Pedro Lopes Granja (DB1F-B9B7-E4FD)

Curriculum Vitae

Pedro L. Granja was born in 1970, in Porto, Portugal. His high school studies took place in Porto (Portugal) and São Paulo (Brazil). He graduated in Metallurgical Engineering at the Univ. Porto (UP) in 1993 and obtained his PhD in Engineering Sciences, also from UP in 2001, as a result of studies carried out at Instituto de Engenharia Biomédica (INEB, UP) and INSERM U.443 (Univ. Bordeaux, France). He carried out post-doctoral studies at INEB, was Invited Visiting Scientist at the Univ. Michigan (USA, 2004) and Invited Professor at the Univ. Paris 13 (France, 2009). He is presently Leader of the Biofabrication Group at Instituto de Investigação e Inovação em Saúde (i3S, UP). His research interests lie at the intersection between materials science, biology and medicine, namely on the development of biomaterials for biofabrication using principles and tools from tissue engineering and regenerative medicine. His research work has been focused on the molecular design of biofunctional hydrogels as 3D biomimics of the extracellular matrix. He received the 2006 Jean Leray Award by the European Society for Biomaterials (ESB) and is internationally reputed as founder (1998) and Editor-in-Chief of the Biomaterials Network (Biomat.net). He was recently distinguished as Fellow of Biomaterials Science and Engineering (FSBE, 2020). Moreover, he serves as expert for several national and international funding agencies, organizations and companies. So far, he has authored more than 125 articles in international indexed journals, 11 book chapters, 2 patents and presented 170 invited lectures worldwide. At present, he has an h-index of 52 and his publications have been cited over 8200 times (Google Scholar). Homepage: www.pedrogranja.net

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Identificação

Identificação pessoal

Nome completo: Pedro Lopes Granja

Nomes de citação

Granja, Pedro L.
Pedro L. Granja
Granja, P.
Pedro Granja

Identificadores de autor

Ciência ID: DB1F-B9B7-E4FD
ORCID iD: 0000-0003-2761-4929
Google Scholar ID: iBd2bxgAAAAJ
Researcher Id: B-1685-2008
Scopus Author Id: 6602391346

Websites

http://www.pedrogranja.net (Profissional)
http://www.biomat.net (Feed)
http://www.i3s.up.pt (Profissional)

Domínios de atuação

Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Bioprodutos Biomateriais
Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
Ciências da Engenharia e Tecnologias - Engenharia dos Materiais - Engenharia dos Materiais
Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanomateriais
Ciências da Engenharia e Tecnologias - Engenharia Médica - Engenharia Médica
Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C2)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C2)
Francês	Utilizador independente (B2)	Utilizador proficiente (C1)	Utilizador elementar (A2)	Utilizador proficiente (C1)	Utilizador independente (B2)
Espanhol; Castelhano	Utilizador elementar (A1)	Utilizador independente (B1)	Utilizador elementar (A1)	Utilizador elementar (A1)
Italiano	Utilizador elementar (A1)	Utilizador independente (B1)	Utilizador elementar (A1)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2001 Concluído	PhD in Engineering Sciences (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal "Biomimetic Natural Materials for Bone Regeneration" (TESE/DISSERTAÇÃO)	Approved
1993 Concluído	Engenharia Metalúrgica (Licenciatura) Universidade do Porto Faculdade de Engenharia, Portugal "Bioreactive Polymer/Ceramic Composites" (TESE/DISSERTAÇÃO)	14

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2018 - Atual	Investigador principal (carreira) (Investigação)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2013 - 2018	Investigador principal (carreira) (Investigação)	Instituto Nacional de Engenharia Biomédica, Portugal

2001 - 2013	Investigador (Investigação)	Instituto Nacional de Engenharia Biomédica, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2016/04/01 - 2017	Professor Associado (Docente Universitário)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

2016 - 2017	Professor Associado Convidado (Docente Universitário)	Universidade do Porto Faculdade de Engenharia, Portugal

2013 - 2017	Professor Auxiliar (Docente Universitário)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

2013 - 2017	Professor Visitante (Docente Universitário)	Universidade de Aveiro, Portugal

2005/01/01 - 2010	Assistente Convidado (Docente Universitário)	Universidade do Porto Faculdade de Engenharia, Portugal
	Universidade do Porto Faculdade de Engenharia, Portugal

Cargos e Funções

	Categoria Profissional Instituição de acolhimento	Empregador
1998 - Atual	Editor-in-Chief and Founder	Biomat.net, Portugal
	i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2014/01/01 - 2017	Board Member	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

2013/05/31 - 2017	Board member	Sociedade Portuguesa de Materiais, Portugal

2012/10/01 - 2017	Dirigente de laboratório, instituto, museu, centro ou observatório	Instituto Nacional de Engenharia Biomédica, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2012/03/01 - 2014/12/31	Coordinator of the NEWTherapies Group	Instituto Nacional de Engenharia Biomédica, Portugal

2006/03/01 - 2012/03/01	Deputy coordinator	Instituto Nacional de Engenharia Biomédica, Portugal

2007 - 2007	Invited Professor	Cité Internationale Universitaire de Paris, França

2004/01 - 2004/07	Visiting Assistant Research Scientist	University of Michigan, Estados Unidos

1998 - 2001	PhD student	INSERM, França

1994 - 2001	PhD student	Instituto Nacional de Engenharia Biomédica, Portugal

1992 - 1994	Teaching Assistant in laboratory courses	Universidade do Porto Faculdade de Engenharia, Portugal

Projetos

Bolsa

	Designação	Financiadores
2013 - 2015	Industrial biological biomaterials doctorate (IB2) IB2 Orientador INEB - Instituto de Engenharia Biomédica, Portugal	European Commission Concluído
2012 - 2013	Role of CD44 as a new mechanoreceptor ref Investigador responsável INEB - Instituto de Engenharia Biomédica, Portugal	Fundação Calouste Gulbenkian Concluído

Projeto

	Designação	Financiadores
2023/01/01 - Atual	Uncovering biomechanical drivers in skin fibrosis to engineer a novel biomimetic 3D tissue model (3DFibroSkin) 2022.06048.PTDC Investigador i3S - Instituto de Investigação e Inovação em Saúde, Portugal	Associação para a Inovação e Desenvolvimento da FCT Em curso
2023/01/09 - 2026/01/09	Instituto de biofabricación en red para el envejecimento saludable (IBEROS+) 0072_IBEROS_MAIS_1_E Investigador responsável	Em curso
2015 - 2018	In situ skin tissue engineering (SKINPRINT) PTDC/BBB-ECT/2145/2014 Investigador responsável i3S - Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2015 - 2018	SKINCHIP SKINCHIP Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2016 - 2017	Northern discoveries: The Discoveries CTR - Setting Sails. The Discoveries Centre for Regenerative and Precision Medicine Northern discoveries Investigador i3S - Instituto de Investigação e Inovação em Saúde, Portugal	NORTE2020 - North Region Operational Program Concluído
2015 - 2017	Bioengineered therapies for infectious diseases and tissue regeneration (BIOTHERAPIES) NORTE2020 Investigador responsável i3S - Instituto de Investigação e Inovação em Saúde, Portugal	NORTE2020 - North Region Operational Program Concluído
2015 - 2017	Bioengineering of soft tissues through placental extracellular matrices and stem cells of varied origins placental MSC Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Conselho Nacional de Desenvolvimento Científico e Tecnológico Concluído
2016/04 - 2016/11	Unraveling the combined influence of hypergravity, topography and biochemical cues on tendon cell behavior (ACHILES) achiles INEB - Instituto de Engenharia Biomédica, Portugal	European Space Agency (ESA) Concluído
2013 - 2016	Neuro-enhancement responsible research and innovation (NERRI) NERRI Investigador i3S - Instituto de Investigação e Inovação em Saúde, Portugal	European Commission Concluído
2013 - 2015	Integrated program on biomedical engineering for regenerative therapies and cancer (Deputy Coordinator) North Region Operational Program ON.2 INEB - Instituto de Engenharia Biomédica, Portugal	North Region Operational Program ON.2 Concluído
2013 - 2015	Development and biological evaluation of tissue engineered injectable systems Hungarian-Portuguese Intergovernmental S&T Cooperation Programme Investigador responsável INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2012 - 2015	Tumor-targeted nanoparticles for early diagnosis of gastric cancer (TUMORTAG) PTDC/CTM-NAN/120958/2010 Investigador responsável INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2014/04 - 2014/09	Influence of hypergravity on the formation of blood vessels by endothelial cells (ANGIOGRAVITY) Angiogravity Investigador responsável i3S - Instituto de Investigação e Inovação em Saúde, Portugal	European Space Agency (ESA) Concluído
2012 - 2014	Development of a biomaterial microarray for high-throughput screening of 3D cell cultures 3D cell cultures Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia
2011 - 2014	New materials for drug/gene delivery based on the self-assembly of dendrimer-chitosan-single stranded DNA (DENDRIMAT) DENDRIMAT Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2010 - 2013	Sr-Releasing injectable system for vertebroplasty (srHYBRID) srHYBRID Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2010 - 2013	Extracellular matrix-like multifunctional biomaterials for bone regeneration (BIOMATRIX) BIOMATRIX Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2008 - 2012	Novel biofunctional highly porous polymer scaffolds and techniques controlling angiogenesis for the regeneration and repair of the degenerated intervertebral disc (DISC REGENERATION) DISC REGENERATION Investigador INEB - Instituto de Engenharia Biomédica, Portugal	European Commission Concluído
2007 - 2010	Targeting nanoprobes for early detection of invasive cancer cells using hereditary diffuse gastric cancer as a model (NANOPROBE) NANOPROBE Investigador responsável INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007 - 2010	Design of new gene delivery vectors based on dendrimers, alginate and the RGD sequence for bone tissue engineering (DENDRALGENE) DENDRALGENE Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007 - 2009	Bridging biomaterial research excellence between industry and academia across Europe (BRIDGE) BRIDGE Instituto Nacional de Engenharia Biomédica, Portugal	European Commission Concluído
2005 - 2008	Bone regeneration by stimulation of angiogenesis (ANGIO) ANGIO Investigador responsável INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2004 - 2006	Core Laboratories for the Improvement of medical devices in clinical practice from the failure of the explanted prostheses analysis (FEPA) FEPA Investigador INEB - Instituto de Engenharia Biomédica, Portugal	European Commission Concluído
2003/05/02 - 2006	An injectable enzyme delivery system based on apatite nanoparticles and natural hydrogel microspheres for bone regeneration info:eu-repo/grantAgreement/FCT/POCI/41523/PT Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2004/01 - 2004/12	Microencapsulation systems for cotransplantation ref Investigador responsável INEB - Instituto de Engenharia Biomédica, Portugal	Fundação Luso-Americana Concluído
2001 - 2002	Novel intervertebral disc prostheses (DISC) (Deputy Coordinator of INEB’s team) DISC Bolseiro de Pós-Doutoramento INEB - Instituto de Engenharia Biomédica, Portugal	European Commission Concluído
2001 - 2002	Development of cellulosic biomaterials for bone regeneration biomaterials for bone regeneration Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
1999 - 2001	Bioactive biomaterials as supports for the immobilisation and subsquent in vivo release of imiglucerase: A new therapeutic approach for the treatment of Gaucher Disease Gaucher Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
1999 - 2001	Tailoring of biomaterials at the nanoscale: Applications in bone surgery and heamotherapy ref Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Bilateral Cooperation between Portugal (ICCTI) and R. P. China (Ministry of Science and Technology) Concluído
1998 - 2000	Medical devices for collecting, processing and storing blood and blood constituents (CARE) CARE Bolseiro de Pós-Doutoramento INEB - Instituto de Engenharia Biomédica, Portugal	Ministério da Economia Concluído
1997 - 2000	Biomineralization of implant materials (BIOMINERAL) BIOMINERAL Investigador INEB - Instituto de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
1995 - 1996	Biomatériaux et suppléance fonctionelle Biomatériaux Investigador INSERM, França	Association Génie Biologique et Médical (GBM) Aquitaine Concluído

Produções

Publicações

Artigo em conferência	Crisóstomo, J.; Araújo, F.; Granja, P.; Barrias, C.; Sarmento, B.; Seiça, R.. "Co-encapsulation of Beta Cells and Nanoparticles Containing GLP-1 Greatly Improves Insulin Secretion in Alginate-Based Bioartificial Pancreas". 2020. 10.1007/978-3-030-31635-8_147 Costa-Almeida, Raquel; Carvalho, Daniel T. O.; Ferreira, Miguel J. S.; Pesqueira, Tamagno; Monici, Monica; van Loon, Jack J. W. A.; Granja, Pedro L.; Gomes, Manuela E.. "Simulated hypergravity induces changes in human tendon-derived cells: from cell morphology to gene expression". 2017. Venckevicius, R.; Kašalynas, I.; Wahaia, F.; Urbanovic, A.; Molis, G.; Seliuta, D.; Valušis, G.; et al. "Terahertz imaging of carcinoma-affected colon tissues fixed in paraffin". 2015. 10.1109/IRMMW-THz.2015.7327457 Wahaia, F.; Kasalynas, I.; Seliuta, D.; Molis, G.; Urbanowicz, A.; Silva, C.D.C.; Carneiro, F.; Valusis, G.; Granja, P.L.. "Study of gastric cancer samples using terahertz techniques". 2014. 10.1117/12.2063463 Munarin, F.; Grellier, M.; Lamghari, M.; Tanzi, M.C.; Barbosa, M.A.; Petrini, P.; Granja, P.L.. "Rgd-grafted pectin microspheres for human mesenchymal stem cell delivery and in situ bone regeneration". 2011. Bidarra, S.J.; Barrias, C.C.; Fonseca, K.B.; Barbosa, M.A.; Soares, R.; Granja, P.L.. "In vitro potential of a natural injectable RGD-alginate hydrogel to deliver endothelial cells". 2011. Grellier, M.; Bidarra, S.J.; Bareille, R.; Granja, P.L.; Barbosa, M.A.; Amédée, J.. "Cell encapsulation for vascularized bone tissue engineering". 2008. Guerreiro, S.; Bidarra, S.J.; Evangelista, M.B.; Barrias, C.C.; Barbosa, M.A.; Soares, R.; Granja, P.L.. "Immobilization of human endothelial cells within RGD-grafted alginate". 2008. Santos, J.; Oramas, E.; Pêgo, A.; Granja, P.; Tomás, H.. "In vitro osteoblastic differentiation of MSCs using PAMAM dendrimers as delivery vectors for the hBMP-2 gene". 2008. Evangelista, M.B.; Silva, E.A.; Kim, E.-S.; L. Granja, P.; J. Mooney, D.. "Influence of different human endothelial cell populations on osteoprogenitors differentiation". 2008. Salgado, C.; Sanchez, E.; Zavaglia, C.; Granja, P.L.. "Injectable polymeric matrices for bone tissue engineering". 2008. Bidarra, S.J.; Barrias, C.C.; Mooney, D.J.; Barbosa, M.A.; Soares, R.; Granja, P.L.. "Immobilization of mesenchymal stem cells within RGD-grafted alginate". 2008. CUNHA, AM; REIS, RL; FERREIRA, FG; GRANJA, PL. "The influence of processing conditions on the mechanical behaviour of UHMWPE/HA and PMMA/HA composites". 1995. 10.1007/978-94-011-0157-8_11
Artigo em revista	M. Manuela Brás; Aureliana Sousa; Tânia B. Cruz; Jonas Michalewski; Marina Leite; Susana R. Sousa; Pedro L. Granja; Manfred Radmacher. "Microrheological comparison of melanoma cells by atomic force microscopy". Journal of Biological Physics (2024): https://doi.org/10.1007/s10867-023-09648-w. 10.1007/s10867-023-09648-w Brás MM, Sousa A, Cruz TB, Michalewski J, Leite M, Sousa SR, Granja PL, Radmacher M. "Microrheological comparison melanoma cells using dynamic atomic force microscopy". J Biol Phys (2024): Publicado Daniel A. Ferreira; João P. Conde; Mario Rothbauer; Peter Ertl; Pedro L. Granja; Carla Oliveira. "Bioinspired human stomach-on-a-chip with in vivo like function and architecture". Lab on a Chip (2023): https://doi.org/10.1039/D2LC01132H. 10.1039/D2LC01132H Redondo M, Presa R, Granja PL, Araújo M, Sousa A. "Konjac glucomannan photocrosslinked hydrogels for in vitro 3D cell culture". Mater Today Chem 34. (2023): 101761. M. Manuela Brás; Tânia B. Cruz; André F. Maia; Maria José Oliveira; Susana R. Sousa; Pedro L. Granja; Manfred Radmacher. "Mechanical Properties of Colorectal Cancer Cells Determined by Dynamic Atomic Force Microscopy: A Novel Biomarker". Cancers (2022): https://doi.org/10.3390/cancers14205053. 10.3390/cancers14205053 Daniel A. Ferreira; Mario Rothbauer; João P. Conde; Peter Ertl; Carla Oliveira; Pedro L. Granja. "A Fast Alternative to Soft Lithography for the Fabrication of Organ-on-a-Chip Elastomeric-Based Devices and Microactuators". Advanced Science (2021): https://doi.org/10.1002/advs.202003273. 10.1002/advs.202003273 Susana G. Guerreiro; Ronald E. Unger; Nuno M. F. S. A. Cerqueira; Anne Sartoris; Maria J. Martins; Mário A. Barbosa; Raquel Soares; Pedro L. Granja; Charles J. Kirkpatrick. "Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro". Journal of Cellular Biochemistry (2021): https://doi.org/10.1002/jcb.29835. 10.1002/jcb.29835 Ribeiro, Nilza; Sousa, Aureliana; Cunha-Reis, Cassilda; Oliveira, Ana Leite; Granja, Pedro L.; Monteiro, Fernando J.; Sousa, Susana. "New prospects in skin regeneration and repair using nanophased hydroxyapatite embedded in collagen nanofibers". (2021): http://hdl.handle.net/10400.14/31685. 10.1016/j.nano.2020.102353 Lourenco, BN; Pereira, RF; Barrias, CC; Fischbach, C; Oliveira, C; Granja, PL. "Engineering Modular Half-Antibody Conjugated Nanoparticles for Targeting CD44v6-Expressing Cancer Cells". NANOMATERIALS (2021): 10.3390/nano11020295 Carla Pereira; Daniel Ferreira; Nuno Mendes; Pedro L. Granja; Gabriela M. Almeida; Carla Oliveira. "Expression of CD44v6-Containing Isoforms Influences Cisplatin Response in Gastric Cancer Cells". Cancers (2020): https://doi.org/10.3390/cancers12040858. Publicado • 10.3390/cancers12040858 Melo, S.F.; Neves, S.C.; Pereira, A.T.; Borges, I.; Granja, P.L.; Magalhães, F.D.; Gonçalves, I.C.. "Incorporation of graphene oxide into poly(¿-caprolactone) 3D printed fibrous scaffolds improves their antimicrobial properties". Materials Science and Engineering C 109 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85077755863&partnerID=MN8TOARS. 10.1016/j.msec.2019.110537 Neves, Sara C.; Moroni, Lorenzo; Barrias, Cristina C.; Granja, Pedro L.. "Leveling Up Hydrogels: Hybrid Systems in Tissue Engineering". Trends in Biotechnology 38 3 (2020): 292-315. https://publons.com/publon/31187701/. Publicado • 10.1016/J.TIBTECH.2019.09.004 Granja, Pedro L.; Bauleth-Ramos, T.; Feijão, T.; Gonçalves, A.; Shahbazi, M.-A.; Liu, Z.; Barrias, C.; et al. "Colorectal cancer triple co -culture spheroid model to assess the biocompatibility and anticancer properties of polymeric nanoparticles". Journal of Controlled Release 323 (2020): 398-411. https://publons.com/publon/34814720/. 10.1016/j.jconrel.2020.04.025 Crisóstomo, J.; Araújo, F.; Granja, P.; Barrias, C.; Sarmento, B.; Seiça, R.. "Increasing levels of insulin secretion in bioartificial pancreas technology: co-encapsulation of beta cells and nanoparticles containing GLP-1 in alginate hydrogels". Health and Technology (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85083827298&partnerID=MN8TOARS. 10.1007/s12553-020-00427-4 Calçada, Carla Sofia Martins; Silva, Miguel; Baptista, Vitória; Thathy, Vandana; Pedrosa, Ana; Granja, Diana; Ferreira, Pedro Eduardo; et al. "Expansion of a specific plasmodium falciparum PfMDR1 Haplotype in southeast Asia with increased substrate transport". (2020): http://hdl.handle.net/1822/70933. 10.1128/mBio.02093-20 Brás, M. Manuela; Radmacher, Manfred; Sousa, Susana R.; Granja, Pedro L.; Bras, M. Manuela. "Melanoma in the Eyes of Mechanobiology". Frontiers in Cell and Developmental Biology (2020): http://hdl.handle.net/10400.22/19464. 10.3389/fcell.2020.00054 Pereira, S.B.; Sousa, A.; Santos, M.; Araújo, M.; Serôdio, F.; Granja, P.; Tamagnini, P.. "Strategies to obtain designer polymers based on cyanobacterial extracellular polymeric substances (EPS)". International Journal of Molecular Sciences 20 22 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85075114328&partnerID=MN8TOARS. 10.3390/ijms20225693 Crisóstomo, J.; Pereira, A.M.; Bidarra, S.J.; Gonçalves, A.C.; Granja, P.L.; Coelho, J.F.J.; Barrias, C.C.; Seiça, R.. "ECM-enriched alginate hydrogels for bioartificial pancreas: an ideal niche to improve insulin secretion and diabetic glucose profile". Journal of Applied Biomaterials and Functional Materials 17 4 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85073602290&partnerID=MN8TOARS. 10.1177/2280800019848923 Flores, Carlos; Lima, Raquel T.; Adessi, Alessandra; Sousa, Aureliana; Pereira, Sara B.; Granja, Pedro L.; De Philippis, Roberto; et al. "Characterization and antitumor activity of the extracellular carbohydrate polymer from the cyanobacterium Synechocystis Delta sigF mutant". International Journal of Biological Macromolecules 136 (2019): 1219-1227. https://publons.com/publon/27038951/. 10.1016/J.IJBLOMAC.2019.06.152 Neves, M.I.; Araújo, M.; Barrias, C.C.; Granja, P.L.; Sousa, A.. "Multiplatform Protein Detection and Quantification Using Glutaraldehyde-Induced Fluorescence for 3D Systems". Journal of Fluorescence 29 5 (2019): 1171-1181. http://www.scopus.com/inward/record.url?eid=2-s2.0-85073924791&partnerID=MN8TOARS. 10.1007/s10895-019-02433-w Marques, C.F.; Olhero, S.M.; Torres, P.M.C.; Abrantes, J.C.C.; Fateixa, S.; Nogueira, H.I.S.; Ribeiro, I.A.C.; et al. "Novel sintering-free scaffolds obtained by additive manufacturing for concurrent bone regeneration and drug delivery: Proof of concept". Materials Science and Engineering C 94 (2019): 426-436. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053772854&partnerID=MN8TOARS. 10.1016/j.msec.2018.09.050 Pereira, Sara B.; Sousa, Aureliana; Santos, Marina; Araujo, Marco; Serodio, Filipa; Granja, Pedro; Tamagnini, Paula. "Strategies to Obtain Designer Polymers Based on Cyanobacterial Extracellular Polymeric Substances (EPS)". International Journal of Molecular Sciences (2019): https://publons.com/publon/28926514/. 10.3390/IJMS20225693 Bauleth-Ramos, T.; Shih, T.-Y.; Shahbazi, M.-A.; Najibi, A.J.; Mao, A.S.; Liu, D.; Granja, P.; et al. "Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination". Advanced Functional Materials 29 35 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85068179169&partnerID=MN8TOARS. 10.1002/adfm.201903686 Serôdio, Ricardo; Schickert, Sónia L.; Costa-Pinto, Ana R.; Dias, Juliana R.; Granja, Pedro L.; Yang, Fang; Oliveira, Ana L.. "Ultrasound sonication prior to electrospinning tailors silk fibroin/PEO membranes for periodontal regeneration". (2019): http://hdl.handle.net/10400.14/26788. 10.1016/j.msec.2019.01.055 E. Bauman; P.L. Granja; C.C. Barrias. "Fetal bovine serum-free culture of endothelial progenitor cells-progress and challenges". Journal of Tissue Engineering and Regenerative Medicine (2018): https://doi.org/10.1002/term.2678. 10.1002/term.2678 Rúben F. Pereira; Aureliana Sousa; Cristina C. Barrias; Paulo J. Bártolo; Pedro L. Granja; Pereira, R.F.; Sousa, A.; et al. "A single-component hydrogel bioink for bioprinting of bioengineered 3D constructs for dermal tissue engineering". Materials Horizons 5 6 (2018): 1100-1111. https://doi.org/10.1039/C8MH00525G. 10.1039/C8MH00525G Bianca N. Lourenço; Nora L. Springer; Daniel Ferreira; Carla Oliveira; Pedro L. Granja; Claudia Fischbach; Lourenço, B.N.; et al. "CD44v6 increases gastric cancer malignant phenotype by modulating adipose stromal cell-mediated ECM remodeling". Integrative Biology 10 3 (2018): 145-158. https://doi.org/10.1039/C7IB00179G. 10.1039/C7IB00179G Costa-Almeida, R.; Carvalho, D.T.O.; Ferreira, M.J.S.; Pesqueira, T.; Monici, M.; Van Loon, J.J.W.A.; Granja, P.L.; Gomes, M.E.. "Continuous exposure to simulated hypergravity-induced changes in proliferation, morphology, and gene expression of human tendon cells". Stem Cells and Development 27 12 (2018): 858-869. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048374590&partnerID=MN8TOARS. 10.1089/scd.2017.0206 Kennedy, P.J.; Sousa, F.; Ferreira, D.; Pereira, C.; Nestor, M.; Oliveira, C.; Granja, P.L.; et al. "Fab-conjugated PLGA nanoparticles effectively target cancer cells expressing human CD44v6". Acta Biomaterialia 81 (2018): 208-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054155176&partnerID=MN8TOARS. 10.1016/j.actbio.2018.09.043 Kennedy, P.J.; Perreira, I.; Ferreira, D.; Nestor, M.; Oliveira, C.; Granja, P.L.; Sarmento, B.; et al. "Impact of surfactants on the target recognition of Fab-conjugated PLGA nanoparticles". European Journal of Pharmaceutics and Biopharmaceutics 127 (2018): 366-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043984392&partnerID=MN8TOARS. 10.1016/j.ejpb.2018.03.005 Dias, J. R.; Baptista-Silva, S.; Sousa, A.; Oliveira, A. L.; Bartolo, P. J.; Granja, P. L.; Dias, J.R.; et al. "Biomechanical performance of hybrid electrospun structures for skin regeneration". Materials Science and Engineering: C 93 (2018): 816-827. https://publons.com/publon/20969009/. 10.1016/J.MSEC.2018.08.050 Lourenco, Bianca N.; dos Santos, Tiago; Oliveira, Carla; Barrias, Cristina C.; Granja, Pedro L.; Lourenço, B.N.; dos Santos, T.; et al. "Bioengineering a novel 3D in vitro model of gastric mucosa for stomach permeability studies". Acta Biomaterialia 82 (2018): 68-78. https://publons.com/publon/30400989/. 10.1016/J.ACTBIO.2018.10.007 Singh, Poonam; Medronho, Bruno; dos Santos, Tiago; Nunes-Correia, Isabel; Granja, Pedro; Miguel, Maria G.; Lindman, Bjoern; et al. "On the viability, cytotoxicity and stability of probiotic bacteria entrapped in cellulose-based particles". Food Hydrocolloids 82 (2018): 457-465. https://publons.com/publon/24865828/. 10.1016/J.FOODHYD.2018.04.027 Pereira, Rui F. P.; Zehbe, Kerstin; Guenter, Christina; dos Santos, Tiago; Nunes, Silvia C.; Almeida Paz, Filipe A.; Silva, Maria M.; et al. "Ionic Liquid-Assisted Synthesis of Mesoporous Silk Fibroin/Silica Hybrids for Biomedical Applications". ACS Omega 3 9 (2018): 10811-10822. https://publons.com/publon/10838820/. 10.1021/ACSOMEGA.8B02051 Costa-Almeida, Raquel; Carvalho, Daniel T. O.; Ferreira, Miguel J. S.; Pesqueira, Tamagno; Monici, Monica; van Loon, Jack J. W. A.; Granja, Pedro L.; Gomes, Manuela E.. "Continuous Exposure to Simulated Hypergravity-Induced Changes in Proliferation, Morphology, and Gene Expression of Human Tendon Cells". Stem Cells and Development (2018): https://publons.com/publon/1652599/. 10.1089/SCD.2017.0206 Bauman, E.; Feijão, T.; Carvalho, D.T.O.; Granja, P.L.; Barrias, C.C.; Feijao, T.; Carvalho, D. T. O.; Granja, P. L.; Barrias, C. C.. "Xeno-free pre-vascularized spheroids for therapeutic applications". Scientific Reports 8 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040445656&partnerID=MN8TOARS. 10.1038/s41598-017-18431-6 Pereira, Rui Francisco Gonçalves Pinto Fernandes; Zehbe, Kerstin; Guenter, Christina; dos Santos, Tiago; Nunes, Silvia C.; Almeida Paz, Filipe A.; Silva, Maria Manuela; et al. "Ionic liquid-assisted synthesis of mesoporous silk fibroin/silica hybrids for biomedical applications". (2018): http://hdl.handle.net/1822/72884. 10.1021/acsomega.8b02051 Silva, E. D.; Babo, Pedro Miguel Sousa; Costa-Almeida, R.; Domingues, R. M. A.; Mendes, B. B.; Paz, E.; Freitas, P.; et al. "Multifunctional magnetic-responsive hydrogels to engineer tendon-to-bone interface". Nanomedicine: Nanotechnology, Biology, and Medicine (2018): http://hdl.handle.net/1822/64839. 10.1016/j.nano.2017.06.002 Costa-Almeida, R.; Soares, R.; Granja, P.L.. "Fibroblasts as maestros orchestrating tissue regeneration". Journal of Tissue Engineering and Regenerative Medicine (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85019570228&partnerID=MN8TOARS. 10.1002/term.2405 Neves, M.I.; Wechsler, M.E.; Gomes, M.E.; Reis, R.L.; Granja, P.L.; Peppas, N.A.. "Molecularly Imprinted Intelligent Scaffolds for Tissue Engineering Applications". Tissue Engineering - Part B: Reviews 23 1 (2017): 27-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-85024406982&partnerID=MN8TOARS. 10.1089/ten.teb.2016.0202 Pereira, R.F.; Barrias, C.C.; Bártolo, P.J.; Granja, P.L.. "Cell-instructive pectin hydrogels crosslinked via thiol-norbornene photo-click chemistry for skin tissue engineering". Acta Biomaterialia (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85034850058&partnerID=MN8TOARS. 10.1016/j.actbio.2017.11.016 Bauleth-Ramos, T.; Shahbazi, M.-A.; Liu, D.; Fontana, F.; Correia, A.; Figueiredo, P.; Zhang, H.; et al. "Nutlin-3a and Cytokine Co-loaded Spermine-Modified Acetalated Dextran Nanoparticles for Cancer Chemo-Immunotherapy". Advanced Functional Materials 27 42 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85028762962&partnerID=MN8TOARS. 10.1002/adfm.201703303 Kennedy, P.J.; Oliveira, C.; Granja, P.L.; Sarmento, B.. "Monoclonal antibodies: technologies for early discovery and engineering". Critical Reviews in Biotechnology (2017): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027194652&partnerID=MN8TOARS. 10.1080/07388551.2017.1357002 Araújo, F.; das Neves, J.; Martins, J.P.; Granja, P.L.; Santos, H.A.; Sarmento, B.. "Functionalized materials for multistage platforms in the oral delivery of biopharmaceuticals". Progress in Materials Science 89 (2017): 306-344. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020029869&partnerID=MN8TOARS. 10.1016/j.pmatsci.2017.05.001 Dias, J.R.; Baptista-Silva, S.; Oliveira, C.M.T.D.; Sousa, A.; Oliveira, A.L.; Bártolo, P.J.; Granja, P.L.. "In situ crosslinked electrospun gelatin nanofibers for skin regeneration". European Polymer Journal 95 (2017): 161-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026912199&partnerID=MN8TOARS. 10.1016/j.eurpolymj.2017.08.015 Kennedy, P.J.; Oliveira, C.; Granja, P.L.; Sarmento, B.. "Antibodies and associates: Partners in targeted drug delivery". Pharmacology and Therapeutics 177 (2017): 129-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016399420&partnerID=MN8TOARS. 10.1016/j.pharmthera.2017.03.004 Costa-Almeida, R.; Granja, P.L.; Gomes, M.E.. "Gravity, Tissue Engineering, and the Missing Link". Trends in Biotechnology (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85034606920&partnerID=MN8TOARS. 10.1016/j.tibtech.2017.10.017 Dias, J.R.; dos Santos, C.; Horta, J.; Granja, P.L.; Bártolo, P.J.. "A new design of an electrospinning apparatus for tissue engineering applications". International Journal of Bioprinting 3 2 (2017): 121-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045296163&partnerID=MN8TOARS. 10.18063/IJB.2017.02.002 Wahaia, F.; Kasalynas, I.; Venckevicius, R.; Seliuta, D.; Valusis, G.; Urbanowicz, A.; Molis, G.; et al. "Terahertz absorption and reflection imaging of carcinoma-affected colon tissues embedded in paraffin". Journal of Molecular Structure 1107 (2016): 214-219. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948845569&partnerID=MN8TOARS. 10.1016/j.molstruc.2015.11.048 Araújo, F.; Pereira, C.; Costa, J.; Barrias, C.; Granja, P.L.; Sarmento, B.. "In vitro M-like cells genesis through a tissue-engineered triple-culture intestinal model". Journal of Biomedical Materials Research - Part B Applied Biomaterials 104 4 (2016): 782-788. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940689050&partnerID=MN8TOARS. 10.1002/jbm.b.33508 Araújo, F.; Shrestha, N.; Gomes, M.J.; Herranz-Blanco, B.; Liu, D.; Hirvonen, J.J.; Granja, P.L.; Santos, H.A.; Sarmento, B.. "In vivo dual-delivery of glucagon like peptide-1 (GLP-1) and dipeptidyl peptidase-4 (DPP4) inhibitor through composites prepared by microfluidics for diabetes therapy". Nanoscale 8 20 (2016): 10706-10713. http://www.scopus.com/inward/record.url?eid=2-s2.0-84971265278&partnerID=MN8TOARS. 10.1039/c6nr00294c Branco da Cunha, C.; Klumpers, D.D.; Koshy, S.T.; Weaver, J.C.; Chaudhuri, O.; Seruca, R.; Carneiro, F.; Granja, P.L.; Mooney, D.J.. "CD44 alternative splicing in gastric cancer cells is regulated by culture dimensionality and matrix stiffness". Biomaterials 98 (2016): 152-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-84966708392&partnerID=MN8TOARS. 10.1016/j.biomaterials.2016.04.016 Costa-Almeida, R.; Carvalho, D.T.O.; Ferreira, M.J.S.; Aresta, G.; Gomes, M.E.; Van Loon, J.J.W.A.; Van Der Heiden, K.; Granja, P.L.. "Effects of hypergravity on the angiogenic potential of endothelial cells". Journal of the Royal Society Interface 13 124 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85006157200&partnerID=MN8TOARS. 10.1098/rsif.2016.0688 Neves, S.C.; Mota, C.; Longoni, A.; Barrias, C.C.; Granja, P.L.; Moroni, L.. "Additive manufactured polymeric 3D scaffolds with tailored surface topography influence mesenchymal stromal cells activity". Biofabrication 8 2 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84987677248&partnerID=MN8TOARS. 10.1088/1758-5090/8/2/025012 Dias, J.R.; Granja, P.L.; Bártolo, P.J.. "Advances in electrospun skin substitutes". Progress in Materials Science 84 (2016): 314-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992128552&partnerID=MN8TOARS. 10.1016/j.pmatsci.2016.09.006 Granja, P. L.. "Molecularly designed hydrogels as 3D cellular microenvironments". The FEBS Journal (2016): https://publons.com/publon/31187706/. Costa-Almeida, R.; Gomez-Lazaro, M.; Ramalho, C.; Granja, P.L.; Soares, R.; Guerreiro, S.G.. "Fibroblast-endothelial partners for vascularization strategies in tissue engineering". Tissue Engineering - Part A 21 5-6 (2015): 1055-1065. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924404743&partnerID=MN8TOARS. 10.1089/ten.tea.2014.0443 Araújo, F.; Shrestha, N.; Granja, P.L.; Hirvonen, J.; Santos, H.A.; Sarmento, B.. "Safety and toxicity concerns of orally delivered nanoparticles as drug carriers". Expert Opinion on Drug Metabolism and Toxicology 11 3 (2015): 381-393. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922975886&partnerID=MN8TOARS. 10.1517/17425255.2015.992781 Kapoor, S.; Semitela, Â.; Goel, A.; Xiang, Y.; Du, J.; Lourenço, A.H.; Sousa, D.M.; Granja, P.L.; Ferreira, J.M.F.. "Understanding the composition-structure-bioactivity relationships in diopside (CaO·MgO·2SiO2)-tricalcium phosphate (3CaO·P2O5) glass system". Acta Biomaterialia 15 (2015): 210-226. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922677729&partnerID=MN8TOARS. 10.1016/j.actbio.2015.01.001 Pereira, C.; Araújo, F.; Barrias, C.C.; Granja, P.L.; Sarmento, B.. "Dissecting stromal-epithelial interactions in a 3D invitro cellularized intestinal model for permeability studies". Biomaterials 56 (2015): 36-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928394450&partnerID=MN8TOARS. 10.1016/j.biomaterials.2015.03.054 Wahaia, F.; Kasalynas, I.; Seliuta, D.; Molis, G.; Urbanowicz, A.; Carvalho Silva, C.D.; Carneiro, F.; Valusis, G.; Granja, P.L.. "Terahertz spectroscopy for the study of paraffin-embedded gastric cancer samples". Journal of Molecular Structure 1079 (2015): 391-395. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908193837&partnerID=MN8TOARS. 10.1016/j.molstruc.2014.09.002 Wahaia, F.; Kasalynas, I.; Seliuta, D.; Molis, G.; Urbanowicz, A.; Carvalho Silva, C.D.; Carneiro, F.; Valusis, G.; Granja, P.L.. "Study of paraffin-embedded colon cancer tissue using terahertz spectroscopy". Journal of Molecular Structure 1079 (2015): 448-453. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908191771&partnerID=MN8TOARS. 10.1016/j.molstruc.2014.09.024 Araujo, F; Shrestha, N; Shahbazi, MA; Liu, DF; Herranz Blanco, B; Makila, EM; Salonen, JJ; et al. "Microfluidic Assembly of a Multifunctional Tailorable Composite System Designed for Site Specific Combined Oral Delivery of Peptide Drugs". ACS NANO (2015): 10.1021/acsnano.5b02762 Vieira, Sílvia; Vial, Stéphanie; Maia, F. Raquel; Carvalho, Mariana R.; Reis, R. L.; Granja, Pedro L.; Oliveira, Joaquim Miguel Antunes Correia; et al. "Gellan gum-coated gold nanorods: an intracellular nanosystem for bone tissue engineering". RSC ADVANCES (2015): http://hdl.handle.net/1822/40294. 10.1039/C5RA13556G Vieira, S.; Vial, S.; Maia, R.; Carvalho, M.; Reis, R. L.; Granja, P. L.; Oliveira, J. M.. "Gellan Gum-coated Gold Nanorods as Nanotools for Bone Tissue Engineering". Tissue Engineering Part A (2015): https://publons.com/publon/3424864/. Neves, S.C.; Gomes, D.B.; Sousa, A.; Bidarra, S.J.; Petrini, P.; Moroni, L.; Barrias, C.C.; et al. "Biofunctionalized pectin hydrogels as 3D cellular microenvironments". Journal of Materials Chemistry B 3 10 (2015): 2096-2108. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923913719&partnerID=MN8TOARS. 10.1039/c4tb00885e Costa-Almeida, R.; Granja, P.L.; Soares, R.; Guerreiro, S.G.. "Cellular strategies to promote vascularisation in tissue engineering applications". European Cells and Materials 28 (2014): 51-67. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904957526&partnerID=MN8TOARS. Maia, F.R.; Barbosa, M.; Gomes, D.B.; Vale, N.; Gomes, P.; Granja, P.L.; Barrias, C.C.. "Hydrogel depots for local co-delivery of osteoinductive peptides and mesenchymal stem cells". Journal of Controlled Release 189 (2014): 158-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904318888&partnerID=MN8TOARS. 10.1016/j.jconrel.2014.06.030 Vasconcelos, D.M.; Falentin-Daudré, C.; Blanquaert, D.; Thomas, D.; Granja, P.L.; Migonney, V.. "Role of protein environment and bioactive polymer grafting in the S. epidermidis response to titanium alloy for biomedical applications". Materials Science and Engineering C 45 (2014): 176-183. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907482809&partnerID=MN8TOARS. 10.1016/j.msec.2014.08.054 Guerreiro, S.G.; Oliveira, M.J.; Barbosa, M.A.; Soares, R.; Granja, P.L.. "Neonatal human dermal fibroblasts immobilized in RGD-alginate induce angiogenesis". Cell Transplantation 23 8 (2014): 945-957. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905231059&partnerID=MN8TOARS. 10.3727/096368913X670183 Araújo, F.; Shrestha, N.; Shahbazi, M.-A.; Fonte, P.; Mäkilä, E.M.; Salonen, J.J.; Hirvonen, J.T.; et al. "The impact of nanoparticles on the mucosal translocation and transport of GLP-1 across the intestinal epithelium". Biomaterials 35 33 (2014): 9199-9207. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906788144&partnerID=MN8TOARS. 10.1016/j.biomaterials.2014.07.026 Araújo, F.; Shrestha, N.; Granja, P.L.; Hirvonen, J.; Santos, H.A.; Sarmento, B.. "Antihyperglycemic potential of incretins orally delivered via nano and microsystems and subsequent glucoregulatory effects". Current Pharmaceutical Biotechnology 15 7 (2014): 609-619. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925868886&partnerID=MN8TOARS. Branco da Cunha, C.; Klumpers, D.D.; Li, W.A.; Koshy, S.T.; Weaver, J.C.; Chaudhuri, O.; Granja, P.L.; Mooney, D.J.. "Influence of the stiffness of three-dimensional alginate/collagen-I interpenetrating networks on fibroblast biology". Biomaterials 35 32 (2014): 8927-8936. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905723265&partnerID=MN8TOARS. 10.1016/j.biomaterials.2014.06.047 Fonseca, K.B.; Granja, P.L.; Barrias, C.C.. "Engineering proteolytically-degradable artificial extracellular matrices". Progress in Polymer Science 39 12 (2014): 2010-2029. http://www.scopus.com/inward/record.url?eid=2-s2.0-84910642434&partnerID=MN8TOARS. 10.1016/j.progpolymsci.2014.07.003 Pereira, C.; Araújo, F.; Granja, P.L.; Santos, H.A.; Sarmento, B.. "Targeting membrane transporters and receptors as a mean to optimize orally delivered biotechnological based drugs through nanoparticle delivery systems". Current Pharmaceutical Biotechnology 15 7 (2014): 650-658. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925871696&partnerID=MN8TOARS. Fonseca, K.B.; Gomes, D.B.; Lee, K.; Santos, S.G.; Sousa, A.; Silva, E.A.; Mooney, D.J.; Granja, P.L.; Barrias, C.C.. "Injectable MMP-sensitive alginate hydrogels as hMSC delivery systems". Biomacromolecules 15 1 (2014): 380-390. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892606344&partnerID=MN8TOARS. 10.1021/bm4016495 Moreira, H.R.; Munarin, F.; Gentilini, R.; Visai, L.; Granja, P.L.; Tanzi, M.C.; Petrini, P.. "Injectable pectin hydrogels produced by internal gelation: PH dependence of gelling and rheological properties". Carbohydrate Polymers 103 1 (2014): 339-347. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892575017&partnerID=MN8TOARS. 10.1016/j.carbpol.2013.12.057 Maia, F.R.; Fonseca, K.B.; Rodrigues, G.; Granja, P.L.; Barrias, C.C.. "Matrix-driven formation of mesenchymal stem cell-extracellular matrix microtissues on soft alginate hydrogels". Acta Biomaterialia 10 7 (2014): 3197-3208. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901785690&partnerID=MN8TOARS. 10.1016/j.actbio.2014.02.049 Maia, F.R.; Lourenço, A.H.; Granja, P.L.; Gonçalves, R.M.; Barrias, C.C.. "Effect of cell density on mesenchymal stem cells aggregation in RGD-alginate 3D matrices under osteoinductive conditions". Macromolecular Bioscience 14 6 (2014): 759-771. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902536382&partnerID=MN8TOARS. 10.1002/mabi.201300567 Bidarra, S.J.; Barrias, C.C.; Granja, P.L.. "Injectable alginate hydrogels for cell delivery in tissue engineering". Acta Biomaterialia 10 4 (2014): 1646-1662. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896403229&partnerID=MN8TOARS. 10.1016/j.actbio.2013.12.006 Almeida, R.; Lazaro, M.; Soares, R.; Guerreiro, S.; Granja, P.. "Interactions between dermal fibroblasts and endothelial cells in vascularization for tissue engineering applications". Journal of Tissue Engineering and Regenerative Medicine (2014): https://publons.com/publon/12183286/. Pereira, R.F.; Barrias, C.C.; Granja, P.L.; Bartolo, P.J.. "Advanced biofabrication strategies for skin regeneration and repair". Nanomedicine 8 4 (2013): 603-621. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875943184&partnerID=MN8TOARS. 10.2217/nnm.13.50 Fonseca, K.B.; Maia, F.R.; Cruz, F.A.; Andrade, D.; Juliano, M.A.; Granja, P.L.; Barrias, C.C.. "Enzymatic, physicochemical and biological properties of MMP-sensitive alginate hydrogels". Soft Matter 9 12 (2013): 3283-3292. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874428389&partnerID=MN8TOARS. 10.1039/c3sm27560d Maia, F.R.; Bidarra, S.J.; Granja, P.L.; Barrias, C.C.. "Functionalization of biomaterials with small osteoinductive moieties". Acta Biomaterialia 9 11 (2013): 8773-8789. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885024380&partnerID=MN8TOARS. 10.1016/j.actbio.2013.08.004 Salgado, C.L.; Sanchez, E.M.S.; Zavaglia, C.A.C.; Granja, P.L.. "Biocompatibility and biodegradation of polycaprolactone-sebacic acid blended gels". Journal of Biomedical Materials Research - Part A 100 A 1 (2012): 243-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-81955165189&partnerID=MN8TOARS. 10.1002/jbm.a.33272 Munarin, F.; Petrini, P.; Tanzi, M.C.; Barbosa, M.A.; Granja, P.L.. "Biofunctional chemically modified pectin for cell delivery". Soft Matter 8 17 (2012): 4731-4739. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859741806&partnerID=MN8TOARS. 10.1039/c2sm07260b Guerreiro, S.G.; Brochhausen, C.; Negrão, R.; Barbosa, M.A.; Unger, R.E.; Kirkpatrick, C.J.; Soares, R.; Granja, P.L.. "Implanted neonatal human dermal fibroblasts influence the recruitment of endothelial cells in mice.". Biomatter 2 1 (2012): 43-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896411098&partnerID=MN8TOARS. Salgado, C.L.; Sanchez, E.M.S.; Zavaglia, C.A.C.; Almeida, A.B.; Granja, P.L.. "Injectable biodegradable polycaprolactone-sebacic acid gels for bone tissue engineering". Tissue Engineering - Part A 18 1-2 (2012): 137-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855409671&partnerID=MN8TOARS. 10.1089/ten.tea.2011.0294 Bidarra, S.J.; Barrias, C.C.; Fonseca, K.B.; Barbosa, M.A.; Soares, R.A.; Granja, P.L.. "Injectable in situ crosslinkable RGD-modified alginate matrix for endothelial cells delivery". Biomaterials 32 31 (2011): 7897-7904. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051827430&partnerID=MN8TOARS. 10.1016/j.biomaterials.2011.07.013 Fonseca, K.B.; Bidarra, S.J.; Oliveira, M.J.; Granja, P.L.; Barrias, C.C.. "Molecularly designed alginate hydrogels susceptible to local proteolysis as three-dimensional cellular microenvironments". Acta Biomaterialia 7 4 (2011): 1674-1682. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952189303&partnerID=MN8TOARS. 10.1016/j.actbio.2010.12.029 Munarin, F.; Guerreiro, S.G.; Grellier, M.A.; Tanzi, M.C.; Barbosa, M.A.; Petrini, P.; Granja, P.L.. "Pectin-based injectable biomaterials for bone tissue engineering". Biomacromolecules 12 3 (2011): 568-577. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955409005&partnerID=MN8TOARS. 10.1021/bm101110x Bidarra, S.J.; Barrias, C.C.; Barbosa, M.A.; Soares, R.; Amédée, J.; Granja, P.L.. "Phenotypic and proliferative modulation of human mesenchymal stem cells via crosstalk with endothelial cells". Stem Cell Research 7 3 (2011): 186-197. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960458318&partnerID=MN8TOARS. 10.1016/j.scr.2011.05.006 Granja, P.L.. "Welcome to Biomatter.". Biomatter 1 1 (2011): 1-2. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896417444&partnerID=MN8TOARS. Lopes, J.L.; Machado, J.M.; Castanheira, L.; Granja, P.L.; Gama, F.M.; Dourado, F.; Gomes, J.R.. "Friction and wear behaviour of bacterial cellulose against articular cartilage". Wear 271 9-10 (2011): 2328-2333. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960657605&partnerID=MN8TOARS. 10.1016/j.wear.2010.12.042 Pandita, D.; Santos, J.L.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H.. "Gene delivery into mesenchymal stem cells: A biomimetic approach using rgd nanoclusters based on poly(amidoamine) dendrimers". Biomacromolecules 12 2 (2011): 472-481. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951658350&partnerID=MN8TOARS. 10.1021/bm1012647 Santos, J.L.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H.; Santos, José L.; et al. "Non-viral gene delivery to mesenchymal stem cells: Methods, strategies and application in bone tissue engineering and regeneration". Current Gene Therapy 11 1 (2011): 46-57. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951686783&partnerID=MN8TOARS. 10.2174/156652311794520102 Extremina, C.I.; Fonseca, A.F.d.; Granja, P.L.; Fonseca, A.P.. "Anti-adhesion and antiproliferative cellulose triacetate membrane for prevention of biomaterial-centred infections associated with Staphylococcus epidermidis". International Journal of Antimicrobial Agents 35 2 (2010): 164-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-72649093658&partnerID=MN8TOARS. 10.1016/j.ijantimicag.2009.09.017 Da Cunha, C.B.; Oliveira, C.; Wen, X.; Gomes, B.; Sousa, S.; Suriano, G.; Grellier, M.; et al. "De novo expression of CD44 variants in sporadic and hereditary gastric cancer". Laboratory Investigation 90 11 (2010): 1604-1614. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049336816&partnerID=MN8TOARS. 10.1038/labinvest.2010.155 Santos, J.L.; Oliveira, H.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H.. "Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells". Journal of Controlled Release 144 1 (2010): 55-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953239685&partnerID=MN8TOARS. 10.1016/j.jconrel.2010.01.034 Bidarra, S.J.; Barrias, C.C.; Barbosa, M.A.; Soares, R.; Granja, P.L.. "Immobilization of human mesenchymal stem cells within RGD-grafted alginate microspheres and assessment of their angiogenic potential". Biomacromolecules 11 8 (2010): 1956-1964. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955575798&partnerID=MN8TOARS. 10.1021/bm100264a Santos, J.L.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Balian, G.; Tomás, H.. "Receptor-mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells". Molecular Pharmaceutics 7 3 (2010): 763-774. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953253240&partnerID=MN8TOARS. 10.1021/mp9002877 Santos, J.L.; Oramas, E.; Pêgo, A.P.; Granja, P.L.; Tomás, H.. "Osteogenic differentiation of mesenchymal stem cells using PAMAM dendrimers as gene delivery vectors". Journal of Controlled Release 134 2 (2009): 141-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-60649096454&partnerID=MN8TOARS. 10.1016/j.jconrel.2008.11.007 Barrias, C.C.; Martins, M.C.L.; Almeida-Porada, G.; Barbosa, M.A.; Granja, P.L.. "The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers". Biomaterials 30 3 (2009): 307-316. http://www.scopus.com/inward/record.url?eid=2-s2.0-55249093830&partnerID=MN8TOARS. 10.1016/j.biomaterials.2008.09.048 Grellier, M.; Granja, P.L.; Fricain, J.-C.; Bidarra, S.J.; Renard, M.; Bareille, R.; Bourget, C.; Amédée, J.; Barbosa, M.A.. "The effect of the co-immobilization of human osteoprogenitors and endothelial cells within alginate microspheres on mineralization in a bone defect". Biomaterials 30 19 (2009): 3271-3278. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349213598&partnerID=MN8TOARS. 10.1016/j.biomaterials.2009.02.033 Grellier, M.; Bareille, R.; Bourget, C.; Ferreira Tojais, N.; Granja, P.; Barbosa, M.; Amédée, J.. "Cell cooperation between human osteoprogenitor and endothelial cells: Its function on bone tissue engineering". European Cells and Materials 14 SUPPL.1 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860864322&partnerID=MN8TOARS. Bidarra, S.J.; Barrias, C.C.; Barbosa, M.A.; Soares, R.; Granja, P.L.. "Immobilization of human mesenchymal stem cells". European Cells and Materials 14 SUPPL.1 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860862537&partnerID=MN8TOARS. Evangelista, M.B.; Hsiong, S.X.; Fernandes, R.; Sampaio, P.; Kong, H.-J.; Barrias, C.C.; Salema, R.; et al. "Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix". Biomaterials 28 25 (2007): 3644-3655. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249870130&partnerID=MN8TOARS. 10.1016/j.biomaterials.2007.04.028 Amaral, I.F.; Granja, P.L.; Melo, L.V.; Saramago, B.; Barbosa, M.A.. "Functionalization of chitosan membranes through phosphorylation: Atomic force microscopy, wettability, and cytotoxicity studies". Journal of Applied Polymer Science 102 1 (2006): 276-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749478403&partnerID=MN8TOARS. 10.1002/app.23737 Barrias, C.C.; Lamghari, M.; Granja, P.L.; Sá Miranda, M.C.; Barbosa, M.A.. "Biological evaluation of calcium alginate microspheres as a vehicle for the localized delivery of a therapeutic enzyme". Journal of Biomedical Materials Research - Part A 74 4 (2005): 545-552. http://www.scopus.com/inward/record.url?eid=2-s2.0-24044465170&partnerID=MN8TOARS. 10.1002/jbm.a.30348 Amaral, I.F.; Granja, P.L.; Barbosa, M.A.. "Chemical modification of chitosan by phosphorylation: An XPS, FT-IR and SEM study". Journal of Biomaterials Science, Polymer Edition 16 12 (2005): 1575-1593. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644875542&partnerID=MN8TOARS. 10.1163/156856205774576736 Ferreira, L.; Evangelista, M.B.; Martins, M.C.L.; Granja, P.L.; Esteves, J.L.; Barbosa, M.A.. "Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: Surface characterization and pull-out tests". Polymer 46 23 (2005): 9840-9850. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844540116&partnerID=MN8TOARS. 10.1016/j.polymer.2005.08.033 Granja, P.L.; De Jéso, B.; Bareille, R.; Rouais, F.; Baquey, C.; Barbosa, M.A.. "Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells". European Cells and Materials 10 (2005): 31-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-28444434484&partnerID=MN8TOARS. Barbosa, M.A.; Granja, P.L.; Barrias, C.C.; Amaral, I.F.. "Polysaccharides as scaffolds for bone regeneration". ITBM-RBM 26 3 (2005): 212-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-20744434609&partnerID=MN8TOARS. 10.1016/j.rbmret.2005.04.006 Barata, PD; Costa, AI; Granja, P; Prata, JV. "The synthesis of novel polymer-bound calix[4]arenes". REACTIVE & FUNCTIONAL POLYMERS (2004): https://www.authenticus.pt/P-000-DKH. 10.1016/j.reactfunctpolym.2004.04.005 Fricain, J.C.; Granja, P.L.; Barbosa, M.A.; De Jéso, B.; Barthe, N.; Baquey, C.; Jéso, B.D.; Bareille, R.; Rouais, F.. "Cellulose phosphates as biomaterials. In vivo biocompatibility studies". Biomaterials 23 4 (2002): 971-980. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037082737&partnerID=MN8TOARS. 10.1016/s0142-9612(01)00152-1 Fonseca, A.P.; Granja, P.L.; Nogueira, J.A.; Oliveira, D.R.; Barbosa, M.A.. "Staphylococcus epidermidis RP62A adhesion to chemically modified cellulose derivatives". Journal of Materials Science: Materials in Medicine 12 6 (2001): 543-548. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034951983&partnerID=MN8TOARS. 10.1023/a:1011227915575 Granja, P.L.; Pouysgu, L.; Ptraud, M.; De Jso, B.; Baquey, C.; Barbosa, M.A.. "Cellulose phosphates as biomaterials. I. Synthesis and characterization of highly phosphorylated cellulose gels". Journal of Applied Polymer Science 82 13 (2001): 3341-3353. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035923986&partnerID=MN8TOARS. 10.1002/app.2193 Granja, P.L.; Pouysgu, L.; Ptraud, M.; De Jso, B.; Baquey, C.; Barbosa, M.A.; Pouységu, L.; De Jéso, B.; Rouais, F.. "Cellulose phosphates as biomaterials. II. Surface chemical modification of regenerated cellulose hydrogels". Journal of Applied Polymer Science 82 13 (2001): 3354-3365. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035923980&partnerID=MN8TOARS. 10.1002/app.2194 Granja, P.L.; Ribeiro, C.C.; De Jéso, B.; Baquey, C.; Barbosa, M.A.. "Mineralization of regenerated cellulose hydrogels". Journal of Materials Science: Materials in Medicine 12 9 (2001): 785-791. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034771780&partnerID=MN8TOARS. 10.1023/a:1013960601330 Yunzhi, Y.; Jiemo, T.; Granja, P.L.. "Biomaterials network www.biomat.net is online". Chinese Journal of Biomedical Engineering 19 3 (2000): 359-360. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033789972&partnerID=MN8TOARS.
Capítulo de livro	Tavares, João; Vieira, Luís; Mosqueira, Diogo; Amaral, Isabel; Granja, Pedro; Pinto-do-Ó, Perpétua; Lima, R.; et al. "Química física da vida". Publindústria, Edições Técnicas, 2015.
Livro	Dos Santos, T.D.; Lourenço, B.N.; Coentro, J.; Granja, P.L.. Cell-based in vitro models for gastric permeability studies. 2015. 10.1016/B978-0-08-100094-6.00004-3 Granja, P.L.; Pereira, J.P.; Barbosa, M.A.. The Biomaterials Network (Biomat.net) as a Major Internet Resource for Biomaterials, Tissue Engineering and Biomineralization. 2008. 10.1002/9783527619443.ch68 Amaral, I.F.; Granja, P.L.; Barbosa, M.A.. In vitro Mineralisation of Chitosan Membranes Carrying Phosphate Functionalities. 2004. 10.4028/www.scientific.net/kem.254-256.577 Granja, P.L.; Silva, A.I.N.; Borges, J.P.; Barrias, C.C.; Amaral, I.F.. Preparation and Characterization of Injectable Chitosan-Hydroxyapatite Microspheres. 2004. 10.4028/WWW.SCIENTIFIC.NET/KEM.254-256.573
Resumo em conferência	Fonseca, KB; Granja, PL; Barrias, CC. "Physico-chemical and enzymatic properties of PVGLIG and PVGLIG-alginate hydrogels". 2012. Bidarra, S; Fonseca, K; Granja, PL; Barrias, CC. "Learning from the cell-matrix crosstalk to improve a cell delivery system based on RGD-modified alginate". 2012. Guerreiro, SG; Unger, RE; Sartoris, A; Martins, MJ; Barbosa, MA; Soares, R; Granja, PL; Kirkpatrick, CJ. "Crosstalk between fibroblasts and endothelial cells promotes angiogenesis in vitro: putative role of alkaline phosphatase". 2012. Guerreiro, S; Negrao, R; Oliveira, MJ; Barbosa, MA; Soares, R; Granja, PL. "Modulation of angiogenesis by fibroblasts in tissue regeneration". 2011. Santos, JL; Rodrigues, J; Pego, AP; Granja, PL; Tomas, H. "Novel conjugates of dendrimers and fatty acids for gene delivery applications". 2008. Sargo, S; Santos, JL; Rodrigues, J; Pego, AP; Granja, PL; Tomas, H. "New PAMAN dendrimers/alginate nanoparticles for gene delivery". 2008. Bidarra, SJ; Barrias, CC; Barbosa, MA; Soares, R; Granja, PL. "Upregulation of mesenchymal stem cells differentiation and proliferation in coculture with endothelial cells". 2008. Grellier, M; Bidarra, SJ; Bareille, R; Fricain, JC; Granja, PL; Barbosa, MA; Amedee, J. "Encapsulation of osteoprogenitor and endothelial cell co-cultures for bone tissue engineering application". 2008. 10.1016/j.bone.2007.12.022 Grellier, M; Bourge, C; Bareille, R; Granja, PL; Barbosa, MA; Amedee, J. "Cell cooperation between human osteoprogenitor cells and endothelial cells in tissue engineering". 2007. Extremina, CI; Granja, PL; da Fonseca, AF; Fonseca, AP. "Adhesion of Staphylococcus epidermidis to a modified cellulose triacetate membrane". 2007. 10.1016/s0924-8579(07)70458-2 Grellier, M; Bareille, R; Bourget, C; Ferreira Tojais, N; Granja, P; Barbosa, M; Amedee, J. "Cell cooperation between osteoprogenitor and endothelial cells for bone tissue engineering". 2007.
Tese / Dissertação	Granja, Vera Lúcia Ferreira. "Impacto das Soft Skills, no desenvolvimento das pessoas". Mestrado, 2019. http://hdl.handle.net/10400.26/31884. Lopes, Dalila Augusta Ferreira Mendes. "Molecular Imprinting as a tool for producing Molecularly Intelligent Scaffolds for Tissue Engineering". Mestrado, 2017. http://hdl.handle.net/10362/62922. Santos, Cláudio Miguel Dionísio dos. "Development of new biomaterials based on liquid crystalline phases of cellulose derivatives". Mestrado, 2010. http://hdl.handle.net/10362/5801. Extremina, Clara Isabel Teixeira. "Influence of antimicrobial agents on the adhesion of staphylococcus epidermidis to biomaterials". Mestrado, 2006. http://hdl.handle.net/10216/57705. Granja, Pedro Lopes. "Biomimetic natural materials for bone regeneration". Doutoramento, 2000. http://hdl.handle.net/10216/12704.

Outros

Outra produção

Skin models of cutaneous toxicity transdermal transport and wound repair. 2023. Inês Vilela de Sousa; Miguel Ferreira; Luís B. Bebiano; Sandra Simões; Ana Matos; Rúben F. Pereira; Pedro Granja. https://doi.org/10.1093/burnst/tkad014.
10.1093/burnst/tkad014
CD44v6 expression is a novel predictive marker of therapy response and poor prognosis in gastric cancer patients. 2018. Carla Pereira; Daniel Ferreira; Carolina Lemos; Diana Martins; Nuno Mendes; Daniela Almeida; Pedro Granja; et al. https://doi.org/10.1101/468934.
10.1101/468934

Atividades

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2023 - Atual	Gastric Patch – A Bioprinted 3D Engineered Patch for Gastric Ulcer Healing Orientador	PRODEB, FEUP (Doutoramento) i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2020 - Atual	Implantable electrospun nanofibers containing gold nanoparticles for local enhancement of radiotherapy in gastric tumors Orientador	PhD Program in Bomedical Engineering (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2014 - Atual	Cancer and Mechanobiology Orientador de Maria Manuela Brás	PhD Program in Bomedical Sciences (Doutoramento) i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2014 - Atual	Mechanobiology of cancer cells using atomic force microscopy Orientador	PhD Program in Bomedical Engineering (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2023 - 2026	Bioprinting of a vascularised cell-laden spinal cord graft: an anatomically relevant approach Orientador	PRODEB, FEUP (Doutoramento) i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2021 - 2021	Development of wound dressings based on a pectin and chitosan interpenetrating polymer network Orientador	Mestrado em Engenharia Biomédica (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2014 - 2021	A tissue engineering approach to fabricate a stomach-on-a-chip: A biomimetic device to decode the role of CD44V6 in cancer cells Orientador	BiotecHealth (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 - 2020	Seeking for new p53-activating agents: effective therapies for colorectal cancer Coorientador	BiotechHealth - International Doctoral Program in Molecular and Cellular Biotechnology Applied to Health Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2019	Functionalized nanoparticles loaded into an injectable cryogel for combined chemotherapy and cancer vaccination Coorientador	PhD Program in Bomedical Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2019	Colorectal cancer triple co-culture spheroid model to assess the biocompatibility and anticancer properties of polymeric nanoparticles Coorientador	PhD Program in Bomedical Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2019	Bioengineering 3D models to deconstruct the role of extracellular matrix microenvironment in gastric cancer Orientador	PhD Program in Biomedical Engineering (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2015 - 2018	Stomach Patch Orientador	MSc in Bioemdical Engineering (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2014 - 2018	Fab-conjugated PLGA nanoparticles effectively target cancer cells expressing human CD44v6 Coorientador	BiotechHealth (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2018	Hydrogel bioinks for bioprinting of bioengineered 3D constructs for skin tissue engineering Coorientador	PhD Program in Bomedical Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2018	Spheroids in vascularisation Coorientador	Industrial Biological Biomaterials Doctorate (IB2). EID – European Industrial Doctorates, Marie Curie Initial Training Networks (ITN) (Doutoramento) European Commission Seventh Framework Programme for Research and Technological Development Joint Technology Initiatives, Bélgica
2012 - 2017	Nanopharmaceuticals Coorientador	PhD Program in Bomedical Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2017	Hybrid electrospun PCL/gelatine nanostructures for skin regeneration Coorientador	PhD Program in Bomedical Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2017	Hybrid systems in tissue engineering Orientador	PhD Program in Biomedical Engineering (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2016 - 2016	Cellulose nanofibril-cell adhesive peptide conjugates for 3D printed skin tissue model Coorientador	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2016 - 2016	Molecularly imprinted intelligent scaffolds for tissue engineering applications Orientador	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2016 - 2016	The role of adsorbed proteins in the internalization of polymeric nanoparticles Orientador	MSc in Biochemistry (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2016 - 2016	Methacrylated hyaluronic acid and pectin cell-laden hydrogels for skin emulation Orientador	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2015 - 2015	Dynamically Adhesive Micropatterned Substrates for Studying and Controlling Cell Adhesion and Migration Coorientador	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2015 - 2015	Cell-laden micropatterns using self-assembled cell-ECM microtissues in soft pectin hydrogels Orientador	Biologia Celular e Molecular (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2014 - 2014	Complex cell-based model of intestine permeability Coorientador	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2014 - 2014	Establishment of a cellularized artificial model of the gastric wall Orientador	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2008 - 2014	Deconstruction CD44 - Engineering 3 D matrices to elucidate CD44 modulation in gastric malignancy Orientador	PhD Program in Biomedicine (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2013	3D Hybrid Scaffolds for Tissue Engineering Orientador	Engenharia Biomédica (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2013 - 2013	Pectin hydrogels for dermal substitutes Orientador	Bioengenharia (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal
2007 - 2013	Protease-sensitive hydrogels as 3D cellular microenvironments Orientador	PhD Program in Biomedical Engineering (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2008 - 2012	Modulation of angiogenesis by fibroblasts in tissue regeneration Orientador	PhD Program in Biomedical Engineering (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2008 - 2012	Matrix-driven formation of MSC-ECM microtissues on soft alginate hydrogels Coorientador	International Iberian Nanotechnology Laboratory, Portugal
2008 - 2011	Biofunctional chemically modified pectin for cell immobilization Coorientador	Politecnico di Milano, Itália
2005 - 2011	Exploring the crosstalk between mesenchymal stem cells and endothelial cells in bone tissue engineering Orientador	PhD Program in Biomedical Engineering (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2002 - 2008	Osteoprogenitors Differentiation Is Regulated by Cell-cell and Cell-extracellular Matrix Interactions: Implications for Bone Tissue Regeneration Orientador	Ciências de Engenharia (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal

Distinções

Título

2020	Fellow of Biomaterials Science and Engineering (FBSE)

Outra distinção

2016	Fundamental Research Prize (Joana Crisóstomo)
2016	Best Poster in Fundamental Research Award (Joana Crisóstomo)
2015	Best Poster Award (Daniel Carvalho, Guilherme Aresta, Miguel Ferreira and Raquel Costa-Almeida)
2015	Best Student Oral Presentation in Life Sciences (Miguel Ferreira)
2014	Prize for best poster (Sara C. Neves). Co-author
2014	Spin Your Thesis! 2014 (Antigravity project)
2014	Best PhD Thesis in Doctoral Program in Biomedicine 2013-2014 (Cristiana Branco da Cunha)
2013	2nd Prize on the Poster Competition (Raquel Costa-Almeida)
2012	Chair in Biomaterials, University of Havana, Cuba
2011	Prize for Best Poster (Cristina C. Barrias). Co-author
2011	YSF Excellence Award
2011	Prize for Best Poster (Ana Filipa Lourenço). Co-author
2010	Prize for Best Poster Award (F. Raquel Maia). Co-author
2009	Prize Best Poster of the Day (João L. Lopes); co-author
2009	Prize for Best Oral presentation (Susana Guerreiro); co-author
2009	Prize for Best Oral presentation (José Luís Santos); co-author
2007	Best oral presentation (M Grellier); co-author
2006	Jean Leray Award European Society for Biomaterials (ESB), França
2003	Special Oral presentation Award (Isabel F. Amaral); co-author