Identificação pessoal

Nome completo

Alexandre Carmo

Nomes de citação

• Carmo, Alexandre
• Alexandre M Carmo

Identificadores de autor

Ciência ID

5A14-6B60-7C2C

ORCID iD

0000-0002-2508-9799

Google Scholar ID

https://scholar.google.pt/citations?user=kO1md-4AAAAJ&hl=pt-PT

Researcher Id

B-5191-2011

Scopus Author Id

6603934048

Endereços de correio eletrónico

• acarmo@ibmc.up.pt (Profissional)

Telefones

Telefone

• 226074911 (Profissional)

Moradas

• Instituto de Biologia Molecular e Celular. Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Profissional)

Websites

• http://www.i3s.up.pt/research-groups/host-interaction-and-response/cell-activation-gene-expression (Profissional)

Domínios de atuação

• Ciências Médicas e da Saúde - Medicina Básica - Imunologia

	Grau	Classificação
1991/11/17 - 1995/07/29 Concluído	Immunology (Doctor of Philosophy) University of Oxford Wolfson College, Reino Unido "Molecular associations of proteins involved in signal transduction in T lymphocytes" (TESE/DISSERTAÇÃO)
1987/12/13 - 1991/01/11 Concluído	Mestrado em Imunologia (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "The influence of culture conditions of peripheral blood mononuclear cells on the expression of T lymphocyte specific genes" (TESE/DISSERTAÇÃO)	Muito Bom
1982/10/01 - 1987/12/12 Concluído	Bioquímica (Licenciatura) Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal	16

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2015/11/01 - Atual	Investigador principal (carreira) (Investigação)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2008/04/01 - Atual	Investigador principal (carreira) (Investigação)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008/09/01 - 2009/07/31	Investigador visitante (Investigação)	Weatherall Institute of Molecular Medicine, Reino Unido
	Weatherall Institute of Molecular Medicine, Reino Unido
1999/04/01 - 2008/03/31	Investigador Auxiliar (carreira) (Investigação)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2009/12/01 - 2015/09/30	Professor Associado Convidado (Docente Universitário)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Bolsa

	Designação	Financiadores
2025/01/01 - 2026/06/30	A novel role for CD5L in modulating the immune responses against protozoan parasites 2023.14474.PEX 2023.14474.PEX Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2023/03/01 - 2024/08/31	Characterization of invariant Natural Killer T cell phenotype and function in alpha-Galactosidase A deficiency 2022.01788.PTDC 10.54499/2022.01788.PTDC Investigador Instituto de Astrofísica e Ciências do Espaço, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2023/01/01 - 2024/06/30	A novel role for SRCR proteins at the interface of maternal-fetal infections associated with neonatal sepsis 2022.04792.PTDC 2022.04792.PTDC Investigador Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/01 - 2021/12/31	BRAINFLAMME - CD6 as a regulator of T cell signaling and a hotspot for treating neuroinflammation PTDC/MED-IMU/32296/2017 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2016/01/01 - 2020/12/31	FOLSMART - Folate-target nanodevices to activate macrophages for rheumatoid arthritis. H2020-NMP-PILOTS-2015-683356 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	European Commission Concluído
2016/02/01 - 2020/01/31	SRECOGNITE – SRCR proteins as microorganism pattern recognition receptors: a wide search for interactions with pathogenic bacteria Infect-ERA 2015 - ID 121 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2016/04 - 2019/03	Immunomodulatory effect of CD6-targeting in neuroinflammation PTDC/DTP-FTO/3080/2014 Co-Investigador Responsável (Co-IR) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2013/06/01 - 2015/09/30	Do scavenger receptor cysteine-rich proteins interact with host immune mediators or bind pathogen-associated molecular patterns: a comprehensive qualitative and quantitative analysis. 124253 Provided by PTCRIS: 124253 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2012/04/01 - 2015/06/30	Global analysis of alternative polyadenylation regulators and miRNA silencing of immune modulators PTDC/SAU-GMG/116621/2010 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Baylor College of Medicine, Estados Unidos	Fundação para a Ciência e a Tecnologia Concluído
2009/12 - 2013/11	NANOFOL - Folate-based nanobiodevices for integrated diagnosis/therapy targeting chronic inflammatory diseases. NMP4-LA-2009-228827 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	European Commission Concluído
2010/04/01 - 2013/09/30	Functional and biological characterization of SSc5D, a novel molecule of the Scavenger Receptor Cysteine-rich family Provided by PTCRIS: 100588 100588 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2010/01/01 - 2013/04/30	A systematic method for identifying the ligands of T-cell surface molecules 98041 Provided by PTCRIS: 98041 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2008/06/01 - 2011/05/31	Alternative spliced isoforms of CD6: on the cross-roads of T cell activation and the regulation of lymphocyte development 64247 Provided by PTCRIS: 64247 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2005/07/01 - 2008/06/30	Multiple isoforms of CD6 that arise from alternative splicing: their role in the regulation of T cell signaling and at the immunological synapse 56774 Provided by PTCRIS: 56774 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2005/04/01 - 2008/03/31	Analysis of CD5 expression at the surface of T lymphocytes: molecular associations and membrane domain localization Provided by PTCRIS: 56775 56775 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2002/02/01 - 2005/01/31	The biology of the Scavenger receptor cysteine-rich family: CD6 as a model. POCTI/MGI/39071/2001 Investigador responsável Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2001/05 - 2004/10	Targeting signaling pathways as therapy for human cancer POCTI/CBO/34914/99 Co-Investigador Responsável (Co-IR) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído

Projeto

	Designação	Financiadores
2019/01/01 - 2019/12/31	Institute for Research and Innovation in Health Sciences UID/BIM/04293/2019 LA/P/0070/2020 10.54499/LA/P/0070/2020 Instituto Nacional de Engenharia Biomédica, Portugal Universidade do Porto, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2011/01/01 - 2012/12/31	Projecto Estratégico - LA 2 - 2011-2012 PEst-C/SAU/LA0002/2011 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal	Fundação para a Ciência e a Tecnologia Concluído

Publicações

Artigo em revista	Cardoso, M.S.; Gonçalves, R.; Oliveira, L.; Silvério, D.; Téllez, É.; Paul, T.; Sarrias, M.R.; Carmo, A.M.; Saraiva, M.. "CD5L is upregulated upon infection with Mycobacterium tuberculosis with no effect on disease progression". Immunology (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85196625668&partnerID=MN8TOARS. 10.1111/imm.13825 Santos, R.F.; de Sousa Linhares, A.; Steinberger, P.; Davis, S.J.; Oliveira, L.; Carmo, A.M.. "The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling". Cell Communication and Signaling 22 1 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85194218997&partnerID=MN8TOARS. 10.1186/s12964-024-01658-y Oliveira L; Silva MC; Gomes AP; Santos RF; Cardoso MS; Nóvoa A; Luche H; et al. "CD5L as a promising biological therapeutic for treating sepsis". Nature Communications 15 1 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85193351776&partnerID=MN8TOARS. Aceite para publicação • 10.1038/s41467-024-48360-8 Henriques, Sónia N.; Oliveira, Liliana; Santos, Rita F.; Carmo, Alexandre M.. "CD6-mediated inhibition of T cell activation via modulation of Ras". Cell Communication and Signaling 20 1 (2022): http://dx.doi.org/10.1186/s12964-022-00998-x. 10.1186/s12964-022-00998-x Cardoso, M.S.; Santos, R.F.; Almeida, S.; Sá, M.; Pérez-Cabezas, B.; Oliveira, L.; Tavares, J.; Carmo, A.M.. "Physical Interactions With Bacteria and Protozoan Parasites Establish the Scavenger Receptor SSC4D as a Broad-Spectrum Pattern Recognition Receptor". Frontiers in Immunology 12 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85122481820&partnerID=MN8TOARS. 10.3389/fimmu.2021.760770 Carmo, A.M.; Love, P.E.; Marshall, A.J.. "Editorial: Inhibitory Receptors and Pathways of Lymphocytes". Frontiers in Immunology 11 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85089088008&partnerID=MN8TOARS. 10.3389/fimmu.2020.01552 Santos, R.F.; Oliveira, L.; Brown, M.H.; Carmo, A.M.. "Domain-specific CD6 monoclonal antibodies identify CD6 isoforms generated by alternative-splicing". Immunology 157 4 (2019): 296-303. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068083912&partnerID=MN8TOARS. 10.1111/imm.13087 Freitas, R.F.; Basto, A.; Almeida, S.C.P.; Santos, R.F.; Gonçalves, C.M.; Corria-Osorio, J.; Carvalho, T.; et al. "Modulation of CD4 T cell function via CD6-targeting". EBioMedicine 47 (2019): 427-435. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072256661&partnerID=MN8TOARS. 10.1016/j.ebiom.2019.08.008 Gonçalves, C.M.; Henriques, S.N.; Santos, R.F.; Carmo, A.M.. "CD6, a rheostat-type signalosome that tunes T cell activation". Frontiers in Immunology 9 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85059925855&partnerID=MN8TOARS. 10.3389/fimmu.2018.02994 Carvalho, D.O.; Freitas, J.; Nogueira, P.; Henriques, S.N.; Carmo, A.M.; Castro, M.A.; Guido, L.F.. "Xanthohumol inhibits cell proliferation and induces apoptosis in human thyroid cells". Food and Chemical Toxicology 121 (2018): 450-457. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054021358&partnerID=MN8TOARS. 10.1016/j.fct.2018.09.021 Nogueira, E.; Freitas, J.; Loureiro, A.; Nogueira, P.; Gomes, A.C.; Preto, A.; Carmo, A.M.; Moreira, A.; Cavaco-Paulo, A.. "Neutral PEGylated liposomal formulation for efficient folate-mediated delivery of MCL1 siRNA to activated macrophages". Colloids and Surfaces B: Biointerfaces 155 (2017): 459-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019046361&partnerID=MN8TOARS. 10.1016/j.colsurfb.2017.04.023 Oliveira, L.; Carmo, A.M.. "Response: Commentary: the scavenger receptor SSc5D physically interacts with bacteria through the SrCr-containing n-terminal domain". Frontiers in Immunology 8 AUG (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85028352791&partnerID=MN8TOARS. 10.3389/fimmu.2017.01004 Domingues, R.G.; Lago-Baldaia, I.; Pereira-Castro, I.; Fachini, J.M.; Oliveira, L.; Drpic, D.; Lopes, N.; et al. "CD5 expression is regulated during human T-cell activation by alternative polyadenylation, PTBP1, and miR-204". European Journal of Immunology 46 6 (2016): 1490-1503. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973661630&partnerID=MN8TOARS. 10.1002/eji.201545663 Santos, R.F.; Oliveira, L.; Carmo, A.M.. "Tuning T cell activation: The function of CD6 at the immunological synapse and in T cell responses". Current Drug Targets 17 6 (2016): 630-639. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964055216&partnerID=MN8TOARS. Nogueira, E.; Cruz, C.F.; Loureiro, A.; Nogueira, P.; Freitas, J.; Moreira, A.; Carmo, A.M.; et al. "Assessment of liposome disruption to quantify drug delivery in vitro". Biochimica et Biophysica Acta - Biomembranes 1858 2 (2016): 163-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948166510&partnerID=MN8TOARS. 10.1016/j.bbamem.2015.11.008 Carmo, A.M.. "Heads or tails: Betting on CD6 as a resurged target for autoimmune diseases and sepsis". Current Drug Targets 17 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84964057697&partnerID=MN8TOARS. Pereira, C.B.; Bocková, M.; Santos, R.F.; Santos, A.M.; de Araújo, M.M.; Oliveira, L.; Homola, J.; Carmo, A.M.. "The scavenger receptor SSc5D physically interacts with bacteria through the SRCR-containing N-terminal domain". Frontiers in Immunology 7 OCT (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84997514499&partnerID=MN8TOARS. 10.3389/fimmu.2016.00416 Nogueira, E.; Lager, F.; Le Roux, D.; Nogueira, P.; Freitas, J.; Charvet, C.; Renault, G.; et al. "Enhancing methotrexate tolerance with folate tagged liposomes in arthritic mice". Journal of Biomedical Nanotechnology 11 12 (2015): 2243-2252. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941551653&partnerID=MN8TOARS. 10.1166/jbn.2015.2170 Nogueira, E.; Mangialavori, I.C.; Loureiro, A.; Azoia, N.G.; Sárria, M.P.; Nogueira, P.; Freitas, J.; et al. "Peptide Anchor for Folate-Targeted Liposomal Delivery". Biomacromolecules 16 9 (2015): 2904-2910. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941584525&partnerID=MN8TOARS. 10.1021/acs.biomac.5b00823 Da Glória, V.G.; De Araújo, M.M.; Santos, A.M.; Leal, R.; De Almeida, S.F.; Carmo, A.M.; Moreira, A.. "T cell activation regulates CD6 alternative splicing by transcription dynamics and SRSF1". Journal of Immunology 193 1 (2014): 391-399. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903626125&partnerID=MN8TOARS. 10.4049/jimmunol.1400038 Brisslert, M.; Bian, L.; Svensson, M.N.D.; Santos, R.F.; Jonsson, I.-M.; Barsukov, I.; Erlandsson, M.; et al. "S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 11 (2014): 2049-2059. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907983758&partnerID=MN8TOARS. 10.1016/j.bbadis.2014.07.003 Pinto, M.; Carmo, A.M.. "CD6 as a therapeutic target in autoimmune diseases: Successes and challenges". BioDrugs 27 3 (2013): 191-202. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878559392&partnerID=MN8TOARS. 10.1007/s40259-013-0027-4 Nogueira, E.; Loureiro, A.; Nogueira, P.; Freitas, J.; Almeida, C.R.; Härmark, J.; Hebert, H.; et al. "Liposome and protein based stealth nanoparticles". Faraday Discussions 166 (2013): 417-429. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887481690&partnerID=MN8TOARS. 10.1039/c3fd00057e Henriques, T.; Ji, Z.; Tan-Wong, S.M.; Carmo, A.M.; Tian, B.; Proudfoot, N.J.; Moreira, A.. "Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster.". Transcription 3 4 (2012): 198-212. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873285818&partnerID=MN8TOARS. Rollett, A.; Reiter, T.; Nogueira, P.; Cardinale, M.; Loureiro, A.; Gomes, A.; Cavaco-Paulo, A.; et al. "Folic acid-functionalized human serum albumin nanocapsules for targeted drug delivery to chronically activated macrophages". International Journal of Pharmaceutics 427 2 (2012): 460-466. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859105871&partnerID=MN8TOARS. 10.1016/j.ijpharm.2012.02.028 Oliveira, M.I.; Gonçalves, C.M.; Pinto, M.; Fabre, S.; Santos, A.M.; Lee, S.F.; Castro, M.A.A.; et al. "CD6 attenuates early and late signaling events, setting thresholds for T-cell activation". European Journal of Immunology 42 1 (2012): 195-205. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855225261&partnerID=MN8TOARS. 10.1002/eji.201040528 James, J.R.; McColl, J.; Oliveira, M.I.; Dunne, P.D.; Huang, E.; Jansson, A.; Nilsson, P.; et al. "The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins". Journal of Biological Chemistry 286 37 (2011): 31993-32001. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052730531&partnerID=MN8TOARS. 10.1074/jbc.M111.219212 Pinto, P.A.B.; Henriques, T.; Freitas, M.O.; Martins, T.; Domingues, R.G.; Wyrzykowska, P.S.; Coelho, P.A.; et al. "RNA polymerase II kinetics in polo polyadenylation signal selection". EMBO Journal 30 12 (2011): 2431-2444. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958859723&partnerID=MN8TOARS. 10.1038/emboj.2011.156 Bamberger, M.; Santos, A.M.; Gonçalves, C.M.; Oliveira, M.I.; James, J.R.; Moreira, A.; Lozano, F.; Davis, S.J.; Carmo, A.M.. "A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of fyn kinase". Journal of Biological Chemistry 286 35 (2011): 30324-30336. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052235105&partnerID=MN8TOARS. 10.1074/jbc.M111.230102 Fernandes, R.A.; Yu, C.; Carmo, A.M.; Evans, E.J.; Anton van der Merwe, P.; Davis, S.J.. "What Controls T Cell Receptor Phosphorylation?". Cell 142 5 (2010): 668-669. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956167214&partnerID=MN8TOARS. 10.1016/j.cell.2010.08.018 Gonçalves, C.M.; Castro, M.A.A.; Henriques, T.; Oliveira, M.I.; Pinheiro, H.C.; Oliveira, C.; Sreenu, V.B.; et al. "Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily". Molecular Immunology 46 13 (2009): 2585-2596. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650569240&partnerID=MN8TOARS. 10.1016/j.molimm.2009.05.006 Nunes, R.J.; Castro, M.A.A.; Gonçalves, C.M.; Bamberger, M.; Pereira, C.F.; Bismuth, G.; Carmo, A.M.. "Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2". Journal of Immunology 180 2 (2008): 988-997. http://www.scopus.com/inward/record.url?eid=2-s2.0-40449133966&partnerID=MN8TOARS. Coelho, P.A.; Queiroz-Machado, J.; Carmo, A.M.; Moutinho-Pereira, S.; Maiato, H.; Sunkel, C.E.. "Dual role of topoisomerase II in centromere resolution and aurora B activity". PLoS Biology 6 8 (2008): 1758-1777. http://www.scopus.com/inward/record.url?eid=2-s2.0-50249129235&partnerID=MN8TOARS. 10.1371/journal.pbio.0060207 Kearney, A.; Avramovic, A.; Castro, M.A.A.; Carmo, A.M.; Davis, S.J.; Van Der Merwe, P.A.. "The contribution of conformational adjustments and long-range electrostatic forces to the CD2/CD58 interaction". Journal of Biological Chemistry 282 18 (2007): 13160-13166. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250370503&partnerID=MN8TOARS. 10.1074/jbc.M700829200 Castro, M.A.A.; Oliveira, M.I.; Nunes, R.J.; Fabre, S.; Barbosa, R.; Peixoto, A.; Brown, M.H.; et al. "Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse". Journal of Immunology 178 7 (2007): 4351-4361. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947649690&partnerID=MN8TOARS. Evans, E.J.; Castro, M.A.A.; O'Brien, R.; Kearney, A.; Walsh, H.; Sparks, L.M.; Tucknott, M.G.; et al. "Crystal structure and binding properties of the CD2 and CD244 (2B4)-binding protein, CD48". Journal of Biological Chemistry 281 39 (2006): 29309-29320. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749378972&partnerID=MN8TOARS. 10.1074/jbc.M601314200 James, J.R.; Oliveira, M.I.; Carmo, A.M.; Iaboni, A.; Davis, S.J.. "A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer". Nature Methods 3 12 (2006): 1001-1006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751215258&partnerID=MN8TOARS. 10.1038/nmeth978 Nunes, R.J.; Castro, M.A.A.; Carmo, A.M.. "Protein crosstalk in lipid rafts". Advances in Experimental Medicine and Biology 584 (2006): 127-136. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934439684&partnerID=MN8TOARS. 10.1007/0-387-34132-3_10 Castro, M.A.A.; Nunes, R.J.; Oliveira, M.I.; Tavares, P.A.; Simões, C.; Parnes, J.R.; Moreira, A.; Carmo, A.M.. "OX52 is the rat homologue of CD6: Evidence for an effector function in the regulation of CD5 phosphorylation". Journal of Leukocyte Biology 73 1 (2003): 183-190. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037241608&partnerID=MN8TOARS. 10.1189/jlb.0902437 Castro, M.A.A.; Tavares, P.A.; Almeida, M.S.; Nunes, R.J.; Wright, M.D.; Mason, D.; Moreira, A.; Carmo, A.M.. "CD2 physically associates with CD5 in rat T lymphocytes with the involvement of both extracellular and intracellular domains". European Journal of Immunology 32 5 (2002): 1509-1518. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036104886&partnerID=MN8TOARS. 10.1002/1521-4141(200205)32:5<1509::AID-IMMU1509>3.0.CO;2-T Carmo, A.M.; Castro, M.A.A.; Arosa, F.A.. "CD2 and CD3 associate independently with CD5 and differentially regulate signaling through CD5 in Jurkat T cells". Journal of Immunology 163 8 (1999): 4238-4245. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032828669&partnerID=MN8TOARS. Arosa, F.A.; De Jesus, O.; Porto, G.; Carmo, A.M.; De Sousa, M.. "Calreticulin is expressed on the cell surface of activated human peripheral blood T lymphocytes in association with major histocompatibility complex class I molecules". Journal of Biological Chemistry 274 24 (1999): 16917-16922. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033546416&partnerID=MN8TOARS. 10.1074/jbc.274.24.16917 Carmo, A.M.; Wright, M.D.. "Association of the transmembrane 4 superfamily molecule CD53 with a tyrosine phosphatase activity". European Journal of Immunology 25 7 (1995): 2090-2095. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029067385&partnerID=MN8TOARS. 10.1002/eji.1830250743 Garnett, D.; Neil Barclay, A.; Carmo, A.M.; Beyers, A.D.. "The association of the protein tyrosine kinases p56lck and p60fyn with the glycosyl phosphatidylinositol-anchored proteins Thy-1 and CD48 in rat thymocytes is dependent on the state of cellular activation". European Journal of Immunology 23 10 (1993): 2540-2544. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027431093&partnerID=MN8TOARS. 10.1002/eji.1830231024 Carmo, A.M.; Mason, D.W.; Beyers, A.D.. "Physical association of the cytoplasmic domain of CD2 with the tyrosine kinases p56 lck and p59 fyn". European Journal of Immunology 23 9 (1993): 2196-2201. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027218372&partnerID=MN8TOARS. 10.1002/eji.1830230922
Capítulo de livro	Carmo, Alexandre M.; Henriques, Sónia N.. "Cell Activation and Signaling in Lymphocytes". In Tissue-Specific Cell Signaling, 133-161. Springer International Publishing, 2020. 10.1007/978-3-030-44436-5_5 Oliveira, Liliana; Santos, Rita F.; Carmo, Alexandre M.. "CD6". In Encyclopedia of Signaling Molecules, 937-943. Springer International Publishing, 2018. 10.1007/978-3-319-67199-4_101856 Carmo AM; Sreenu VB. "Systematic analysis of Scavenger Receptor Cysteine-rich family domains encoded in the Human Genome". In Bioinformatics – Trends and methodologies, 195-210. London, Reino Unido: InTech, 2011.
Documento de trabalho	Oliveira, L.; Gomes, A.P.; Santos, R.F.; Cardoso, M.S.; Nóvoa, A.; Luche, H.; Gartner, F.; et al. 2022. "CD5L constraints acute and systemic inflammation and can be a novel potent therapeutic agent against sepsis". https://www.biorxiv.org/content/10.1101/2022.03.08.483540v1. 10.1101/2022.03.08.483540

Propriedade Intelectual

Patente	Alexandre M Carmo; Oliveira, Liliana. 2022. "Recombinant Human CD5L protein, active fragments or peptides derived thereof and pharmaceutical composition comprising the recombinant human CD5L protein, active fragments or peptides derived thereof for the treatment of acute infectious diseases, inflammatory diseases and sepsis.". Portugal. Pendente
Pedido provisório de patente	2020. "Scavenger circulating protein CD5L to treat inflammation-related diseases and sepsis".

Outros

Outra produção

Antibody blockade of the PSGL-1 immune checkpoint enhances T-cell responses to B-cell lymphoma. 2024. dos Santos, N.R.; Pereira, J.; Ferreira, F.; Matos, A.; Pereira, D.; Santos, R.; Carmo, A.; Oliveira, M.; Machado, J.C.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85190557218&partnerID=MN8TOARS. 10.21203/rs.3.rs-4018077/v1

Prémio

2020	Born from Knowledge Award Agência Nacional de Inovação SA, Portugal