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José da Trindade Vasconcelos Raposo Lopes Basílio. Completed the Licenciatura in Mestrado Integrado em Engenharia Biológica in 2009/09/01 by Universidade do Algarve and Master in Master in Tissue Engineering and Regenerative Medicine in 2013/09/01 by Fachhochschule Technikum Wien. Is Researcher in Associação para a Inovação e Desenvolvimento da FCT and Lecturer in Fachhochschule Technikum Wien. Published 21 articles in journals. Has received 1 awards and/or honors. Participates and/or participated as Research Fellow in 1 project(s) and Technical development in 4 project(s). Works in the area(s) of Exact Sciences with emphasis on Computer and Information Sciences with emphasis on Bioinformatics, Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology and Medical and Health Sciences with emphasis on Clinical Medicine with emphasis on Cardiac and Cardiovascular Systems.
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Identification

Personal identification

Full name
José da Trindade Vasconcelos Raposo Lopes Basílio

Citation names

  • Basílio, J.

Author identifiers

Ciência ID
AA12-7B63-A6EA
ORCID iD
0000-0001-7380-2942

Email addresses

  • jose.basilio@tecnico.ulisboa.pt (Professional)
  • zebasilio@gmail.com (Personal)

Telephones

Mobile phone
  • (+351) 912421953 (Personal)

Addresses

  • Schwarzspannierstrasse 17 3. Stock, Intitute Physiologie, Abteilung Gefässbiologie, Med Uni Wien, 1090, Vienna, Vienna, Austria (Professional)
  • Rua Alves Redol, 9, 1000-029, Lisboa, Lisboa, Portugal (Professional)
  • Avenida Almirante Reis 101 5.Esq, 1150-013, Lisboa, Lisboa, Portugal (Personal)

Knowledge fields

  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Clinical Medicine - Cardiac and Cardiovascular Systems

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
German Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1) Upper intermediate (B2)
Education
Degree Classification
2016/09/01 - 2018/09/01
Attended
 Master in Bioinformatics (Master)
Fachhochschule Campus Wien, Austria
2013/09/01
Concluded
 Master in Tissue Engineering and Regenerative Medicine (Master)
Fachhochschule Technikum Wien, Austria
2009/09/01
Concluded
 Mestrado Integrado em Engenharia Biológica (Licenciatura)
Universidade do Algarve, Portugal
Affiliation

Science

Category
Host institution 		Employer
2021/02/02 - Current Researcher (Research) Associação para a Inovação e Desenvolvimento da FCT, Portugal
Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
(...)
2013/11/01 - 2021/01/31 Contracted Researcher (Research) Medizinische Universität Wien, Austria
2012/09/01 - 2013/09/01 Research Trainee (Research) Medizinische Universität Wien, Austria
2010/04/01 - 2010/12/31 Contracted Researcher (Research) Forschungsinstitut für Orthopädietechnik, Austria

Teaching in Higher Education

Category
Host institution 		Employer
2018/05/01 - Current Lecturer (University Teacher) Fachhochschule Technikum Wien, Austria
2021/10/01 - 2022/02/28 Lecturer (University Teacher) Universidade de Lisboa Instituto Superior Técnico Campus Taguspark, Portugal
Universidade de Lisboa Instituto Superior Técnico Campus Taguspark, Portugal
2014/05/01 - 2020/05/01 Lecturer (University Teacher) Fachhochschule Technikum Wien, Austria
Projects

Grant

Designation Funders
2021 - 2024 Integrative single-cell analysis of chronically inflamed arteries to identify unknown cellular identities and their contribution to atherosclerosis
2020.09166.BD
 Fundação para a Ciência e a Tecnologia
2020/03 - 2020/03 TS9: Multiscale Systems Medicine: “Applying the System Medicine approach with bioinformatics tools in research”
ECOST-TRAINING_SCHOOL-CA15120-300320-112478
Technical development
European Cooperation in Science and Technology
2018/10 - 2018/10 Elucidating the role of IkB kinase 2 in atherothrombosis by multi-omics interactome analysis
42004
Research Fellow
European Cooperation in Science and Technology
2018/05 - 2018/05 TS4 - cyprus Systems Bioinformatics towards Network Medicine
ECOST-TRAINING_SCHOOL-CA15120-290518-100335
Technical development
European Cooperation in Science and Technology
2017/10 - 2017/10 Data Sharing Training School
ECOST-TRAINING_SCHOOL-CA15205-071117-085864
Technical development
European Cooperation in Science and Technology
2017/09 - 2017/09 TS2: Open MultiMed Training School “Computational Tools for Systems Medicine”
ECOST-TRAINING_SCHOOL-CA15120-260917-091935
Technical development
European Cooperation in Science and Technology
Outputs

Publications

Journal article
  1. Basílio, J.. "An Early Stage Researcher's Primer on Systems Medicine Terminology". Network and systems medicine (2021): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919422/?tool=EBI.
  2. Basílio, J.. "The inflammatory kinase IKKa phosphorylates and stabilizes c-Myc and enhances its activity.". Molecular cancer (2021): https://europepmc.org/articles/PMC7812655.
    10.1186/s12943-021-01308-8
  3. "MicroRNA Signatures in Plasma of Patients With Venous Thrombosis: A Preliminary Report.". The American journal of the medical sciences (2021): https://doi.org/10.1016/j.amjms.2020.12.002.
    10.1016/j.amjms.2020.12.002
  4. Basílio, J.. "Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis.". Atherosclerosis (2020): https://doi.org/10.1016/j.atherosclerosis.2020.06.005.
    10.1016/j.atherosclerosis.2020.06.005
  5. Basílio, J.. "Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine". Network and Systems Medicine (2020): http://dx.doi.org/10.1089/nsm.2020.0004.
    10.1089/nsm.2020.0004
  6. Basílio, José. "Comparative Interactome Analysis of Emerin, MAN1 and LEM2 Reveals a Unique Role for LEM2 in Nucleotide Excision Repair.". Cells (2020): https://europepmc.org/articles/PMC7072835.
    10.3390/cells9020463
  7. Basílio, José. "Altered platelet proteome in lupus anticoagulant (LA)-positive patients-protein disulfide isomerase and NETosis as new players in LA-related thrombosis.". Experimental & molecular medicine (2020): https://europepmc.org/articles/PMC7000701.
    10.1038/s12276-019-0358-4
  8. Basílio, José. "Comparative proteomics reveals unexpected quantitative phosphorylation differences linked to platelet activation state.". Scientific reports (2019): https://europepmc.org/articles/PMC6908631.
    10.1038/s41598-019-55391-5
  9. Basílio, José. "Purinergic P2Y2 receptors modulate endothelial sprouting". Cellular and Molecular Life Sciences (2019): http://dx.doi.org/10.1007/s00018-019-03213-2.
    10.1007/s00018-019-03213-2
  10. Basílio, José. "Community effort endorsing multiscale modelling, multiscale data science and multiscale computing for systems medicine". Briefings in Bioinformatics (2019): http://dx.doi.org/10.1093/bib/bbx160.
    10.1093/bib/bbx160
  11. Basílio, José. "Cell Type-Specific Roles of NF-¿B Linking Inflammation and Thrombosis". Frontiers in Immunology (2019): http://dx.doi.org/10.3389/fimmu.2019.00085.
    10.3389/fimmu.2019.00085
  12. Basílio, José. "Hypoxia/reperfusion predisposes to atherosclerosis". PLOS ONE (2018): http://dx.doi.org/10.1371/journal.pone.0205067.
    10.1371/journal.pone.0205067
  13. Basílio, José. "12(S)-HETE induces lymph endothelial cell retraction in�vitro by upregulation of SOX18". International Journal of Oncology (2018): http://dx.doi.org/10.3892/ijo.2018.4378.
    10.3892/ijo.2018.4378
  14. Basílio, José. "Androgen receptor dampens tissue factor expression via nuclear factor-¿B and early growth response protein 1". Journal of Thrombosis and Haemostasis (2018): http://dx.doi.org/10.1111/jth.13971.
    10.1111/jth.13971
  15. Basílio, José. "CD40L and TNF both activate the classical NF-¿B pathway, which is not required for the CD40L induced alternative pathway in endothelial cells". Biochemical and Biophysical Research Communications (2018): http://dx.doi.org/10.1016/j.bbrc.2017.11.160.
    10.1016/j.bbrc.2017.11.160
  16. Basílio, José. "Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation". Oncotarget (2016): http://dx.doi.org/10.18632/oncotarget.10191.
    10.18632/oncotarget.10191
  17. Basílio, José. "Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition". OncoImmunology (2016): http://dx.doi.org/10.1080/2162402x.2016.1164918.
    10.1080/2162402x.2016.1164918
  18. Basílio, José. "Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation". Scientific Reports (2016): http://dx.doi.org/10.1038/srep25171.
    10.1038/srep25171
  19. Basílio, José. "Sequence-function correlations and dynamics of ERG isoforms. ERG8 is the black sheep of the family". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (2016): http://dx.doi.org/10.1016/j.bbamcr.2015.10.023.
    10.1016/j.bbamcr.2015.10.023
  20. Basílio, José. "NF-κB contributes to MMP1 expression in breast cancer spheroids causing paracrine PAR1 activation and disintegrations in the lymph endothelial barrier in vitro". Oncotarget (2015): http://dx.doi.org/10.18632/oncotarget.5741.
    10.18632/oncotarget.5741
  21. Basílio J; Hoeth M; Holper-Schichl YM; Resch U; Mayer H; Hofer-Warbinek R; de Martin R. "TNFa-induced down-regulation of Sox18 in endothelial cells is dependent on NF-¿B.". (2013): http://europepmc.org/abstract/med/24269235.
    10.1016/j.bbrc.2013.11.030
Activities

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018/05/01 - Current Bioinformatics Bachelor in Biomedical Engineering (Bachelor) Fachhochschule Technikum Wien, Austria
2021/10/01 - 2022/02/28 Computational Biology Computational Biology (Mestrado) Universidade de Lisboa Instituto Superior Técnico Campus Taguspark, Portugal
2014/05/01 - 2020/05/01 Gene Regulation and Signal Transduction Tissue Engineering and Regenerative Medicine (Master) Fachhochschule Technikum Wien, Austria
Distinctions

Award

2012 Excellence Scholarship Award
Fachhochschule Technikum Wien, Austria