???global.info.a_carregar???
Hélder José Couto Oliveira completed a PhD in Sustainable Chemistry in 2018 from the University of Porto, a Master's in Biochemistry in 2014 and a Degree in Biochemistry in 2012 from the same institution. He is currently a CEEC Researcher hired by LAQV-REQUIMTE and invited adjunct professor at the Escola Superior de Saúde of the Polytechnic Institute of Porto. He is the Principal Investigator of the project AnthoE.Flos (2022.01014.PTDC). He participated in several scientific, academic and social projects, including the presidency of the Portuguese Biochemistry Students Association from 2014 to 2018 and the development of scientific work in China, at Wuhan Polytechnic University. His area of expertise involves the study of the bioavailability and bioactivity of polyphenols (anthocyanins). He is member of the executive board of Associação Nacional de Bioquímicos. He speaks fluent English and has a third degree of Chinese language and culture. He has been involving in the supervision of several undergraduates students. He is also responsible for the creation and maintenance of three scientific group websites: www.foodphenolab.com; www.groupepolyphenols.com; www.anthoeflos.com.
Read full resume ↓
Identification

Personal identification

Full name
Hélder José Couto Oliveira
Date of birth
1991/03/20
Gender
Male

Citation names

  • Oliveira, Hélder

Author identifiers

Ciência ID
AB10-2C5D-8CA8
ORCID iD
0000-0002-8256-2968

Email addresses

  • helder.oliveira@fc.up.pt (Professional)
  • hjo@ess.ipp.pt (Professional)

Telephones

Mobile phone
  • 910855177 (Personal)

Addresses

  • Faculdade de Ciências da Universidade do Porto. Rua do Campo Alegre nº 687, 4169-007, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Exact Sciences - Chemical Sciences
  • Agrarian Sciences - Agriculture, Forestry and Fisheries - Agriculture

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Chinese Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2018
Concluded
 Química Sustentável (Doutoramento)
Major in Food Chemistry and Biochemistry
Universidade do Porto Faculdade de Ciências, Portugal
"The Biochemistry behind anthocyanins bioavailability" (THESIS/DISSERTATION)
 Unanimously Approved (17/20 curricular year)
2014
Concluded
 Bioquímica (Mestrado)
Major in Sem especialização
Universidade do Porto Faculdade de Ciências, Portugal
"Biodisponibilidade de antocianinas do vinho de mesa" (THESIS/DISSERTATION)
 17/20
2012
Concluded
 Bioquimica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Propriedades antitumorais do Vinho do Porto" (THESIS/DISSERTATION)
 16/20
Affiliation

Science

Category
Host institution 		Employer
2022/01/01 - Current Contracted Researcher (Research) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2021/06/01 - 2022/10/31 Science and Technology Management Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2019/01/01 - 2021/05/30 Contracted Researcher (Research) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2015/04/01 - 2015/10/31 Researcher (Research) Wuhan Polytechnic University, China
2013/09/01 - 2015/02/28 Research Trainee (Research) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018/09/15 - Current Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2020/02/01 - 2021/07/31 Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal

Others

Category
Host institution 		Employer
2015/03/01 - 2018/12/31 Bolseiro de Doutoramento Universidade do Porto Faculdade de Ciências, Portugal
Projects

Grant

Designation Funders
2025/01/01 - Current FLORA.MED - Exploring the Therapeutic Potential of Edible Flowers Rich in Anthocyanins in Metabolic Disease
2023.11612.PEX
Principal investigator
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/01 - Current AnthoE.Flos -Anthocyanin-Rich Edible Flowers: towards an emerging, more sustainable and healthier diet
2022.01014.PTDC
Principal investigator
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 FCT- Fundação para o Desenvolvimento e Tecnologia
Ongoing

Contract

Designation Funders
2013 - Current Funding of Strategic Projects with Public Interest promoted by Associated Laboratories and RD Units - 2013 - COMPETE.
PEst-C/QUI/UI0081/2013
Researcher
Universidade do Porto Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Associated Laboratory for Green Chemistry - Clean Technologies and Processes
LA/P/0008/2020
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade de Évora, Portugal

Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021 - 2024 MONET- Unravelling microbiota-gut-axis paintings in obesity-associated neuroinflammation: the blackberry signature study
PTDC/BAA-AGR/7419/2020
Researcher
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017/04 - 2021/12/31 IBERPHENOL – Research cooperative within the scope of polyphenols and its industrial applications.
0377_IBERPHENOL_6_E
PhD Student Fellow
2017/01/01 - 2021/12/31 Promoting Agri-food and Forestry Stakeholder Engagement for Knowledge Transfer and SMARTAgriFor partnerships.
NORTE-01-0246-FEDER-000023
Researcher
REQUIMTE LAQV Porto, Portugal
Ongoing
2019/01/01 - 2021/06/01 WINPUT – Wine-inspired synthesis of blue pyranoflavyliums for topical Photodynamic Therapy
PTDC/QUI-OUT/29013/2017
Researcher
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos
UID/QUI/50006/2019
Universidade do Porto Faculdade de Ciências, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/05/01 - 2019/11/01 ANTHO4SKIN ¿ Novos derivados antociânicos para aplicações tecnológicas na indústria cosmética.
PTDC/AGR-TEC/3078/2014
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/06/01 - 2019/01/01 VINE&WINE RESIDUES – Unlimited resources of high-value polyphenols for application into Functional Foods.
PTDC/AGR- TEC/2789/2014
PhD Student Fellow
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2014/01/01 - 2016/01/01 Collaborative research for the development on novel technologies for stabilizing natural anthocyanin pigments and their applications
Ref. 441.00
Researcher
Sino-Portuguese Programme, China
 Sino-Portuguese Programme
Ongoing
2015/05 - 2015/10 National Program for International S&T Cooperation Projects
2014DFG32310
PhD Student Fellow
Ministry of Science and Technology of the People's Republic of China
Concluded
2013/09/01 - 2015/03/31 “VINOFLAVO – Red wine flavonoids: bioavailability and biological properties.”
PTDC/AGR-TEC/2227/2012
PhD Student Fellow
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2019 - Current UMBRELLA: Wine by-products to treat skin diseases. Cheap and innovative solutions.
UMBRELLA
 Fundo de capital de risco MustardSeedMaze
2017 - 2018 Nano4nutrition: Nanotechnology approach for targeted absorption of nutraceuticals towards a human healthy nutrition
Not applied
PhD Student Fellow
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Rede de Química e Tecnologia Laboratório Associado para a Química Verde
Concluded
Outputs

Publications

Book chapter
  1. Oliveira, Hélder; Pérez-Gregorio, R.; Fernandes, I.; Soares, S.; Freitas, V.; Dias, R.. "New Trends from Plant Secondary Metabolism in the Pharmaceutical Industry". In Natural Secondary Metabolites, 779-822. Springer International Publishing, 2023.
    Published • 10.1007/978-3-031-18587-8_25
  2. Fernandes, Ana; Oliveira, Hélder; Teixeira, Natércia; Mateus, Nuno; de Freitas, Victor. "Extraction efficiency of phenolic compounds by bioconversion and their implication on their biological effects". In Technologies to Recover Polyphenols from AgroFood By-products and Wastes, 271-300. Elsevier, 2022.
    Published • 10.1016/b978-0-323-85273-9.00003-x
  3. Fernandes, Iva; Oliveira, Hélder; Marques, Cláudia; Faria, Ana; Calhau, Conceição; Mateus, Nuno; De Freitas, Victor. "Chapter 7. Dietary anthocyanins". In Dietary polyphenols: their metabolism and health effects. United States: Willey-Blackwell, Oxford, 2020.
    Published
Conference poster
  1. Martoccia, Manuel; Oliveira, Hélder; Aceto, Maurizio; Disca, Vincenzo; Bordiga, Matteo; Coïsson, Jean Daniel. "Foliar application of sodium selenate: effects on bioactive compounds and quality of raspberry (Rubus idaeus L.).". Paper presented in 11th International Symposium on RECENT ADVANCES IN FOOD ANALYSIS, 2024.
  2. Oliveira, Hélder; Teixeira, Margarida; Freitas, Victor; Mateus, Nuno. "Comparison between the Absorption of Anthocyanins from Edible Flowers Using Two Intestinal Models: Caco-2 and Caco-2/HT29-MTX". Paper presented in 8th International Conference on Food Digestion, 2024.
  3. Teixeira, Margarida; Mateus, Nuno; Freitas, Victor; Oliveira, Hélder. "Anthocyanin Bioavailability from Edible Flowers: Gastrotechnic and in vitro Approaches". Paper presented in 8th International Conference on Food Digestion, 2024.
  4. Oliveira, Hélder; Lorenzo De Luca; Bordiga, Matteo; Victor de Freitas; Nuno Mateus. "New insights on the isolation of anthocyanins from complex matrices using cationexchange solid-phase extraction". Paper presented in 13º Encontro Nacional de Cromatografia, 2023.
  5. Tao, Wen; Ana Fernandes; He, Jingren; Isabel Ferreira; Nuno Mateus; Victor Freitas; Oliveira, Hélder. "Red cabbage anthocyanins-loaded nanoparticles comprising plant- based proteins and polysaccharides: stability, antioxidant capacity, and bioaccessibility". Paper presented in XXVII Encontro Luso Galego de Química, 2023.
  6. Oliveira, Hélder; Teixeira, Margarida; Tao, Wen; Freitas, Victor; Mateus, Nuno; Margarida Teixeira; Tao, Wen; Victor de Freitas; Nuno Mateus. Corresponding author: Oliveira, Hélder. "Assessment of anthocyanin-rich edible flowers bioaccessibility using food processing approaches". Paper presented in Food Bioactives & Health, 2023.
  7. Teixeira, Margarida; Mateus, Nuno; Freitas, Victor; Oliveira, Hélder. Corresponding author: Oliveira, Hélder. "Edible flowers rich in anthocyanins: biochemistry and biotechnology towards an emerging, healthier, and sustainable diet". Paper presented in XXVIII Encontro Nacional da SPQ, 2023.
  8. Oliveira, Hélder; Teixeira, Margarida; Tao, Wen; Freitas, Victor; Mateus, Nuno. Corresponding author: Oliveira, Hélder. "Bioaccessibility of anthocyanins from edible flowers using gastrotechnic approaches". Paper presented in International Conference on Polyphenols, 2023.
  9. Oliveira, Hélder. "Edible Flowers as a re-emerging healthy food option: the case of Gardenia jasminoides Ellis, from absorption to antiproliferative and anti-inflammatory properties.". Paper presented in 1st FEBS Redox Medicine Workshop, 2023.
  10. Oliveira, Hélder. "Dietary polyglycosylated anthocyanins, the smart option? Towards their stability and bioavailability". Paper presented in XVIth Encontro Química dos Alimentos, 2022.
  11. Oliveira, Hélder. "Dietary polyglycosylated anthocyanins, the smart option? Towards their stability and bioavailability". Paper presented in 10th International Conference on Polyphenols and Health, 2022.
  12. Melanie Fonte; Natália Tassi; Oliveira, Hélder; Fernandes, Iva; Mateus, Nuno; Ferraz, Ricardo; Maria João Sinde Monteiro Pinto de Araújo; Gomes, Paula; Teixeira, Catia. Corresponding author: Teixeira, Catia. "4,9-diaminoacridines and 4-aminoacridines as potential antiproliferative hits". Paper presented in The 7th International Electronic Conference on Medicinal Chemistry, 2021.
  13. Patrícia Correia; Oliveira, Hélder; et al.. "Exploring the colour and bioactivity of anthocyanin related structures towards skin healthcare - bridging food and therapeutics". Paper presented in XXX International Conference on Polyphenols, Turku, Finland, 2021.
  14. Iva Fernandes; Ana Faria; Claúdia Marques; Hélder Oliveira; et al.. "Pharmacokinetics of table and Port red wine anthocyanins: a crossover trial in healthy men". Paper presented in 1o Congresso da Rede das Instituições de Ensino Superior para a Salvaguarda da Dieta Mediterrânica (RIESDM), 2021.
  15. Ribeiro, Carolina; Oliveira, Hélder; De Freitas, Victor; Mateus, Nuno; Oliveira, Joana; Silva, Carla; Pereira, Clara; Fernandes, Iva. "Cosmetotextiles: A strategy for the application of anthocyanins from industrial waste". Paper presented in Iberphenol - International Conference, 2020.
  16. Oliveira, Hélder; Han, Fuliang; Iva Fernandes; Victor de Freitas; Nuno Mateus. "New insights on the bioavailability of anthocyanins: from structural role to molecular mechanisms". Paper presented in International Conference on Polyphenols and Health, 2019.
  17. Fernandes, Iva; Oliveira, Joana; Oliveira, Hélder; Correia, Patrícia; Araújo, Paula; Ana Rita Pereira; Bessa, Lucinda J.; et al. "Colour and bioactivity of anthocyanin derivatives towards skin healthcare - bridging food and therapeutics". Paper presented in International Conference on Polyphenols and Health, 2019.
  18. Iva Fernandes; Joana Oliveira; Hélder Oliveira; et al.. "Exploring the colour and bioactivity of anthocyanin derivatives towards skin healthcare – bridging food and therapeutics". Paper presented in th International Conference on Polyphenols and Health, Kobe, Japan, 2019.
  19. Patrícia, Correia; Oliveira, Hélder; Iva Fernandes; Victor de Freitas; Nuno Mateus. "Physical and Chemical Characterization of anthocyanins from Purple-fleshed Sweet Potato". Paper presented in XXIV Encontro Luso-Galego de Química, 2019.
  20. Ana Rita Pereira; Inês Rocha; Paula Araújo; Hélder Oliveira; et al.. "Interaction between Zinc oxide and anthocyanins for the stabilization of their bluish color towards skincare applications". Paper presented in XXVI Encontro Nacional da Sociedade Portuguesa de Química, 2019.
  21. Oliveira, Hélder; Fernandes, Iva; De Freitas, Victor; Mateus, Nuno. "Gastrointestinal absorption of anthocyanins: a molecular approach". Paper presented in XXIVth Encontro Luso Galego de Química, Porto, Portugal, 2018.
  22. Oliveira, Hélder; Fernandes, Iva; De Freitas, Victor; Mateus, Nuno. "Gastrointestinal absorption of anthocyanins: a molecular approach". Paper presented in XIV Encontro de Química dos Alimentos, Viana do Castelo, Portugal, 2018.
  23. Oliveira, Hélder; Fernandes, Iva; De Freitas, Victor; Mateus, Nuno. "Physical and Chemical characterization of anthocyanins from purple-fleshed sweet Potato". Paper presented in XIV Encontro de Química dos Alimentos, Viana do Castelo, Portugal, 2018.
  24. Fernandes, Iva; Évora, A.; Oliveira, Hélder; Ribeiro, C.; De Freitas, Victor; Mateus, Nuno. "Anthocyanins as potential skincare ingredients". Paper presented in 2nd conference on Food Bioactives and Health, Lisbon, Portugal, 2018.
  25. Oliveira, Hélder; Fernandes, Iva; De Freitas, Victor; Mateus, Nuno. "Ultrahigh-Pressure Liquid Chromatography with fluorescent detection (UPLC-FLD) method for the identification of anthocyanins from Purple Sweet Potato". Paper presented in 10º Encontro Nacional de Cromatografia, Bragança, 2017.
  26. Oliveira, Hélder; Perez-Gregório, Rosa; Fernandes, Iva; De Freitas, Victor; He, Jingren; Mateus, Nuno. "Characterization of protein and anthocyanin extracts from Purple-Fleshed Sweet Potato: on a journey to understand their interactions". Paper presented in XXII Encontro Luso-Galego de Química, Bragança, Portugal, 2016.
  27. Oliveira, Hélder; Fernandes, Iva; De Freitas, Victor; He, Jingren; Mateus, Nuno. "Gastric transport studies and breast cancer apoptosis mediated cell-death by Malvidin-3-O-glucoside and their derivatives". Paper presented in 5th International Iberian Biophysics Congress, Porto Portugal, 2016.
  28. Oliveira, Hélder; Fernandes, Iva; Brás, Natércia F.; Faria, A.; De Freitas, Victor; Calhau, Conceição; Mateus, Nuno. "On the gastric absorption of red wine anthocyanins". Paper presented in 8th International Workshop on Anthocyanins, Montpellier, France, 2015.
  29. Fernandes, Iva; Faria, A.; Oliveira, Hélder; Norberto, S.; De Freitas, Victor; Calhau, Conceição; Mateus, Nuno. "Anthocyanin bioavailability: a multiple-approach study". Paper presented in International Conference on Polyphenols, Nagoya, Japan, 2014.
  30. Oliveira, Hélder. "On the anti-tumoral properties of Port Wine polyphenols and their bioavailability.". Paper presented in IJUP, 2014.
  31. Iva Luzia Reis Fernandes; Oliveira, Hélder; Mariana Araújo; Victor de Freitas; Pedro Sá; Nuno Filipe da Cruz Baptista Mateus. "Anti-tumoral properties of Port Wine polyphenols". Paper presented in 11º Encontro de Química dos Alimentos, 2012, 2012.
Journal article
  1. Jaouhari, Yassine; Ferreira-Santos, Pedro; Disca, Vincenzo; Oliveira, Hélder; Martoccia, Manuel; Travaglia, Fabiano; Gullón, Beatriz; et al. "Carbohydrases treatment on blueberry pomace: Influence on chemical composition and bioactive potential". LWT 206 (2024): 116573. http://dx.doi.org/10.1016/j.lwt.2024.116573.
    10.1016/j.lwt.2024.116573
  2. Liu, Yang; Fernandes, Iva; Mateus, Nuno; Oliveira, Hélder; Han, Fuliang. "The Role of Anthocyanins in Alleviating Intestinal Diseases: A Mini Review". Journal of Agricultural and Food Chemistry 72 11 (2024): 5491-5502. http://dx.doi.org/10.1021/acs.jafc.3c07741.
    10.1021/acs.jafc.3c07741
  3. Margarida Teixeira; Lorenzo De Luca; Ana Faria; Matteo Bordiga; Victor de Freitas; Nuno Mateus; Oliveira, Hélder. Corresponding author: Oliveira, Hélder. "First Insights on the Bioaccessibility and Absorption of Anthocyanins from Edible Flowers: Wild Pansy, Cosmos, and Cornflower". Pharmaceuticals 17 191 (2024):
    Open access • Published
  4. Teixeira, Margarida; Tao, Wen; Fernandes, Ana; Faria, Ana; Ferreira, Isabel M.P.L.V.O.; He, Jingren; de Freitas, Victor; Mateus, Nuno; Oliveira, Hélder. Corresponding author: Oliveira, Hélder. "Anthocyanin-rich edible flowers, current understanding of a potential new trend in dietary patterns.". Trends in Food Science & Technology 138 (2023): 708-725. http://dx.doi.org/10.1016/j.tifs.2023.07.010.
    10.1016/j.tifs.2023.07.010
  5. Câmara, José S.; Locatelli, Monica; Pereira, Jorge A. M.; Oliveira, Hélder; Arlorio, Marco; Fernandes, Iva; Perestrelo, Rosa; Freitas, Victor; Bordiga, Matteo. "Behind the Scenes of Anthocyanins—From the Health Benefits to Potential Applications in Food, Pharmaceutical and Cosmetic Fields". Nutrients 14 23 (2022): 5133. http://dx.doi.org/10.3390/nu14235133.
    10.3390/nu14235133
  6. Jiang, Tian; Ye, Shuxin; Liao, Wei; Wu, Muci; He, Jingren; Mateus, Nuno; Oliveira, Hélder. Corresponding author: Oliveira, Hélder. "The botanical profile, phytochemistry, biological activities and protected-delivery systems for purple sweet potato (Ipomoea batatas (L.) Lam.): An up-to-date review". Food Research International 161 (2022): 111811. http://dx.doi.org/10.1016/j.foodres.2022.111811.
    10.1016/j.foodres.2022.111811
  7. Silva, Sara; Costa, Eduardo M.; Oliveira, Hélder; Freitas, Vitor De; Morais, Rui M.; Calhau, Conceição; Pintado, Manuela. "Impact of a Purified Blueberry Extract on In Vitro Probiotic Mucin-Adhesion and Its Effect on Probiotic/Intestinal Pathogen Systems". Molecules 27 20 (2022): 6991. http://dx.doi.org/10.3390/molecules27206991.
    10.3390/molecules27206991
  8. He, Jingren; Ye, Shuxin; Correia, Patrícia; Fernandes, Iva; Zhang, Rui; Wu, Muci; Freitas, Victor; Mateus, Nuno; Oliveira, Hélder. "Dietary polyglycosylated anthocyanins, the smart option? A comprehensive review on their health benefits and technological applications". Comprehensive Reviews in Food Science and Food Safety (2022): http://dx.doi.org/10.1111/1541-4337.12970.
    10.1111/1541-4337.12970
  9. Zhang, Rui; Zhang, Qian; Oliveira, Hélder; Mateus, Nuno; Ye, Shuxin; Jiang, Sijia; He, Jingren; Wu, Muci. Corresponding author: Oliveira, Hélder. "Preparation of nanoliposomes loaded with anthocyanins from grape skin extracts: stability, gastric absorption and antiproliferative properties". Food & Function 13 21 (2022): 10912-10922. http://dx.doi.org/10.1039/d2fo02008d.
    10.1039/d2fo02008d
  10. Tao, Wen; An, Xiaoyu; Guo, Ziqi; Yang, Ning; Wu, Muci; Oliveira, Hélder; Zhang, Rui; He, Jingren. "Structural characterization, acute toxicity assessment and protective effects of selenylated apple pectin on dextran sulfate sodium-induced ulcerative colitis". Food & Function 13 13 (2022): 7320-7332. http://dx.doi.org/10.1039/d1fo04189d.
    10.1039/d1fo04189d
  11. Oliveira, Hélder; Araújo, Paula; Pereira, Ana Rita; Mateus, Nuno; de Freitas, Victor; Oliveira, Joana; Fernandes, Iva. "Photoactivated cell-killing amino-based flavylium compounds". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-01485-y.
    10.1038/s41598-021-01485-y
  12. Marcelo D. Catarino; Iva Fernandes; Hélder Oliveira; Mylene Carrascal; Rita Ferreira; Artur M. S. Silva; Maria Teresa Cruz; Nuno Mateus; Susana M. Cardoso. "Antitumor Activity of Fucus vesiculosus-Derived Phlorotannins through Activation of Apoptotic Signals in Gastric and Colorectal Tumor Cell Lines". International Journal of Molecular Sciences 22 14 (2021): 7604-7604. https://doi.org/10.3390/ijms22147604.
    10.3390/ijms22147604
  13. Patrícia Correia; Paula Araújo; Carolina Ribeiro; Hélder Oliveira; Ana Rita Pereira; Nuno Mateus; Victor de Freitas; et al. "Anthocyanin-Related Pigments: Natural Allies for Skin Health Maintenance and Protection". Antioxidants 10 7 (2021): 1038-1038. https://doi.org/10.3390/antiox10071038.
    10.3390/antiox10071038
  14. Patrícia Correia; Hélder Oliveira; Paula Araújo; Natércia F. Brás; Ana Rita Pereira; Joana Moreira; Victor de Freitas; et al. "The Role of Anthocyanins, Deoxyanthocyanins and Pyranoanthocyanins on the Modulation of Tyrosinase Activity: An In Vitro and In Silico Approach". International Journal of Molecular Sciences 22 12 (2021): 6192-6192. https://doi.org/10.3390/ijms22126192.
    10.3390/ijms22126192
  15. Oliveira, Hélder; Patricia Correia; Lucinda Bessa; Marta Guimarães; Nuno Mateus; Victor de Freitas; Paula Gameiro; Luís Cruz; Iva Fernandes. "Cyanidin-3-glucoside lipophilic conjugates for topical application: Tuning the antimicrobial activities with fatty acid chain length". Processes 9 (2021): 340. https://doi.org/10.3390/pr9020340.
    Open access • Published • 10.3390/pr9020340
  16. Hélder Oliveira; Patrícia Correia; Ana Rita Pereira; Paula Araújo; Nuno Mateus; Victor de Freitas; Joana Oliveira; Iva Fernandes. "Exploring the Applications of the Photoprotective Properties of Anthocyanins in Biological Systems". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21207464.
    10.3390/ijms21207464
  17. Oliveira, Hélder; Fernandes, Ana; F. Brás, Natércia; Mateus, Nuno; de Freitas, Victor; Fernandes, Iva. "Anthocyanins as Antidiabetic Agents—In Vitro and In Silico Approaches of Preventive and Therapeutic Effects". Molecules 25 17 (2020): 3813. http://dx.doi.org/10.3390/molecules25173813.
    Published • 10.3390/molecules25173813
  18. Dias, Ricardo; Oliveira, Helder; Fernandes, Iva; Simal-Gandara, Jesus; Perez-Gregorio, Rosa. "Recent advances in extracting phenolic compounds from food and their use in disease prevention and as cosmetics". Critical Reviews in Food Science and Nutrition (2020): 1-22. http://dx.doi.org/10.1080/10408398.2020.1754162.
    10.1080/10408398.2020.1754162
  19. Han, Fuliang; Oliveira, Hélder; Brás, Natércia F.; Fernandes, Iva; Cruz, Luís; De Freitas, Victor; Mateus, Nuno. "In vitro gastrointestinal absorption of red wine anthocyanins – Impact of structural complexity and phase II metabolization". Food Chemistry 317 (2020): 126398. http://dx.doi.org/10.1016/j.foodchem.2020.126398.
    Published • 10.1016/j.foodchem.2020.126398
  20. Zhang, Rui; Zhou, Lan; Li, Jia; Oliveira, Hélder; Yang, Ning; Jin, Weiping; Zhu, Zhenzhou; Li, Shuyi; He, Jingren. "Microencapsulation of anthocyanins extracted from grape skin by emulsification/internal gelation followed by spray/freeze-drying techniques: Characterization, stability and bioaccessibility". LWT (2020): 109097. http://dx.doi.org/10.1016/j.lwt.2020.109097.
    Published • 10.1016/j.lwt.2020.109097
  21. Oliveira, Hélder; Perez-Gregório, Rosa; de Freitas, Victor; Mateus, Nuno; Fernandes, Iva. "Comparison of the in vitro gastrointestinal bioavailability of acylated and non-acylated anthocyanins: Purple-fleshed sweet potato vs red wine". Food Chemistry 276 (2019): 410-418. http://dx.doi.org/10.1016/j.foodchem.2018.09.159.
    Published • 10.1016/j.foodchem.2018.09.159
  22. Oliveira, Hélder; Basílio, Nuno; Pina, Fernando; Fernandes, Iva; De Freitas, Victor; Mateus, Nuno. "Purple-Fleshed Sweet Potato acylated anthocyanins: equilibrium network and photophysical properties.". Food Chemistry 288 (2019): 386-394. https://doi.org/10.1016/j.foodchem.2019.02.132.
    Published • j.foodchem.2019.02.132
  23. Oliveira, Hélder; Roma-Rodrigues, Catarina; Santos, Ana; Veigas, Bruno; Brás, Natércia; Faria, Ana; Calhau, Conceição; et al. "GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-018-37283-2.
    Open access • http://dx.doi.org/10.1038/s41598-018-37283-2
  24. Oliveira, Hélder; Cai, Xiaoshuang; Zhang, Qian; de Freitas, Victor; Mateus, Nuno; He, Jingren; Fernandes, Iva. "Gastrointestinal absorption, antiproliferative and anti-inflammatory effect of the major carotenoids of Gardenia jasminoides Ellis on cancer cells". Food & Function 8 4 (2017): 1672-1679. http://dx.doi.org/10.1039/c7fo00091j.
    Published • 10.1039/c7fo00091j
  25. Pereira, Ricardo N.; Rodrigues, Rui M.; Genisheva, Zlatina; Oliveira, Hélder; de Freitas, Victor; Teixeira, José A.; Vicente, António A.. "Effects of ohmic heating on extraction of food-grade phytochemicals from colored potato". LWT 74 (2016): 493-503. http://dx.doi.org/10.1016/j.lwt.2016.07.074.
    Published • 10.1016/j.lwt.2016.07.074
  26. Oliveira, Hélder; Wu, Nao; Zhang, Qian; Wang, Jingyi; Oliveira, Joana; de Freitas, Victor; Mateus, Nuno; He, Jingren; Fernandes, Iva. "Bioavailability studies and anticancer properties of malvidin based anthocyanins, pyranoanthocyanins and non-oxonium derivatives". Food & Function 7 5 (2016): 2462-2468. http://dx.doi.org/10.1039/c6fo00445h.
    Published • 10.1039/c6fo00445h
  27. Oliveira, Hélder; Fernandes, Iva; Brás, Natércia F.; Faria, Ana; De Freitas, Victor; Calhau, Conceição; Mateus, Nuno. "Experimental and Theoretical Data on the Mechanism by Which Red Wine Anthocyanins Are Transported through a Human MKN-28 Gastric Cell Model". Journal of Agricultural and Food Chemistry 63 35 (2015): 7685-7692. http://dx.doi.org/10.1021/acs.jafc.5b00412.
    Published • 10.1021/acs.jafc.5b00412
  28. Oliveira, Hélder; Fernandes, Iva; de Freitas, Victor; Mateus, Nuno. "Ageing impact on the antioxidant and antiproliferative properties of Port wines". Food Research International 67 (2015): 199-205. http://dx.doi.org/10.1016/j.foodres.2014.10.034.
    Published • 10.1016/j.foodres.2014.10.034
Thesis / Dissertation
  1. Oliveira, Hélder. "The Biochemistry behind anthocyanins bioavailability". PhD, Universidade do Porto Faculdade de Ciências, 2018.
  2. Faculdade de Ciências. "Biodisponibilidade de antocianinas do vinho de mesa". Master, 2014. http://hdl.handle.net/10216/81444.

Intellectual property

Patent
  1. Fernandes, Iva; Joana Oliveira; Nuno Mateus; Victor de Freitas; Oliveira, Hélder; Paula Araújo; Patrícia Correia; Ana Rita Pereira. 2021. "Process for extraction and heme-synthesis of pyranoanthocyanins and skincare cosmetics formulations containing them". Portugal.
    Granted/Issued
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/11/13 Preparation, characterisation and stability evaluation of self-assembled anthocyanins-loaded zein/polysaccharide nanoparticles XXVI Encontro Galego Portugués de Química
University of Vigo (Vigo, Spain)
2024/09/19 Nanoencapsulation of anthocyanins from Red Cabbage (Brassica oleracea L. var. Capitata f. rubra) through zein and different anionic polysaccharides self-assembling 11th International Workshop on Anthocyanins
University of Leeds (Leeds, United Kingdom)
2024/09/18 Chemical characterisation, bioaccessibility and absorption of acylated anthocyanins from Edible Flowers 11th International Workshop on Anthocyanins
University of Leeds (Leeds, United Kingdom)
2023/11/16 Chromatography as a multidisciplinary tool: from chemical characterisation to molecular biology Plenary in the Department of Pharmaceutical Sciences
Università Del Piemonte Orientale (Novara, Italy)
2023/05/11 Edible Flowers Rich in Anthocyanins: Stability and bioaccessibility of an emerging, healthier and sustainable diet IJUP- Encontro de Investigação Jovem
Universidade do Porto (Porto, Portugal)
2023/04/19 Dietary polyglycosylated anthocyanins: The smart option? From potatoes to wine... 13th International Symposium on Viticulture and Enology
Northwest A&F University (Xuzhou, China)
2022/11/17 Dietary polyglycosylated anthocyanins, the smart option? XXVI Encontro Galego Portugués de Química
Universidade De Santiago de Compostela (Santiago de Compostela, Spain)
2022/09/06 On the Polyglycosylated Anthocyanins universe. International Academic Conference on Food Nutrition and Health 2022
Huazhong Agricultural University (Huazhong, China)
2022/06/22 Dietary polyglycosylated anthocyanins, the smart option? Towards their stability and bioavailability 3rd International Conference on Food Bioactives & Health
University of Parma (Parma, Italy)
2021/06/05 Wine-inspired blue compounds for Skin Photodynamic Therapy EUGLOH Summer School University of Porto
European University Alliance for Global Health (Porto, Portugal)
2020/11/05 Fucus vesiculosus phlorotannins as potential anti-inflammatory and antitumor agents Iberphenol- International Conference
University of Coimbra (Coimbra, Portugal)
2020/02/14 Technological approach for application of anthocyanins in the cosmetic industry IJUP- Encontro de Investigação Jovem
Universidade do Porto (Porto, Portugal)
2019/09/11 Recent Advances on the bioavailability of anthocyanins: a molecular approach 10th Workshop on Anthocyanins
Fondazione Edmund Mach (San Michelle all'Adige, Italy)
2018/11/23 Physical and Chemical characterization of anthocyanins from Purple-Fleshed Sweet Potato XXIVth Encontro Luso-Galego de Química
(Porto, Portugal)
2018/09/28 Nanobased targeted approach to study anthocyanins transport through stomach cells 2nd Conference on Food Bioactives and Health
(Lisboa, Portugal)
2018/07/19 Unveiling the molecular mechanism of acylated anthocyanins gastrointestinal absorption International Conference on Polyphenols 2018
(Madison, United States)
2017/11/16 Complex acylated Anthocyanins from Purple Sweet Potato towards novel technological applications XXIIIth Encontro Galego-Portugués de Química
(Ferrol, Spain)
2017/10/02 The biochemistry behind food polyphenols bioavailability and bioactivity IIth International Meeting of Medical Biochemistry and Biophysics Students
(Coimbra, Portugal)
2016/07/14 Study of the gastric absorption of anthocyanins. XXVIIIth International Conference on Polyphenols
(Vienna, Austria)
2015/10/26 Multiple-approach studies to assess anthocyanin gastric absorption – potential role of GLUT1. 7th International Conference on Polyphenols and Health
(Tour, France)
2015/03/27 On the gastric bioavailability of Red Wine anthocyanins IX iMM/CAML phD Student Meeting
Instituto de Medicina Molecular (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/11/01 - Current Anthocyanin-rich Edible Flowers as a sustainable and healthy food source: from their bioavailability to product development
Supervisor of Margarida Maria da Silva Teixeira
 Doctoral Programme in Sustainable Chemistry (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
2024/01/10 - Current Bioactivity of Edible Flowers Rich in Anthocyanins
Supervisor of Joana Catarina Silva Viegas
 Biotecnologia Medicinal (Degree)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023/09/01 - Current Sensorial study of vinegars and oils enriched with edible flowers rich in anthocyanins.
Supervisor of Mariana Presa
 Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2022/10/11 - Current From the bioavailability to bioactivity, and utilization of bioactive compounds from fruits and vegetables by-products.
Supervisor of Wen Tao
 Química Sustentável (PhD)
Universidade do Porto Faculdade de Ciências, Portugal

Wuhan Polytechnic University, China

REQUIMTE LAQV Porto, Portugal
2024/03/01 - 2024/12/06 Identification of anthocyanins from Vitis vinifera var. rubra leaves from different geographical locations in Italy
Co-supervisor of Marta Ganora
Università degli Studi del Piemonte Orientale Amedeo Avogadro, Italy
2022/09/20 - 2023/11/06 Flores Comestíveis Ricas em Antocianinas: A Bioquímica e Biotecnologia Rumo a uma Dieta Emergente, Mais Saudável e Sustentável
Supervisor of Margarida Maria da Silva Teixeira
 Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal

REQUIMTE LAQV Porto, Portugal
2023/03/14 - 2023/09/21 Extraction and Purification of Anthocyanins from Different Food Sources
Supervisor of Lorenzo De Luca
 Biotecnologie mediche, veterinarie e farmaceutiche (Master)
Università degli Studi del Piemonte Orientale Amedeo Avogadro Dipartimento di Scienze del Farmaco, Italy

Universidade do Porto Faculdade de Ciências, Portugal

REQUIMTE LAQV Porto, Portugal
2023/07/15 - 2023/07/31 Extração de compostos bioativos de flores comestíveis
Supervisor of Afonso Ribeiro
Universidade do Porto Faculdade de Ciências, Portugal
2023/07/15 - 2023/07/31 Extração de compostos bioativos de flores comestíveis
Supervisor of Débora Franqueira
Universidade do Porto Faculdade de Ciências, Portugal
2021/10/20 - 2022/07/23 Flores Comestíveis Ricas em Antocianinas: Rumo a uma dieta emergente, mais saudável e sustentável.
Supervisor of Inês Batista Ornelas de Moura Pina
 Química (Degree)
Universidade do Porto Faculdade de Ciências, Portugal

REQUIMTE LAQV Porto, Portugal
2021/10/05 - 2022/07/09 Flores comestíveis ricas em antocianinas Estudo exploratório das suas propriedades biológicas e biodisponibilidade in vitro
Supervisor of Maria Carlos Louro Santos
 Bioengenharia (Degree)
Universidade do Porto Faculdade de Engenharia, Portugal

REQUIMTE LAQV Porto, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/09/01 - Current PubhD Porto. way for PhD students to communicate their works in an informal way at a bar or cafe. (2024/09/01)
Round table (Member of the Organising Committee)
2019/06/03 - 2019/06/05 XXVI Encontro da Sociedade Portuguesa de Química (2019/06/03 - 2019/06/05)
Conference (Member of the Organising Committee)
 Universidade do Porto Faculdade de Ciências, Portugal
2018/04/02 - 2018/04/05 XI Encontro Nacional de Estudantes de Bioquímica (ENEBIOQ) (2018/04/02 - 2018/04/05)
Congress (President of the Organising Committee)
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/04/07 - 2017/04/10 X Encontro Nacional de Estudantes de Bioquímica (ENEBIOQ) (2017/04/07 - 2017/04/10)
Congress (President of the Organising Committee)
 Universidade do Minho, Portugal
2016/03/18 - 2016/03/21 IX Encontro Nacional de Estudantes de Bioquímica (ENEBIOQ) (2016/03/18 - 2016/03/21)
Congress (President of the Organising Committee)
 Universidade de Coimbra, Portugal
2015/03/27 - 2015/03/30 VIII Encontro Nacional de Estudantes de Bioquímica (ENEBIOQ) (2015/03/27 - 2015/03/30)
Congress (President of the Organising Committee)
 Universidade do Algarve, Portugal
2014/04/11 - 2014/04/14 VII Encontro Nacional de Estudantes de Bioquímica (ENEBIOQ) (2014/04/11 - 2014/04/14)
Congress (Member of the Organising Committee)
 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/09/09 - 2013/09/11 7th International Workshop on Anthocyanins 2013 (2013/09/09 - 2013/09/11)
Conference (Member of the Organising Committee)
 Universidade do Porto Faculdade de Ciências, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2020/07/15 Estudos de interação molecular entre os polifenóis e as proteínas do amendoim: efeitos na estrutura da proteína
(Thesis) Main arguer
 Catarina Ramos Dias (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2019/06/25 Exploração de complexos metal - antocianina/piranoantocianina com potencial aplicação na Terapia Fotodinâmica Tópica
(Thesis) Main arguer
 Inês Marisol Monteiro Rocha (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020/09/15 - Current Neurobioquímica Audiologia (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2020/02/06 - Current Bioquímica Farmácia (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2018/09/15 - Current Medicina Regenerativa e Terapia Celular Biotecnologia Medicinal (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2021/06/29 - 2021/07/02 Summer School in Nutrition and Food Sciences-The role of the academy to promote health Innovations in the Food System: new horizons for healthcare through technological applications with Food matrices and by-products. (Bachelor)
2019/02/06 - 2021 Química dos Alimentos e Nutrição Bioquímica (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal
2019/09/15 - 2020/02/20 Bioquímica Funcional Osteopatia (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019/11/18 - 2020/02/01 Monitorização Ambiental e Tecnologia Saúde Ambiental (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019/02 - 2019/07 Química Biológica II Biotecnologia Medicinal (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2020 - Current International Journal of Molecular Sciences (1422-0067) MDPI
2020 - Current Food Chemistry (0308-8146) Elsevier
Distinctions

Award

2023 Best Oral Communication
Investigação Jovem Universidade do Porto, Portugal
2022 3rd place at the Beyond the Lab BootCamp
Chaperone, Portugal
2022 AnthoE.Flos project - financed - best classification of the panel
Fundação para a Ciência e a Tecnologia, Portugal
2021 Theoretical and practical guide of the Proposal Writing of Horizon Europe projects
European Funding Management Consulting, Estonia
2021 Concurso Estímulo ao Emprego Científico - financed - best classification of the panel
Fundação para a Ciência e a Tecnologia, Portugal
2020 Best Poster Communication
Iberphenol - International Congress, Spain
2020 Best Oral Communication
Investigação Jovem Universidade do Porto, Portugal
2019 Best Poster Communication
International Conference on Polyphenols and Health, Japan
2019 Best Project
Fundo de capital de risco MustardSeedMaze, Portugal
2019 Research Grant by the WINPUT project (PTDC/QUI-OUT/29013/2017)
REQUIMTE LAQV Porto, Portugal
2018 Travel Grant for the International Conference on Polyphenols, USA
Groupe Polyphenols, France
2017 DQB Got Talent- Best Project
Universidade do Porto Faculdade de Ciências, Portugal
2016 Travel Grant for the International Conference on Polyphenols, Austria
Groupe Polyphenols, France
2015 PhD Grant (PD/BD/106062/2015)
Fundação para a Ciência e a Tecnologia, Portugal