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Nísia Martins is enrolled in PhD Degree in Biomedical Sciences at Algarve Biomedical Center Research Institute (ABC-RI), granted by Fundação para a Ciência e Tecnologia (FCT). The PhD project relies on how the temporal control of cell differentiation is achieved, specifically at the level of epigenome dynamics during early stages of development. Nísia concluded a Master's Degree in Molecular Genetics and Biomedicine in January 2022 at NOVA School of Science and Technology - FCT NOVA, where she previously obtained a Bachelor's degree in Cell and Molecular Biology in June 2019. She also concluded a Post-Graduate Course on Laboratory Animal Science in 2021/09/24 by Faculty of Pharmacy, University of Lisbon. She has great command over a highly diverse range of laboratory equipment and techniques (namely electroporation, in situ hybridization, RT-qPCR, immunohistochemistry, maintenance of tissue and organs from cellular and animal models and protein/DNA/RNA quantification in tissue). She also has knowledge of standard Bioinformatic tools and analysis of experimental data. Nísia also has concluded of the 5th grade of Guitar, Orquestra and Musical Education. Works in the area of Natural Sciences with emphasis on Biological Sciences. Her research fields of interest include Developmental Biology and Regenerative Medicine.
Identificação

Identificação pessoal

Nome completo
Nísia Borralho Martins
Data de nascimento
1998/09/09
Género
Feminino

Nomes de citação

  • Borralho-Martins, Nísia

Identificadores de autor

Ciência ID
4718-EBD3-7B6C
ORCID iD
0000-0001-5713-3240

Endereços de correio eletrónico

  • nisiabmartins@gmail.com (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Biologia do Desenvolvimento

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2023/01/01 - 2027/01/01
Em curso
Biomedical Sciences (Doutoramento)
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2019/09/12 - 2022/01/20
Concluído
Genética Molecular e Biomedicina (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Dissertation Title: "Testing miRNA-cell based strategies to obtain therapeutic secretomes for spinal Amyotrophic Lateral Sclerosis". Nota: 19/20. PTDC/MED-NEU/31395/2017 and LISBOA-01-0145-FEDER-031395" (TESE/DISSERTAÇÃO)
18
2021/09/21 - 2021/09/25
Concluído
SPCAL (Sociedade Portuguesa de Ciências em Animais de Laboratório) de Categoria B de Ciências em Animais de Laboratório - Prático (Pós-Graduação)
Universidade de Lisboa Faculdade de Farmácia, Portugal
18
2021/07/10 - 2021/07/14
Concluído
SPCAL (Sociedade Portuguesa de Ciências em Animais de Laboratório) de Categoria B de Ciências em Animais de Laboratório - Teórico (Pós-Graduação)
Universidade de Lisboa Faculdade de Farmácia, Portugal
18
2016/09 - 2019/06
Concluído
Biologia Celular e Molecular (Licenciatura)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Optimization of the analysis method by HRM (high resolution melting) for genotyping strains of Brucella melitensis, B. abortus and B. suis" (TESE/DISSERTAÇÃO)
16
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2023/01/01 - Atual Investigador (Investigação) Algarve Biomedical Center Research Institute, Portugal
2020/09 - 2021/11 Estagiário de Investigação (Investigação) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2019/02 - 2019/04 Estagiário de Investigação (Investigação) Instituto Nacional de Investigação Agrária e Veterinária, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2022/01/31 - 2022/02/28 Diagnostic Technician for COVID-19 - Nasopharyngeal Exudate Collection and Rapid Antigen Tests Farmácia Carvalho, Portugal
2018/07/01 - 2018/07/30 Internship at the Laboratory of Pathological Anatomy Grupo HPA Saúde, Portugal
Projetos

Bolsa

Designação Financiadores
2023/01/01 - Atual Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation
2022.12867.BD
Bolseiro de Doutoramento
Algarve Biomedical Center Research Institute, Portugal

Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/09 - 2022/01 Development of an autologous exosome-based therapy by engineering microRNAs in microglia and motor-neurons using mice and human models of amyotrophic lateral sclerosis ALS
PTDC/MED-NEU/31395/2017
LISBOA-01-0145- FEDER-031395
Investigador
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Maia-Fernandes, Ana; Martins-Jesus, Ana; Borralho-Martins, Nísia; Pais de Azevedo, Tomás Augusto Barreiros ; Magno, Ramiro; Duarte, Isabel; Raquel P. Andrade. Autor correspondente: Raquel P. Andrade. "SPATIO-TEMPORAL DYNAMICS OF EARLY SOMITE SEGMENTATION IN THE CHICKEN EMBRYO". PlosOne (2024):
    10.1371/journal.pone.0297853
Poster em conferência
  1. Matos, Ana Teresa; Borralho-Martins, Nísia; Loch-Neckel, Gecioni; Vaz, Ana Rita. Autor correspondente: Matos, Ana Teresa. "miRNA Engineering of Pathological Microglia as a Promising Therapeutic Strategy for Amyotrophic Lateral Sclerosis". Trabalho apresentado em Federation of European Neuroscience Societies (FENS) Regional Meeting, 2023.
  2. Matos, Ana Teresa; Loch-Neckel, Gecioni; Borralho-Martins, Nísia; Vaz, Ana Rita; Brites, Dora. Autor correspondente: Matos, Ana Teresa. "Inhibiting miR-125b Overexpression in Amyotrophic Lateral Sclerosis Spinal Microglia Restores their Homeostatic Profile". Trabalho apresentado em VI Symposium of the Portuguese Glial Network, 2022.
  3. Matos, Ana Teresa; Martins, Nísia; Loch-Neckel, Gecioni; Vaz, Ana Rita; Brites, Dora. "Inhibiting miR-125b overexpression in ALS spinal microglia restores their homeostatic profile". Trabalho apresentado em VI Symposium of the Portuguese Glia Network, 2022.
  4. Matos, Ana Teresa; Martins, Nísia; Loch-Neckel, Gecioni; Vaz, Ana Rita; Brites, Dora. "miR-125b inhibitor recovers microglial homeostatic profile conveying neuroprotection in ALS". Trabalho apresentado em iMed.ULisboa Meeting 2022, 2022.
  5. Vaz, Ana Rita; Matos, Ana Teresa; Martins, Nísia; Loch-Neckel, Gecioni; Barbosa, Marta; Brites, Dora. "Regeneration of Microglia Homeostasis and Paracrine Signaling in Models of Spinal ALS Disease". Trabalho apresentado em Symposium SPN - Molecular mechanisms of neurodegeneration -thinking outside the box. Congresso Sociedade Portuguesa de Neurociências, 2021.
  6. Martins, Nísia; Matos, Ana Teresa; Loch-Neckel, Gecioni; Vaz, Ana Rita; Brites, Dora. "Testing the Benefits of the miRNA-Reshaped Secretome from Motor Neurons in Spinal 3D Cultures Using ALS Models". Trabalho apresentado em IMed.ULisboa Meeting 2021, 2021.
  7. Matos, Ana Teresa; Martins, Nísia; Loch-Neckel, Gecioni; Vaz, Ana Rita; Brites, Dora. "Studying the Benefits of the Regulation of Inflammatory-miRNAs in Rescuing Microglia Function in ALS". Trabalho apresentado em IMed.ULisboa Meeting 2021, 2021.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2025/02/21 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation 3rd Annual UAlg Doctoral Meeting
Universidade do Algarve (Portugal)
2025/01/24 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation ABC-RI Pizza-Club Seminar
Algarve Biomedical Center Research Institute (Portugal)
2024/12/17 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation Annual Journey of Doctoral Students in Biomedical Sciences
Faculdade de Medicina e Ciências Biomédicas - Ualg
2024/07/26 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation DevoStem Meetings
Algarve Biomedical Center Research Institute (Portugal)
2024/05/31 "A day in the life of a scientist" - Speaker to perform interactive seminars at several elementary schools in southern Portugal, inspiring young students to explore science and envision careers in STEM
(Portugal)
2024/05/09 Functional Relevance of the Embryo Molecular Clock Oscillations Geneticamente Falando com
Portuguese Society of Genetics (Portugal)
2024/03/20 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation 2nd Annual UAlg Doctoral Meeting
Universidade do Algarve (Portugal)
2024/01/26 Manipulating The Clock: Functional Relevance Of Molecular Clock Oscillations In Early Embryo Development IX Clinical Biochemistry Workshop
Portuguese Society of Biochemistry (Faro, Portugal)
2024/01/25 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation ABC-RI Pizza-Club Seminar
Algarve Biomedical Center Research Institute (Portugal)
2023/12/19 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiatio Annual Journey of Doctoral Students in Biomedical Sciences
Faculdade de Medicina e Ciências Biomédicas - Ualg
2023/02/24 Embryo Clock-Dependent Epigenome Dynamics in Temporal Control of Cell Differentiation DevoStem Meetings
Algarve Biomedical Center Research Institute (Portugal)
2022/03/31 Testing miRNA-Cell Based Strategies To Obtain Therapeutic Secretomes For Spinal ALS ABC-RI Pizza-Club Seminar
Algarve Biomedical Center Research Institute (Faro)
2021/02 Testing the Benefits of the miRNA-Reshaped Secretome from Motor Neurons in Spinal 3D Cultures Using ALS Models Jornadas Intercalares das Dissertações Anuais dos Mestrados do Departamento de Química e Departamento de Ciências da Vida
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia (Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2024/04/01 - 2024/06/08 Estudo funcional do relógio molecular embrionário durante a gastrulação
Coorientador de Isabela Pinheiro Pessôa
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2024/03/01 - 2024/04/08 Estudo funcional do relógio molecular embrionário durante a gastrulação
Coorientador de Beatriz Rodrigues Santos
Curricular Internship (Master’s in Medicine)
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2023/05 - 2023/07 Avaliação Funcional do Relógio Molecular no Desenvolvimento Embrionário
Coorientador de Maria Assunção Cordeiro Piloto
Algarve Biomedical Center Research Institute, Portugal

Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2023/03 - 2023/04 Estudo do relógio embrionário no desenvolvimento do membro do embrião de galinha
Coorientador de Maria Inês Águas Rodrigues Pinheiro
Curricular Internship (Master’s in Medicine)
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2024/10/13 - Atual Communication Leader of the Faro Team of Pint of Science Portugal. Pint of Science is a non-profit association whose main goal is to make scientific discussion accessible to the general population. To achieve this, we annually organize an international science communication festival, where researchers from different fields are invited to present their projects in a simple and engaging manner in a relaxed environment such as a bar/pub. (2025/05/19 - 2025/05/21)
Festival (Membro da Comissão Organizadora)
2023/01 - Atual DevoStem Meetings: Internal ABC-RI Meetings with the goal of helping all members to discuss their projects and eventual problems/obstacles that we are currently dealing with, as these interactions contribute to the collaborative and supportive environment we aim to foster. (2023/01)
Encontro (Membro da Comissão Organizadora)
Algarve Biomedical Center Research Institute, Portugal
2018/04/11 - 2018/04/11 EXPO FCT NOVA - Dia Aberto da FCT NOVA: With the motto "see to choose", the initiative is a showcase of activities in science and engineering, therefore being an excellent opportunity to help in choosing areas for the continuation of studies by secondary school students and have a close contact with the university environment of one of the most prestigious Science and Engineering Universities in the country. (2018/04/11 - 2018/04/11) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/02/07 - 2018/02/08 JORTEC - Jornadas Tecnológicas da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa: The initiative aims to provide contact between future engineers/scientists/professionals from different areas and also intends to promote the sharing of knowledge and experiences and to create awareness of the potential of each course. (2018/02/07 - 2018/02/08) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2025/02/25 - 2025/02/26 UALG Open Days - With the aim of promoting the educational offerings for 2025/2026 and showcasing the pedagogical and scientific work carried out at UAlg, the Open Days feature a varied program that includes a range of informative, pedagogical, experimental, and recreational activities.
Universidade do Algarve, Portugal

Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2024/07/08 - 2024/07/13 EMBO EGGED Practical Course - EGGED will bring together the world’s chicken embryology experts to share their skills and showcase the exceptional resourcefulness of the chicken embryo. The workshop will also provide an opportunity for scientists to share, learn and develop embryological techniques that use the chicken embryo and importantly, to shape the future of chicken developmental biology resources and approaches. EMBO EGGED Practical Course
The University of Edinburgh The Roslin Institute, Reino Unido
2024/04/29 - 2024/05/01 Avian Research Symposium 2024 - A meeting to share and discuss research in avian biology with a focus on highlighting early-career researchers and creating networking opportunities between labs and institutions.
Simpósio
Avian Research Symposium 2024
The University of Edinburgh The Roslin Institute, Reino Unido

The University of Edinburgh Royal Dick School of Veterinary Studies, Reino Unido
2024/04/16 - 2024/04/17 UALG Open Days - With the aim of promoting the educational offerings for 2025/2026 and showcasing the pedagogical and scientific work carried out at UAlg, the Open Days feature a varied program that includes a range of informative, pedagogical, experimental, and recreational activities.
Universidade do Algarve, Portugal

Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2024/04/11 - 2024/04/11 Hands-on Workshop “Quantification in ImageJ"
Oficina (workshop)
Hands-on Workshop “Quantification in ImageJ"
Algarve Biomedical Center Research Institute, Portugal
2024/03/19 - 2024/03/22 EMBO | EMBL Symposium - Biological oscillators: rhythms and synchronisation across scales
Simpósio
EMBO | EMBL Symposium - Biological oscillators: rhythms and synchronisation across scales
European Molecular Biology Laboratory, Alemanha
2024/01/26 - 2024/01/26 IX Clinical Biochemistry Workshop
Oficina (workshop)
IX Clinical Biochemistry Workshop
Sociedade Portuguesa de Bioquímica, Portugal
2023/11/10 - 2023/11/10 Development in Action (DiA Meeting) - Inspiring Embryonic Minds
Encontro
Development in Action (DiA Meeting) - Inspiring Embryonic Minds
Sociedade Portuguesa de Biologia do Desenvolvimento, Portugal
2023/09/26 - 2023/10/26 Developmental Biology 14th Course – From Stem cells to Morphogenesis The aim of the program is to provide a comprehensive coverage of the paradigms, problems and technologies of modern Developmental Biology paying particular attention to stem cells. Training in theoretical and experimental aspects of normal and abnormal development is developed through a variety of embryonic systems using state-of-the-art instrumentation and methodology. Developmental Biology 14th Course – From Stem cells to Morphogenesis
Sorbonne Université - Campus Pierre et Marie Curie, França

Institut Curie, França
2023/07/18 - 2023/07/21 EMBO | EMBL Symposium: Theory and concepts in biology
Simpósio
EMBL Heidelberg Genome Biology, Alemanha
2023/04/18 - 2023/04/19 UALG Open Days - With the aim of promoting the educational offerings for 2025/2026 and showcasing the pedagogical and scientific work carried out at UAlg, the Open Days feature a varied program that includes a range of informative, pedagogical, experimental, and recreational activities.
Universidade do Algarve, Portugal

Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2023/03/09 - 2023/03/09 ChIP Analysis and Chromatin Bioinformatics online workshop by Diagenode
Oficina (workshop)
Diagenode sa BELGIUM EUROPE, Bélgica
2023/03/07 - 2023/03/09 Avian Research Symposium 2023 - A meeting to share and discuss research in avian biology with a focus on highlighting early-career researchers and creating networking opportunities between labs and institutions.
Simpósio
Avian Research Symposium 2023
The University of Edinburgh The Roslin Institute, Reino Unido

The University of Edinburgh Royal Dick School of Veterinary Studies, Reino Unido
2023/03/08 - 2023/03/08 Tagmentation-Based Methods online workshop by Diagenode
Oficina (workshop)
Diagenode sa BELGIUM EUROPE, Bélgica
2023/03/06 - 2023/03/06 Chromatin Immunoprecipitation (ChIP) online workshop by Diagenode
Oficina (workshop)
Diagenode sa BELGIUM EUROPE, Bélgica
2022/12/06 - 2022/12/07 International Conference Ageing With]Out[ Borders
Conferência
Algarve Biomedical Center Research Institute, Portugal
2022/10/16 - 2022/10/20 19th International Congress of Developmental Biology
Congresso
International Society of Developmental Biologists, Estados Unidos

Sociedade Portuguesa de Biologia do Desenvolvimento, Portugal
2022/09/01 - 2022/09/05 Hands-On Molecular Tools Workshop - Fundamental Principles and Standard Techniques used in Molecular Biology
Oficina (workshop)
Centro Champalimaud, Portugal
2021/02 - 2021/05 iMed.ULisboa seminars for a Healthy Science: - Neuro-immune interactions: A holistic paradigm in CNS pathology and regeneration - Dr Dora Brites (26/2); - How to Adapt to a Rapidly Changing Publication Landscape - Dr Ruben Ragg (12/3); - Advanced Cell Culture Models: The use of 3D cultures in in vitro toxicology and regenerative medicine - Dr Joana Miranda - (26/3); - Turning molecules into medicines, lessons for liver disease biology - Dr Cecilia Rodrigues (14/5)
Seminário
iMed.ULisboa Seminars
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2021/04/13 - 2021/04/13 O Futuro da Medicina e Temas Centrais de Vida: Envelhecimento, Estilos de Vida, Ética - organized by Fundação Amélia de Mello in partnership with the Universidade NOVA de Lisboa and NOVA Medical School
Conferência
O Futuro da Medicina e Temas Centrais de Vida: Envelhecimento, Estilos de Vida, Ética
2019/10/31 - 2019/10/31 Champalimaud Cancer Talks - "Serendipities of Acquired Immunity" - Dr. Tasuku Honjo
Conferência
Serendipities of Acquired Immunity
Centro Champalimaud, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2024/03/07 - 2024/03/07 Animal Models - Chicken Embryo (Licenciatura) Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2023/11 - 2023/11 Biologia de Desenvolvimento Biologia de Desenvolvimento (Licenciatura) Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal

Entrevista / Programa (rádio / tv)

Programa Tema
2025/02/05 - 2025/02/05 Semana da Investigação Médica: conversas e reportagens na Antena 1 Semana da Investigação Médica: Algarve Biomedical Center Research Institute

Membro de associação

Nome da associação Tipo de participação
2025/10/01 - Atual Graduate Women in Science (GWIS) Member
2024/10/13 - Atual Pint of Science Portugal Leader of Communication Team
2022/10/03 - Atual Portuguese Society of Developmental Biology (SPBD) Member
2019 - Atual Volunteer at Associação Protagonist Falcon - Demonstration, Treatment and Preservation of Endangered Species, namely birds of prey and reptiles Member
2017 - 2019 Núcleo de Biologia Celular e Molecular (NBCM) - Organization and dynamization of science outreach events (Conferences, Meetings, Workshops) related to the field of Life Sciences with a focus on Cell and Molecular Biology fostering the knowledge of biology to specialized audiences and the general society Member

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2022/02 - Atual Invited National Ambassador of iMed Conference 14.0: iMed Conference is a project by Nova Medical School's Students' Union, that is held in Lisbon since 2009, addressed to the next generation of Life Science's students. The National Ambassadors Programme was created with the goal of reaching a greater number of Educational Institutions and being closer to the national students who want to participate in the conference, aiming to spread information by the faculties of the health science field in a more intimate manner.
Membro
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2023/10/18 - 2023/10/22 Invited National Ambassador of iMed Conference 15.0: iMed Conference is a project by Nova Medical School's Students' Union, that is held in Lisbon since 2009, addressed to the next generation of Life Science's students. The National Ambassadors Programme was created with the goal of reaching a greater number of Educational Institutions and being closer to the national students who want to participate in the conference, aiming to spread information by the faculties of the health science field in a more intimate manner.
Membro
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Distinções

Prémio

2025 Financial Support for 2025 Developmental Biology Gordon Research Seminar/Conference
2023 Scholarship financed by Fundação para a Ciência e Tecnologia (FCT)
Fundação para a Ciência e a Tecnologia, Portugal
2022 Best National Ambassador of iMed Conference 14.0
2016 Honor Board Diploma
Escola Secundária Poeta António Aleixo, Portugal
2015 Honor Board Diploma
Escola Secundária Poeta António Aleixo, Portugal