Identification
Personal identification
- Full name
- Pedro Lopes Granja
Citation names
- Granja, Pedro L.
- Pedro L. Granja
- Granja, P.
- Pedro Granja
Author identifiers
- Ciência ID
- DB1F-B9B7-E4FD
- ORCID iD
- 0000-0003-2761-4929
- Google Scholar ID
- iBd2bxgAAAAJ
- Researcher Id
- B-1685-2008
- Scopus Author Id
- 6602391346
Websites
- http://www.pedrogranja.net (Professional)
- http://www.biomat.net (Feed)
- http://www.i3s.up.pt (Professional)
Knowledge fields
- Medical and Health Sciences - Medical Biotechnology - Biomaterials
- Engineering and Technology - Industrial Biotechnology - Bioproducts Biomaterials
- Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
- Engineering and Technology - Materials Engineering - Materials Engineering
- Engineering and Technology - Nano-technology - Nano-materials
- Engineering and Technology - Medical Engineering - Medical Engineering
- Medical and Health Sciences - Medical Biotechnology - Biomaterials
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Advanced (C1) | Proficiency (C2) | Advanced (C1) | Advanced (C1) | Proficiency (C2) |
French | Upper intermediate (B2) | Advanced (C1) | Elementary (A2) | Advanced (C1) | Upper intermediate (B2) |
Spanish; Castilian | Beginner (A1) | Intermediate (B1) | Beginner (A1) | Beginner (A1) | |
Italian | Beginner (A1) | Intermediate (B1) | Beginner (A1) | Beginner (A1) |
Education
Degree | Classification | |
---|---|---|
2001
Concluded
|
PhD in Engineering Sciences (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
"Biomimetic Natural Materials for Bone Regeneration" (THESIS/DISSERTATION)
|
Approved |
1993
Concluded
|
Engenharia Metalúrgica (Licenciatura)
Universidade do Porto Faculdade de Engenharia, Portugal
"Bioreactive Polymer/Ceramic Composites" (THESIS/DISSERTATION)
|
14 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2018 - Current | Principal Investigator (Research) | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
i3S - Instituto de Investigação e Inovação em Saúde, Portugal | ||
2013 - 2018 | Principal Investigator (Research) | Instituto Nacional de Engenharia Biomédica, Portugal |
2001 - 2013 | Researcher (Research) | Instituto Nacional de Engenharia Biomédica, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2016/04/01 - 2017 | Associate Professor (University Teacher) | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2016 - 2017 | Invited Associate Professor (University Teacher) | Universidade do Porto Faculdade de Engenharia, Portugal |
2013 - 2017 | Assistant Professor (University Teacher) | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2013 - 2017 | Visiting Professor (University Teacher) | Universidade de Aveiro, Portugal |
2005/01/01 - 2010 | Invited Assistant (University Teacher) | Universidade do Porto Faculdade de Engenharia, Portugal |
Universidade do Porto Faculdade de Engenharia, Portugal |
Positions / Appointments
Category Host institution |
Employer | |
---|---|---|
1998 - Current | Editor-in-Chief and Founder | Biomat.net, Portugal |
i3S - Instituto de Investigação e Inovação em Saúde, Portugal | ||
2014/01/01 - 2017 | Board Member | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
2013/05/31 - 2017 | Board member | Sociedade Portuguesa de Materiais, Portugal |
2012/10/01 - 2017 | Manager of Laboratory, Institute, Museum, Centre or Observatory | Instituto Nacional de Engenharia Biomédica, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2012/03/01 - 2014/12/31 | Coordinator of the NEWTherapies Group | Instituto Nacional de Engenharia Biomédica, Portugal |
2006/03/01 - 2012/03/01 | Deputy coordinator | Instituto Nacional de Engenharia Biomédica, Portugal |
2007 - 2007 | Invited Professor | Cité Internationale Universitaire de Paris, France |
2004/01 - 2004/07 | Visiting Assistant Research Scientist | University of Michigan, United States |
1998 - 2001 | PhD student | INSERM, France |
1994 - 2001 | PhD student | Instituto Nacional de Engenharia Biomédica, Portugal |
1992 - 1994 | Teaching Assistant in laboratory courses | Universidade do Porto Faculdade de Engenharia, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2013 - 2015 | Industrial biological biomaterials doctorate (IB2)
IB2
Supervisor
INEB - Instituto de Engenharia Biomédica, Portugal
|
European Commission
Concluded
|
2012 - 2013 | Role of CD44 as a new mechanoreceptor
ref
Principal investigator
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação Calouste Gulbenkian
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2023/01/01 - Current | Uncovering biomechanical drivers in skin fibrosis to engineer a novel biomimetic 3D tissue model (3DFibroSkin)
2022.06048.PTDC
Researcher
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
|
2023/01/09 - 2026/01/09 | Instituto de biofabricación en red para el envejecimento saludable (IBEROS+)
0072_IBEROS_MAIS_1_E
Principal investigator
|
Ongoing
|
2015 - 2018 | In situ skin tissue engineering (SKINPRINT)
PTDC/BBB-ECT/2145/2014
Principal investigator
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2015 - 2018 | SKINCHIP
SKINCHIP
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2016 - 2017 | Northern discoveries: The Discoveries CTR - Setting Sails. The Discoveries Centre for Regenerative and Precision Medicine
Northern discoveries
Researcher
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
NORTE2020 - North Region Operational Program
Concluded
|
2015 - 2017 | Bioengineered therapies for infectious diseases and tissue regeneration (BIOTHERAPIES)
NORTE2020
Principal investigator
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
NORTE2020 - North Region Operational Program
Concluded
|
2015 - 2017 | Bioengineering of soft tissues through placental extracellular matrices and stem cells of varied origins
placental MSC
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
|
2016/04 - 2016/11 | Unraveling the combined influence of hypergravity, topography and biochemical cues on tendon cell behavior (ACHILES)
achiles
INEB - Instituto de Engenharia Biomédica, Portugal
|
European Space Agency (ESA)
Concluded
|
2013 - 2016 | Neuro-enhancement responsible research and innovation (NERRI)
NERRI
Researcher
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
European Commission
Concluded
|
2013 - 2015 | Integrated program on biomedical engineering for regenerative therapies and cancer (Deputy Coordinator)
North Region Operational Program ON.2
INEB - Instituto de Engenharia Biomédica, Portugal
|
North Region Operational Program ON.2
Concluded
|
2013 - 2015 | Development and biological evaluation of tissue engineered injectable systems
Hungarian-Portuguese Intergovernmental S&T Cooperation Programme
Principal investigator
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2012 - 2015 | Tumor-targeted nanoparticles for early diagnosis of gastric cancer (TUMORTAG)
PTDC/CTM-NAN/120958/2010
Principal investigator
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2014/04 - 2014/09 | Influence of hypergravity on the formation of blood vessels by endothelial cells (ANGIOGRAVITY)
Angiogravity
Principal investigator
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
European Space Agency (ESA)
Concluded
|
2012 - 2014 | Development of a biomaterial microarray for high-throughput screening of 3D cell cultures
3D cell cultures
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia |
2011 - 2014 | New materials for drug/gene delivery based on the self-assembly of dendrimer-chitosan-single stranded DNA (DENDRIMAT)
DENDRIMAT
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2010 - 2013 | Sr-Releasing injectable system for vertebroplasty (srHYBRID)
srHYBRID
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2010 - 2013 | Extracellular matrix-like multifunctional biomaterials for bone regeneration (BIOMATRIX)
BIOMATRIX
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2008 - 2012 | Novel biofunctional highly porous polymer scaffolds and techniques controlling angiogenesis for the regeneration and repair
of the degenerated intervertebral disc (DISC REGENERATION)
DISC REGENERATION
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
European Commission
Concluded
|
2007 - 2010 | Targeting nanoprobes for early detection of invasive cancer cells using hereditary diffuse gastric cancer as a model (NANOPROBE)
NANOPROBE
Principal investigator
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2007 - 2010 | Design of new gene delivery vectors based on dendrimers, alginate and the RGD sequence for bone tissue engineering (DENDRALGENE)
DENDRALGENE
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2007 - 2009 | Bridging biomaterial research excellence between industry and academia across Europe (BRIDGE)
BRIDGE
Instituto Nacional de Engenharia Biomédica, Portugal
|
European Commission
Concluded
|
2005 - 2008 | Bone regeneration by stimulation of angiogenesis (ANGIO)
ANGIO
Principal investigator
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2004 - 2006 | Core Laboratories for the Improvement of medical devices in clinical practice from the failure of the explanted prostheses
analysis (FEPA)
FEPA
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
European Commission
Concluded
|
2003/05/02 - 2006 | An injectable enzyme delivery system based on apatite nanoparticles and natural hydrogel microspheres for bone regeneration
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2004/01 - 2004/12 | Microencapsulation systems for cotransplantation
ref
Principal investigator
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação Luso-Americana
Concluded
|
2001 - 2002 | Novel intervertebral disc prostheses (DISC) (Deputy Coordinator of INEB’s team)
DISC
Post-doc Fellow
INEB - Instituto de Engenharia Biomédica, Portugal
|
European Commission
Concluded
|
2001 - 2002 | Development of cellulosic biomaterials for bone regeneration
biomaterials for bone regeneration
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
1999 - 2001 | Bioactive biomaterials as supports for the immobilisation and subsquent in vivo release of imiglucerase: A new therapeutic
approach for the treatment of Gaucher Disease
Gaucher
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
1999 - 2001 | Tailoring of biomaterials at the nanoscale: Applications in bone surgery and heamotherapy
ref
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Bilateral Cooperation between Portugal (ICCTI) and R. P. China (Ministry of Science and Technology)
Concluded
|
1998 - 2000 | Medical devices for collecting, processing and storing blood and blood constituents (CARE)
CARE
Post-doc Fellow
INEB - Instituto de Engenharia Biomédica, Portugal
|
Ministério da Economia
Concluded
|
1997 - 2000 | Biomineralization of implant materials (BIOMINERAL)
BIOMINERAL
Researcher
INEB - Instituto de Engenharia Biomédica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
1995 - 1996 | Biomatériaux et suppléance fonctionelle
Biomatériaux
Researcher
INSERM, France
|
Association Génie Biologique et Médical (GBM) Aquitaine
Concluded
|
Outputs
Publications
Book |
|
Book chapter |
|
Conference abstract |
|
Conference paper |
|
Journal article |
|
Thesis / Dissertation |
|
Other
Other output |
|
Activities
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023 - Current | Gastric Patch – A Bioprinted 3D Engineered Patch for Gastric Ulcer Healing
Supervisor
|
PRODEB, FEUP (PhD)
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
2020 - Current | Implantable electrospun nanofibers containing gold nanoparticles for local enhancement of radiotherapy in gastric tumors
Supervisor
|
PhD Program in Bomedical Engineering (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2014 - Current | Cancer and Mechanobiology
Supervisor of Maria Manuela Brás
|
PhD Program in Bomedical Sciences (PhD)
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
2014 - Current | Mechanobiology of cancer cells using atomic force microscopy
Supervisor
|
PhD Program in Bomedical Engineering (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2023 - 2026 | Bioprinting of a vascularised cell-laden spinal cord graft: an anatomically relevant approach
Supervisor
|
PRODEB, FEUP (PhD)
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
|
2021 - 2021 | Development of wound dressings based on a pectin and chitosan interpenetrating polymer network
Supervisor
|
Mestrado em Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2014 - 2021 | A tissue engineering approach to fabricate a stomach-on-a-chip: A biomimetic device to decode the role of CD44V6 in cancer
cells
Supervisor
|
BiotecHealth (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2015 - 2020 | Seeking for new p53-activating agents: effective therapies for colorectal cancer
Co-supervisor
|
BiotechHealth - International Doctoral Program in Molecular and Cellular Biotechnology Applied to Health Sciences (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2016 - 2019 | Functionalized nanoparticles loaded into an injectable cryogel for combined chemotherapy and cancer vaccination
Co-supervisor
|
PhD Program in Bomedical Sciences (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2016 - 2019 | Colorectal cancer triple co-culture spheroid model to assess the biocompatibility and anticancer properties of polymeric nanoparticles
Co-supervisor
|
PhD Program in Bomedical Sciences (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2012 - 2019 | Bioengineering 3D models to deconstruct the role of extracellular matrix microenvironment in gastric cancer
Supervisor
|
PhD Program in Biomedical Engineering (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2015 - 2018 | Stomach Patch
Supervisor
|
MSc in Bioemdical Engineering (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2014 - 2018 | Fab-conjugated PLGA nanoparticles effectively target cancer cells expressing human CD44v6
Co-supervisor
|
BiotechHealth (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2012 - 2018 | Hydrogel bioinks for bioprinting of bioengineered 3D constructs for skin tissue engineering
Co-supervisor
|
PhD Program in Bomedical Sciences (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2012 - 2018 | Spheroids in vascularisation
Co-supervisor
|
Industrial Biological Biomaterials Doctorate (IB2). EID – European Industrial Doctorates, Marie Curie Initial Training Networks
(ITN) (PhD)
European Commission Seventh Framework Programme for Research and Technological Development Joint Technology Initiatives, Belgium
|
2012 - 2017 | Nanopharmaceuticals
Co-supervisor
|
PhD Program in Bomedical Sciences (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2012 - 2017 | Hybrid electrospun PCL/gelatine nanostructures for skin regeneration
Co-supervisor
|
PhD Program in Bomedical Sciences (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2011 - 2017 | Hybrid systems in tissue engineering
Supervisor
|
PhD Program in Biomedical Engineering (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2016 - 2016 | Cellulose nanofibril-cell adhesive peptide conjugates for 3D printed skin tissue model
Co-supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2016 - 2016 | Molecularly imprinted intelligent scaffolds for tissue engineering applications
Supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2016 - 2016 | The role of adsorbed proteins in the internalization of polymeric nanoparticles
Supervisor
|
MSc in Biochemistry (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2016 - 2016 | Methacrylated hyaluronic acid and pectin cell-laden hydrogels for skin emulation
Supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2015 - 2015 | Dynamically Adhesive Micropatterned Substrates for Studying and Controlling Cell Adhesion and Migration
Co-supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2015 - 2015 | Cell-laden micropatterns using self-assembled cell-ECM microtissues in soft pectin hydrogels
Supervisor
|
Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2014 - 2014 | Complex cell-based model of intestine permeability
Co-supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2014 - 2014 | Establishment of a cellularized artificial model of the gastric wall
Supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2008 - 2014 | Deconstruction CD44 - Engineering 3 D matrices to elucidate CD44 modulation in gastric malignancy
Supervisor
|
PhD Program in Biomedicine (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
|
2013 - 2013 | 3D Hybrid Scaffolds for Tissue Engineering
Supervisor
|
Engenharia Biomédica (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2013 - 2013 | Pectin hydrogels for dermal substitutes
Supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2007 - 2013 | Protease-sensitive hydrogels as 3D cellular microenvironments
Supervisor
|
PhD Program in Biomedical Engineering (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2008 - 2012 | Modulation of angiogenesis by fibroblasts in tissue regeneration
Supervisor
|
PhD Program in Biomedical Engineering (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2008 - 2012 | Matrix-driven formation of MSC-ECM microtissues on soft alginate hydrogels
Co-supervisor
|
International Iberian Nanotechnology Laboratory, Portugal
|
2008 - 2011 | Biofunctional chemically modified pectin for cell immobilization
Co-supervisor
|
Politecnico di Milano, Italy
|
2005 - 2011 | Exploring the crosstalk between mesenchymal stem cells and endothelial cells in bone tissue engineering
Supervisor
|
PhD Program in Biomedical Engineering (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
2002 - 2008 | Osteoprogenitors Differentiation Is Regulated by Cell-cell and Cell-extracellular Matrix Interactions: Implications for Bone
Tissue Regeneration
Supervisor
|
Ciências de Engenharia (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
|
Distinctions
Title
2020 | Fellow of Biomaterials Science and Engineering (FBSE) |
Other distinction
2016 | Fundamental Research Prize (Joana Crisóstomo) |
2016 | Best Poster in Fundamental Research Award (Joana Crisóstomo) |
2015 | Best Poster Award (Daniel Carvalho, Guilherme Aresta, Miguel Ferreira and Raquel Costa-Almeida) |
2015 | Best Student Oral Presentation in Life Sciences (Miguel Ferreira) |
2014 | Prize for best poster (Sara C. Neves). Co-author |
2014 | Spin Your Thesis! 2014 (Antigravity project) |
2014 | Best PhD Thesis in Doctoral Program in Biomedicine 2013-2014 (Cristiana Branco da Cunha) |
2013 | 2nd Prize on the Poster Competition (Raquel Costa-Almeida) |
2012 | Chair in Biomaterials, University of Havana, Cuba |
2011 | Prize for Best Poster (Cristina C. Barrias). Co-author |
2011 | YSF Excellence Award |
2011 | Prize for Best Poster (Ana Filipa Lourenço). Co-author |
2010 | Prize for Best Poster Award (F. Raquel Maia). Co-author |
2009 | Prize Best Poster of the Day (João L. Lopes); co-author |
2009 | Prize for Best Oral presentation (Susana Guerreiro); co-author |
2009 | Prize for Best Oral presentation (José Luís Santos); co-author |
2007 | Best oral presentation (M Grellier); co-author |
2006 | Jean Leray Award
European Society for Biomaterials (ESB), France
|
2003 | Special Oral presentation Award (Isabel F. Amaral); co-author |