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Ana Fortuna is graduated in Pharmaceutical Sciences since 2007 and obtained the PhD degree in Pharmaceutical Sciences, specialty of Pharmacology, in 2011 at the Faculty of Pharmacy of University of Coimbra (FFUC). In 2022, Ana Fortuna acquired the European Certified Pharmacologist (EuCP) from the Federation of European Pharmacological Societies (EPHAR) e European Association for Clinical Pharmacology and Therapeutics (EACPT). She is an Assistant Professor at FFUC since 2011 in the area of Pharmacology and Pharmaceutical Care and an integrated researcher at the Coimbra Institute for Biomedical Imaging and Translational Research of University of Coimbra (CIBIT). Ana Fortuna is member of the INTERNATIONAL NASAL RESEARCH GROUP as well as of the Associated Laboratory for Intelligent Systems and the Collaborative Laboratory for Promoting Translation and Discovery of Medicines (Bioscale). Ana Fortuna is currently the supervisor of 3 PhD students and supervisor of 4 Master students in Applied Pharmacology. She has already successfully supervised 4 PhD students, 25 master's students and 36 integrated master's degree students. Ana Fortuna is the Coordinator of the Applied Pharmacology Master since 2018, a member of the Pedagogical Council of FFUC since 2016, of the Equivalence Committee since 2019, of the Scientific Council of Institute for Nuclear Sciences Applied to Health (ICNAS) and of the Scientific Committee for coordinating the Doctorate in Nursing study cycle. Participated in 102 evaluation juries, namely 14 PhD juries (3 as main arguer), 56 Master's juries (35 as main arguer), 1 Undergraduate, 20 Doctoral Program Seminars and 9 public competition juries for hiring PhD Researchers and Research Fellows. With a SCOPUS H-INDEX of 31 and 3150 total CITATIONS (Google Scholar: H-index 34 and 4394 citations), Ana Fortuna published 102 articles in international journals; among them, she was the first/last author or the corresponding author of 49 manuscripts. She is also the author of 3 INTERATIONAL PATENTS, 1 Editorial, 14 book chapters, and 134 oral/poster communications at scientific national/international meetings. Ana Fortuna was the principal investigator of the projects CENTRO-01-0145-FEDER-030752 (funded by FCT, 2018-2022) and SustaINsafety (funded by INOVC+, 2022-2023), both with the objective of developing and validating intranasal administration systems for delivery of drugs for the brain. She additionally integrates 1 European Project and 3 national projects. She has also integrated other 7 national projects, and coordinated/integrated 7 projects financed by the pharmaceutical industry, and 3 strategic institutional projects as an Integrated Member of CIBIT. Throughout academic and scientific career, Ana Fortuna was awarded 14 SCIENTIFIC AWARDS, integrating, in 2022 and 2023, the World's Top 2% Scientist, according to a study by Stanford University (USA) and the Elsevier publishing group. Ana Fortuna has been invited to participate in relevant activities, involving the public and private sectors, highlighting the provision of services to public and private entities in conjunction with the University of Coimbra through the COORDINATION OF THE TECHNOLOGICAL PLATFORM OF THE UNIVERSITY OF COIMBRA - Unit of Pharmacokinetics and Bioanalysis. Ana Fortuna also leads the PkXplorer project, integrated at the University of Coimbra and in the Virtual Incubator at Instituto Pedro Nunes (IPN). The main research areas of investigation include: interaction between drugs and efflux transporters, in vitro/in vivo pharmacokinetics and pharmacodynamics of new drugs for depression, epilepsy and Alzheimer´s disease, as well as development/validation of bioanalytical techniques that are employed on drug pharmacokinetics monitoring.
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Identification

Personal identification

Full name
Ana Fortuna

Citation names

  • Fortuna, Ana

Author identifiers

Ciência ID
E510-8BF0-1756
ORCID iD
0000-0001-6981-6639
Google Scholar ID
Ana Fortuna
Scopus Author Id
36941957200

Email addresses

  • afortuna@ff.uc.pt (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2023/10 - 2024/04
Ongoing
 Prepare for teaching in digital and distance environments (Outros)
Universidade de Coimbra, Portugal
2023/11 - 2023/12
Concluded
 Teaching and Assessment Methodologies in an Active Learning Context (Outros)
Universidade de Coimbra, Portugal
2023/11 - 2023/11
Concluded
 Pharmacist Intervention Course for Depression (Outros)
Ordem dos Farmaceuticos, Portugal
2023/05/22 - 2023/07/30
Concluded
 Implementation of pharmacokinetic monitoring in pharmaceutical services (Outros)
Associação Portuguesa de Farmacêuticos Hospitalares (APFH), Portugal
2023/04/11 - 2023/06/11
Concluded
 TEACHER DIGITAL COMPETENCE: pedagogical assessment (Outros)
Universidade de Aveiro, Portugal
2023/06 - 2023/06
Concluded
 Training session on Pharmacokinetic monitoring: Tyrosine kinase inhibitors (Outros)
Associação Portuguesa de Farmacêuticos Hospitalares (APFH), Portugal
2023/02/08 - 2023/04/05
Concluded
 Seed Tech Transfer (Outros)
Universidade de Coimbra, Portugal
2023/03/20 - 2023/03/24
Concluded
 Modeling and Simulations Using MonolixSuite¿: Pharmacometrics Spring School (Outros)
Simulations Plus Inc, United States
2023/01/09 - 2023/01/13
Concluded
 2nd Academic Teaching Excellence Training for Academic Staff (Outros)
European Network On Teaching Excellence (E-NOTE), Denmark
2022/10/04 - 2022/10/26
Concluded
 INEO START: Transforming technologies and ideas into business (Outros)
Instituto Pedro Nunes, Portugal
2022/10/04 - 2022/10/26
Concluded
 Clinical Pharmacology Course (Outros)
International Union of Basic and Clinical Pharmacology, United States
2022/10/17 - 2022/10/21
Concluded
 DARTER Training School Introduction to Nucleic Acid Therapy (Outros)
European Cooperation in Science and Technology, Belgium
2022/07/19 - 2022/07/19
Concluded
 Doctoral Supervision Best Practices Course (Outros)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2022/05/04 - 2022/05/04
Concluded
 Training session on Pharmacokinetic monitoring: Biologics (Outros)
Associação Portuguesa de Farmacêuticos Hospitalares (APFH), Portugal
2022/04/29 - 2022/04/29
Concluded
 Training session on Pharmacokinetic monitoring: immunosupressant drugs (Outros)
Associação Portuguesa de Farmacêuticos Hospitalares (APFH), Portugal
2020/10/23 - 2020/10/30
Concluded
 Planning, production and use of digital audiovisual resources in a pedagogical context (Outros)
Universidade de Coimbra, Portugal
2020/09/14 - 2020/09/14
Concluded
 Workshop Project Based Learning (PBL) no contexto do Ensino Superior: do conceito à prática (Outros)
Universidade de Coimbra, Portugal
2020/09/08 - 2020/09/08
Concluded
 Active Methodologies: Flipped classroom and Peer instruction (Outros)
Universidade de Coimbra, Portugal
2020/09 - 2020/09
Concluded
 Workshop Planificação, desenvolvimento e implementação de cenários de aprendizagem em ambientes mistos (Outros)
Universidade de Coimbra, Portugal
2017/05 - 2017/05
Concluded
 Curso de Monitorizácion de Fármacos en la Pratica Clínica (Pós-Graduação)
Universidad de Salamanca Facultad de Farmacia, Spain
2015 - 2015
Concluded
 Tissue Training Course Beyond the Microscope, culturing III Cell Culture and Life (67 h) (Pós-Graduação)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011/10/04
Concluded
 PhD, in Pharmacy, Especiallity of Pharmacology (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Análise farmacométrica de derivados da carbamazepina: avaliação in vitro, in vivo e in silico das suas propriedades farmacológicas" (THESIS/DISSERTATION)
 Aprovado por unanimidade com distinção e louvor
2009 - 2009
Concluded
 Biostatistics: Introductory Statistics and Research Methods (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009 - 2009
Concluded
 VIII Curso de Experimentação Animal (90h) - Curso acreditado pela Direcção Geral de Veterinária e que corresponde ao nível C da Federation of European Laboratory Animal Science Associations (FELASA) (Outros)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2007/03/20 - 2007/06/03
Concluded
 X Curso de Determinación de fármacos por HPLC en muestras biológicas (50h) (Pós-Graduação)
Universidad de Salamanca Facultad de Farmacia, Spain
2006/06
Concluded
 PharmD: Licenciatura em Ciencias Farmacêuticas (Pré-bolonha) (Licenciatura)
Universidade de Coimbra Faculdade de Farmácia, Portugal
 17
Affiliation

Science

Category
Host institution 		Employer
2018 - Current Researcher (Research) Coimbra Institute for Biomedical Imaging and Translational Research, Portugal
2009 - 2018 Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2014/09/01 - Current Assistant Professor (University Teacher) Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal
2011/10/06 - 2014/08/31 Invited Assistant Professor (University Teacher) Universidade de Coimbra Faculdade de Farmácia, Portugal

Positions / Appointments

Category
Host institution 		Employer
2021 - Current Member of Scientific Council Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
2021 - Current Comissão Científica para coordenação do ciclo de estudos de Doutoramento em Enfermagem Universidade de Coimbra, Portugal
2019 - Current Member of Equivalence Commission Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 - Current Coordinator of Applied Pharmacology Master Universidade de Coimbra Faculdade de Farmácia, Portugal
2016 - Current Member of the Pedagogic Council Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2021 - Current Strive against Alzheimer´s disease through the modulation of depressive state and the use of cannabinoids
2021.06135.BD
Supervisor
Fundação para a Ciência e a Tecnologia
2021 - Current Evaluation of intranasal delivery of cannabinoids and their potential for the treatment of epilepsy
2021.06125.BD
Supervisor
Fundação para a Ciência e a Tecnologia
2020 - 2024/10 Targeting the brain renin-angiotensin system by nose-to-brain delivery for prevention and treatment of Alzheimer's disease
2020.04442.BD
Supervisor
Fundação para a Ciência e a Tecnologia
2020 - 2024/06 Chronopharmacokinetics and chronopharmacodynamics of intranasal antidepressant drugs
PD/BDE/150685/2020
Supervisor
Fundação para a Ciência e a Tecnologia
2019 - 2024/02 Biohybrid Nanosystems for Drug and Nucleic Acid co-Delivery in Glioblastoma
SFRH/BD/149138/2019
Supervisor
Fundação para a Ciência e a Tecnologia
2019 - 2024 Amorphous solid dispersions for nasal delivery: bridging particle engineering with in vitro and in vivo performance
PD/BDE/150298/2019
Supervisor
Fundação para a Ciência e a Tecnologia
2007/01 - 2010/12 Pharmacometric analysis of analogues of carbamazepine: in vitro, in vivo and in silico evaluation of their pharmacological properties (SFRH/BD/31390/2006)
SFRH/BD/31390/2006
 Fundação para a Ciência e Tecnologia
Concluded

Other

Designation Funders
2023/03 - Current Interação calcitonina-receptor promovida por nanopartículas guiadas por péptidos como uma nova abordagem para tratamento de glioblastoma
2022.06174.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
2023/03 - Current O triptofano pré-natal como interveniente principal na disfunção do eixo intestino-cérebro: uma abordagem pré-clínica no transtorno do espectro do autismo
2022.01066.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2023 - Current Modulação epigenética da integridade da barreira hematoencefálica para a prevenção da epileptogénese
2022.03133.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
2022 - Current Bioloop - Portugal como impulsionador da Economia Circular nos bioplásticos
FEDER-072278
Researcher
2022/11 - 2023/07 SustaINsafety - Proof of concept study for the use of intranasal administration as an innovative strategy for the sustained and safe delivery of drugs with high binding to plasma proteins
SustaINsafety
Principal investigator
Concluded
2022 - 2023 NanoLIP - Nanopartículas lipídicas sólidas para o tratamento de tumores cerebrais (01/SAICT/2021 - SAICT-Projeto: 181224 )
01/SAICT/2021 - SAICT
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2022 - 2023 MitoBOOSTV2.0: Prova de Conceito para o Uso de Polifenóis Dirigidos à Mitocôndria para Tratar a Doença do Fígado Gordo Não-Alcoólico
MitoBoost.v2
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2022/07 N2BD - Development of a Novel Nose-to-Brain multifunctional nanoplatform for the treatment of Depression and prevention of pharmacoresistance development (ref. CENTRO-01-0145-FEDER-030752)
CENTRO-01-0145-FEDER-030752
Principal investigator
Universidade de Coimbra Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2022/07 4Epilepsy - Promoting the quality-of-life of epileptic patients through personalized medicine (POCI-01-0145-FEDER-030478)
POCI-01-0145-FEDER-030478
Researcher
Universidade de Coimbra Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
2018 - 2021 Skin allergens: molecules with an improbable therapeutic application for Alzheimer’s disease (POCI-01-0145-FEDER-029369)
POCI-01-0145-FEDER-029369
Researcher
CNC.IBILI, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2016 - 2019 Dual nanostructured lipid carriers as a multifunctional platform for brain tumor therapy ( PTDC/CTM-NAN/2658/2014; POCI-01-0145-FEDER016648)
PTDC/CTM-NAN/2658/2014
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2016 - 2019 IMPUCT 2 - Desenvolvimento Tecnológico de Implantes Poliméricos para Libertação Prolongada de Fármacos 2 (POCI-01-0247-FEDER-017650)
POCI-01-0247-FEDER-017650
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Mariana Neves; Miranda, Margarida; Fortuna, Ana; João José Sousa; Carla Sofia Pinheiro Vitorino. "Physiologically-Based Pharmacokinetic Modeling to Support the Determination of Drug Product Bioequivalence". In Time-Proof Perspectives on Bioequivalence. 2023.
    Published
  2. Bicker, Joana; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Understanding brain delivery". In Nanoparticles for Brain Drug Delivery. 2020.
    Published
  3. Serralheiro, Ana; Falcão, Amílcar; Alves, Gilberto; Fortuna, Ana. "Novel Routes to Accessing the Brain: Intranasal Administration". In Nanoparticles for Brain Drug Delivery. 2020.
    Published
  4. Basso, João; Sereno, José Vitor Oliveira; Fortuna, Ana; Castelo-Branco, Miguel; Vitorino, Carla. "Establishing xenograft glioblastoma models for use in preclinical development". In Nanotherapy for Brain Tumor Drug Delivery, Neuromethods Book Series. Springer Nature, 2020.
    Published
  5. Basso, João; Mendes, Maria; Fortuna, Ana; Vitorino, Rui; Sousa, João; Pais, Alberto; Vitorino, Carla. "Chapter 15: Nanotechnological approaches in cancer: the role of Celecoxib and Disulfiram.". In Drug Repurposing in Cancer Therapy: Approaches and Applications. Elsevier, 2020.
    Published
  6. Fortuna, Ana. "Establishing Orthotopic Xenograft Glioblastoma Models for Use in Preclinical Development". In Nanotherapy for Brain Tumor Drug Delivery. Springer Nature, 2020.
    Published
  7. Basso, João; Mendes, Maria; Fortuna, Ana; Vitorino, Rui; Sousa, João; Pais, Alberto; Vitorino, Carla. "Nanotechnological approaches in cancer". In Drug Repurposing in Cancer Therapy, 353-393. Elsevier, 2020.
    10.1016/b978-0-12-819668-7.00014-2
  8. Vieira, Raquel; Fortuna, Ana C.; Silva, Amélia M.; Souto, Selma B.; Souto, Eliana B.. "Mechanism of Action and Toxicological Profile of Essential Oils in Foodstuff". In Advances in Processing Technologies for Bio-based Nanosystems in Food, 211-230. CRC Press, 2019.
    10.1201/9781315177328-10
  9. Rodrigues, Marcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Microextraction Techniques in LC-MS Bioanalysis". In Sample Preparation in LC-MS Bioanalysis, 98-116. 2018.
    Published
  10. Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "2.1 Pharmacokinetics and Bioanalysis to Improve Drug Development". In Biomedical Chemistry, 62-118. De Gruyter Open, 2015.
    Published • 10.1515/9783110468755-003
  11. Fortuna, A.; Alves, G.; Falcão, A.. "Pharmacokinetics and bioanalysis to improve drug development". 2015.
  12. Fortuna, A.; Alves, G.; Falcão, A.; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "The pharmacology of simvastatin: From the mechanism of action to new therapeutic applications". In Simvastatin Delivery ¿ Challenges and opportunities., 21-60. Nova Sciences Publishers, Inc., 2015.
  13. Serralheiro, Ana; Alves, Gilberto; Sousa, Joana; Fortuna, Ana; Falcão, Amílcar; Serralheiro, A.; Alves, G.; et al. "Nose as a Route for Drug Delivery". In Nasal Physiology and Pathophysiology of Nasal Disorders, 191-215. Springer Berlin Heidelberg, 2013.
    Published • 10.1007/978-3-642-37250-6_15
  14. Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar; Alves, G.; Fortuna, A.; Falcão, A.. "Bioanalysis in drug discovery and development: focus on pharmacokinetic studies". In Biomedical chromatography, ---. Nova Science Publishers, Inc, 2010.
    Published
Conference abstract
  1. Meirinho, Sara; Gomes, Maria; Catarina Ferreira; Caetano Oliveira, Rui; SANTOS, ADRIANA O.; Fortuna, Ana; Amílcar Falcão; Alves, Gilberto. "Nose-to-brain delivery of perampanel using a non-toxic self-microemulsion drug delivery system.". Paper presented in 52ª Reunião da Sociedade Portuguesa de Farmacologia, 40ª Reunião de Farmacologia Clínica e 21ª Reunião de Toxicologia, Porto, 2022.
  2. Patrícia Henriques; Bicker, Joana; Doktorovova, Slavomira; Fortuna, Ana. "Nasal-PAMPA: a novel in vitro tool for prediction of intranasal drug permeability". Paper presented in Drug Delivery to the Lungs, 2022.
    Published
  3. Meirinho, Sara; Rodrigues, Márcio; SANTOS, ADRIANA O.; Fortuna, Ana; Amílcar Falcão; Alves, Gilberto. "Nose-to-brain delivery of perampanel: a promising therapeutic approach for epilepsy". Paper presented in 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of the Clinical Pharmacology and 20th Meeting of the Toxicology, Lisboa, 2021.
  4. Vitorino, Carla; Silva, Soraia; Bicker, Joana; Carona, Andreia; Falcão, Amílcar; Fortuna, Ana. "Designing Lipid Nanoparticles for Intranasal Delivery of Antidepressants.". Paper presented in Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2020.
    Published
  5. Meirinho, Sara; Fortuna, Ana; Rodrigues, Márcio; Falcão, Amílcar; Alves, Gilberto. "Development and validation of the first HPLC-DAD method for rufinamide quantification in mouse plasma and tissues with focus on future pharmacokinetic studies.". Paper presented in XLIX Reunião da Sociedade Portuguesa de Farmacologia, Porto, 2019.
  6. Meirinho, Sara; Fortuna, Ana; Rodrigues, Márcio; Falcão, Amílcar; Alves, Gilberto. "Novel bioanalytical method for the quantification of rufinamide in mouse plasma and tissues using HPLC-DAD: a tool to perform pharmacokinetic studies.". Paper presented in XIII Annual CICS-UBI Symposium 2018, Covilhã, 2018.
  7. Magalhães, Paulo; Alves, Gilberto; Llerena, Adrián; Fortuna, Ana; Falcão, Amílcar. "Genetic characterization of the CYP2C9, CYP2C19, CYPD6 isoenzymes and P-glycoprotein in portuguese patients with depression". Paper presented in 47th European Symposium on Clinical Pharmacy, Belfast, Northern Ireland, 2018.
    10.1007/s11096-018-0759-9
Conference paper
  1. João Basso; Ana Fortuna; Rui Vitorino; Carla Vitorino. "Precision Meets Affordability: A Highly Sensitive HPLC-FLD Technique for Accurate Pitavastatin Quantification in Human Plasma". 2023.
    10.3390/CSAC2023-14931
  2. Basso, João; Sousa, João; Vitorino, Rui; Fortuna, Ana; Vitorino, Carla. "Otimização da Entrega de Fármacos com Transportadores Lipídicos Nanoestruturados no Glioblastoma". Paper presented in X Congresso Iberoamericano em Ciências Farmacêuticas, 2023.
  3. Gonçalves, Joana; Silva, Soraia; Carla Sofia Pinheiro Vitorino; Alves, Gilberto; Fortuna, Ana. "How does the device determine nose-to-brain drug delivery to mice?". Paper presented in Drug Delivery to the Lungs (DDL 2019), 2019.
  4. David, Dezso; Freixo, João P.; Marques Barbara; Carvalho, Inês; Nataliya Tkachenko; Natalia Oliva-Teles; Marques, Mariana; et al. "Early results of next-gen cytogenetics implementation in Portugal". Paper presented in European Human Genetics Conference 2016, Barcelona, 2016.
  5. Bicker, Joana; Alves, Gilberto; Cavaleiro, Carlos; Fortuna, Ana; Amílcar Falcão. "Identification of P-glycoprotein inhibitors in Caco 2 cells: An in vitro screening methodology". Paper presented in 9th World Meeting on Pharmaceutics, 2014.
    Accepted
  6. Serralheiro, Ana ; Alves, Gilberto; Fortuna, Ana; Amílcar Falcão. "Direct nose-to-brain delivery of carbamazepine after intranasal administration to mice.". Paper presented in 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2014.
Conference poster
  1. Lapo Pais, Mariana; Sereno, José Vitor Oliveira; Tomé, Vanessa A.; Fonseca, Carla; Martins, João; Fortuna, Ana; Abrunhosa, Antero; Castelo-Branco, Miguel; Gonçalves, Joana. "Possible relationship between tryptophan metabolism, serotonergic function and E/I neurotransmitters in Tuberous Sclerosis Complex 2". Paper presented in EMIM 2024, 2024.
  2. Basso, João; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "Enhancing glioblastoma therapy through lipid nanoparticle-mediated drug and gene co-delivery". Paper presented in XVth SPLC-CRS Conference on Controlled Drug Delivery: "New Horizons in Drug Delivery", 2024.
  3. Gouveia, Filipa; Fonseca, Carla; Bicker, Joana; Camins, Antoni; Cruz, Maria Teresa; Ettcheto, Miren; Fortuna Ana. "Intranasal Administration of Irbesartan as a New Strategy for Addressing Neurodegeneration in a Neuroinflammation Mice Model: Pharmacokinetic and Efficacy Evaluation". Paper presented in Congresso do Núcleo de Estudantes de Farmácia da Associação Académica de Coimbra, 2024.
  4. Lapo Pais, Mariana; Sereno, José Vitor Oliveira; Tomé, Vanessa A.; Fonseca, Carla; Martins, João; Fortuna, Ana; Abrunhosa, Antero; Castelo-Branco, Miguel; Gonçalves, Joana. "Negative correlation between cortical tryptophan metabolism and E/I balance in a genetic mouse model of autism spectrum disorders". Paper presented in 2nd CIBIT Meeting, 2023.
  5. Silva, Rui; Colom, Helena; Almeida, Anabela; Bicker, Joana; Carona, Andreia; Silva, Ana; Sales, Francisco; et al. "Development of a Pharmacokinetic Model for Bayesian Individualization of Oral Levetiracetam in Refractory Epileptic Patients". Paper presented in 2nd Annual Meeting of CIBIT, 2023.
  6. Fonseca, Carla; Lapo Pais, Mariana; Bicker, Joana; Carona, Andreia; Ferreira, Ricardo; Barbosa, Rui M.; Camins, Antoni; Ettcheto, Miren; Fortuna, Ana. "A new bioanalytical tool for neurotransmitter monitoring in central nervous system diseases". Paper presented in 2nd Annual Meeting of CIBIT, 2023.
  7. Basso, João; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "Unveiling the molecular mechanisms of pitavastatin induced glioblastoma death using proteomics". Paper presented in PharmahDay 2023 | Annual Meeting of PhD Students in Pharmaceutical Sciences, 2023.
  8. Carona, Andreia; Bicker, Joana; Cunha, Susana; Filipa Gouveia; Fonseca, Carla; Amílcar Falcão; Fortuna, Ana. "HPLC DAD technique for the quantification of cannabinoids in human plasma and mouse matrices". Paper presented in PharmahDay 2023 | Annual Meeting of PhD Students in Pharmaceutical Sciences, 2023.
  9. Silva, Soraia; Fialho, Sara; Fortuna, Ana. Corresponding author: Fortuna, Ana. "Gender Differences During Unpredictable Chronic Mild Stress (UCMS) And Paroxetine Intranasal Administration To Mice". Paper presented in 36th ECNP Congress, 2023.
  10. Gouveia, Filipa; Bicker, Joana; Carona, Andreia; Ettcheto, Miren; Cruz, Maria Teresa; Fortuna, Ana. "Ultra High Performance Liquid Chromatography Technique to support Pharmacokinetic Monitoring of Losartan, Irbesartan and Valsartan". Paper presented in X Congresso Iberoamericano de Ciências Farmacêuticas, 2023.
  11. Basso, João; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "Decoding the molecular mechanisms of pitavastatin induced glioblastoma death through proteomics". Paper presented in ESN-ISN Neurochemistry School 2023, 2023.
  12. Gouveia, Filipa; Fonseca, Carla; Ana Silva; Antoni Camins; Maria Tereza Cruz; Ettcheto, Miren; Fortuna, Ana. "Angiotensin Receptor Blockers as an Alternative Strategy for Addressing Neurodegeneration in a LPS Mice Model". Paper presented in Alzheimer’s Association International Congress, 2023.
  13. Basso, João; Pais, Alberto; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "Achieving accurate measurements without breaking the bank: A highly sensitive technique for pitavastatin quantification in human plasma". Paper presented in XXVIII Encontro nacional da Sociedade Portuguesa de Química, 2023.
  14. Carona, Andreia; Bicker, Joana; Fonseca, Carla; Falcão, Amílcar; Fortuna, Ana. "High Performance Liquid Chromatography Technique for the Quantification of Cannabigerol, Cannabidiol, Cannabinol and Cannabichromene in human plasma and mice matrix". Paper presented in International Scientific Congress - Clearing the smoke¿.: the importance of the endocannabinoid system in health and disease, 2023.
  15. Basso, João; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "Drug and Gene Delivery in Glioblastoma: Friends or Foes?, Delivery of RNA Therapeutics". Paper presented in Delivery of RNA Therapeutics, Final DARTER Meeting, 2023.
  16. Basso, João; Pais, Alberto; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "The quest for better treatments: a novel drug delivery approach to glioblastoma". Paper presented in IX Iberian Meeting on Colloids and Interfaces, 2022.
  17. R. Ferreira, Nuno; Fialho, Sara; Fortuna, Ana; Vitorino, Carla. "Optimizing nanostructured lipid carriers for the intra nasal administration of paroxetine and escitalopram in the treatment of depression". Paper presented in 1st Advances in Polymeric Micelles for Therapeutic Applications, Coimbra, Portugal, 2022.
  18. "Nasal-PAMPA: a novel in vitro tool for the prediction of intranasal drug permeability and its application to formulations of a poorly-soluble drug". Paper presented in PBP World Meeting 2022, 2022.
  19. Basso, João; Mendes, Maria; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "Taking the most out of lipids: A systematic design of lipid-based nanoparticles". Paper presented in 1st Advances in Polymeric Micelles for Therapeutic Applications, Coimbra, Portugal, 2022.
  20. Gouveia, Filipa; Camins, Antoni; Ettcheto, Miren; Maria Teresa Rosete; Fortuna, Ana. "Renin-angiotensin system acting drugs: a possible role in Alzheimer’s disease". Paper presented in International Multi-Brain Barcelona Congress - Healthy, Pathological and Artificial Brain, 2022.
  21. Fonseca, Carla; Ettcheto, Miren; Camins, Antoni; Ferreira Nuno; Bicker, Joana; Barbosa, Rui; Fortuna, Ana. "New HPLC technology for monitoring neurotransmitters in the brain: a pre-clinical approach for neurological disorders". Paper presented in ternational Multi-Brain Barcelona Congress - Healthy, Pathological and Artificial Brain, 2022.
  22. "Therapeutic drug monitoring of clozapine on patients with refractory schizophrenia". Paper presented in ESCP 2021 Virtual Symposium- Clinical pharmacy, 2021.
  23. Santos, Joana; António, Natália; Gonçalves, Lino; Rocha, Marília João; Fortuna, Ana. "DIRECT ORAL ANTICOAGULANTS (DOACS) USE IN PATIENTS WITH CARDIAC IMPLANTABLE DEVICES AND NON-VALVULAR ATRIAL FIBRILLATION: IMPACT OF OFF-LABEL DOSE USE IN SAFETY AND EFFICACY OUTCOMES". Paper presented in ESCP 2021 Symposium: Clinical pharmacy, working collaboratively in mental health care, 2021.
  24. "The impact of smoking habits and comedicated drugs on clozapine/norclozapine ratios". Paper presented in 4º Encontro SPFCS, 2021.
  25. Patricia Henriques; João Marques; Margarida Miranda; Fortuna, Ana; Maria Braga; Slavomíra Doktorovová; Patrícia Henriques; João Henriques. "Amorphous Solid Dispersions for Nasal Delivery: Development, Characterization and Performance Studies". Paper presented in RDD 2021, 2021.
  26. Patrícia Henriques; João Marques; Margarida Miranda; Fortuna, Ana; Patrícia D. Nunes; Slavomíra Doktorovová. "In vitro release methodologies for nasal powder testing". Paper presented in PBP World Meeting, 2021.
  27. Andreia Carona; Joana Bicker; Rui Silva; Ana Silva; Isabel Santana; Francisco Sales; Amílcar Falcão; Fortuna, Ana. "Quantificação de fármacos antiepiléticos em saliva humana como uma nova ferramenta de monitorização da terapêutica". Paper presented in  33º Encontro Nacional de Epileptologia, 2021.
  28. Carona, Andreia; Bicker, Joana; Silva, Rui; Silva, Ana; Santana, Isabel; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Quantification of antiepileptic drugs in human saliva as a new tool of therapeutic monitoring.". Paper presented in 33º Nacional Meeting of Epileptology, 2021.
  29. Patrícia Henriques; João Marques; Maria Paisana; Fortuna, Ana; Slavomíra Doktorovová. "Benchmarking of particle engineering technologies for nasal powder manufacture". Paper presented in DDL 2020, 2020.
  30. Henriques, Patrícia; Marques, João; Noriega Fernandes, Beatriz; Fortuna, Ana; Braga, Maria. "Nasal powder delivery: a step towards a biorelevant dissolution system". Paper presented in Drug Delivery to the Lungs (DDL2019), 2019.
  31. Gonçalves, Joana; Silva, Soraia; Vitorino, Carla; Alves, Gilberto; Fortuna, Ana. "How does the device determine nose-to-brain drug delivery to mice?". Paper presented in Drug Delivery to the Lungs (DDL 2019), 2019.
  32. Silva, Soraia; Vitorino, Carla; Gonçalves, Joana; Carona, Andreia; Bicker, Joana; Falcão, Amilcar; Fortuna, Ana; Falcão, Amílcar. "Application of in vitro nasal model for antidepressant drug permeation studies". Paper presented in 1st Annual Meeting in Pharmaceutical Sciences, 2019.
  33. Silva, Rui; Almeida, Anabela; Bicker, Joana; Carona, Andreia; Sales, Francisco; Bento, Conceição; Falcão, Amílcar; Fortuna, Ana. "Pharmacokinetic data model on assessing adherence to levetiracetam". Paper presented in 48th Symposium of European Society of Clinical Pharmacy (ESCP 2019), 2019.
  34. Santos, Joana; Mendes, Ana Rita; Silva, Rui; António, Natália; Rocha, Marília; Fortuna, Ana. "Direct oral anticoagulants (DOACs) use in patients with cardiac implantable devices and non-valvular atrial fibrillation: the complexity of dose adjustments". Paper presented in 48th Symposium of European Society of Clinical Pharmacy (ESCP 2019), 2019.
  35. Gonçalves, Joana; Silva, Soraia; Bicker, Joana; Alves, Gilberto; Falcão, Amílcar; Fortuna, Ana. "Nose-to-brain delivery of levetiracetam: preclinical evidence". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  36. Silva, Rui; Almeida, Anabela; Bicker, Joana; Gonçalves, Joana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Therapeutic drug monitoring of levetiracetam: Pharmacokinetic characterization and compliance assessment of epileptic patients". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  37. Santos, Joana; Mendes, Ana Rita; Rocha, Marília; António, Natália; Fortuna, Ana. "Direct oral anticoagulants (DOACs) adjustment in patients with cardiac implantable devices and non-valvular atrial fibrillation, foccusing on renal adjustment: a single-centre retrospective study". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  38. Alves, Gilberto; Meirinho, Sara; Campos, Gonçalo; Fortuna, Ana; Falcão, Amílcar; Rodrigues, Márcio. "Development and validation of the first HPLC method for quantification of perampanel and stiripentol in mouse matrices using an innovator salting-out assisted liquid-liquid extraction procedure optimized by a design of experiments approach". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI 2019), 2019.
  39. Santos, Joana; António, Natália; Fortuna, Ana; Rocha, Marília; Mendes, Ana Rita. "Direct Oral Anticoagulants adjustment in patients with cardiac implantable devices and non-valvular Atrial Fibrillation: A single-centre retrospective study". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), 2019.
  40. Silva, Luis; Almeida, Anabela; Gonçalves, Joana; Silva, Ana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Caracterização do perfil farmacocinético do levetiracetam em doentes Portugueses com epilepsia". Paper presented in 31º Encontro Nacional de Epileptologia, 2019.
  41. Andrade, Ana; Rocha, Marília; Falcão, Amílcar; Fortuna, Ana. "Application of pharmacokinetic monitoring of amikacin in its pharmacological effects". Paper presented in 47th ESPC Symposium on Clinical Pharmacy, 2018.
  42. Morais, T.; Fortuna, A.; Fernandes, J.P.; Girola, N.; Falcão, A.; Lago, J.. "ADME-T and pharmacokinetic parameters of antitrypanosomal/antitumoral analogues of licarin A". Paper presented in 41ª Reunião Anual da Sociedade Brasileira de Química, 2018.
  43. Gonçalves, Joana; Paulino, Jamal; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Desenvolvimento e validação de uma nova metodologia de quantificação simultânea da lacosamida, levetiracetam e zonisamida em plasma de doentes epilépticos". Paper presented in 30º Encontro Nacional de Epileptologia, 2018.
  44. Gonçalves, Joana; Paulino, Jamal; Sales, Francisco; Falcao, Amilcar; Fortuna, Ana. "Desenvolvimento e validação de um método para quantificação simultânea de lacosamida, levetiracetam e zonisamida no plasma de doentes epiléticos". Paper presented in Encontro Nacional de Epileptologia, 2018.
  45. Gonçalves, Joana; Paulino, J.; Gouveia, Filipa; Silva, Ana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Monitoring lacosamide, levetiracetam, zonisamide in plasma of epileptic patients: personalizing the pharmacotherapy of levetiracetam". Paper presented in 47th ESPC Symposium on Clinical Pharmacy, 2018.
  46. Tinoco, Maria; Rocha, Marília; Sousa, Ana; Falcão, Amílcar; Fortuna, Ana. "Evaluation of the pharmacokinetics of amikacin in neutropenic cancer patients: influence of cancer pathology and chemotherapy". Paper presented in 47th ESPC Symposium on Clinical Pharmacy, 2018.
  47. Magalhães, Paulo; Alves, Gilberto; Llerena, A.; Fortuna, Ana; Falcão, Amílcar; Magalhães, P.; Alves, G.; Fortuna, A.; Falcão, A.. "Genetic characterization of the CYP2C9, CYP2C19, CYP2D6 isoenzymes and P-glycoprotein in Portuguese depressive patients". Paper presented in 47th ESPC Symposium on Clinical Pharmacy, 2018.
  48. Silva, Rui; Paulino, Jamal; Gonçalves, Joana; Silva, Ana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Levetiracetam therapy individualization: predictive performance of three pharmacokinetic models". Paper presented in 47th ESPC Symposium on Clinical Pharmacy, 2018.
  49. Ferreira, Ana; Rodrigues, Márcio; SANTOS, ADRIANA O.; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Potential of baicalein, (-)-epigallocatechin gallate, kaempferol, quercetin and silymarin and their dual combinations in reversing the P-glycoprotein-mediated antiepileptic drug resistance". Paper presented in 32nd International Epilepsy Congress, 2017.
  50. Ferreira, Ana; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Effects of the silymarin, a P-glycoprotein inhibitor, on the pharmacokinetics of oxcarbazepine and its active metabolite licarbazepine". Paper presented in II International Congress in Health Sciences Research: Towards Innovation and Entrepreneurship - Trends in Biotechnology for Biomedical Applications, 2017.
  51. Ferreira, Ana; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Flavonoids as potential reversing agents of the pharmacoresistance to antiepileptic drugs mediated by the P-glycoprotein". Paper presented in 12th European Congress on Epileptology, 2016.
  52. Oliveira, Susana; Fortuna, Ana; Rocha, Marília; Falcão, Amílcar. "Amikacin plasma monitoring in treating Portuguese patients infected with Acinetobacter baumannii". Paper presented in 44th ESCP Symposium on Clinical Pharmacy Lisbon, Portugal, 2015.
  53. Silva, Rui; Almeida, Anabela; Fortuna, Ana; Rocha, Marília; Falcão, Amílcar. "Phenytoin in pediatric patients: How important is the AEDs therapeutic drug monitoring?". Paper presented in 44th ESCP Symposium on Clinical Pharmacy, 2015.
  54. Fortuna, Ana; Alves, Gilberto; Bicker, Joana; Falcão, Amílcar. "Development of a new PAMPA method for the prediction of blood-brain barrier permeation using an in-house brain lipid extract". Paper presented in 17th International Symposium on Signal Transduction at the Blood-Brain and Blood-Retina Barriers, 2014.
  55. Serralheiro, Ana; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Avaliação do potencial da via intranasal para a administração de fármacos antiepiléticos: aplicação à carbamazepina". Paper presented in 26º Encontro Nacional de Epileptologia, 2014.
  56. Fortuna, Ana; Tavares, Ana; Couceiro, Paula; Alves, Gilberto; Falcão, Amílcar. "Medication regimen complexity evaluation in a hypertensive Portuguese population". Paper presented in 43rd European Symposium on Clinical Pharmacy, 2014.
  57. Fortuna, Ana; Magalhães, Paulo; Rodrigues, Marcio; Llerena, A.; Alves, Gilberto; Falcão, Amílcar. "A new MEPS/HPLC assay to quantify venlafaxine and its main metabolite in human plasma". Paper presented in 43rd European Symposium on Clinical Pharmacy, 2014.
  58. Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "In vitro screening and in vivo preclinical models fo r pharmacokinetic evaluation of carbamazepine and derivatives". Paper presented in Conferência Centro de Estudos Farmacêuticos (CEF), 2012.
  59. Sousa, Joana; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Quantification of ciprofloxacin in plasma and nasal mucosa matrices by high-performance liquid chromatography with fluorescence detection". Paper presented in 6th European Congress of Pharmacology, EPHAR, 2012.
  60. Serralheiro, Ana; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Fast HPLC-UV method for the simultaneous de termination of carbamazepine, lamotrigine, oxcarbazepine and phenytoin in mouse plasma, brain and liver tissues.". Paper presented in 6th European Congress of Pharmacology, EPHAR, 2012.
  61. Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "A new parallel artificial membrane permeability assay for estimation of intestinal absorption and protein binding in drug discovery programs". Paper presented in 6th European Congress of Pharmacology, EPHAR 20 12, 2012.
  62. Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Development of an in vitro bidirectional transport model for prediction of human drug absorption and assessment of P-glycoprotein involvement in intestinal drug absorption.". Paper presented in 6th European Congress of Pharmacology, EPHAR, 2012.
  63. Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Influence of plasma protein binding and efflux transport mediated by P-glycoprotein on the enantioselective biodisposition of eslicarbazepine and R-licarbazepine.". Paper presented in 6th European Congress of Pharmacology, EPHAR, 2012.
  64. Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Plasma and brain pharmacokinetic profiles of carbamazepine and nine derivatives after oral administration to mice: implications for selection of drug candidates.". Paper presented in 6th European Congress of Pharmacology, EPHAR, 2012.
  65. Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Avaliação farmacométrica in silico, in vitro e in viv o da carbamazepina e análogos estruturais.". Paper presented in 24º Encontro Nacional de Epileptologia, 2012.
  66. Sousa, Joana; Alves, Gilberto; Fortuna, Ana; Falcão, Amílcar. "Determination of norfloxacin, ciprofloxacin and lemofloxacin in hum an plasma by a simple and rapid liquid chromatographic method.". Paper presented in Conferência Ibero-Americana de Faculdades de Farmácia, 2011.
  67. Fortuna, Ana; Bicker, Joana; Mesquita, Inês; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Development of an enantioselective high performance liquid chromatography analysis of dibenz[b,f]azepine-5- carboxamide derivatives in mouse plasma and brain.". Paper presented in Conferência Ibero-Americana de Faculdades de Farmácia, 2011.
  68. Fortuna, Ana; Bicker, Joana; Mesquita, Inês; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "A rapid and robust HPLC-UV method for simultaneous quantification of three generations of anti-epileptic drugs in human plasma: carbamazepine, oxcarbazepine and eslicarbazepine acetate.". Paper presented in Conferência Ibero-Americana de Faculdades de Farmácia, 2011.
  69. Fortuna, Ana; Bicker, Joana; Mesquita, Inês; Alves Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Predicting human drug absorption with Parallel Artificial Membrane Permeability Assay.". Paper presented in Conferência Ibero-Americana de Faculdades de Farmácia, 2011.
  70. Fortuna, Ana; Bicker, Joana; Mesquita, Inês; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Assessment of the involvement of P-glycoprotein in intestinal drug absorption during drug discovery". Paper presented in Conferência Ibero-Americana de Faculdades de Farmácia, 2011.
  71. Serralheiro, Ana; Bicker, Joana; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Novel HPLC-UV method to monitor plasma concentrations of six antiepileptic drugs and three of their main metabolites in patients with epilepsy.". Paper presented in Conferência Ibero-America na de Faculdades de Farmácia, 2011.
  72. Fortuna, Ana; Direito, Rosa; Alves, Gilberto; Sousa, Joana; Falcão, Amílcar; Cabrita, A.. "Morphological evaluation of rat liver tissue after the subcutaneous injection of 1,2-dimethylhydrazine". Paper presented in WorldPharma2010 – 16th IUPHAR World Congress on Basis and Clinical Pharmacology, 2010.
  73. Fortuna, Ana; Sousa, Joana; Direito, Rosa; Rocha, Marília; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Lack of interference of Carbamazepine and its metabolites in the enantioselective therapeutic drug monitoring of eslicarbazepine acetate". Paper presented in WorldPharma2010 – 16th I UPHAR World Congress on Basis and Clinical Pharmacology, 2010.
  74. Fortuna, Ana; Alves, Gilberto; Santos, L.; Falcão, Amílcar; Soares-Da-Silva, Patrício. "A rapid and sensitive high-performance liquid chromatographic method to quantify carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites in human plasma.". Paper presented in WorldPharma2010 – 16th IUPHAR World Congress on Basis and Clinical Pharmacology, 2010.
  75. Alves, Gilberto; Nunes, Teresa; Fortuna, Ana; Rodrigues, Márcio; Serralheiro, Ana; Falcão, Amílcar; Soares-da-Silva, Patrício. "Kidney drug exposure after multiple-dose administration of S- and R-licarbazepine to mice". Paper presented in 38th American College of Clinical Pharmacology Annual Meeting. San Antonio (Texas)/Estados Unidos da América,, 2009.
  76. Serralheiro, Ana ; Alves, Gilberto; Nunes, T.; Fortuna, Ana; Rodrigues, Márcio; Falcão, Amílcar; Soares-da-Silva, P.. "Plasma-brain distribution of licarbazapine enantiomers in mice on steady-state conditions". Paper presented in 38th American College of Clinical Pharmacology Annual Meeting, 2009.
  77. Alves, Gilberto; Nunes, T.; Fortuna, Ana; Rodrigues, Marcio; Serralheiro, Ana; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Plasma-brain distribution of licarbazepine enantiomers in mice on steady-state conditions.". Paper presented in 38th American College of Clinical Pharmacology Annual Meeting, 2009.
  78. Alves, Gilberto; Nunes, T.; Fortuna, Ana; Serralheiro, Ana; Rodrigues, Marcio; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Metabolism and liver pharmacokinetics of S- and R-licarbazepine in mice at the steady-state.". Paper presented in 38th American College of Clinical Pharmacology Annual Meeting, 2009.
  79. Caramona, Margarida; Fortuna, Ana; Alves, Gilberto; Pereira, C.; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Human plasma protein binding of S- and R-licarbazepine". Paper presented in XVIII CONGRESO de la Asociación Latinoamericana de Farmacología; XXX Reunión Anual Socie dad de Farmacología de Chile; XXIII Sociedad Chilena de Ciencias Fisiológicas; III Congreso Iberoamericano de Farmacología., 2009.
  80. Fortuna, Ana; Pires, Ana; Silva, R.; Gaio, Daniel; Alves, Gilberto; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Plasma protein binding of licarbazepine enantiomers in human and mouse species.". Paper presented in 1st International Epilepsy Colloquium, 2008.
  81. Fortuna, Ana; Caramona, Margarida; Alves, Gilberto; Pereira, C.; Falcão, Amílcar; Soares-Da-Silva, Patrício. "Binding of licarbazepine enantiomers to human serum albumin and alpha-1-a cid glycoprotein.". Paper presented in XVIII CONGRESO de la Asociación Latinoamericana de Farmacología; XXX Reunión Anual Socie dad de Farmacología de Chile; XXIII Sociedad Chilena de Ciencias Fisiológicas; III Congreso Iberoamericano de Farmacología., 2008.
  82. Almeida, Anabela; Fortuna, Ana; Pires, Anaisa; Gaio, Daniel; Silva, R.; Silva, H.; Alves, Gilberto; Falcão, Amílcar. "Lamotrigine in patients submitted to video-electroencephalographic monitoring : effect of co-medication in temporal and extratemporal epilepsy". Paper presented in 1st International Epilepsy Colloquium., 2007.
  83. Alves, Gilberto; Figueiredo, I.; Castel-Branco, M.; Loureiro, A. I.; Fortuna, Ana; Falcão, Amílcar; Caramona, Margarida. "Enantioselective HPLC-UV Assay for Eslicarbazepine Acetate (BIA 2-093) and its metabolites determination in mice plasma and tissues: application to pharmacokinetic studies.". Paper presented in Pharmaceutical Sciences World Congress (PSWC) – 3rd World Congress of the Board of Pharmaceutical Sciences of FIP., 2007.
Journal article
  1. Soraia Silva; Joana Bicker; S. Fialho; Cunha, Susana; Amílcar Falcão; Fortuna, Ana. "Intranasal delivery of paroxetine: A preclinical study on pharmacokinetics, depressive-like behaviour, and neurochemical sex differences". Biochemical Pharmacology (2024): https://doi.org/10.1016/j.bcp.2024.116184.
    10.1016/j.bcp.2024.116184
  2. Santos, A.B.; Carona, Andreia; Ettcheto, Miren; Camins, Antoni; Falcão Amílcar; Fortuna, Ana; Bicker, Joana. "Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis". Acta Pharmacologica Sinica (2024):
    Accepted • 10.1038/s41401-024-01285-w
  3. Filipa Gouveia; Carla Fonseca; Ana Silva; Antoni Camins; M. Teresa Cruz; Miren Ettcheto; Ana Fortuna. "Intranasal irbesartan reverts cognitive decline and activates the PI3K/AKT pathway in an LPS-induced neuroinflammation mice model". International Immunopharmacology (2024): https://doi.org/10.1016/j.intimp.2023.111471.
    10.1016/j.intimp.2023.111471
  4. Soraia Silva; Carla Fonseca; Joana Bicker; Amílcar Falcão; Ana Fortuna. "Intranasal administration of sertraline ensures sustained brain delivery and antidepressant effect in a mouse model of depression". European Journal of Pharmaceutics and Biopharmaceutics (2024): https://doi.org/10.1016/j.ejpb.2023.12.002.
    10.1016/j.ejpb.2023.12.002
  5. Carla Fonseca; Cunha, Susana; Lapo Pais, Mariana; 3412-D57F-07A9; Ferreira, Nuno Ricardo Esteves; Antoni, Camins; Ettcheto, Miren; 5B16-6FC6-725F; Fortuna, Ana. "Cannabinoid Modulation of Monoamine Levels in Mouse Brain: Unveiling Neurochemical Dynamics through an Innovative High-performance Liquid Chromatography-Fluorescence Detection Bioanalysis". Journal of Analysis and Testing (2024):
    Accepted • 10.1007/s41664-024-00307-0
  6. Cunha, Susana; Bicker, Joana; Sereno, José Vitor Oliveira; Fortuna, Ana. "The blood brain barrier dysfunction in healthy aging and dementia: why, how, what for?". Ageing Research Reviews (2024):
    Under revision
  7. Olloquequi, Jordi; Ettcheto, Miren; Cano, Amanda; Fortuna, Ana; Bicker, Joana; Sánchez-Lopez, Elena; Paz, Cristian; et al. "Licochalcone A: A Potential Multitarget Drug for Alzheimer’s Disease Treatment". International Journal of Molecular Sciences 24 18 (2023): 14177. http://dx.doi.org/10.3390/ijms241814177.
    10.3390/ijms241814177
  8. Fonseca, Carla; Ettcheto, Miren; Bicker, Joana; Fernandes, Maria José; Falcão, Amílcar; Camins, Antoni; Fortuna, Ana. "Under the umbrella of depression and Alzheimer’s disease physiopathology: Can cannabinoids be a dual-pleiotropic therapy?". Ageing Research Reviews 90 (2023): 101998. http://dx.doi.org/10.1016/j.arr.2023.101998.
    10.1016/j.arr.2023.101998
  9. Henriques, Patrícia; Bicker, Joana; Carona, Andreia; Miranda, Margarida; Vitorino, Carla; Doktorovová, Slavomíra; Fortuna, Ana. "Amorphous nasal powder advanced performance: in vitro/ex vivo studies and correlation with in vivo pharmacokinetics". Journal of Pharmaceutical Investigation 53 5 (2023): 723-742. http://dx.doi.org/10.1007/s40005-023-00630-1.
    10.1007/s40005-023-00630-1
  10. Henriques, Patrícia; Bicker, Joana; Silva, Soraia; Doktorovová, Slavomíra; Fortuna, Ana. "Nasal-PAMPA: A novel non-cell-based high throughput screening assay for prediction of nasal drug permeability". International Journal of Pharmaceutics 643 (2023): 123252. http://dx.doi.org/10.1016/j.ijpharm.2023.123252.
    10.1016/j.ijpharm.2023.123252
  11. Silva, Rui; Colom, Helena; Bicker, Joana; Almeida, Anabela; Silva, Ana; Sales, Francisco; Santana, Isabel; Falcão, Amílcar; Fortuna, Ana. "Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory Epilepsy". Pharmaceutics 15 6 (2023): 1704. http://dx.doi.org/10.3390/pharmaceutics15061704.
    10.3390/pharmaceutics15061704
  12. Soraia Silva; Joana Bicker; Amílcar Falcão; Ana Fortuna. "Air-liquid interface (ALI) impact on different respiratory cell cultures". European Journal of Pharmaceutics and Biopharmaceutics (2023): https://doi.org/10.1016/j.ejpb.2023.01.013.
    10.1016/j.ejpb.2023.01.013
  13. Maria Aquino; Maria Tinoco; Joana Bicker; Amílcar Falcão; Marília Rocha; Ana Fortuna. "Therapeutic Drug Monitoring of Amikacin in Neutropenic Oncology Patients". Antibiotics (2023): https://doi.org/10.3390/antibiotics12020373.
    10.3390/antibiotics12020373
  14. Aquino, Maria; Tinoco, Maria; Bicker, Joana; Falcão, Amílcar; Rocha, Marília; Fortuna, Ana. "Therapeutic Drug Monitoring of Amikacin in Neutropenic Oncology Patients". Antibiotics 12 2 (2023): 373. http://dx.doi.org/10.3390/antibiotics12020373.
    10.3390/antibiotics12020373
  15. Ferreira, Nuno R.; Vitorino, Carla; Fortuna, Ana. "From antioxidant to neuromodulator: The role of ascorbate in the management of major depression disorder". Biochemical Pharmacology 206 (2022): 115300. http://dx.doi.org/10.1016/j.bcp.2022.115300.
    Published • 10.1016/j.bcp.2022.115300
  16. Silva, Rui; Bicker, Joana; Almeida, Anabela; Carona, Andreia; Silva, Ana; Sales, Francisco; Santana, Isabel; Falcão, Amílcar; Fortuna, Ana. "Clinical Application of Pharmacokinetics to Appraise Adherence to Levetiracetam in Portuguese Epileptic Patients". Biomedicines 10 9 (2022): 2127. http://dx.doi.org/10.3390/biomedicines10092127.
    Published • 10.3390/biomedicines10092127
  17. Meirinho, Sara; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Study of the metabolic stability profiles of perampanel, rufinamide and stiripentol and prediction of drug interactions using HepaRG cells as an in vitro human model". Toxicology in Vitro (2022): 105389. http://dx.doi.org/10.1016/j.tiv.2022.105389.
    In press • 10.1016/j.tiv.2022.105389
  18. Meirinho, Sara; Rodrigues, Márcio; Ferreira, Catarina L.; Oliveira, Rui Caetano; Fortuna, Ana; SANTOS, ADRIANA O.; Falcão, Amílcar; Alves, Gilberto. Corresponding author: Alves, Gilberto. "Intranasal delivery of lipid-based nanosystems as a promising approach for brain targeting of the new-generation antiepileptic drug perampanel". International Journal of Pharmaceutics 622 (2022): 121853. http://dx.doi.org/10.1016/j.ijpharm.2022.121853.
    10.1016/j.ijpharm.2022.121853
  19. Fortuna, Ana; Schindowski, Katharina; Sonvico, Fabio. Corresponding author: Fortuna, Ana. "Editorial: Intranasal Drug Delivery: Challenges and Opportunities". Frontiers in Pharmacology 13 (2022): http://dx.doi.org/10.3389/fphar.2022.868986.
    10.3389/fphar.2022.868986
  20. Basso, João; Paggi, Marco G.; Fortuna, Ana; Vitorino, Carla; Vitorino, Rui. "Deciphering specific miRNAs in brain tumors: a 5-miRNA signature in glioblastoma". Molecular Genetics and Genomics (2022): http://dx.doi.org/10.1007/s00438-022-01866-6.
    10.1007/s00438-022-01866-6
  21. Basso, João; Mendes, Maria; Cova, Tânia; Sousa, João; Pais, Alberto; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "A Stepwise Framework for the Systematic Development of Lipid Nanoparticles". Biomolecules 12 2 (2022): 223. http://dx.doi.org/10.3390/biom12020223.
    10.3390/biom12020223
  22. Silva, Soraia; Bicker, Joana; Fonseca, Carla; Ferreira, Nuno R.; Vitorino, Carla; Alves, Gilberto; Falcão, Amílcar; Fortuna, Ana. "Encapsulated Escitalopram and Paroxetine Intranasal Co-Administration: In Vitro/In Vivo Evaluation". Frontiers in Pharmacology 12 (2021): http://dx.doi.org/10.3389/fphar.2021.751321.
    10.3389/fphar.2021.751321
  23. Silva, Soraia; Bicker, Joana; Falcão, Amílcar; Fortuna, Ana. "Antidepressants and Circadian Rhythm: Exploring Their Bidirectional Interaction for the Treatment of Depression". Pharmaceutics 13 11 (2021): 1975. http://dx.doi.org/10.3390/pharmaceutics13111975.
    10.3390/pharmaceutics13111975
  24. Silva, Nuno; Fortuna, Ana; Salgueiro, Lígia; Cavaleiro, Carlos. "The essential oil from the fruits of Peucedanum oreoselinum (L.) Moench (Apiaceae) as a natural source of P-glycoprotein inhibitors". Journal of Herbal Medicine 29 (2021): 100482. http://dx.doi.org/10.1016/j.hermed.2021.100482.
    10.1016/j.hermed.2021.100482
  25. Meirinho, Sara; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Liquid chromatographic methods for determination of the new antiepileptic drugs stiripentol, retigabine, rufinamide and perampanel: A comprehensive and critical review". Journal of Pharmaceutical Analysis 11 4 (2021): 405-421. http://dx.doi.org/10.1016/j.jpha.2020.11.005.
    10.1016/j.jpha.2020.11.005
  26. Basso, João; Ramos, Maria Luísa; Pais, Alberto; Vitorino, Rui; Fortuna, Ana; Vitorino, Carla. "Expediting Disulfiram Assays through a Systematic Analytical Quality by Design Approach". Chemosensors 9 7 (2021): 172. http://dx.doi.org/10.3390/chemosensors9070172.
    10.3390/chemosensors9070172
  27. Andreia Carona; Joana Bicker; Rui Silva; Ana Silva; Isabel Santana; Francisco Sales; Amílcar Falcão; Ana Fortuna. "HPLC method for the determination of antiepileptic drugs in human saliva and its application in therapeutic drug monitoring". Journal of Pharmaceutical and Biomedical Analysis (2021): 113961-113961. https://doi.org/10.1016/j.jpba.2021.113961.
    10.1016/j.jpba.2021.113961
  28. Carona, Andreia; Bicker, Joana; Silva, Rui; Fonseca, Carla; Falcão, Amílcar; Fortuna, Ana. "Pharmacology of lacosamide: From its molecular mechanisms and pharmacokinetics to future therapeutic applications". Life Sciences (2021): 119342. http://dx.doi.org/10.1016/j.lfs.2021.119342.
    10.1016/j.lfs.2021.119342
  29. Joana Gonçalves; Gilberto Alves; Carla Fonseca; Andreia Carona; Joana Bicker; Amílcar Falcão; Ana Fortuna. "Is intranasal administration an opportunity for direct brain delivery of lacosamide?". European Journal of Pharmaceutical Sciences 157 (2021): 105632-105632. https://doi.org/10.1016/j.ejps.2020.105632.
    10.1016/j.ejps.2020.105632
  30. Joana Gonçalves; Soraia Silva; Filipa Gouveia; Joana Bicker; Amílcar Falcão; Gilberto Alves; Ana Fortuna. "A combo-strategy to improve brain delivery of antiepileptic drugs: Focus on BCRP and intranasal administration". International Journal of Pharmaceutics 593 (2021): 120161-120161. https://doi.org/10.1016/j.ijpharm.2020.120161.
    10.1016/j.ijpharm.2020.120161
  31. Sabença, Rosa; Bicker, Joana; Silva, Rui; Carona, Andreia; Silva, Ana; Santana, Isabel; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Development and application of an HPLC-DAD technique for human plasma concentration monitoring of perampanel and lamotrigine in drug-resistant epileptic patients". Journal of Chromatography B 1162 (2021): 122491. http://dx.doi.org/10.1016/j.jchromb.2020.122491.
    10.1016/j.jchromb.2020.122491
  32. Carla Fonseca; Joana Bicker; Gilberto Alves; Amílcar Falcão; Ana Fortuna. "Cystic fibrosis: Physiopathology and the latest pharmacological treatments". Pharmacological Research (2020): 105267-105267. https://doi.org/10.1016/j.phrs.2020.105267.
    10.1016/j.phrs.2020.105267
  33. Bicker, Joana; Alves, Gilberto; Fonseca, Carla; Falcão, Amílcar; Fortuna, Ana. "Repairing blood-CNS barriers: Future therapeutic approaches for neuropsychiatric disorders". Pharmacological Research 162 (2020): 105226. http://dx.doi.org/10.1016/j.phrs.2020.105226.
    10.1016/j.phrs.2020.105226
  34. Meirinho, Sara; Campos, Gonçalo; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Salting-out assisted liquid–liquid extraction method optimized by design of experiments for the simultaneous high-performance liquid chromatography analysis of perampanel and stiripentol in mouse matrices". Journal of Separation Science 43 23 (2020): 4289-4304. http://dx.doi.org/10.1002/jssc.202000656.
    10.1002/jssc.202000656
  35. Silva, Rui; Almeida, Anabela; Bicker, Joana; Gonçalves, Joana; Carona, Andreia; Silva, Ana; Santana, Isabel; et al. "Pharmacokinetic Monitoring of Levetiracetam in Portuguese Refractory Epileptic Patients: Effect of Gender, Weight and Concomitant Therapy". Pharmaceutics 12 10 (2020): 943. http://dx.doi.org/10.3390/pharmaceutics12100943.
    10.3390/pharmaceutics12100943
  36. Basso, João; Mendes, Maria; Silva, Jessica; Sereno, José; Cova, Tânia; Oliveira, Rui; Fortuna, Ana; et al. "Peptide-lipid nanoconstructs act site-specifically towards glioblastoma growth impairment". European Journal of Pharmaceutics and Biopharmaceutics 155 (2020): 177-189. http://dx.doi.org/10.1016/j.ejpb.2020.08.015.
    10.1016/j.ejpb.2020.08.015
  37. Joana Gonçalves; Gilberto Alves; Andreia Carona; Joana Bicker; Carla Vitorino; Amílcar Falcão; Ana Fortuna. "Pre-Clinical Assessment of the Nose-to-Brain Delivery of Zonisamide After Intranasal Administration". Pharmaceutical Research 37 4 (2020): https://doi.org/10.1007/s11095-020-02786-z.
    10.1007/s11095-020-02786-z
  38. Gouveia, Filipa; Bicker, Joana; Santos, Joana; Rocha, Marília; Alves, Gilberto; Falcão, Amílcar; Fortuna, Ana. "Development, validation and application of a new HPLC-DAD method for simultaneous quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma". Journal of Pharmaceutical and Biomedical Analysis 181 (2020): 113109. http://dx.doi.org/10.1016/j.jpba.2020.113109.
    10.1016/j.jpba.2020.113109
  39. Joana Bicker; Gilberto Alves; Amílcar Falcão; Ana Fortuna. "Timing in drug absorption and disposition: the past, present and future of chronopharmacokinetics". British Journal of Pharmacology (2020): https://doi.org/10.1111/bph.15017.
    10.1111/bph.15017
  40. Joana Bicker; Ana Fortuna; Gilberto Alves; Amílcar Falcão. "Nose-to-brain Delivery of Natural Compounds for the Treatment of Central Nervous System Disorders". Current Pharmaceutical Design (2020): https://doi.org/10.2174/1381612826666200115101544.
    10.2174/1381612826666200115101544
  41. Carla Vitorino; Soraia Silva; Filipa Gouveia; Joana Bicker; Amílcar Falcão; Fortuna, Ana. "QbD-driven development of intranasal lipid nanoparticles for depression treatment". European Journal of Pharmaceutics and Biopharmaceutics (2020): https://authors.elsevier.com/tracking/article/details.do?aid=13274&jid=EJPB&surname=Fortuna.
    Published
  42. Joana Santos; Natália António; Marília Rocha; Ana Fortuna. "Impact of direct oral anticoagulants off-label doses on clinical outcomes of atrial fibrillation patients: a systematic review". British Journal of Clinical Pharmacology (2019): https://doi.org/10.1111/bcp.14127.
    10.1111/bcp.14127
  43. Vieira; Souto; Sánchez-López; Machado; Severino; Jose; Santini; et al. "Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome—Review of Classical and New Compounds: Part-I". Pharmaceuticals 12 4 (2019): 152. http://dx.doi.org/10.3390/ph12040152.
    10.3390/ph12040152
  44. Filipa Gouveia; Joana Bicker; Joana Gonçalves; Gilberto Alves; Amílcar Falcão; Ana Fortuna; Gouveia, Filipa; et al. "Liquid chromatographic methods for the determination of direct oral anticoagulant drugs in biological samples: A critical review". Analytica Chimica Acta (2019): https://doi.org/10.1016/j.aca.2019.03.061.
    Published • 10.1016/j.aca.2019.03.061
  45. Meirinho, Sara; Rodrigues, Márcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Novel bioanalytical method for the quantification of rufinamide in mouse plasma and tissues using HPLC-UV: A tool to support pharmacokinetic studies". Journal of Chromatography B 1124 (2019): 340-348. http://dx.doi.org/10.1016/j.jchromb.2019.06.021.
    10.1016/j.jchromb.2019.06.021
  46. Silva, Jessica; Basso, João; Sousa, João; Fortuna, Ana; Vitorino, Carla. "Development and full validation of an HPLC methodology to quantify atorvastatin and curcumin after their intranasal co-delivery to mice". Biomedical Chromatography 33 10 (2019): http://dx.doi.org/10.1002/bmc.4621.
    10.1002/bmc.4621
  47. Joana Gonçalves; Joana Bicker; Filipa Gouveia; Joana Liberal; Rui Caetano Oliveira; Gilberto Alves; Amílcar Falcão; Ana Fortuna. "Nose-to-brain delivery of levetiracetam after intranasal administration to mice". International Journal of Pharmaceutics (1st quartile) (2019): https://doi.org/10.1016/j.ijpharm.2019.04.047.
    10.1016/j.ijpharm.2019.04.047
  48. Santos, Joana; Fortuna, Ana; Rocha, Marília; Mendes, Ana Rita; António, Natália. "Posters". European Journal of Clinical Investigation 49 S1 (2019): 101-221. http://dx.doi.org/10.1111/eci.13109.
    10.1111/eci.13109
  49. Ferreira, Ana; Rodrigues, Marcio; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Silymarin as a Flavonoid-Type P-Glycoprotein Inhibitor with impact on the Pharmacokinetics of Carbamazepine, Oxcarbazepine and Phenytoin in Rats". Drug and Chemical Toxicology (2019):
    Published
  50. Magalhães, Paulo; Llerena, A.; Fortuna, Ana; Falcão, Amílcar; Alves, Gilberto. "Real-world clinical characterization of subjects with depression treated with antidepressant drugs focused on (non-)genetic factors, pharmacokinetics and clinical outcomes: GnG-PK/PD-AD study". Experimental and Clinical Psychopharmacology (2019):
    Published
  51. Santos, Ana Claudia; Veiga, Francisco; Joana A. D. Sequeira; Fortuna, Ana; Falcão, Amílcar; Pereira, Irina; Pattekari, Pravin; Fontes-Ribeiro, Carlos; Ribeiro, António. "First-time oral administration of resveratrol-loaded layer-by-layer nanoparticles to rats – a pharmacokinetics study". The Analyst 144 6 (2019): 2062-2079. https://doi.org/10.1039/C8AN01998C.
    10.1039/C8AN01998C
  52. Magalhães, P.; Alves, G.; Fortuna, A.; Llerena, A.; Falcão, A.. "Real-World Clinical Characterization of Subjects With Depression Treated With Antidepressant Drugs Focused on (Non-)Genetic Factors, Pharmacokinetics, and Clinical Outcomes: GnG-PK/PD-AD Study". Experimental and Clinical Psychopharmacology (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85065972663&partnerID=MN8TOARS.
    10.1037/pha0000294
  53. Ana, R.; Mendes, M.; Sousa, J.; Pais, A.; Falcão, A.; Fortuna, A.; Vitorino, C.. "Rethinking carbamazepine oral delivery using polymer-lipid hybrid nanoparticles". International Journal of Pharmaceutics 554 (2019): 352-365. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056766454&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2018.11.028
  54. Pinho, A.R.; Fortuna, A.; Falcão, A.; Santos, A.C.; Seiça, R.; Estevens, C.; Veiga, F.; Ribeiro, A.J.. "Comparison of ELISA and HPLC-MS methods for the determination of exenatide in biological and biotechnology-based formulation matrices". Journal of Pharmaceutical Analysis 9 3 (2019): 143-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065783299&partnerID=MN8TOARS.
    10.1016/j.jpha.2019.02.001
  55. Leandro, K.; Bicker, J.; Alves, G.; Falcão, A.; Fortuna, A.. "ABC transporters in drug-resistant epilepsy: mechanisms of upregulation and therapeutic approaches". Pharmacological Research 144 (2019): 357-376. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065627363&partnerID=MN8TOARS.
    10.1016/j.phrs.2019.04.031
  56. Vitorino, C.; Silva, S.; Bicker, J.; Falcão, A.; Fortuna, A.. "Antidepressants and nose-to-brain delivery: drivers, restraints, opportunities and challenges". Drug Discovery Today (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067172382&partnerID=MN8TOARS.
    10.1016/j.drudis.2019.06.001
  57. Ferreira, A.; Rodrigues, M.; Meirinho, S.; Fortuna, A.; Falcão, A.; Alves, G.. "Silymarin as a flavonoid-type P-glycoprotein inhibitor with impact on the pharmacokinetics of carbamazepine, oxcarbazepine and phenytoin in rats". Drug and Chemical Toxicology (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85065181492&partnerID=MN8TOARS.
    10.1080/01480545.2019.1601736
  58. Gonçalves, Joana; Bicker, Joana; Gilberto Alves; Fortuna, Ana; Falcão, Amílcar. "Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective". Current Drug Metabolism 19 12 (2018): 1021-1041. https://doi.org/10.2174%2F1389200219666180629121033.
    10.2174/1389200219666180629121033
  59. Gonçalves J; Alves G; Bicker J; Falcão A; Fortuna A. "Development and full validation of an innovative HPLC-diode array detection technique to simultaneously quantify lacosamide, levetiracetam and zonisamide in human plasma.". Bioanalysis (2018): http://europepmc.org/abstract/med/29561632.
    10.4155/bio-2017-0199
  60. Bicker J; Alves G; Fortuna A; Soares-da-Silva P; Falcão A. "In vitro assessment of the interactions of dopamine ß-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein.". European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2018): http://europepmc.org/abstract/med/29428540.
    10.1016/j.ejps.2018.02.006
  61. Ferreira, A.; Rodrigues, M.; Fortuna, A,; Falcão, A.; Alves, G.. "Flavonoid compounds as reversing agents of the P-glycoprotein-mediated multidrug resistance: An in vitro evaluation with focus on antiepileptic drugs.". Food research international. (2018): http://europepmc.org/abstract/med/29389596.
    10.1016/j.foodres.2017.10.010
  62. A. R. Pinho; M. J. Rocha; G. Alves; A. C. Falcão; A. C. Fortuna. "Development and validation of an HPLC-FLD technique for colistin quantification and its plasma monitoring in hospitalized patients". Analytical Methods 10 3 (2018): 389-396. https://doi.org/10.1039/C7AY02585H.
    10.1039/C7AY02585H
  63. Campos, G.; Fortuna, A.; Falcão, A.; Alves, G.. "In vitro and in vivo experimental models employed in the discovery and development of antiepileptic drugs for pharmacoresistant epilepsy". Epilepsy Research 146 (2018): 63-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050938227&partnerID=MN8TOARS.
    10.1016/j.eplepsyres.2018.07.008
  64. Bicker, Joana; Fortuna, Ana; Alves, Gilberto; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Elucidation of the Impact of P-glycoprotein and Breast Cancer Resistance Protein on the Brain Distribution of Catechol-O-Methyltransferase Inhibitors.". Drug metabolism and disposition: the biological fate of chemicals (2017): http://europepmc.org/abstract/med/28916530.
    10.1124/dmd.117.077883
  65. Sousa, Joana; Alves, Gilberto; Fortuna, Ana; Falcão, Amílcar. "Intranasal Delivery of Topically-Acting Levofloxacin to Rats: a Proof-of-Concept Pharmacokinetic Study.". Pharmaceutical research (2017): http://europepmc.org/abstract/med/28748398.
    10.1007/s11095-017-2232-1
  66. Matias, Mariana; Fortuna, Ana; Bicker, Joana; Silvestre, Samuel; Falcão, Amílcar; Alves, Gilberto. "Screening of pharmacokinetic properties of fifty dihydropyrimidin(thi)one derivatives using a combo of in vitro and in silico assays.". European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2017): http://europepmc.org/abstract/med/28842351.
    10.1016/j.ejps.2017.08.023
  67. Gonçalves, Daniela; Alves, Gilberto; Fortuna, Ana; Bonifácio, Maria João; Soares-Da-Silva, Patrício; Falcão, Amílcar. "A single- and multiple-dose study to investigate the pharmacokinetics and pharmacodynamics of opicapone, a novel COMT inhibitor, in rat.". Neuropharmacology (2017): http://europepmc.org/abstract/med/28734868.
    10.1016/j.neuropharm.2017.07.019
  68. Gonçalves, Daniela; Alves, Gilberto; Fortuna, Ana; Soares-Da-Silva, Patrício; Falcão, Amílcar. "Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat.". Toxicology and applied pharmacology (2017): http://europepmc.org/abstract/med/28322896.
    10.1016/j.taap.2017.03.013
  69. Fonseca, Beatriz; Rodrigues, Márcio; Cristovão, A.; Gonçalves, Daniela; Fortuna, Ana; Bernardino, L.; Falcão, Amílcar; Alves, Gilberto. "Determination of catecholamines and endogenous related compounds in rat brain tissue exploring their native fluorescence and liquid chromatography.". Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (2017): http://europepmc.org/abstract/med/28273522.
    10.1016/j.jchromb.2017.02.028
  70. Sousa, Joana; Alves, Gilberto; Fortuna, Ana; Oliveira, Paula; Falcão, Amílcar. "Intranasal delivery of ciprofloxacin to rats: A topical approach using a thermoreversible in situ gel.". European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2017): http://europepmc.org/abstract/med/27810560.
    10.1016/j.ejps.2016.10.033
  71. Gustavo Costa; Ana Fortuna; Daniela Gonçalves; Isabel Vitoria Figueiredo; Amilcar Falcao; Maria Teresa Batista; Fortuna, Ana. "Pharmacokinetics of Cymbopogon Citratus Infusion in Rats after Single Oral Dose Administration". SOJ Pharmacy & Pharmaceutical Sciences 4 3 (2017): 1-9. https://doi.org/10.15226%2F2374-6866%2F4%2F3%2F00160.
    10.15226/2374-6866/4/3/00160
  72. Gonçalves, Carmen; Rocha, Marília; Gonçalves, Joana; Falcão, Amílcar; Ana Fortuna. "Effect of Kidney Function on Amikacin Pharmacokinetics on Hospitalized Patients: Knowledge to Improve Therapy". Bioequivalence & Bioavailability International Journal 1 2 (2017): https://doi.org/10.23880%2Fbeba-16000107.
    10.23880/beba-16000107
  73. Bicker, Joana; Alves, Gilberto; Soares-Da-Silva, Patrício; Fortuna, Ana; Falcão, Amílcar. "A new PAMPA model using an in-house brain lipid extract for screening the blood-brain barrier permeability of drug candidates.". International journal of pharmaceutics (2016): http://europepmc.org/abstract/med/26836708.
    10.1016/j.ijpharm.2016.01.074
  74. Oliveira, Paula; Fortuna, Ana; Alves, Gilberto; Falcão, Amílcar. "Drug-metabolizing Enzymes and Efflux Transporters in Nasal Epithelium: Influence on the Bioavailability of Intranasally Administered Drugs.". Current drug metabolism (2016): http://europepmc.org/abstract/med/27048181.
    10.2174/1389200217666160406120509
  75. Silva, N.; Salgueiro, L.; Fortuna, A.; Cavaleiro, C.. "P-glycoprotein mediated efflux modulators of plant origin: A short review". Natural Product Communications 11 5 (2016): 699-704. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982133188&partnerID=MN8TOARS.
  76. Gonçalves, Daniela; Alves, Gilberto; Fortuna, Ana; Soares-da-Silva, Patrício; Falcão, Amílcar. "Development of a liquid chromatography assay for the determination of opicapone and BIA 9-1079 in rat matrices". Biomedical Chromatography 30 3 (2015): 312-322. http://dx.doi.org/10.1002/bmc.3550.
    10.1002/bmc.3550
  77. Serralheiro, A.; Alves, G.; Fortuna, A.; Falcão, A.. "Direct nose-to-brain delivery of lamotrigine following intranasal administration to mice". International Journal of Pharmaceutics 490 1-2 (2015): 39-46. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929996693&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2015.05.021
  78. Ana Ferreira; Márcio Rodrigues; Ana Fortuna; Amílcar Falcão; Gilberto Alves. "Huperzine A from Huperzia serrata: a review of its sources, chemistry, pharmacology and toxicology". Phytochemistry Reviews 15 1 (2014): 51-85. https://doi.org/10.1007%2Fs11101-014-9384-y.
    10.1007/s11101-014-9384-y
  79. Ana Serralheiro; Gilberto Alves; Ana Fortuna; Amílcar Falcão. "Intranasal administration of carbamazepine to mice: A direct delivery pathway for brain targeting". European Journal of Pharmaceutical Sciences 60 (2014): 32-39. https://doi.org/10.1016%2Fj.ejps.2014.04.019.
    10.1016/j.ejps.2014.04.019
  80. Márcio Rodrigues; Gilberto Alves; Joana Francisco; Ana Fortuna; Amílcar Falcão. "Herb-drug Pharmacokinetic Interaction between Carica Papaya Extract and Amiodarone in Rats". Journal of Pharmacy & Pharmaceutical Sciences 17 3 (2014): 302-302. https://doi.org/10.18433%2Fj3559n.
    10.18433/j3559n
  81. Ana Ferreira; Sarah Pousinho; Ana Fortuna; Amílcar Falcão; Gilberto Alves. "Flavonoid compounds as reversal agents of the P-glycoprotein-mediated multidrug resistance: biology, chemistry and pharmacology". Phytochemistry Reviews 14 2 (2014): 233-272. https://doi.org/10.1007%2Fs11101-014-9358-0.
    10.1007/s11101-014-9358-0
  82. Joana Sousa; Gilberto Alves; Ana Fortuna; Amilcar Falcao. "Third and Fourth Generation Fluoroquinolone Antibacterials: A Systematic Review of Safety and Toxicity Profiles". Current Drug Safety 9 2 (2014): 89-105. https://doi.org/10.2174%2F1574886308666140106154754.
    10.2174/1574886308666140106154754
  83. Fortuna, A.; Alves, G.; Falcão, A.. "Chiral chromatographic resolution of antiepileptic drugs and their metabolites: A challenge from the optimization to the application". Biomedical Chromatography 28 1 (2014): 27-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890227798&partnerID=MN8TOARS.
    10.1002/bmc.3004
  84. Bicker, J.; Alves, G.; Fortuna, A.; Falcão, A.. "Blood-brain barrier models and their relevance for a successful development of CNS drug delivery systems: A review". European Journal of Pharmaceutics and Biopharmaceutics 87 3 (2014): 409-432. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904264611&partnerID=MN8TOARS.
    10.1016/j.ejpb.2014.03.012
  85. Ferreira, A.; Rodrigues, M.; Oliveira, P.; Francisco, J.; Fortuna, A.; Rosado, L.; Rosado, P.; Falcão, A.; Alves, G.. "Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 971 (2014): 20-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907542842&partnerID=MN8TOARS.
    10.1016/j.jchromb.2014.09.010
  86. Fortuna, A.; Alves, G.; Serralheiro, A.; Sousa, J.; Falcão, A.. "Intranasal delivery of systemic-acting drugs: small-molecules and biomacromolecules". European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 88 1 (2014): 8-27. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934267827&partnerID=MN8TOARS.
    10.1016/j.ejpb.2014.03.004
  87. Gonçalves, Daniela; Alves, Gilberto; Fortuna, Ana; Soares-da-Silva, Patrício; Falcão, Amílcar. "An HPLC-DAD method for the simultaneous quantification of opicapone (BIA 9-1067) and its active metabolite in human plasma". The Analyst 138 8 (2013): 2463. http://dx.doi.org/10.1039/c3an36671e.
    10.1039/c3an36671e
  88. Bicker, J.; Fortuna, A.; Alves, G.; Falcão, A.. "Liquid chromatographic methods for the quantification of catecholamines and their metabolites in several biological samples - A review". Analytica Chimica Acta 768 1 (2013): 12-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875097103&partnerID=MN8TOARS.
    10.1016/j.aca.2012.12.030
  89. Serralheiro, A.; Alves, G.; Fortuna, A.; Rocha, M.; Falcão, A.. "First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plasma". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 925 (2013): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875242875&partnerID=MN8TOARS.
    10.1016/j.jchromb.2013.02.026
  90. Alves, G.; Rodrigues, M.; Fortuna, A.; Falcão, A.; Queiroz, J.. "A critical review of microextraction by packed sorbent as a sample preparation approach in drug bioanalysis". Bioanalysis 5 11 (2013): 1409-1442. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878872813&partnerID=MN8TOARS.
    10.4155/bio.13.92
  91. Sousa, J.; Alves, G.; Campos, G.; Fortuna, A.; Falcão, A.. "First liquid chromatography method for the simultaneous determination of levofloxacin, pazufloxacin, gatifloxacin, moxifloxacin and trovafloxacin in human plasma". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 930 (2013): 104-111. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878554595&partnerID=MN8TOARS.
    10.1016/j.jchromb.2013.04.036
  92. Fortuna, A.; Alves, G.; Soares-da-Silva, P.; Falcão, A.. "Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: New set of data for predictive in silico ADME models". Epilepsy Research 107 1-2 (2013): 37-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886953855&partnerID=MN8TOARS.
    10.1016/j.eplepsyres.2013.08.013
  93. Fortuna, A.; Alves, G.; Soares-da-silva, P.; Falcão, A.. "Optimization of a parallel artificial membrane permeability assay for the fast and simultaneous prediction of human intestinal absorption and plasma protein binding of drug candidates: Application to dibenz[b,f]azepine-5-carboxamide derivatives". Journal of Pharmaceutical Sciences 101 2 (2012): 530-540. http://www.scopus.com/inward/record.url?eid=2-s2.0-84455169538&partnerID=MN8TOARS.
    10.1002/jps.22796
  94. Fortuna, A.; Alves, G.; Almeida, A.; Lopes, B.; Falcão, A.; Soares-da-Silva, P.. "A chiral liquid chromatography method for the simultaneous determination of oxcarbazepine, eslicarbazepine, R-licarbazepine and other new chemical derivatives BIA 2-024, BIA 2-059 and BIA 2-265, in mouse plasma and brain". Biomedical Chromatography 26 3 (2012): 384-392. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856569184&partnerID=MN8TOARS.
    10.1002/bmc.1670
  95. Fortuna, A.; Alves, G.; Falcão, A.; Soares-Da-Silva, P.. "Evaluation of the permeability and P-glycoprotein efflux of carbamazepine and several derivatives across mouse small intestine by the Ussing chamber technique". Epilepsia 53 3 (2012): 529-538. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857546604&partnerID=MN8TOARS.
    10.1111/j.1528-1167.2012.03409.x
  96. Sousa, J.; Alves, G.; Fortuna, A.; Falcão, A.. "Analytical methods for determination of new fluoroquinolones in biological matrices and pharmaceutical formulations by liquid chromatography: A review". Analytical and Bioanalytical Chemistry 403 1 (2012): 93-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858745738&partnerID=MN8TOARS.
    10.1007/s00216-011-5706-8
  97. Sousa, J.; Alves, G.; Fortuna, A.; Pena, A.; Lino, C.; Falcão, A.. "Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma". Biomedical Chromatography 25 5 (2011): 535-541. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953682225&partnerID=MN8TOARS.
    10.1002/bmc.1480
  98. Fortuna, A.; Bicker, J.; Alves, G.; Falcão, A.; Soares-Da-Silva, P.. "A chiral HPLC-UV method for the quantification of dibenz[b,f]azepine-5- carboxamide derivatives in mouse plasma and brain tissue: Eslicarbazepine acetate, carbamazepine and main metabolites". Journal of Separation Science 34 12 (2011): 1391-1401. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959199825&partnerID=MN8TOARS.
    10.1002/jssc.201100099
  99. Fortuna, A.; Sousa, J.; Alves, G.; Falcão, A.; Soares-Da-Silva, P.. "Development and validation of an HPLC-UV method for the simultaneous quantification of carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites in human plasma". Analytical and Bioanalytical Chemistry 397 4 (2010): 1605-1615. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953806616&partnerID=MN8TOARS.
    10.1007/s00216-010-3673-0
  100. Fortuna, A.; Alves, G.; Falcão, A.; Soares-Da-Silva, P.. "Binding of licarbazepine enantiomers to mouse and human plasma proteins". Biopharmaceutics and Drug Disposition 31 5-6 (2010): 362-366. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955704455&partnerID=MN8TOARS.
    10.1002/bdd.716
  101. Alves, G.; Fortuna, A.; Sousa, J.; Direito, R.; Almeida, A.; Rocha, M.; Falcão, A.; Soares-Da-Silva, P.. "Enantioselective assay for therapeutic drug monitoring of eslicarbazepine acetate: No interference with carbamazepine and its metabolites". Therapeutic Drug Monitoring 32 4 (2010): 512-516. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955173774&partnerID=MN8TOARS.
    10.1097/FTD.0b013e3181e5c855
  102. Pires, A.; Fortuna, A.; Alves, G.; Falcão, A.. "Intranasal Drug Delivery: How, Why and What for?". Journal of Pharmacy & Pharmaceutical Sciences 12 3 (2009): 288-288. https://doi.org/10.18433%2Fj3nc79.
    10.18433/j3nc79
  103. Alves, G.; Figueiredo, I.; Castel-Branco, M.; Loureiro, A.; Fortuna, A.; Falcão, A.; Caramona, M.. "Enantioselective HPLC-UV method for determination of eslicarbazepine acetate (BIA 2-093) and its metabolites in human plasma". Biomedical Chromatography 21 11 (2007): 1127-1134. http://www.scopus.com/inward/record.url?eid=2-s2.0-36749058390&partnerID=MN8TOARS.
    10.1002/bmc.858
  104. Fortuna, A.; Alves, G.; Falcão, A.. "The importance of permeability screening in drug discovery process: PAMPA, Caco-2 and rat everted gut assays". Current Topics in Pharmacology 11 2 (2007): 63-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-56749128029&partnerID=MN8TOARS.
Preprint
  1. Silva, Ana; Silva, Sónia; Macedo, Jéssica; Moreira, Patrícia; Baptista, Diana; Bicker, Joana; Fortuna, Ana; et al. "Targeting Alzheimer's disease hallmarks with the Nrf2 activator Isoeugenol". 2023. http://dx.doi.org/10.32388/luxm7w.
    10.32388/luxm7w
Thesis / Dissertation
  1. Fortuna, Ana. "Análise farmacométrica de derivados da carbamazepina: avaliação in vitro, in vivo e in silico das suas propriedades farmacológicas". PhD, Universidade de Coimbra, 2011.

Intellectual property

Patent
  1. Maria Teresa Rosete; Fortuna, Ana; Bicker, Joana. 2022. "PCT/IB2022/052060 - SMALL MOLECULES FOR USE IN PREVENTING AND/OR TREATMENT OF NEURODEGENERATIVE DISEASES".
  2. Fortuna, Ana; Carla Vitorino; Bicker, Joana; Amílcar Falcão. 2022. "PCT/IB2022/061847 - WO/2023/105415: INTRANASAL ADMINISTRATION FOR A SUSTAINED BRAIN DELIVERY OF HIGHLY PROTEIN-BOUND DRUGS".
  3. Vitorino, Carla; Fortuna, Ana. 2020. "PCT/IB2020/061452 - WO/2021/111364A1 : Dual nanostructured lipid carrier as a multifunctional platform for brain tumor therapy".

Other

Other output
  1. Therapeutic drug monitoring of clozapine on patients with treatment resistant schizophrenia. 2021. Pereirinha Patrícia; Fortuna, Ana; Feio, J; Rocha, Marília João.
    10.1007/s11096-020-01180-4
  2. Direct oral anticoagulants (DOACs) use in patients with cardiac implantable devices and non-valvular atrial fibrillation: impact of off-label dose use in safety and efficacy outcomes. 2021. Santos Joana; António, Natália; Rocha, Marília João; Fortuna, Ana.
    10.1007/s11096-020-01180-4
  3. The impact of monitoring FVIII levels in clinical practice for hemophilia A. 2021. Pinho, Raquel; Rocha, Marília João; Fortuna, Ana.
    10.1007/s11096-020-01180-4
  4. Is the pharmacokinetics of perampanel influenced by gender and comedication in refractory epileptic patients?. 2021. Silva, Rui; Bicker, Joana; Amílcar Falcão; Fortuna, Ana.
    10.1007/s11096-020-01180-4
  5. Direct oral anticoagulants (DOACs) use in patients with cardiac implantable devices and non-valvular atrial fibrillation: the complexity of dose adjustments. 2020. Santos, Joana; António, Natália; Rocha, Marília João; Fortuna, Ana.
    10.1007/s11096-020-01180-4
  6. Pharmacokinetic data model on assessing adherence to levetiracetam. 2020. Silva, Rui; Joana Bicker; Carona, Andreia; Amílcar Falcão; Fortuna, Ana.
    10.1007/s11096-020-01180-4
  7. Avaliação da adesão terapêutica em doentes com epilepsia medicados com levetiracetam recorrendo à monitorização farmacocinética. Abstract published in Sinapse. 2020, 20 (1) supp 1: 24. 2020. Silva, Rui; Bicker, Joana; Amílcar Falcão; Fortuna, Ana. http://www.sinapse.pt/archive_detail.php?id=64.
  8. Caracterização do perfil farmacocinético do levetiracetam em doentes Portugueses com epilepsia. Abstract published in Sinapse. 2020, 20 (1) supp 1: 24. 2020. Silva Luis; Silva Rui; Amílcar Falcão; Fortuna, Ana. http://www.sinapse.pt/archive_detail.php?id=64.
  9. Monitoring lacosamide, levetiracetam, zonisamide in plasma of epileptic patients: personalizing the pharmacotherapy of levetiracetam. 2019. Gonçalves, Joana; Gouveia, Filipa; Amílcar Falcão; Fortuna, Ana.
    10.1007/s11096-018-0759-9
  10. Genetic characterization of the CYP2C9, CYP2C19, CYPD6 isoenzymes and P-glycoprotein in portuguese patients with depression. 2019. Magalhães, Paulo; Alves, Gilberto; Llerena, A.; Fortuna, Ana; Amílcar Falcão.
    10.1007/s11096-018-0759-9
  11. Evaluation of the pharmacokinetics of amikacin in neutropenic cancer patients: influence of cancer pathology and chemotherapy. 2019. Maria Tinoco; Rocha, Marília João; Amílcar Falcão; Fortuna, Ana.
    10.1007/s11096-018-0759-9
  12. Direct oral anticoagulants (DOACs) adjustment in patients with cardiac implantable devices and non-valvular atrial fibrillation: A single-centre retrospective study. 2019. Santos, Joana; António, Natália; Rocha, Marília João; Fortuna, Ana.
    10.1111/eci.13109
  13. Monitoring lacosamide, levetiracetam, zonisamide in plasma of epileptic patients: personalizing the pharmacotherapy of levetiracetam.. Abstract published in Int J Clin Pharm, 2018, doi:10.1007/s11096-018-0759-9. 2018. Gonçalves, Joana; Paulino, Jamal; Silva, Ana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana.
    10.1007/s11096-018-0759-9
  14. Application of pharmacokinetic monitoring of amikacin in its pharmacological effects.. Abstract published in Int J Clin Pharm, 2018, doi:10.1007/s11096-018-0759-9. 2018. Andrade, Ana; Rocha, Marília; Falcão, Amílcar; Fortuna, Ana.
    10.1007/s11096-018-0759-9
  15. Levetiracetam therapy individualization: predictive performance of three pharmacokinetic models.. Abstract published in Int J Clin Pharm, 2018, doi:10.1007/s11096-018-0759-9. 2018. Silva, Rui; Paulino, Jamal; Almeida, Anabela; Gonçalves, Joana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana.
    10.1007/s11096-018-0759-9
  16. Effect of kidney function on amikacin pharmacokinetics on hospitalized patients: a knowledge to improve therapy. Abstract published in Int J Clin Pharm, 2017, DOI 10.1007/s11096-017-0506-7. 2017. Rocha, Marília; Falcão, Amílcar; Fortuna, Ana.
  17. High risk of drug-induced phenoconversion and antidepressantdrug interactions at pharmacokinetic level in a naturalistic clinical setting. Abstract published in Int J Clin Pharm, 2017, DOI 10.1007/s11096-017-0506-7. 2017. Magalhães, Paulo; Alves, Gilberto; Fortuna, Ana; Llerena, A.; Falcão, Amílcar.
    10.1007/s11096-017-0506-7
  18. Phenytoin in pediatric patients: How important is the AEDs therapeutic drug monitoring?. Abstract published in Int J Clin Pharm, 2016, 38: 488. 2016. Silva, Rui; Almeida, Anabela; Rocha, Marília; Fortuna, Ana; Falcão, Amílcar.
    10.1007/s11096-015-0240-y
  19. Amikacin plasma monitoring in treating Portuguese patients infected with Acinetobacter baumannii. Abstract published in Int J Clin Pharm, 2016, 38: 595.. 2016. Oliveira, Susana; Fortuna, Ana; Rocha, Marília; Falcão, Amílcar.
    10.1007/s11096-015-0240-y
  20. Therapeutic drug monitoring of digoxin in hospitalized patients. Abstract published in Int J Clin Pharm, 2016, 38: 597.. 2016. Rocha, Marília; Fraga, Joana; Fortuna, Ana; Almeida, Anabela; Falcão, Amílcar.
    10.1007/s11096-015-0240-y
  21. Pharmacokinetics of opicapone, a novel cathecol-o-methyltransferase inhibitor, in the Wistar rat. Abstract published in Parkinsonism and Related Disorders, 2016, 22: e184. 2016. Alves, Gilberto; Gonçalves, Daniela; Fortuna, Ana; Soares-Da-Silva, Patrício; Falcão, Amílcar; Daniela Gonçalves; Gilberto Alves; et al. https://doi.org/10.1016%2Fj.parkreldis.2015.10.467.
    10.1016/j.parkreldis.2015.10.467
  22. Medication regimen complexity evaluation in a hypertensive Portuguese population. Resume published in International Journal of Clinical Pharmacy, 2015, 37: 200.. 2015. Fortuna, Ana; Tavares, Ana; Couceiro, Paula; Alves, Gilberto; Falcão, Amílcar.
    10.1007/s11096-014-0039-2
  23. A new MEPS/HPLC assay to quantify venlafaxine and its main metabolite in human plasma. Resume published in International Journal of Clinical Pharmacy, 2015, 37: 258. 2015. Fortuna, Ana; Magalhães, Paulo; Rodrigues, Marcio; Llerena, A.; Alves, Gilberto; Falcão, Amílcar.
    10.1007/s11096-014-0039-2
  24. Elucidation of the influence of dose on the pharmacokinetics of o picapone after single oral administration in rats. Abstract published in Experimental Pathology and Health Science. 2015;7(2): 37-38. 2015. Gonçalves, Daniela; Alves, Gilberto; Fortuna, Ana; Soares-Da-Silva, Patrício; Falcão, Amílcar.
    10.1007/s11096-014-0039-2
  25. Analysis of carbamazepine, lamotrigine, oxcarbazepine, phenytoin and some metabolites in mice brain tissue by high performance liquid chromatography. 2013. Serralheiro, Ana ; Alves, Gilberto; Fortuna, Ana; Amílcar Falcão.
    10.1111/eci.12088
  26. A new assay to quantify carbamazepine, lamotrigine, oxcarbazepine, phenytoin and their main metabolites in mouse liver homogenates by high performance liquid chromatography coupled with ultraviolet detection. 2013. Serralheiro, Ana ; Alves, Gilberto; Fortuna, Ana; Amílcar Falcão.
    10.1111/eci.12088
  27. Affinity to P-glycoprotein, but not to plasma proteins, determine in vivo biodisposition of eslicarbazepine and R-licarbazepine. 2013. Fortuna, Ana; Alves, Gilberto; Soares-da-Silva, Patricio; Amílcar Falcão.
    10.1111/eci.12088
  28. In vivo preclinical models for pharmacokinetic evaluation of carbamazepine and nine derivatives. 2013. Fortuna, Ana; Alves, Gilberto; Soares-da-Silva, Patricio; Amílcar Falcão.
    10.1111/eci.12088
  29. A rapid and sensitive high-performance liquid chromatographic method to quantify carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites in human plasma.. 2010. Fortuna, Ana; Alves, Gilberto; Santos L; Amílcar Falcão; Soares-da-Silva, Patricio.
    10.1111/j.1742-7843.2010.00600.x
  30. Lack of interference of carbamazepine and its metabolites in the enantioselective therapeutic drug monitoring of eslicarbazepine acetate.. 2010. Fortuna, Ana; Alves, Gilberto; Sousa, Joana; Amílcar Falcão; Soares-da-Silva, Patricio.
    10.1111/j.1742-7843.2010.00600.x
  31. Morphological evaluation of rat liver tissue after the subcutaneous injection of 1,2-dimethylhydrazine.. 2010. Fortuna, Ana; Alves, Gilberto; Amílcar Falcão; Soares-da-Silva, Patricio.
    10.1111/j.1742-7843.2010.00600.x
  32. Kidney drug exposure after multiple-dose administration of S- and R-licarbazepine to mice.. 2009. Alves, Gilberto; Nunes T; Fortuna, Ana; Serralheiro, Ana ; Rodrigues, Márcio; Amílcar Falcão; Soares-da-Silva, Patricio.
    10.1177/00912700090490091001
  33. Metabolism and liver pharmacokinetics of S- and R-licarbazepine in mice at the steady-state.. 2009. Alves, Gilberto; Nunes T; Fortuna, Ana; Serralheiro, Ana ; Rodrigues, Márcio; Amílcar Falcão; Soares-da-Silva, Patricio.
    10.1177/00912700090490091001
  34. Plasma-brain distribution of licarbazepine enantiomers in mice on steady-state conditions.. 2009. Alves, Gilberto; Nunes T; Fortuna, Ana; Serralheiro, Ana ; Rodrigues, Márcio; Amílcar Falcão; Soares-da-Silva, Patricio.
    10.1177/00912700090490091001
  35. Warfarin binding to human plasma proteins. 2008. Costa, IM; Alves, Gilberto; Fortuna, Ana; Falcão, A.; Caramona, M..
    10.1111/j.1472-8206.2008.00576.x
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024 Individualizing zonisamide therapy: development and validation of a population pharmacokinetic model Sociedade Portuguesa de Farmacologia
(Lisbon)
2023 Intranasal Irbesartan reverts cognitive decline by modulation of the PI3K/AKT pathway in mice PharmahDay 2023 | Annual Meeting of PhD Students in Pharmaceutical Sciences
2023 Population pharmacokinetic analysis of zonisamide in epileptic patients PharmahDay 2023 | Annual Meeting of PhD Students in Pharmaceutical Sciences
FFUC
2022/02/10 Pre-clinical pharmacokinetic evaluation of a skin allergen for the treatment of Alzheimer's disease LII Meeting of the Portuguese Society of Pharmacology, XXXX Meeting of Clinical Pharmacology and XXI Meeting of Toxicology
2022/02/10 Drug-drug pharmacokinetic interactions between carbamazepine and new antiepileptic drugs LII Meeting of the Portuguese Society of Pharmacology, XXXX Meeting of Clinical Pharmacology and XXI Meeting of Toxicology
(Porto, Portugal)
2022/02/10 Therapeutic drug monitoring of clozapine on patients with refractory schizophrenia 52º reunião da Sociedade Portuguesa de Farmacologia
2021/12 Nasal-PAMPA: a novel in vitro tool for prediction of intranasal drug permeability Drug Delivery to the Lungs 2021
2021/11 Spray-Dried Amorphous Solid Dispersions for Nasal Delivery: Development, Characterization and Performance AIChE Annual Meeting 2021
2021/02/19 QUANTIFICATION OF ANTIEPILEPTIC DRUGS IN HUMAN SALIVA BY HPLC-DAD AS A NEW TOOL FOR THERAPEUTIC DRUG MONITORING Sociedade Portuguesa de Farmacologia
(Portugal)
2021/02/19 NOSE-TO-BRAIN DELIVERY OF PERAMPANEL: A PROMISING THERAPEUTIC APPROACH FOR EPILEPSY Sociedade Portuguesa de Farmacologia
(Portugal)
2021/02/19 ASSESSMENT OF EPILEPTIC PATIENTS COMPLIANCE TO LEVETIRACETAM THERAPY THROUGH A PHARMACOKINETIC APROACH Sociedade Portuguesa de Farmacologia
(Portugal)
2021/02/19 INTRANASAL CO-ADMINISTRATION OF ESCITALOPRAM AND PAROXETINE IN MICE Sociedade Portuguesa de Farmacologia
(Portugal)
2021/02/17 IMPACT OF OFF-LABEL DOACS DOSE IN PATIENTS WITH CARDIAC IMPLANTABLE ELECTRONIC DEVICES AND NON-VALVULAR ATRIAL FIBRILLATION ON SAFETY AND EFFICACY OUTCOMES: A REAL-WORLD STUDY Sociedade Portuguesa de Farmacologia
(Portugal)
2020/02 ADJUSTMENT OF DIRECT ORAL ANTICOAGULANTS IN PATIENTS WITH CARDIAC IMPLANTABLE DEVICES AND NON-VALVULAR ATRIAL FIBRILLATION: INFLUENCE ON THE OUTCOMES SPF Meeting 2020 - Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2020/02 PHARMACOKINETICS OF ZONISAMIDE AFTER INTRANASAL ADMINISTRATION TO MICE SPF Meeting 2020 - Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2020/02 UNDERSTANDING NOSE-TO-BRAIN ANTIDEPRESSANT DELIVERY: A COMPREHENSIVE IN VITRO/IN VIVO APPROACH SPF Meeting 2020 - Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2020/02 INFLUENCE OF CO-MEDICATION ON LEVETIRACETAM PHARMACOKINETICS IN EPILEPTIC PATIENTS SPF Meeting 2020 - Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2020/02 HEPA-RG CELLS AS A PROMISING IN VITRO MODEL TO STUDY THE METABOLIC KINETICS OF PERAMPANEL, RUFINAMIDE AND STIRIPENTOL AND TO PREDICT DRUG INTERACTIONS MEDIATED BY METABOLIC INDUCTION Meeting 2020 - Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2020/02 HIGH PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED TO DIODE ARRAY TO SUPPORT PHARMACOKINETIC MONITORING OF APIXABAN, DABIGATRAN, EDOXABAN AND RIVAROXABAN SPF Meeting 2020 - Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2019/12 DESIGNING LIPID NANOPARTICLES FOR INTRANASAL DELIVERY OF ANTIDEPRESSANTS Drug Delivery to the Lungs (DDL 2019)
(Edinburgh, United Kingdom)
2019/02/08 EXTENT OF BRAIN EXPOSURE OF CATECHOLO-METHYLTRANSFERASE INHIBITORS: IN VIVO PHARMACOKINETIC STUDIES SPF Meeting 2019
2019/02/08 INDIVIDUALIZING PHARMACOTHERAPY OF LEVETIRACETAM: PREDICTIVE PERFORMANCE OF THREE PHARMACOKINETIC MODELS SPF Meeting 2019
(Porto, Portugal)
2019/02/08 INTRANASAL ADMINISTRATION OF LEVETIRACETAM IN MICE: IS IT A PROMISING NOSE-TO-BRAIN STRATEGY? SPF Meeting 2019
(Porto, Portugal)
2019/02/08 DEVELOPMENT AND VALIDATION OF THE FIRST HPLC-DAD METHOD FOR RUFINAMIDE QUANTIFICATION IN MOUSE PLASMA AND TISSUES WITH FOCUS ON FUTURE PHARMACOKINETIC STUDIES SPF Meeting 2019
(Porto, Portugal)
2018/03/10 INDIVIDUALIZAÇÃO POSOLÓGICA DE LEVETIRACETAM: AVALIAÇÃO DA CAPACIDADE PREDITIVA DE TRÊS MODELOS FARMACOCINÉTICOS 30 Encontro Nacional de Epileptologia
(Coimbra, Portugal)
2018/02/17 DEVELOPMENT OF A SCREENING METHOD FOR THE EVALUATION OF P-GLYCOPROTEIN MEDIATED EFFLUX AT THE BLOOD-BRAIN BARRIER Mini Symposium on P-glycoprotein
(Coimbra, Portugal)
2018/02/06 EVALUATION OF PHARMACOKINETICS OF AMIKACIN IN NEUTROPENIC CANCER PATIENTS. XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia Clínica; XVII Reunião de Toxicologia
2017/02 PHARMACOKINETICS OF OPICAPONE IN RAT AND ITS EFFECT ON CATECHOL- O-METHYLTRANSFERASE ACTIVITY AFTER SINGLE AND MULTIPLE ORAL DOSES XLVII Reunião Anua l de Sociedade Portuguesa de Farmacologia
2017 INTERACTION OF COMT INHIBITORS WITH P-GLYCOPROTEIN AND BREAS T CANCER RESISTANCE PROTEIN: A FOCUS ON THE BLOOD-BRAIN-BARRIER XLVII Reunião Anual de Sociedade Portuguesa de Farmacologia
2015/02 INTRANASAL ADMINISTRATION OF LAMOTRIGINE IN MICE: PHARMACOKINETICS AND BRAIN BIODISTRIBUTION. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia
2015 QUANTIFICATION OF OPICAPONE AND ITS ACTIVE METABOLITE IN RAT MATRICE S BY A NEW HPLC-DAD METHOD. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia
2015 A NOVEL PAMPA MODEL TO PREDICT THE BLOOD -BRAIN BARRIER PERMEABILITY OF NEW DRUG CANDIDATES. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia
2015 A VIA INTRANASAL COMO ESTRATÉGIA ALTERNATIVA P ROMISSORA PARA A ADMINISTRAÇÃO DE FÁRMACOS ANTIEPILÉTICOS - AVALIAÇÃO DO POTENCIAL DE APLICAÇÃO À LAMOTRIGINA. 27º Encontro Nacional de Epileptologia
2014/02 SYSTEMIC AND DIRECT NOSE-TO-BRAIN DELIVERY OF CARBAMAZEPINE FOLLOWING INTRANASAL ADMINISTRATION TO MICE XLIIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXII Reunião de Farmacologia Clínica; XIII Reunião de Toxicologia
(Coimbra, Portugal)
2014/02 IN VITRO IDENTIFICATION OF ESSENTIAL OILS AS P-GLYCOPROTEIN INHIBITORS: A SCREENING STRATEGY USING CACO-2 CELLS XLIIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXII Reunião de Farmacologia Clínica; X III Reunião de Toxicologia.
(Portugal)
2014/02 MEPS/HPLC–DAD METHOD FOR THE SIMULTANEOUS QUANTIFICATION OF SEVERAL ANTIEPILEPTIC DRUGS AND THEIR ACTIVE METABOLITES IN HUMAN PLASMA. XLIIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXII Reunião de Farmacologia Clínica; XIII Reunião de Toxicologia
2013/12 QUANTITATIVE ANALYSIS OF OPICAPONE AND ITS ACTIVE METABOLITE IN RA T MATRICES BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED TO A DIODE ARRAY DETECTOR. 8º Encontro Nacional de Cromatografia.
(Covilhã, Portugal)
2013/12 PHARMACOKINETICS AND BRAIN BIODISTRIBUTION OF CARBAMAZEPINE AFTER INTRANASAL ADMINISTRATION TO MICE. XI Annual CNC Meeting – Center for Neuroscience and Cell Biology.
(Coimbra, Portugal)
2013/02 PLASMA AND BRAIN PHARMACOKINETICS OF NINE CARBAMAZEPINE DERIVATIVES ORALLY ADMINISTERED TO MICE: IMPLICATIONS FOR SELECTION OF DRUG CANDIDATES XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXXI Reunião de Farmacologia Clínica; XII Reunião de Toxicologia
(Porto, Portugal)
2013 HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY FOR QUANTIFICATION OF LEVOFLOXACIN, PAZUFLOXACIN, GATIFLOXACIN, MOXIFLOXACIN AND TROVAFLOXACIN IN HUMAN PLASMA. XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXI Reunião de Farmacologia Clínica; XII Reunião de Toxicologia
(Porto, Portugal)
2012/03/09 AVALIAÇÃO FARMACOMÉTRICA IN SILICO, IN VITRO E IN VIVO DA CARBAMAZEPINA E ANÁLOGOS ESTRUTURAIS 24º Encontro Nacional de Epileptologia
(Coimbra, Portugal)
2012/02 IN VITRO EVALUATION OF INTESTINAL PERMEABILITY AND P -GLYCOPROTEIN EFFLUX OF CARBAMAZEPINE AND DERIVATIVES. XLII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXX Reunião de Farmacologia Clínica; XI Reunião de Toxicologia
(lisbon, Portugal)
2011/02 A FAST ISOCRATIC LIQUID CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS DETERMINATION OF NORFLOXACIN, CIPROFLOXACIN AND LOMEFLOXACIN IN HUMAN PLASMA XLI Reunião da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia.
(Coimbra, Portugal)
2011/02 A NEW HPLC METHOD FOR THE DETERMINATION OF SIX ANTIEPILEPTIC DRUGS AND THREE OF THEIR MAIN METABOLITES IN HUMAN PLASMA XLI Reunião da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia.
(Coimbra, Portugal)
2011/02 A CHIRAL HPLC-UV METHOD FOR THE SIMULTANEOUS Q UANTIFICATION OF ESLICARBAZEPINE ACETATE, CARBAMAZEPINE AND METABOLITES IN MOUSE PLASMA AND BRAIN XLI Reunião da Sociedade Portuguesa d e Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia.
(Coimbra, Portugal)
2010/12/21 DEVELOPMENT OF IN VITRO MODELS FOR PREDICTION OF HUMAN DRUG ABSORPTION VIII Encontro Anual do Centro de Neurociências e Biologia Celular & Reunião Anual do Programa Doutoral em Biologia Experimental e Biomedicina.
(Coimbra, Portugal)
2009/12/04 DEVELOPMENT OF A PARALLEL ARTIFICIAL MEMBRANE PERMEABILITY ASSAY FOR PREDICTION OF HUMAN ABSORPTION XL Reunião da Socied ade Portuguesa de Farmacologia, XXVIII Reunião da Farmacologia Clínica e IX Reunião de Toxicologia
(Porto, Portugal)
2009/12/04 A NOVEL HPLC METHOD TO QUANTIFY CARBAMAZEPINE, OXCARBAZEPINE, ESLICARBAZEPINE ACETATE AND MAIN METABOLITES IN HUMAN PLASMA. XL Reunião da Sociedade Portuguesa de Farmacologia XXVIII Reunião de Farmacologia Clínica e IX Reunião d e Toxicologia
(Porto, Portugal)
2008/12/05 PLASMA PROTEIN BINDING OF LICARBAZEPINE ENANTIOMERS IN HUMAN AND MOUSE SPECIES XXXIX Reunião Anual da Sociedade Portuguesa de Farmacologia, XXVI Reunião de Farmacologia Clínica e VIII Reunião de Toxicologia
(Lisbon, Portugal)
2008/12/05 LACK OF INTERFERENCE OF CARBAMAZEPINE AND ITS METABOLITES IN THE THERAPEUTIC DRUG MONITORING OF OXCARBAZEPINE XXXIX Reunião da Sociedade Portuguesa de Farmacologia, XXVI Reunião de Farmacologia Clínica e VIII Reunião de Toxicologia.
(Lisbon, Portugal)
2006 A CHIRAL HPLC-UV-SPE ASSAY FOR ESLICARBAZEPINE ACETATE (BIA 2-093) AND ITS METABOLITES DETERMINATION IN BIOLOGICAL SAMPLES XXXVII Reunião da Sociedade Portuguesa de Farmacologia, XXIV Reunião de Farmacologia Clínica e VI Reunião de Toxicologia.

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/09 - Current Avaliação do Impacto da Monitorização Terapêutica de Antiepiléticos na Tomada de Decisão Clínica e nos Outcomes Clínicos
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023/09 - Current Monitorização terapêutica e desenvolvimento de modelos farmacocinéticos populacionais para uma estratégia terapêutica racional com infliximab e adalimumab em doentes com DII
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023/09 - Current Therapeutic use of psychedelics to improve mental well-being.
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 - Current Monitorização Terapêutica do Infliximab na Doença Inflamatória Intestinal
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/10/01 - Current PhD Thesis "Strive against Alzheimer's disease through the modulation of depressive state and the use of cannabinoids" (ref. 2021.06135.BD)
Supervisor
2021/09/01 - Current PhD thesis "Evaluation of intranasal delivery of cannabinoids and their potential for the treatment of epilepsy" (Ref. 2021.06125.BD)
Supervisor
 PhD
2019/10 - Current Monitorização farmacocinética de antiepiléticos de nova geração na prática clínica (PhD)
Co-supervisor
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/03 - 2034/01 Amorphous solid dispersions for nasal delivery: bridging particle engineering with in vitro and in vivo performance (PhD, PD/BDE/150298/2019)
Supervisor
Fundação para a Ciência e a Tecnologia, Portugal

Universidade de Coimbra Faculdade de Farmácia, Portugal

Hovione, Portugal
2020/11 - 2024/09 Targeting the brain renin-angiotensin system by nose-to-brain delivery for prevention and treatment of Alzheimer's disease (PhD; 2020.04442.BD)
Supervisor
Fundação para a Ciência e a Tecnologia, Portugal

Universidade de Coimbra Faculdade de Farmácia, Portugal

Universitat de Barcelona Facultat de Farmacia, Spain
2020/05 - 2024/06 Chronopharmacokinetics and chronopharmacodynamics of intranasal antidepressant drugs (PhD, PD/BDE/150685/2020)
Supervisor
Fundação para a Ciência e a Tecnologia, Portugal

Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - 2024/02 Biohybrid Nanosystems for Drug and Nucleic Acid co-Delivery in Glioblastoma (SFRH/BD/149138/2019)
Co-supervisor
 PhD (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09/01 - 2024 Permeability across distinct cell monolayers as models for BBB: quantitative evaluation of the different permeation routes (PhD, SFRH/BD/138873/2018)
Co-supervisor
Universidade de Coimbra, Portugal
2022/09 - 2023/10 Pharmacokinetic evaluation of a nonsteroidal anti-inflammatory drug after intranasal administration to mice
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/09 - 2023/02 Farmacocinética Populacional da Carbamazepina e da Carbamazepina-10,11-epóxido em Doentes com Epilepsia Refratária
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 - 2023 Intranasal Administration of Ketamine and derivates to Mice: Assessment of Antidepressant Effect and Neurotransmitter Levels in the Brain
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - 2023 Monitorização farmacocinética da vancomicina
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020 - 2021/12 Pharmacogenetic approach for epilepsy treatment with zonisamide - a pilot study (Master)
Supervisor
 Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
2020 - 2021/12 Pharmacokinetics analysis of clotting factors: identification of factors of variability (Master)
Supervisor
 Master in Applied Pharmacology
2020 - 2021/12 Nose-to-brain sertralin delivery: are blood-brain-barrier and breast cancer resistant protein avoided? (Master)
Supervisor
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/09 - 2021/12 Estudo de concentrações séricas de Perampanel e caracterização do seu perfil cinético (Master)
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2019/09 - 2021/12 Monitorização Farmacocinética da Clozapina e Norclozapina em doentes com Esquizofrenia Farmacoresistente (Master)
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2016/10 - 2021/04 Intranasal administration of new generation antiepileptic drugs: its pharmacokinetic and pharmacodynamic evaluation and influence on multi-drug transporter hypothesis underlying the pharmacoresistant epilepsy (PhD)
Supervisor
 Doutoramento em Ciências Farmacêuticas (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/09 - 2020/12 Development of an analytical technique for the quantification of anti-epileptic drugs in saliva as a new tool for therapeutic monitoring of epileptic patients (Master)
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/09 - 2020/11 Influência da complexidade terapêutica na adesão à terapêutica com Anticoagulantes Orais Diretos
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09 - 2019/09 CARACTERIZAÇÃO DO PERFIL FARMACOCINÉTICO DO LEVETIRACETAM NA POPULAÇÃO PORTUGUESA (Master)
Supervisor
 Mestrado em Farmaoclogia Aplicada (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09 - 2019/09 A realidade dos ensaios clínicos em pediatria: uma perspetiva farmacocinética
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09 - 2019/07 Identificação de fatores de risco que alteram farmacocinética e segurança de novos anticoagulantes orais diretos. (Master)
Supervisor
 Mestrado em Farmaoclogia Aplicada
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09 - 2019/07 Development of an Analytical Technique for Plasma Concentration Monitoring of Perampanel, Lamotrigine and Retigabine in Drug-Resistant Epileptic Patients (Master)
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/09 - 2018/07 Monitorização plasmática e farmacocinética de novos fármacos antiepiléticos em doentes com epilepsia refratária: foco no levetiracetam (Master)
Supervisor
 Mestrado de Farmacologia Aplicada (Master)
Universidade de Coimbra, Portugal
2016/09 - 2018/01 Impacto da Aplicação da Monitorização Farmacocinética Clínica na Utilização da Amicacina
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra, Portugal
2016 - 2017/09 Monitorização Farmacocinética da Amicacina em Doentes Oncológicos
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra, Portugal
2013 - 2015/01 Impacto da monitorização de antibióticos no tratamento de infeções nosocomiais por Acinetobacter baumannii nos HUC-CHUC, EPE.
Supervisor
 Mestrado em Farmacologia APlicada
Universidade de Coimbra, Portugal
2014 - 2015 Influência da Função Renal na Otimização da Terapêutica da Amicacina.
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra, Portugal
2014 - 2015 Desenvolvimento de uma técnica de HPLC para a quantificação de Colistina em plasma humano e a sua monitorização sérica em doentes internados no CHUC.
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra, Portugal
2012 - 2013 Barreiras e Limitações de uma Unidade de Farmacocinética Clínica. Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra, Portugal
2011 - 2012 Medicamentos Potencialmente Inapropriados em Idosos – a realidade de um serviço de Medicina
Supervisor
 Mestrado em Farmacologia Aplicada (Master)
Universidade de Coimbra, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/03/03 - 2023/03/03 I Fórum em Saúde: O efeito das alterações climáticas na Saúde (2023/03/03 - 2023/03/03)
Symposium (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/02/05 - 2020/02/07 SPF Meeting 2020 - Sociedade Portuguesa de Farmacologia (2020/02/05 - 2020/02/07)
Congress (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Farmácia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2022/10/07 - Current RNA- based Medicines for Unmet Medical Needs
International Pharmaceutical Federation, Netherlands
2022/10/05 - Current Precision Medicine: Where are the Technology Heading?
Symposium
International Pharmaceutical Federation, Netherlands
2022/09/16 - Current Mostra Tecnológica de Saúde: Inovação em Saúde
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/09/05 - Current 3D Printing in Pharmaceutics and Personalized Medicine
Seminar
Pharmaceutics International Inc, United States
2022/07 - Current 1st UC Meeting of Doctoral Schools
Universidade de Coimbra, Portugal
2022/09/27 - 2023/10/01 Cold Spring Harbor Laboratory Conference on Mechanisms of Aging
Cold Spring Harbor Laboratory, United States
2023/03/03 - 2023/03/03 I Fórum em Saúde: O efeito das alterações climáticas na Saúde
Conference
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023/02/01 - 2023/02/03 53ª Reunião da Sociedade Portuguesa de Farmacologia, 41ª Reunião de Farmacologia Clínica e 22ª Reunião de Toxicologia
2022/11/10 - 2022/11/12 XV CONGRESSO NACIONAL DA APFH
Congress
2021/02/17 - 2021/02/19 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20.ª Reunião de Toxicologia.
2020/02/05 - 2020/02/07 50.ª Reunião da Sociedade Portuguesa de Farmacologia, 38.ª Reunião de Farmacologia Clínica e 19.ª Reunião de Toxicologia.
Congress
2019 - 2019 XLVIX Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia Clínica e XVIII Reunião de Toxicologia
Congress
2018/02 - 2018/02 30º Encontro Nacional de Epileptologia,
Congress
2018/02 - 2018/02 XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia Clínica e XVII Reunião de Toxicologia
Congress
2018 - 2018 mini Symposium on P-glycoprotein
Symposium
2018 - 2018 47th ESPC Symposium on Clinical Pharmacy: Personalized Pharmacy Care
Symposium
2018 - 2018 III Simpósio Nacional de ORBEAS
Symposium
2017/02 - 2017/02 XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXVI Reunião Anual de Farmacologia Clínica; XVII Reunião Anual de Toxicologia.
Congress
2015/02 - 2015/02 XLV Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXIII Reunião de Farmacologia Clínica e XIV Reunião de Toxicologia.
Congress
2014/02 - 2014/02 XLIIII Reunião Anual da Socied ade Portuguesa de Farmacologia, XXXII Reunião de Farmacologia Clínica; XIII Reunião de Toxicologia.
Congress
2013/02 - 2013/02 XLIII Reunião Anual da Socieda de Portuguesa de Farmacologia; XXXI Reunião de Farmacologia Clínica; XII Reunião de Toxicologia
Congress
2012/03 - 2012/03 24º Encontro Nacional de Epileptologia.
Congress
2012/02 - 2012/02 XLII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXX Reunião de Farmacologia Clínica; XI Reunião de Toxicologia
Congress
2011/12 - 2011/12 XLI Reunião da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia
Congress
2010/12 - 2010/12 VIII Encontro Anual do Centro de Neurociências e Biologia Celular & Reunião Anual do Programa Doutoral em Biologia Experimental e Biomedicina
Congress
2009/12 - 2009/12 XL Reunião da Socied ade Portuguesa de Farmacologia, XXVIII Reunião da Farmacologia Clínica e IX Reunião de Toxicologia
Congress
2008/12 - 2008/12 XXXIX Reunião Anual da Sociedade Portuguesa de Farmacologia, XXVI Reunião de Farmacologia Clínica e VIII Reunião de Toxicologia
Congress
2006/12 - 2006/12 XXXVII Reunião da Sociedade Portuguesa de Farmacologia, XXIV Reunião de Farmacologia Clínica e VI Reunião de Toxicologia
Congress

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/01 Amorphous solid dispersions for nasal delivery: bridging particle engineering with in vitro and in vivo performance
Supervisor
 Patrícia Henriques (PhD)
2024/01 Pharmacometric Evaluation of the Intranasal Administration of New Antiepileptic Drugs Loaded in Lipidic Nanosystems: Focus on Perampanel and Stiripentol
(Thesis) Arguer
 Sara Alexandra Meirinho (PhD)
2023/05 ROLE OF OSTEOSARCOMA-DERIVED SECRETOME AND EXOSOMES IN LUNG METASTATIC ORGANOTROPISM: FROM PREMETASTATIC NICHE FORMATION TO MOLECULAR IMAGING
Thesis Member
 Sara Filipa Fernandes de Almeida (PhD)
Universidade de Coimbra, Portugal
2023 Development of New Drug Combinations for Cancer Treatment
(Thesis) Arguer
 Diana Sousa Duarte (PhD)
Universidade do Porto, Portugal
2022/02/23 Nose-to-brain delivery of lacosamide, levetiracetam and zonisamide and the impact of BCRP efflux: an in vitro/in vivo approach
Supervisor
 Joana Carrapiço Gonçalves (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 Improving the Treatment of Neurodegenerative Disorders by means of Lipid Nanoparticles Formulations for Intranasal/ Direct Nose-to-Brain Administration
(Thesis) Arguer
 Sara Maria Pereira Alves Cunha (PhD)
Universidade do Porto, Portugal
2021/12 Pharmacokinetic analysis of clotting factors: identifying individual characteristics of variability
Supervisor
 Raquel Moreira de Pinho (Master)
2021/12 Monitorizaçãofarmacocinética da clozapina em doentes com esquizofrenia resistente ao tratamento
Supervisor
 Patrícia Raquel Ribeiro Pereirinha (Master)
2021/12 Antidepressant drug administration to mice through intranasal, intravenous and oral routes: from bioanalysis to pharmacokinetics
Supervisor
 Catarina Guerreiro Mestre (Master)
2021/11/05 Patogénese e Estratégias Terapêuticas no Tratamento da Psoríase
(Thesis) Main arguer
 Inês Formiga Santos (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/10/12 Cannabinoid-based therapies for the treatment of Central Nervous System related disorders
(Thesis) Main arguer
 Fátima Catarina Trinco (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/09 Pharmacokinetic Monitorization of Monoclonal antibodies: example of infliximab in inflammatory bowel diseases"
Supervisor
 Elsa Mariana Veiga Morgado (Master)
2021/09 Cannabinoid-based therapies for the treatment of central nervous system related diseases
(Thesis) Main arguer
 Fátima Catarina Oliveira Trinco (Master)
2021/09 Patogénese e estratégias terapêuticas no tratamento da Psoríase
(Thesis) Main arguer
 Inês Formiga Santos (Master)
2020/10/11 A realidade dos ensaios clínicos em pediatria: uma perspetiva farmacocinética
Supervisor
 Marta Roque dos Santos (Master)
2020/09/15 Lithium as a mood stabilizer in Bipolar Disease.
Supervisor
 Ana Sara Rocha Ramos Ferreira (Master)
2020/07/28 Fumarato de dimetilo, da Esclerose Múltipla às doenças neurodegenerativas.
(Thesis) Arguer
 Sara Gabriela Costa Marques (Master)
2020/07/23 Cystic fibrosis: physiopathology and the latest pharmacological treatments
Supervisor
 Carla Alexandra Almeida Fonseca (Master)
2020/07/23 Pharmacometabolomics and therapeutic drug monitoring in neuropsychiatric drugs.
Supervisor
 Maria Teresa de Alcântara Dias Antunes (Master)
2020/01/08 Pharmacometric evaluation of the clinical impact of genetic polymorphisms of the cytochrome P450 and P-glycoprotein in the pharmacokinetics and pharmacodynamics of antidepressant drugs: fluoxetine, paroxetine and venlafaxine
(Thesis) Arguer
 Paulo Ricardo Machado Magalhães (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/10/16 Improving antibiotic prescribing in primary care
(Thesis) Arguer
 António Duarte Teixeira Afonso Rodrigues (PhD)
2019/09/27 Caracterização do perfil farmacocinético do levetriacetam na população Portuguesa
Supervisor
 Luís Filipe Bastos e Marques da Silva (Master)
2019/07/15 Uso de antidepressivos por crianças e adolescentes e o risco de comportamentos suicidas.
(Thesis) Main arguer
 Cíntia Souto Lopes (Master)
2019/03/08 Nonclinical assessment of the potential for herb-drug interactions between herbal extracts present in weight loss supplements and lamotrigine
(Thesis) Main arguer
 Sandra Cristina do Espírito Santo Ventura (PhD)
Universidade da Beira Interior, Portugal
2019/02/12 Bioanalytical tools for unraveling part of the puzzle of the biochemical phenomena in epilepsy: neuromediators and antiepileptic drugs
(Thesis) Arguer
 Beatriz Marques da Fonseca (PhD)
Universidade da Beira Interior, Portugal
2019 Farmacologia, dieta e suplementação na perturbação de hiperatividade com défice de atenção: o que sabemos até agora e perspetivas futuras
(Thesis) Main arguer
 Ana Margarida Diogo Sequeira (Master)
2018/09/28 Polimiosite: Fisiopatologia e Terapêutica
(Thesis) Main arguer
 André Oliveira Alves (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09/24 Myasthenia Gravis: revision and new therapeutic strategies
(Thesis) Main arguer
 Bernardo José de Albuquerque Lima (Master)
2018/09/12 Importância dos Transportadores no controlo da exposição fetal a xenobioticos.
(Thesis) Main arguer
 Diana Raquel dos Santos Godinho (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09/10 Papel da vitamina D na performance cognitiva
(Thesis) Main arguer
 Ana Rita Gonçalves Abreu (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/02/23 Coadministration of antiepileptic drugs and P-glycoprotein inhibítors of flavonoid-type: a strategy to overcome the drug resistance in epilepsy
(Thesis) Arguer
 Ana Filipa Ferreira (PhD)
Universidade da Beira Interior, Portugal
2018/02/08 Development of new antiepileptic drug candidates: a set of lamotrigine-related compounds
(Thesis) Arguer
 Mariana Matias (PhD)
Universidade da Beira Interior, Portugal
2018/01/04 Avaliação farmacológica da administração nasal de fluoroquinolonas e seu potencial no tratamento tópico da rinossinusite crónica
(Thesis) Arguer
 Joana Maria Almeida e Sousa (PhD)
Universidade de Coimbra, Portugal
2017/09/07 Computer aided drug design and its application on blood-brain barrier permeation
(Thesis) Main arguer
 Henrique Miguel Marques Bentes (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/07/21 Avaliação farmacométrica de um novo inibidor da catecol-O-metiltransferase: BIA 9-1067 [(2,5-dicloro-3-(5-(3,4-dihidroxi-5-nitrofenil)-1,2,4-oxadiazol-3-il)-4,6-dimetilpiridina 1-oxido)
(Thesis) Arguer
 Daniela Gonçalves (PhD)
Universidade de Coimbra, Portugal
2017/07 Development of a blood-brain barrier perfusion model: identification of Molecules with cerebral permeability
(Thesis) Main arguer
 Ricardo Filipe Serrano Costa (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/07/13 Resveratrol: do laboratório à clínica
(Thesis) Main arguer
 Ana Margarida Carmo Viola (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/01/07 Intranasal Delivery of Antiepileptic Drugs: Non-clinical Evaluation of Pharmacokinetics and Brain Biodistribution
(Thesis) Arguer
 Ana Isabel Azevedo Serralheiro (PhD)
Universidade de Coimbra, Portugal
2015/05/14 Necrólise epidérmica tóxica induzida por fármacos
(Thesis) Main arguer
 Benedita Pires (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015/05/14 Análise do Folheto Informativo de MNSRM para afecções comuns do trato GI
(Thesis) Main arguer
 Nadine Mota (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014/07 Caracterização da utilização de medicamentos em idosos residentes em lares através da aplicação dos critérios de Beers
(Thesis) Main arguer
 Sara Catarina dos Santos (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014/07 Caracterização do perfil de consumo de ansiolíticos, sedativos e hipnóticos na Beira Interior
(Thesis) Main arguer
 André Agostinho (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013/07/16 Hepatotoxicidade mediada por fármacos e outros produtos medicinais: Um estudo retrospetivo
(Thesis) Main arguer
 Mafalda Teresa Rocha Faria (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013/07/16 Predição in silico da permeabilidade intrínseca determinada pelo ensaio in vitro Double-Sink PAMPA utilizando redes neuronais artificiais
(Thesis) Main arguer
 Gonçalo Filipe Relvas Campos (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012/09 Estudo de suscetibilidade a antibióticos de Enterobacterias isoladas nos hospitais da Universidade de Coimbra
(Thesis) Main arguer
 Eloisa Carolina Silva Pina (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2012/07/12 Avaliação da interação de fármacos com a amiodarona em células HepaRG
(Thesis) Main arguer
 Ana Filipa da Silva Ferreira (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012/07/12 Análise da Monitorização Farmacocinética da Gentamicina nos Serviços Farmacêuticos do CHCB
(Thesis) Main arguer
 Paulo Ricardo Machado Magalhães (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - Current Drug Monitoring in Personalized Pharmacotherapy Integrated Master in Pharmaceutical Sciences Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/09 - Current Screening Farmacológico, Licenciatura em Farmácia Biomédica (FFUC) (Licenciatura) Universidade de Coimbra, Portugal
2016 - Current Pharmacometrics, Doutoramento em Ciencias Farmacêuticas (FFUC) (Doutoramento) Universidade de Coimbra, Portugal
2014 - Current Farmacocinética Clínica, Mestrado em Farmacologia Aplicada (FFUC) (Mestrado) Universidade de Coimbra, Portugal
2011 - Current Farmacocinética Clínica de Licenciatura em Farmácia Biomédica (FFUC) (Licenciatura) Universidade de Coimbra, Portugal
2011 - Current Farmacologia Geral, Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Coimbra, Portugal
2011 - Current Farmacologia I, Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Coimbra, Portugal
2011 - Current Anatomofisiologia Humana II, Mestrado Integrado em Ciências Farmacêuticas (FFUC) (Mestrado integrado) Universidade de Coimbra, Portugal
2017 - 2019 Desenvolvimento Pré-clínico do Medicamento, Licenciatura em Farmácia Biomédica (FFUC) (Licenciatura) Universidade de Coimbra, Portugal
2011 - 2018 Anatomofisiologia Humana I, Mestrado Integrado em Ciências Farmacêuticas (FFUC) (Mestrado integrado)
2013 - 2013 Collaboration within the discipline: Química Terapêutica Avançada, Mestrado em Design e Desenvolvimento de Fármacos (FFUC) (Mestrado)
2011 - 2013 Farmacologia II, Mestrado Integrado em Ciências Farmacêuticas (FFUC) (Mestrado integrado)

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2023/03 Interview: Novas análises ajudam os médicos a prescrever canábis Jornal de Notícias
2022 Interview “Novas abordagens terapêuticas para a Depressão, Doença de Alzheimer e Epilepsia” Diário As Beiras
2022 Manual das Saídas Profissionais, do Núcleo de Estudantes de Farmácia da Associação Académica de Coimbra
2019/03 Ana Fortuna, a teacher & investigator O Pilão (Jornal da FFUC)
Distinctions

Award

2023 World's Top 2% Scientist 2023
2023 Prémio de Inovação J. Norberto Pires
Universidade de Coimbra, Portugal
2023 Prémio Melhor Poster do 2º Encontro de Estudantes de Doutoramento em Ciências Farmacêuticas
2022 Prémio Melhor Poster do 1st Advances in Polymeric Micelles for Therapeutic Applications
Congress Organization 1st Advances in Polymeric Micelles for Therapeutic Applications, Portugal
2022 Paper published in Top 5% na área Geriatrics & Gerontology
2022 World's Top 2% Scientist 2022
2021 Best ePoster of the 33rd National Meeting of Epileptology
2018 Prémio Melhor Poster do 30º Congresso Nacional em Epileptologia
2015 Prémio Anual da Liga Portuguesa contra a Epilepsia
2015 Prémio Melhor Poster APFH
2012 Prémio Anual da Liga Portuguesa contra a Epilepsia
2006 Bolsa de Estudo por Mérito - 3% Best students from UC
Universidade de Coimbra, Portugal
2006 Prémio Sociedade Farmacêutica Lusitana
Ordem dos Farmaceuticos, Portugal
2005 Bolsa de Estudo por Mérito - 3% Best students from UC

Title

2021 European Certified Pharmacologist (EuCP)
Sociedade Portuguesa de Farmacologia, Portugal
2015 Investigator/Coordinator for scientific experimentation involving animals
Direcção-Geral de Alimentação e Veterinária, Portugal