Identification
Personal identification
- Full name
- Ricardo Fernando Santos Amorim
Citation names
- Amorim, Ricardo
Author identifiers
- Ciência ID
- B11D-8714-A7C5
- ORCID iD
- 0000-0002-5177-049X
- Scopus Author Id
- 57195236911
Email addresses
- ricardo.amorim@i3s.up.pt (Professional)
Telephones
- Mobile phone
-
- 916960211 (Personal)
Addresses
- R. Alfredo Allen 208, 4200-135, Paranhos , Porto , Portugal (Professional)
- Rua Camões Nº31, Costa - Mansores, 4540-416, Arouca, Arouca, Portugal (Personal)
Knowledge fields
- Natural sciences - Biological Sciences - Biochemistry
- Natural sciences - Biological Sciences - Cell Biology
- Natural sciences - Biological Sciences - Molecular Biology
- Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
- Medical and Health Sciences - Basic Medicine - Toxicology
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Proficiency (C2) | Upper intermediate (B2) | Advanced (C1) | |
Spanish; Castilian | Elementary (A2) | Elementary (A2) | Elementary (A2) | Elementary (A2) |
Education
Degree | Classification | |
---|---|---|
2017/11 - 2022/04/21
Concluded
|
Experimental Biology and Biomedicine (BEB) (Doctor)
Major in Molecular, Cellular and Developmental Biology
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
|
|
2019/01/07 - 2019/01/18
Concluded
|
II Modular Training in Laboratory Animal Science - Advanced course (Especialização pós-licenciatura)
Universidade de Coimbra, Portugal
|
|
2011 - 2013
Concluded
|
Biochemistry (Master)
Major in Sem especialização
Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal ""Development of mitochondria-targeted antioxidants:
innovative therapeutic strategy for neurodegenerative diseases"" (THESIS/DISSERTATION)
|
17/20 |
2008 - 2011
Concluded
|
Biochemistry (Bachelor)
Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal ""Stimulated gastrointestinal digestion of Port wines. Effect on human colon cancer cell lines proliferation"" (THESIS/DISSERTATION)
|
14/20 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2023/07/01 - Current | Researcher (Research) | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
2022/06/01 - 2023/05/31 | Postdoc (Research) | Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal |
2019/09 - 2019/12 | Visiting Researcher (Research) | CLADE GmbH , Germany |
Others
Category Host institution |
Employer | |
---|---|---|
2017/11/01 - 2022/04/21 | pHD candidate | Fundação para a Ciência e a Tecnologia, Portugal |
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal | ||
2017/07 - 2017/10 | Research Fellow (BI) Fellowship - Integration of research project "MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidants Delivery to Mitochondria" | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2017/01 - 2017/06 | Research Fellow (BI) Fellowship - Integration of research project "MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidants Delivery to Mitochondria" | Universidade do Porto Faculdade de Ciências, Portugal |
2014/04 - 2015/05 | Research Fellow (BI) Fellowship - Integration of research and development project entitle "Identifying the source of an odor complaint using a portable electronic nose" | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
2014 - 2015 | R&D associate | M.A.SILVA - CORTIÇAS, S.A., Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2023/03 - 2025/03 | MitoTARGET4AD: Improving Nature for a Novel Disruptive Treatment for Alzheimer's Disease
2022.15117.CBM
Researcher
|
Ongoing
|
Contract
Designation | Funders | |
---|---|---|
2023/07/01 - Current | CANCER PREVENTION VS CANCER TREATMENT: THE RARE TUMOUR RISK SYNDROMES BATTLE
101095483
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
European Commission
Ongoing
|
2023 - Current | Remodelação metabólica e mitocondrial induzida pela atividade física em fibroblastos de pacientes com a Doença de Parkinson
2022.01232.PTDC
Other
|
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
|
2022/06 - Current | MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease
V2.0 IT137-22-151
Post-doc
|
Comissão de Coordenação e Desenvolvimento Regional do Centro (CCDRC) |
2021/01/01 - Current | BraveHEART: Improving Nature by Addressing Bioactiv Dietary Polyphenols to Mitochondria for the Protection of Cardiac Complications
in Non-Alcoholic Fatty Liver Disease
EXPL/BIA-BQM/1361/2021
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Associação para a Inovação e Desenvolvimento da FCT |
2021 - Current | Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral
Sclerosis
PTDC/BTM-ORG/0055/2021
Other
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
|
2019/06/01 - Current | CôaMedPlants: Preservation of natural and cultural heritage and scientific validation of practices with medicinal plants from
Côa Valley
COA/BRB/0019/2019
Post-doc Fellow
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
|
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
|
2017/06/01 - 2022/08/31 | mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease
734719
Invited Scientist Fellow
|
European Commission
Concluded
|
2018/07/26 - 2021/07/25 | Uso de fitoquímicos redox-activos para desencadear a hormesis mitocondrial: Desenvolvimento de uma nova geração de ingredientes
para a cosmética
PTDC/BIA-MOL/28607/2017
Universidade do Porto, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2018/07/26 - 2021 | SkinSHIELD - Redox-active phytochemicals triggering mitochondrial hormesis: developing a new generation of cosmetic active
ingredients
POCI-01-0145-FEDER-028607
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Associação para a Inovação e Desenvolvimento da FCT
Concluded
|
2019/01/01 - 2019/12/31 | CNC. IBILI
UID/NEU/04539/2019
Integration into Research Grant Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra, Portugal Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2019/01/01 - 2019/12/31 | Centro de Investigação em Química da Universidade do Porto (Chemistry Research Center of the University of Porto)
UID/QUI/00081/2019
Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Centro de Investigação em Química, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2017/01/01 - 2017/10/31 | MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria
Pathophysiology
PTDC/DTP-FTO/2433/2014
Research Fellow
|
Associação para a Inovação e Desenvolvimento da FCT
Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference poster |
|
Journal article |
|
Thesis / Dissertation |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/06/05 | Unlocking Therapeutic Potential: Equisetum ramosissimum Extracts from Portugal's Côa Valley Mitigate Metabolic Liver Disease | 58th ESCI Annual Scientific Meeting (ASM)
(Barcelona, Spain)
|
2023/11 | AntiOxCIN6 potentiates cisplatin anticancer therapy by lowering mitochondrial metabolism while upregulating energetic glycolytic dependence | Mitochondria in Aging, Cancer and Cell Death - MAC 2023
MAC organization (Coimbra, Portugal)
|
2023/03/26 | O antioxidante mitocondriotrópico AntiOxCIN4 melhora a função mitocondrial e previne o bloqueio autofágico associado à esteatose hepática em ratinhos alimentados com dieta obesogénica. | 19º Congresso Portugês de Diabetes
Sociedade Portuguesa Diabetes (Vilamoura, Portugal)
|
2023/02/01 | The mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 lowers mitochondrial metabolism while upregulating glycolysis in human HepG2 cells | Sociedade Portuguesa de Farmacologia (SPF) Meeting at University of Coimbra
Sociedade Portuguesa de Farmacologia (SPF) (Coimbra, Portugal)
|
2023/01/12 | Mitochondriotropic antioxidant AntiOxCIN4 improves mitochondrial function and prevents Non-Alcoholic Fatty Liver (NAFL)-associated autophagic blockage in Western diet (WD)-fed mice | III MAD Meeting
CIBB (Coimbra, Portugal)
|
2022/06/08 | Mitochondriotropic Antioxidants Based on Hydroxycinnamic Acids Activates Nrf2-Mediated Cell Signalling Responses to Oxidative Stress: Implications in Non-Alcoholic Fatty Liver Disease (NAFLD) | 56th Annual meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Bari, Italy)
|
2022/01/19 | Mitochondria-targeted antioxidant AntiOxCIN4 improved liver steatosis in Western Diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation and quality control mechanism | BEB day
(Coimbra, Portugal)
|
2021/06/10 | Decrypting the Nrf2-dependent antioxidant mechanism of action behind the beneficial effects of the mitochondriotropic cinnamic acid AntiOxCIN4 | 55th ESCI Annual Scientific Meeting |
2020/03/05 | Mitochondriotropic Cinnamic Acid Antioxidant Improves Cellular Resistance to Stress | MuTaLig COST ACTION CA15135 WG meeting 2020
MuTaLig COST ACTION (Izmir, Turkey)
|
2019/10/27 | Antioxidant hormetic-like properties of AntiOxCIN4, a novel hydroxycinnamic acid-based mitochondria-targeted agent | 10th World Congress on Targeting Mitochondria
(Berlin, Germany)
|
2019/06/15 | Design and development of multi-target agents for neurodegenerative diseases. | Meeting of the Paul Ehrlich Euro-PhD Network - MuTaLig COST action
(Catanzaro, Italy)
|
2019/06/13 | PEGylation technology – the second chance for non-bioavailable drug candidates | Meeting of the Paul Ehrlich Euro-PhD Network - MuTaLig COST action
(Catanzaro, Italy)
|
2019/05/23 | Unraveling the mechanism throughout mitochondriotropic cinnamic acid antioxidants increase cellular stress responses in HepG2 cells | 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
(Coimbra, Portugal)
|
2019/02/20 | Improving the activity of dietary cinnamic and benzoic acids for the treatment of neurodegenerative disorders | 26th Young research fellows meeting
(Paris, France)
|
2019/02/06 | Targeting Phenolic Dietary Antioxidants to Mitochondria to Modulate Redox Signaling and Metabolism | Sociedade Portuguesa de Farmacologia (SPF) Meeting
(Porto, Portugal)
|
2018/10/25 | Mitochondria-targeted antioxidants in human hepatic cells: a conceivable therapy for non-alcoholic fatty liver disease | 9th World Congress on Targeting Mitochondria
(Berlin, Germany)
|
2018/10/18 | Effects of mitochondria-targeted antioxidants in human hepatic cells: a possible therapy for hepatic steatosis? | 3nd WG meeting – MuTaLig COST Action
(Valletta, Malta)
|
2018/10/18 | History in the making: development of multi-target-directed ligands for Alzheimer's disease that modulate oxidative stress/mitochondria quality and the cholinergic system | 3rd Annual Meeting of COST Action CA15135
(Valletta, Malta)
|
2018/05/30 | Mitochondriotropic cinnamic acid antioxidants increase cellular stress responses in HepG2 cells: Involvement of mitochondrial ROS signaling in a possible therapy for hepatic steatosis? | 52nd European Society for Clinical Investigation
(Barcelona, Spain)
|
2018/03/15 | Mitochondriotropic cinnamic acid antioxidants increase cellular stress responses in HepG2 cells | 2nd WG meeting – MuTaLig COST Action.
(Tenerife, Spain)
|
2018/03/15 | Development of multi-target agents based on hydroxybenzoic acid scaffold endowed with mitochondriotropic antioxidant and cholinesterase inhibitory activity | MuTaLig COST action
(Tenerife)
|
2017/05/26 | Effects of different targeting cations on the toxicity profile of mitochondriotropic-hydroxycinnamic antioxidants | In MitoPorto: Advances in Mitochondrial Research International Symposium |
2017/05/19 | MitoK3, a novel mitochondriotropic menadione derivative with cytotoxic effects on cancer cells | 51th Annual Scientific Meeting of the European Society for Clinical Investigation
ESCI (Genoa, Italy)
|
2015/07/03 | Targeting dietary hydroxybenzoic acids to mitochondria: A refined strategy to improve Nature | V Meeting of the Paul Ehrlich MedChem Euro-PhD Network
(Krakow, Poland)
|
2013/09/27 | Makeup of natural antioxidants: Design and development of smart carriers to deliver dietary phenolic acids to mitochondria | 3rd Meeting of the Paul Ehrlich MedChem Euro- PhD Network
(Cagliari)
|
2013/09/04 | Remaking of Dietary Antioxidants: Targeting MitoBEN's to Mitochondria as a New Therapeutic Strategy | 10º Portuguese National Meeting of Organic Chemistry
Sociedade Portuguesa de Química (Lisboa, Portugal)
|
2013/02/15 | Development of Smart Carriers For Delivering Menadione to Mitochondria | 6º Meeting of young researchers of University of Porto
(Porto, Portugal)
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2023/12 - 2023/12 | Participation in the Congress Organizing Committee "Mitochondria in Aging, Cancer and Cell Death" - MAC2023 (2023 - 2023)
Congress (Member of the Organising Committee)
|
|
2019/05/22 - 2019/05/24 | Participation in the Congress Organizing Committee of 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (22 to 24th May, 2019, Coimbra, Portugal). (2019/05) |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2017 - Current | Noite Europeia dos Investigadores activities at the Center for Neuroscience and Cell Biology
Workshop
|
Noite Europeia dos Investigadores
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
2019/07/08 - 2019/07/11 | 12th MiP/MitoEAGLE Training School 2019
Symposium
|
Mitochondrial respiratory physiology: Challenges on data sharing, reproducibility, and interpretation
Universidade de Coimbra, Portugal
|
2018/07/13 - 2018/07/13 | MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium
Symposium
|
MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium
Universidade do Porto Faculdade de Farmácia, Portugal
|
2017/05/26 - 2017/05/26 | MitoPorto: Advances in Mitochondrial Research International Symposium
Symposium
|
In MitoPorto: Advances in Mitochondrial Research International Symposium
Universidade do Porto Faculdade de Farmácia, Portugal
|
Ad Hoc journal article review
Journal title (ISSN) | Publisher | |
---|---|---|
2023/10 - Current | Nutrients (2072-6643) | MDPI |
2023/07 - Current | Journal of bioenergetics and biomembranes (15736881, 0145479X) | Spinger |
2021/06/01 - Current | European Journal of Clinical Investigation (0014-2972) | Wiley |
Association member
Society Organization name | Role | |
---|---|---|
2024/06 - Current | European Association for Cancer Research | |
2022 - Current | Portuguese Society of Diabetes | |
2021 - Current | European Association for the Study of the Liver | |
2018 - Current | European Society for Clinical Investigation |
Committee member
Activity description Role |
Institution / Organization | |
---|---|---|
2024/06/13 - 2024/06/15 | Committee Member of the 5th International Gastric Cancer Linkage Consortium (IGCLC) meeting 2024,
Porto, Portugal. (2024/06) (2024/06/13 -2024/06/15)
Member
|
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2017 - Current | Several Bachelor students | |
2019 - 2019 | Visiting Students | Vincenzo Piedimonte (Bachelor student) (2019), University of Sannio, Italy.. |
2018 - 2018 | Visiting Students | Theresa Thiel (Laboratory Technician) (2018), Mediagnostic, German |
Distinctions
Award
2024 | Best poster presentation at 20th Portuguese Diabetes Congress
Sociedade Portuguesa de Diabetologia, Portugal
|
2024 | Tavel grant from Annual Meeting of the ESCI (2023)
European Society for Clinical Investigation, Netherlands
|
2023 | Tavel grant from Annual Meeting of the ESCI (2023), Prague, Czech Republic |
2022 | Best poster presentation at 56th Annual Meeting of the ESCI (2022), Bari, Italy
European Society for Clinical Investigation, Netherlands
|
2020 | 2ª Best Oral Presentation - Action CA15135. Izmir, Turkey (2020). |
2020 | ITC Conference Grant - Action CA15135. Izmir, Turkey (2020).
European Cooperation in Science and Technology, Belgium
|
2018 | ITC Conference Grant - Action CA15135. Valletta, Malta (2018).
European Cooperation in Science and Technology, Belgium
|
2018 | Student travel grant - ESCI 2018 - European Society for Clinical Investigation, Barcelona, Spain.
European Society for Clinical Investigation, Netherlands
|
2018 | ITC Conference Grant - Action CA15135. La Laguna, Tenerife (2018) |
2018 | Poster Award at the 52nd Annual Meeting of the European Society for Clinical Investigation (2018), Barcelona, Spain. |
2017 | Doctoral scholarship - Foundation for Science and Technology (FCT), Lisbon, Portugal - SFRH/BD/131070/2017
Associação para a Inovação e Desenvolvimento da FCT, Portugal
|
2017 | Research Fellow (BI) Fellowship - Center for Neurosciences and Cell Biology (CNC), Coimbra, Portugal PTDC-DTP-FTO-2433-2014 |
2016 | Research Fellow (BI) Fellowship - Faculty of Sciences (FCUP), Porto, Portugal PTDC-DTP-FTO-2433-2014 |
2015 | Poster Award at the 49th Annual Meeting of the European Society for Clinical Investigation (2015), Cluj-Napoca, Romania. |