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José da Trindade Vasconcelos Raposo Lopes Basílio. Completed the Licenciatura in Mestrado Integrado em Engenharia Biológica in 2009/09/01 by Universidade do Algarve and Master in Master in Tissue Engineering and Regenerative Medicine in 2013/09/01 by Fachhochschule Technikum Wien. Is Researcher in Associação para a Inovação e Desenvolvimento da FCT and Lecturer in Fachhochschule Technikum Wien. Published 21 articles in journals. Has received 1 awards and/or honors. Participates and/or participated as Research Fellow in 1 project(s) and Technical development in 4 project(s). Works in the area(s) of Exact Sciences with emphasis on Computer and Information Sciences with emphasis on Bioinformatics, Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology and Medical and Health Sciences with emphasis on Clinical Medicine with emphasis on Cardiac and Cardiovascular Systems.
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Identificação

Identificação pessoal

Nome completo
José da Trindade Vasconcelos Raposo Lopes Basílio

Nomes de citação

  • Basílio, J.

Identificadores de autor

Ciência ID
AA12-7B63-A6EA
ORCID iD
0000-0001-7380-2942

Endereços de correio eletrónico

  • jose.basilio@tecnico.ulisboa.pt (Profissional)
  • zebasilio@gmail.com (Pessoal)

Telefones

Telemóvel
  • (+351) 912421953 (Pessoal)

Moradas

  • Schwarzspannierstrasse 17 3. Stock, Intitute Physiologie, Abteilung Gefässbiologie, Med Uni Wien, 1090, Vienna, Vienna, Áustria (Profissional)
  • Rua Alves Redol, 9, 1000-029, Lisboa, Lisboa, Portugal (Profissional)
  • Avenida Almirante Reis 101 5.Esq, 1150-013, Lisboa, Lisboa, Portugal (Pessoal)

Domínios de atuação

  • Ciências Exatas - Ciências da Computação e da Informação - Bioinformática
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Médicas e da Saúde - Medicina Clínica - Sistemas Cardíacos e Cardiovasculares

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Alemão Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B2)
Formação
Grau Classificação
2016/09/01 - 2018/09/01
Frequentou
 Master in Bioinformatics (Master)
Fachhochschule Campus Wien, Áustria
2013/09/01
Concluído
 Master in Tissue Engineering and Regenerative Medicine (Master)
Fachhochschule Technikum Wien, Áustria
2009/09/01
Concluído
 Mestrado Integrado em Engenharia Biológica (Licenciatura)
Universidade do Algarve, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/02/02 - Atual Investigador (Investigação) Associação para a Inovação e Desenvolvimento da FCT, Portugal
Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
(...)
2013/11/01 - 2021/01/31 Investigador Contratado (Investigação) Medizinische Universität Wien, Áustria
2012/09/01 - 2013/09/01 Estagiário de Investigação (Investigação) Medizinische Universität Wien, Áustria
2010/04/01 - 2010/12/31 Investigador Contratado (Investigação) Forschungsinstitut für Orthopädietechnik, Áustria

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/05/01 - Atual Leitor (Docente Universitário) Fachhochschule Technikum Wien, Áustria
2021/10/01 - 2022/02/28 Leitor (Docente Universitário) Universidade de Lisboa Instituto Superior Técnico Campus Taguspark, Portugal
Universidade de Lisboa Instituto Superior Técnico Campus Taguspark, Portugal
2014/05/01 - 2020/05/01 Leitor (Docente Universitário) Fachhochschule Technikum Wien, Áustria
Projetos

Bolsa

Designação Financiadores
2021 - 2024 Integrative single-cell analysis of chronically inflamed arteries to identify unknown cellular identities and their contribution to atherosclerosis
2020.09166.BD
 Fundação para a Ciência e a Tecnologia
2020/03 - 2020/03 TS9: Multiscale Systems Medicine: “Applying the System Medicine approach with bioinformatics tools in research”
ECOST-TRAINING_SCHOOL-CA15120-300320-112478
Desenvolvimento técnico
European Cooperation in Science and Technology
2018/10 - 2018/10 Elucidating the role of IkB kinase 2 in atherothrombosis by multi-omics interactome analysis
42004
Bolseiro de Investigação
European Cooperation in Science and Technology
2018/05 - 2018/05 TS4 - cyprus Systems Bioinformatics towards Network Medicine
ECOST-TRAINING_SCHOOL-CA15120-290518-100335
Desenvolvimento técnico
European Cooperation in Science and Technology
2017/10 - 2017/10 Data Sharing Training School
ECOST-TRAINING_SCHOOL-CA15205-071117-085864
Desenvolvimento técnico
European Cooperation in Science and Technology
2017/09 - 2017/09 TS2: Open MultiMed Training School “Computational Tools for Systems Medicine”
ECOST-TRAINING_SCHOOL-CA15120-260917-091935
Desenvolvimento técnico
European Cooperation in Science and Technology
Produções

Publicações

Artigo em revista
  1. Basílio, J.. "An Early Stage Researcher's Primer on Systems Medicine Terminology". Network and systems medicine (2021): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919422/?tool=EBI.
  2. Basílio, J.. "The inflammatory kinase IKKa phosphorylates and stabilizes c-Myc and enhances its activity.". Molecular cancer (2021): https://europepmc.org/articles/PMC7812655.
    10.1186/s12943-021-01308-8
  3. "MicroRNA Signatures in Plasma of Patients With Venous Thrombosis: A Preliminary Report.". The American journal of the medical sciences (2021): https://doi.org/10.1016/j.amjms.2020.12.002.
    10.1016/j.amjms.2020.12.002
  4. Basílio, J.. "Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis.". Atherosclerosis (2020): https://doi.org/10.1016/j.atherosclerosis.2020.06.005.
    10.1016/j.atherosclerosis.2020.06.005
  5. Basílio, J.. "Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine". Network and Systems Medicine (2020): http://dx.doi.org/10.1089/nsm.2020.0004.
    10.1089/nsm.2020.0004
  6. Basílio, José. "Comparative Interactome Analysis of Emerin, MAN1 and LEM2 Reveals a Unique Role for LEM2 in Nucleotide Excision Repair.". Cells (2020): https://europepmc.org/articles/PMC7072835.
    10.3390/cells9020463
  7. Basílio, José. "Altered platelet proteome in lupus anticoagulant (LA)-positive patients-protein disulfide isomerase and NETosis as new players in LA-related thrombosis.". Experimental & molecular medicine (2020): https://europepmc.org/articles/PMC7000701.
    10.1038/s12276-019-0358-4
  8. Basílio, José. "Comparative proteomics reveals unexpected quantitative phosphorylation differences linked to platelet activation state.". Scientific reports (2019): https://europepmc.org/articles/PMC6908631.
    10.1038/s41598-019-55391-5
  9. Basílio, José. "Purinergic P2Y2 receptors modulate endothelial sprouting". Cellular and Molecular Life Sciences (2019): http://dx.doi.org/10.1007/s00018-019-03213-2.
    10.1007/s00018-019-03213-2
  10. Basílio, José. "Community effort endorsing multiscale modelling, multiscale data science and multiscale computing for systems medicine". Briefings in Bioinformatics (2019): http://dx.doi.org/10.1093/bib/bbx160.
    10.1093/bib/bbx160
  11. Basílio, José. "Cell Type-Specific Roles of NF-¿B Linking Inflammation and Thrombosis". Frontiers in Immunology (2019): http://dx.doi.org/10.3389/fimmu.2019.00085.
    10.3389/fimmu.2019.00085
  12. Basílio, José. "Hypoxia/reperfusion predisposes to atherosclerosis". PLOS ONE (2018): http://dx.doi.org/10.1371/journal.pone.0205067.
    10.1371/journal.pone.0205067
  13. Basílio, José. "12(S)-HETE induces lymph endothelial cell retraction in�vitro by upregulation of SOX18". International Journal of Oncology (2018): http://dx.doi.org/10.3892/ijo.2018.4378.
    10.3892/ijo.2018.4378
  14. Basílio, José. "Androgen receptor dampens tissue factor expression via nuclear factor-¿B and early growth response protein 1". Journal of Thrombosis and Haemostasis (2018): http://dx.doi.org/10.1111/jth.13971.
    10.1111/jth.13971
  15. Basílio, José. "CD40L and TNF both activate the classical NF-¿B pathway, which is not required for the CD40L induced alternative pathway in endothelial cells". Biochemical and Biophysical Research Communications (2018): http://dx.doi.org/10.1016/j.bbrc.2017.11.160.
    10.1016/j.bbrc.2017.11.160
  16. Basílio, José. "Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation". Oncotarget (2016): http://dx.doi.org/10.18632/oncotarget.10191.
    10.18632/oncotarget.10191
  17. Basílio, José. "Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition". OncoImmunology (2016): http://dx.doi.org/10.1080/2162402x.2016.1164918.
    10.1080/2162402x.2016.1164918
  18. Basílio, José. "Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation". Scientific Reports (2016): http://dx.doi.org/10.1038/srep25171.
    10.1038/srep25171
  19. Basílio, José. "Sequence-function correlations and dynamics of ERG isoforms. ERG8 is the black sheep of the family". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (2016): http://dx.doi.org/10.1016/j.bbamcr.2015.10.023.
    10.1016/j.bbamcr.2015.10.023
  20. Basílio, José. "NF-κB contributes to MMP1 expression in breast cancer spheroids causing paracrine PAR1 activation and disintegrations in the lymph endothelial barrier in vitro". Oncotarget (2015): http://dx.doi.org/10.18632/oncotarget.5741.
    10.18632/oncotarget.5741
  21. Basílio J; Hoeth M; Holper-Schichl YM; Resch U; Mayer H; Hofer-Warbinek R; de Martin R. "TNFa-induced down-regulation of Sox18 in endothelial cells is dependent on NF-¿B.". (2013): http://europepmc.org/abstract/med/24269235.
    10.1016/j.bbrc.2013.11.030
Atividades

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2018/05/01 - Atual Bioinformatics Bachelor in Biomedical Engineering (Bachelor) Fachhochschule Technikum Wien, Áustria
2021/10/01 - 2022/02/28 Computational Biology Computational Biology (Mestrado) Universidade de Lisboa Instituto Superior Técnico Campus Taguspark, Portugal
2014/05/01 - 2020/05/01 Gene Regulation and Signal Transduction Tissue Engineering and Regenerative Medicine (Master) Fachhochschule Technikum Wien, Áustria
Distinções

Prémio

2012 Excellence Scholarship Award
Fachhochschule Technikum Wien, Áustria