Mark Stephen Gibson (5B19-F05C-F2AD)

Curriculum Vitae

Mark Stephen Gibson

Mark Stephen Gibson studied for his BSc degree in Biochemistry at the University of Surrey from 1999-2003. He developed his long standing interest in Immunogenetics at the Anthony Nolan Trust from 2003-2006 before undertaking his Master of Science degree in Clinical Biochemistry and Molecular Biology at the University of Surrey. He then completed his PhD in Infection and Immunity at The Pirbright Institute and University College London from 2007-2011. During this time, he cloned & characterised novel members of the chicken Interleukin-1 family. Next, Mark took on a Postdoc position within the Immunogenetics Group at the Pirbright Institute where he characterised Natural Killer cell receptor diversity and function in cattle. After moving to Portugal, he undertook a Postdoc position at the Chronic Diseases Research Centre (CEDOC) in Lisbon, focussed on understanding the molecular mechanisms that regulate sterile inflammation in atherosclerosis. Mark is now a Senior Postdoc in the RNA Systems Biology group within the Biosystems and Integrative Sciences Institute (BioISI), Universidade de Lisboa. His project aims to characterise the role of microRNAs in T-cell function and anti-HIV defence. Mark is also a junior lecturer at Faculdade de Ciencias, Universidade de Lisboa. To date, he has published ten peer-reviewed articles in journals.

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Identificação

Identificação pessoal

Nome completo: Mark Stephen Gibson

Nomes de citação

Gibson, Mark S

Identificadores de autor

Ciência ID: 5B19-F05C-F2AD
ORCID iD: 0000-0001-9732-8915
Researcher Id: E-5574-2015

Endereços de correio eletrónico

m.s.gibson81@gmail.com (Pessoal)

Domínios de atuação

Ciências Médicas e da Saúde - Medicina Básica - Imunologia
Ciências Naturais - Ciências Biológicas - Biologia Molecular

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Português	Utilizador elementar (A2)	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A2)

Formação

	Grau	Classificação
2012/01/28 Concluído	PhD in Infection and Immunity (Doutoramento) University College London, Reino Unido "A genetic and functional analysis of the chicken interleukin-1 gene family" (TESE/DISSERTAÇÃO)	Approved
2007/09/28 Concluído	MSc in Clinical Biochemistry and Molecular Biology (Mestrado) University of Surrey, Reino Unido "Characterisation of the human PERIOD3 gene promoter following construction of a deletion library " (TESE/DISSERTAÇÃO)	Merit
2003/05/23 Concluído	Bachelor of Science (BSc) Biochemistry (with honours) (Licenciatura) University of Surrey, Reino Unido "PPAR gene expression in cholesterol fed rabbits" (TESE/DISSERTAÇÃO)	Second Class Honours (2ii) - 14 valores

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2003/09/01 - 2006/10/02	Assistente de Investigação (carreira) (Investigação)	Anthony Nolan, Reino Unido

2001/09/03 - 2002/08/01	Assistente de Investigação (carreira) (Investigação)	University College London Division of Biosciences, Reino Unido

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2019/10/02 - Atual	Leitor (Docente Universitário)	Universidade de Lisboa Faculdade de Ciências, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2018/11/12 - Atual	Senior Post-doctoral research scientist (full time). Project: Exploring the role of microRNAs in T cell function and anti-HIV defence.	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal

2016/01/01 - 2018/01/30	Post-doctoral research scientist (full time) Project: Understanding the molecular mechanisms that regulate sterile inflammation in atherosclerosis	Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

2012/08/31 - 2015/10/14	Post-doctoral research scientist (full time) Project: Characterisation of Natural Killer cell receptor diversity & function in cattle	Pirbright Institute, Reino Unido

2012/02/13 - 2012/08/30	Post-doctoral research scientist (full time) Project: Characterisation of IL-18 binding protein in the chicken	Pirbright Institute - Compton, Reino Unido

2007/10/01 - 2011/09/30	PhD Student (full time)	Pirbright Institute - Compton, Reino Unido

Projetos

Bolsa

	Designação	Financiadores
2018/11/12 - Atual	miRiAD - Exploring the role of microRNAs in T cell function and anti-HIV defense PTDC/BIA-CEL/29257/2017 Investigador Pós-doutorado Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2014/09 - 2017/08	Restriction of avian viruses by host interferon-inducible transmembrane proteins (IFITMs) BB/L003996/1	Biotechnology and Biological Sciences Research Council

Projeto

	Designação	Financiadores
2012/08/31 - 2015/10/14	Dissecting the functional impact of natural killer cell receptor variation in cattle BB/J006211/1 Bolseiro de Pós-Doutoramento Pirbright Institute, Reino Unido	Biotechnology and Biological Sciences Research Council

Outro

	Designação	Financiadores
2007/10/01 - 2011/09/30	BBSRC-funded studentship: Genetic and functional analysis of the chicken interleukin-1 gene family info:eu-repo/grantAgreement/RCUK/BBSRC/BBS2%FE2%FI2%F00001345/GB Bolseiro de Doutoramento Pirbright Institute - Compton, Reino Unido	UK Research and Innovation Concluído

Produções

Publicações

Artigo em revista

Gibson, Mark S.; Steyn, Angela; Kealy, David; Kaspers, Bernd; Fife, Mark S.. "Molecular cloning and characterisation of chicken IL-18 binding protein". Developmental & Comparative Immunology 114 (2020): 103850. http://dx.doi.org/10.1016/j.dci.2020.103850.
Acesso aberto • Publicado • 10.1016/j.dci.2020.103850
Mark S. Gibson; Alasdair J. Allan; Nicholas D. Sanderson; James Birch; Simon Gubbins; Shirley A. Ellis; John A. Hammond. "Two Lineages of KLRA with Contrasting Transcription Patterns Have Been Conserved at a Single Locus during Ruminant Speciation". The Journal of Immunology (2020): ji1801363-ji1801363. https://doi.org/10.4049/jimmunol.1801363.
10.4049/jimmunol.1801363
Gibson, Mark. "Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis". Frontiers in Physiology (2018): http://europepmc.org/articles/PMC6029489.
10.3389/fphys.2018.00654
Gibson, Mark. "The evolution of the natural killer complex; a comparison between mammals using new high-quality genome assemblies and targeted annotation". Immunogenetics (2017):
10.1007/s00251-017-0973-y
Gibson, M. S.; Kaiser, P.; Fife, M.. "The chicken IL-1 family: evolution in the context of the studied vertebrate lineage". Immunogenetics 66 7-8 (2014): 427-38.
10.1007/s00251-014-0780-7
Smith, S. E.; Gibson, M. S.; Wash, R. S.; Ferrara, F.; Wright, E.; Temperton, N.; Kellam, P.; Fife, M.. "Chicken interferon-inducible transmembrane protein 3 restricts influenza viruses and lyssaviruses in vitro". J Virol 87 23 (2013): 12957-66.
10.1128/JVI.01443-13
Gibson, M. S.; Fife, M.; Bird, S.; Salmon, N.; Kaiser, P.. "Identification, cloning, and functional characterization of the IL-1 receptor antagonist in the chicken reveal important differences between the chicken and mammals". J Immunol 189 2 (2012): 539-50.
10.4049/jimmunol.1103204
Gibson, M. S.; Salmon, N.; Bird, S.; Kaiser, P.; Fife, M.. "Identification, cloning and characterisation of interleukin-1F5 (IL-36RN) in the chicken". Dev Comp Immunol 38 1 (2012): 136-47.
10.1016/j.dci.2012.04.014
Archer, S. N.; Carpen, J. D.; Gibson, M.; Lim, G. H.; Johnston, J. D.; Skene, D. J.; von Schantz, M.. "Polymorphism in the PER3 promoter associates with diurnal preference and delayed sleep phase disorder". Sleep 33 5 (2010): 695-701.
Kaiser, P.; Wu, Z.; Rothwell, L.; Fife, M.; Gibson, M.; Poh, T. Y.; Shini, A.; Bryden, W.; Shini, S.. "Prospects for understanding immune-endocrine interactions in the chicken". Gen Comp Endocrinol 163 1-2 (2009): 83-91.
10.1016/j.ygcen.2008.09.013
Gibson, M. S.; Kaiser, P.; Fife, M.. "Identification of chicken granulocyte colony-stimulating factor (G-CSF/CSF3): the previously described myelomonocytic growth factor is actually CSF3". J Interferon Cytokine Res 29 6 (2009): 339-43.
10.1089/jir.2008.0103

Propriedade Intelectual

Patente

Gibson, Mark S. 2019. "Avian cells for improved virus production".

Atividades

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2021/02/01 - Atual	Dissecting new regulatory mechanisms in retroviral integration and replication: the role of miR-34c-5p in HIV-1 infection Coorientador	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2017/03/01 - 2017/11/24	Career Opportunities for PostDoctoral Researchers in Life Sciences brought together postdoctoral researchers from across Portugal. The inaugural event hosted a Job Fair, that aimed to promote new career prospects and opportunities for PhD holders. Individuals from key industries and companies showcased their mission and values, and provided PhD holders the opportunity to apply for jobs. Additionally, several workshops presented alternative career options that exist away from the lab. A Scientific Symposium for post-docs preceded the Job Fair. (2017/11/22 - 2017/11/24) Outro (Membro da Comissão Organizadora)

Arbitragem científica em revista

	Nome da revista (ISSN)	Editora
2020/02/12 - Atual	HLA (2059-2310)	Wiley (Blackwell Publishing)
2018/10 - Atual	The Journal of Leukocyte Biology (1938-3673)	Society for Leukocyte Biology
2016/02/01 - Atual	Scientific Reports (2045-2322)	Springer Science and Business Media LLC
2014/07 - Atual	PLoS ONE (1932-6203)	Public Library of Science
2013/08 - Atual	Cytokine (1096-0023)	Elsevier

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2016/10 - 2017/12	CEDOC Post-doc committee Membro	Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2012/06 - 2012/10	Research department representative on the rebranding committee Membro	Pirbright Institute - Compton, Reino Unido
2009/10 - 2010/10	Student representative on the academic committee Membro	Pirbright Institute - Compton, Reino Unido
2005 - 2006	Research department representative on the staff forum Membro	Anthony Nolan, Reino Unido