universidade de Coimbra Faculdade de Medicina, Portugal |
2017/09/26 - 2017/10/06 | Stereotaxic surgery: "Advanced anesthesia for surgical or prolonged procedures in mice and rats (skills)" | Course of Sciences in Laboratory animals (Outros) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2017/09/26 - 2017/10/06 | Stereotaxic surgery: "Principles of surgery (skills)" | Course of Sciences in Laboratory Animals | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2016/06/16 - 2016/06/16 | Advanced Therapies: "Pharmacological activation of autophagy in neurodegenerative disorders" | Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento) | Universidade de Coimbra, Portugal |
Interview (newspaper / magazine)
Activity description | Newspaper / Forum | |
---|---|---|
2022/01 | Interview within the scope of the published study "The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado Joseph disease". | Jornal "A Verdade" |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2013 - Current | Lab rotation students | Over 10 |
2020/08/01 - 2020/11/30 | Estabelicimento das condições para produção e purificação da proteína ataxina-3 | Tomás Sousa |
2020/08/01 - 2020/10/31 | Expressão e purificação da proteína ataxina-3 | Adriana Mata |
Distinctions
Award
2013 | Best Poster presentation- reSearch Coimbra in Health Sciences |
Other distinction
2019 | Travel bursary to attend the MJD Satellite Conference in Washington DC, USA.
MJD Foundation, Australia
|
2019 | Young investigator bursary to attend the International Ataxia Research Conference 2019 in Washington DC, USA. |
2016 | Travel bursary to attend the CECAD Short Course on Entrepreneurial Introductory Translational Research (EITR) |
2008 | Scholarship for the Integration in Scientific Research (BII)
Fundação para a Ciência e a Tecnologia, Portugal
|