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Iris is an Assistant Researcher at S2AQUAcoLAB and expert in Molecular Biology and Genetics. She completed her PhD (2015) in Biomedical Sciences in the University of Algarve in collaboration with the Centre Hospitalier Universitaire de Quebec, Canada, where she worked with several human, mammal and fish adherent cell lines, as well as primary suspension cell cultures. Then, due to her willing to be constantly learning, she changed her field to work on Personalized Medicine in Cystic Fibrosis, and for 5 years she was part of the Cystic Fibrosis Research Lab in BioISI (University of Lisbon - Faculty of Sciences), where she was the responsible for the only biobank of intestinal organoids, primary bronchial, tracheal and nasal cells in Portugal, with samples from more than 130 donors. During these years, she was an integrant part of HIT-CF, an European Consortium funded by H2020. Now, and ready to "navigate in unknown waters", she is the responsible for the genetic and molecular tests performed at S2AQUA, promoting a connection between Molecular Biology and Aquaculture. Through an early pathogen detection and identification, as well as gene expression analyses, Iris uses her background in Molecular Biology to decrease the incidence of disease outbreaks or select animals with the most important traits for S2AQUA associates. She is also the PI of the Portuguese Blue Biobank in S2AQUA, a PRR funded project that aims at increasing the current knowledge of the planet’s biodiversity, and contributing to the international visibility of national bioresources and its economic valorization in international chains. So far, she has published 34 papers in peer review international journals, of which 13 as first author, and she has 11 publications in congress books as 1st author. She has a 12 H-index in Scopus and Google Scholar. She was invited to present her work in several international and national meetings (38 Oral presentations and 24 Conference Posters) and to be supervisor of several undergrad (13), MSc (10) and PhD (1) students. She also participated in the organization of 1 national conference, and 3 national workshops. She was also invited to discuss 2 MSc thesis as main arguer jury and 1 PhD thesis. She was invited to be assistant professor of Physiology (2021) at the University of Lisbon. She is the recipient of 9 national and international awards, namely the Best Young Investigator Award awarded by the European Cystic Fibrosis Society in 2018 and 2021 and the Alumni Career Award by the University of Algarve in 2023. During this path she has established national and international collaborations, crucial to become a successful independent scientist willing to establish innovative lines of research.
Identificação

Identificação pessoal

Nome completo
Iris Silva

Nomes de citação

  • Silva, Iris AL

Identificadores de autor

Ciência ID
8319-EDFC-1260
ORCID iD
0000-0002-8062-5558
Google Scholar ID
Iris A.L. Silva
Researcher Id
U-5740-2017

Endereços de correio eletrónico

  • iasilva@fc.ul.pt (Profissional)
  • iris.silva@s2aquacolab.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Médicas e da Saúde - Ciências da Saúde
  • Ciências Naturais - Ciências Biológicas - Biologia Marinha
  • Ciências Naturais - Ciências Biológicas - Métodos de Investigação Bioquímica
  • Ciências Agrárias - Agricultura, Silvicultura e Pescas - Pescas
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética
  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Médicas e da Saúde - Medicina Básica - Genética Humana
  • Ciências Naturais - Ciências Biológicas - Microbiologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1)
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2011/01/01 - 2015/12/15
Concluído
PhD in Biomedical Sciences (Doutoramento)
Universidade do Algarve, Portugal
"Genetic and Functional Analysis of PDB6 locus in Paget's Disease of Bone" (TESE/DISSERTAÇÃO)
Very good unanimously (distinction/honors)
2009/09 - 2011/10
Concluído
Master in Biomedical Sciences (Mestrado integrado)
Universidade do Algarve, Portugal
"Role of Xeroderma pigmentosum group-D (XPD) in gene expression regulation" (TESE/DISSERTAÇÃO)
18/20
2006/09 - 2009/07
Concluído
Graduation in Biomedical Sciences (Licenciatura)
Universidade do Algarve, Portugal
"Detecção do Cancro da mama: Testes de diagnóstico precoce e a sua utilidade" (TESE/DISSERTAÇÃO)
16/20
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2022/02/01 - Atual Assistant researcher in Molecular Biology S2AQUAcoLAB, Portugal
S2AQUAcoLAB, Portugal
2017 - 2022/01/31 Postdoc fellowship in the European project: "HIT-CF: Personalized Treatment For Cystic Fibrosis Patients with Ultra-rare CFTR Mutations" financed by the European Commission (H2020) Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2021/11 - 2022/01 Assistant Professor of Physiology Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2017/04/20 - 2017/12/31 Postdoc fellowship in the project: "Characterization of Orphan CFTR Mutations" (FFCUL CC6418) (co- financed by the US CFF - Cystic Fibrosis Foundation) Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2016/10/20 - 2017/04/20 Postdoc fellowship in the project "Prediction of the Clinical Efficacy of CFTR Modulator Drugs Using Intestinal Organoids and Nasal Cells from Patients with Cystic Fibrosis", funded by Gilead Sciences Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2016/01/15 - 2016/08/15 Postdoc fellowship in functional genomics, genetic regulation and cancer. Study the allelic imbalance in gene expression and how it can contribute to susceptibility to breast cancer. Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
2012/01/02 - 2015/12/17 PhD fellowship to elaborate my PhD thesis entitled " Genetic and functional analysis of the PDB6 locus in Paget's disease of bone". Centro de Ciências do Mar, Portugal
2009/09 - 2011/09 Research fellow to elaborate my Master thesis entitled "Molecular cloning and analysis of xpd expression in zebrafish." Centro de Ciências do Mar, Portugal
Centro de Ciências do Mar, Portugal
2009/10/01 - 2010/07/31 Part of a group in CBME, by own initiative, to get more practical experience in lab work such as mice models genotyping. Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
2008/09/01 - 2008/12/01 Volunteering in the service of Medical Oncology of Hospital de Faro, within the scope of my Bachelor thesis, for patient data assessment . Hospital de Faro, Portugal
Projetos

Projeto

Designação Financiadores
2022/10 - Atual Portuguese Blue Biobank
.
Investigador responsável
S2AQUAcoLAB, Portugal
Governo da República Portuguesa
Em curso
2021/09 - 2022/02 TestMed - Study of new drugs response and treatment prediction in organoids from individuals with Cystic Fibrosis
BIOSI#0958
Investigador Pós-doutorado
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Concluído
2018 - 2022 HIT-CF: Personalised Treatment For Cystic Fibrosis Patients With Ultra-rare CFTR Mutations (and beyond)
FCIENCIAS ID CC 307 (GA number 755021)
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
European Commission
Concluído
2018/10/01 - 2021/09/30 Identificação de Novos Fármacos para Fibrose Quística
PTDC/MED-QUI/28800/2017
Fundação para a Ciência e a Tecnologia
Concluído
2018/01 - 2021/03 iDrugCF - Identification of New Drugs for Cystic Fibrosis
-
Investigador
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2017 - 2018 Characterization of Orphan CFTR Mutations
FFCUL CC6418
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Cystic Fibrosis Foundation
Concluído
2016/10 - 2017/04 Prediction of the Clinical Efficacy of CFTR Modulator Drugs Using Intestinal Organoids and Nasal Cells from Patients with Cystic Fibrosis
FFCUL CC6362
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Gilead Sciences Lda
Concluído
2016/03 - 2016/10 GenCar - Genetic Control of Gene Expression in Cancer Risk
FP7-MC-CIG_303745
Bolseiro de Pós-Doutoramento
Concluído
Produções

Publicações

Artigo em conferência
  1. Silva, Iris AL; Ramalho, Sofia; Awatade, Nikhil T; Doušová, Tereza; Centeio, Raquel; Farinha, Carlos M; Amaral, Margarida D. "From the bench to bedside: expanding CFTR modulators to rare mutations by response assessment in patients-derived materials and cellular models.". Trabalho apresentado em 41st European Cystic Fibrosis Conference 2018, 2018.
    Publicado
  2. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Comparative analysis of human and zebrafish OPTN: molecular and evolutionary perspectives". Trabalho apresentado em European Calcified Tissue Society Meeting 2016, 2016.
    Publicado • 10.1530/boneabs.5.P257
  3. Silva, Iris AL; Conceição, Natércia; Cancela, M. Leonor. "OPTN and CCDC3 share a bidirectional promoter region that is regulated by NFkB". Trabalho apresentado em European Calcified Tissue Society Meeting 2016, 2016.
    Publicado • 10.1530/boneabs.5.P256
  4. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Functional study of Optineurin (OPTN) variants associated with Paget’s disease of bone". 2014.
    Publicado • .
  5. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Functional analysis of a promoter polymorphism of optineurin, a gene associated to Paget's disease of bone.". Trabalho apresentado em European Calcified Tissue Society Meeting 2014, 2014.
    Publicado • 10.1530/boneabs.3.PP191
  6. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Single nucleotide polymorphisms identification and functional analysis in PDB6 locus: a target locus for Paget's disease of bone.". 2013.
    Publicado • 10.1530/boneabs.1.PP481
  7. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Genetic variation in PDB6 locus and Paget´s Disease of Bone.". Trabalho apresentado em V Clinical Biochemistry Workshop, 2012.
    Publicado • .
Artigo em revista
  1. Mafalda Bacalhau; Filipa C. Ferreira; Iris A. L. Silva; Camilla D. Buarque; Margarida D. Amaral; Miquéias Lopes-Pacheco. "Additive Potentiation of R334W-CFTR Function by Novel Small Molecules". Journal of Personalized Medicine (2023): https://doi.org/10.3390/jpm13010102.
    10.3390/jpm13010102
  2. Gimano D Amatngalim; Lisa W Rodenburg; Bente L Aalbers; Henriette HM Raeven; Ellen M Aarts; Dounia Sarhane; Sacha Spelier; et al. "Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia". Life Science Alliance (2022): https://doi.org/10.26508/lsa.202101320.
    10.26508/lsa.202101320
  3. João F. Ferreira; Iris A. L. Silva; Hugo M. Botelho; Margarida D. Amaral; Carlos M. Farinha. "Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids". Cells (2022): https://doi.org/10.3390/cells11152295.
    10.3390/cells11152295
  4. Pinto, Madalena C.; Botelho, Hugo M.; Silva, Iris A.L.; Railean, Violeta; Neumann, Beate; Pepperkok, Rainer; Schreiber, Rainer; Kunzelmann, Karl; Amaral, Margarida D.. "Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis". Journal of Molecular Biology 434 5 (2022): 167436. http://dx.doi.org/10.1016/j.jmb.2021.167436.
    Publicado • 10.1016/j.jmb.2021.167436
  5. Lopes-Pacheco, Miquéias; Bacalhau, Mafalda; Ramalho, Sofia S.; Silva, Iris A. L.; Ferreira, Filipa C.; Carlile, Graeme W.; Thomas, David Y.; et al. "Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A". Cells 11 1 (2022): 136. http://dx.doi.org/10.3390/cells11010136.
    Publicado • 10.3390/cells11010136
  6. Silva, I.A.L.; Laselva, O.; Lopes-Pacheco, M.. "Advances in Preclinical In Vitro Models for the Translation of Precision Medicine for Cystic Fibrosis". Journal of Personalized Medicine 12 8 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85137383203&partnerID=MN8TOARS.
    10.3390/jpm12081321
  7. Veit, G.; Silva, I.; Conese, M.; Laselva, O.. "Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis". Frontiers in Molecular Biosciences 9 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85134918398&partnerID=MN8TOARS.
    10.3389/fmolb.2022.975946
  8. Roda, J.; Pinto-Silva, C.; Silva, I.A.I.; Maia, C.; Almeida, S.; Ferreira, R.; Oliveira, G.. "New drugs in cystic fibrosis: what has changed in the last decade?". Therapeutic Advances in Chronic Disease 13 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85130734245&partnerID=MN8TOARS.
    10.1177/20406223221098136
  9. Silva, I.A.L.; Varela, D.; Leonor Cancela, M.; Conceição, N.. "Zebrafish optineurin: genomic organization and transcription regulation". Genome 65 10 (2022): 513-523. http://www.scopus.com/inward/record.url?eid=2-s2.0-85139378313&partnerID=MN8TOARS.
    10.1139/gen-2022-0019
  10. Ramalho, Sofia S.; Silva, Iris A. L.; Amaral, Margarida D.; Farinha, Carlos M.. "Rare Trafficking CFTR Mutations Involve Distinct Cellular Retention Machineries and Require Different Rescuing Strategies". International Journal of Molecular Sciences 23 1 (2021): 24. http://dx.doi.org/10.3390/ijms23010024.
    Publicado • 10.3390/ijms23010024
  11. Madalena C. Pinto; Margarida C. Quaresma; Iris A. L. Silva; Violeta Railean; Sofia S. Ramalho; Margarida D. Amaral. "Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms222313064.
    10.3390/ijms222313064
  12. Juliana Roda; Teresa Teixeira; Iris AI Silva; Teresa Reis Silva; Ricardo Ferreira; Margarida D. Amaral; Guiomar Oliveira. "Pediatric population with cystic fibrosis in the centre of Portugal: Candidates for new therapies". Jornal de Pediatria (2021): https://doi.org/10.1016/j.jped.2021.05.010.
    10.1016/j.jped.2021.05.010
  13. Pinto, Madalena C; Silva, Iris AL; Figueira, Miriam F; Amaral, Margarida D; Lopes-Pacheco, Miquéias. "Pharmacological Modulation of Ion Channels for the Treatment of Cystic Fibrosis". Journal of Experimental Pharmacology Volume 13 (2021): 693-723. http://dx.doi.org/10.2147/jep.s255377.
    Aceite para publicação • 10.2147/jep.s255377
  14. Iris A. L. Silva; Violeta Railean; Aires Duarte; Margarida D. Amaral. "Personalized Medicine Based on Nasal Epithelial Cells: Comparative Studies with Rectal Biopsies and Intestinal Organoids". Journal of Personalized Medicine 11 5 (2021): 421-421. https://doi.org/10.3390/jpm11050421.
    10.3390/jpm11050421
  15. Hagemeijer, Marne C; Vonk, Annelotte M; Awatade, Nikhil T; Silva, Iris A L; Tischer, Christian; Hilsenstein, Volker; Beekman, Jeffrey M; Amaral, Margarida D; Botelho, Hugo M. "An open-source high-content analysis workflow for CFTR function measurements using the forskolin-induced swelling assay". Bioinformatics (2020): http://dx.doi.org/10.1093/bioinformatics/btaa1073.
    Publicado • 10.1093/bioinformatics/btaa1073
  16. Silva, Iris A. L.; Duarte, Aires; Marson, Fernando A. L.; Centeio, Raquel; Doušová, Tereza; Kunzelmann, Karl; Amaral, Margarida D.. "Assessment of Distinct Electrophysiological Parameters in Rectal Biopsies for the Choice of the Best Diagnosis/Prognosis Biomarkers for Cystic Fibrosis". Frontiers in Physiology 11 (2020): http://dx.doi.org/10.3389/fphys.2020.604580.
    Publicado • 10.3389/fphys.2020.604580
  17. Lopes-Pacheco, Miquéias; Silva, Iris A.L.; Turner, Mark J.; Carlile, Graeme W.; Sondo, Elvira; Thomas, David Y.; Pedemonte, Nicoletta; Hanrahan, John W.; Amaral, Margarida D.. "Characterization of the mechanism of action of RDR01752, a novel corrector of F508del-CFTR". Biochemical Pharmacology 180 (2020): 114133. http://dx.doi.org/10.1016/j.bcp.2020.114133.
    Publicado • 10.1016/j.bcp.2020.114133
  18. Quaresma, Margarida C.; Pankonien, Ines; Clarke, Luka A.; Sousa, Luís S.; Silva, Iris A. L.; Railean, Violeta; Doušová, Tereza; Fuxe, Jonas; Amaral, Margarida D.. "Mutant CFTR Drives TWIST1 mediated epithelial mesenchymal transition". Cell Death & Disease 11 10 (2020): http://dx.doi.org/10.1038/s41419-020-03119-z.
    Publicado • 10.1038/s41419-020-03119-z
  19. Luis Sousa; Ines Pankonien; Luka A Clarke; Iris Silva; Karl Kunzelmann; Margarida D Amaral. "KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway". Cells 9 7 (2020): 1607-1607. https://doi.org/10.3390/cells9071607.
    10.3390/cells9071607
  20. Vonk, Annelotte; van Mourik, Peter; Ramalho, Anabela S; Silva, Iris AL; Statia, Marvin; Kruisselbrink, Evelien; Suen, Sylvia WF; et al. "Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids". Star Protocols (2020):
    Acesso aberto • Publicado • 10.1016/j.xpro.2020.100019
  21. Silva, Iris AL; Dous¿ova´, Tereza; Ramalho, Sofia; Centeio, Raquel; Clarke, LA; Holubová, Andrea; Valášková, Iveta; et al. "Organoids as a Personalized Medicine Tool for Ultra-Rare Mutations in Cystic Fibrosis: the Case of S955P and 1717-2A>G". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2020):
    Aceite para publicação
  22. Silva, I.A.L.; Doušová, T.; Ramalho, S.; Centeio, R.; Clarke, L.A.; Railean, V.; Botelho, H.M.; et al. "Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G". Biochimica et Biophysica Acta - Molecular Basis of Disease 1866 11 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85089233854&partnerID=MN8TOARS.
    10.1016/j.bbadis.2020.165905
  23. Simões, Filipa B; Quaresma, Margarida C; Clarke, Luka A; Silva, Iris AL; Pankonien, Ines; Railean, Violeta; Arthur Kmit; Amaral, Margarida D. "TMEM16A chloride channel does not drive mucus production". Life Science Alliance 2 6 (2019): e201900462-e201900462. https://doi.org/10.26508/lsa.201900462.
    Publicado • 10.26508/lsa.201900462
  24. Awatade, Nikhil T.; Ramalho, Sofia; Silva, Iris A.L.; Felício, Verónica; Botelho, Hugo M.; de Poel, Eyleen; Vonk, Annelotte; et al. "R560S: A class II CFTR mutation that is not rescued by current modulators". Journal of Cystic Fibrosis 18 2 (2019): 182-189. http://dx.doi.org/10.1016/j.jcf.2018.07.001.
    Publicado • 10.1016/j.jcf.2018.07.001
  25. Clarke, Luka A.; Awatade, Nikhil T.; Felício, Veronica M.; Silva, Iris A.; Calucho, Maite; Pereira, Luisa; Azevedo, Pilar; et al. "The effect of premature termination codon mutations on CFTR mRNA abundance in human nasal epithelium and intestinal organoids: a basis for read-through therapies in cystic fibrosis". Human Mutation (2018): http://dx.doi.org/10.1002/humu.23692.
    Publicado • 10.1002/humu.23692
  26. Silva, Iris AL; Conceição, Natércia; Gagnon, Édith; Brown, Jacques P.; Cancela, M. Leonor; Michou, Laëtitia. "Molecular effect of an OPTN common variant associated to Paget's disease of bone". PLOS ONE 13 5 (2018): e0197543. http://dx.doi.org/10.1371/journal.pone.0197543.
    Publicado • 10.1371/journal.pone.0197543
  27. Lérias, Joana R.; Pinto, Madalena C.; Botelho, Hugo M.; Awatade, Nikhil T.; Quaresma, Margarida C.; Silva, Iris AL; Wanitchakool, Podchanart; et al. "A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 2 (2018): 421-431. http://dx.doi.org/10.1016/j.bbamcr.2017.11.009.
    Publicado • 10.1016/j.bbamcr.2017.11.009
  28. Silva, Iris AL; Conceição, Natércia; Gagnon, Édith; Caiado, Helena; Brown, Jacques P.; Gianfrancesco, Fernando; Michou, Laëtitia; Cancela, M. Leonor. "Functional effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1864 1 (2018): 143-151. http://dx.doi.org/10.1016/j.bbadis.2017.10.008.
    Publicado • 10.1016/j.bbadis.2017.10.008
  29. Silva, Iris AL; Conceição, Natércia. "Cloning, characterization and analysis of the 5' regulatory region of zebrafish xpd gene". Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 185 (2015): 47-53. http://dx.doi.org/10.1016/j.cbpb.2015.04.003.
    Publicado • 10.1016/j.cbpb.2015.04.003
  30. Roberto, Vânia P; Tiago, Daniel; Silva, Iris AL; Cancela, M. Leonor. "MiR-29a is an enhancer of mineral deposition in bone-derived systems". Archives of Biochemistry and Biophysics 564 (2014): 173-183. http://dx.doi.org/10.1016/j.abb.2014.09.006.
    Publicado • 10.1016/j.abb.2014.09.006
  31. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Can zebrafish be a valid model to study Paget’s disease of bone?". Journal of Applied Ichthyology (2014): http://onlinelibrary.wiley.com/doi/10.1111/jai.12523/abstract.
    Publicado • doi: 10.1111/jai.12523
  32. Silva, Iris AL; Cox, Cymon J; Leite, Ricardo B; Cancela, M. Leonor; Conceição, Natércia. "Evolutionary conservation of TFIIH subunits: Implications for the use of zebrafish as a model to study TFIIH function and regulation". Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 172-173 (2014): 9-20. http://dx.doi.org/10.1016/j.cbpb.2014.03.007.
    Publicado • 10.1016/j.cbpb.2014.03.007
  33. Fazenda, Cindy; Silva, Iris AL; Cancela, M. Leonor. "Molecular characterization of two paralog genes encoding Gla-rich protein (Grp) in zebrafish". Journal of Applied Ichthyology 28 3 (2012): 377-381. http://dx.doi.org/10.1111/j.1439-0426.2012.02004.x.
    Publicado • 10.1111/j.1439-0426.2012.02004.x
  34. Silva, Iris AL; Cancela, M. Leonor; Conceição, Natércia. "Molecular cloning and expression analysis of xpd from zebrafish (Danio rerio)". Molecular Biology Reports 39 5 (2011): 5339-5348. http://dx.doi.org/10.1007/s11033-011-1333-x.
    Publicado • 10.1007/s11033-011-1333-x
Poster em conferência
  1. Silva, Iris AL; Soares, Florbela; Ribeiro, Maria Carolina; Livramento, Marcelo; Pousão-Ferreira, Pedro; Lourenço-Marques Cátia. "Using Molecular Biology to Prevent Marine Fish Disease Outbreaks in Aquaculture". Trabalho apresentado em Jornadas de Acuicultura en el Litoral Suratlántico, 2023.
  2. Silva, Iris AL; Barata, Marisa; Requeijo, Bárbara; Rocha, Mafalda; Rosado, Daniela; Soares, Florbela; Gonçalves, Ana Teresa; et al. Autor correspondente: Silva, Iris AL. "Effect of dietary micro and macroalgae on the performance, gene expression, and oxidative stress of European Seabass, Dicentrarchus labrax". Trabalho apresentado em Aquaculture Europe 2023, 2023.
  3. Silva, Iris AL; Barata, Marisa; Requeijo, Bárbara; Rocha, Mafalda; Rosado, Daniela; Soares, Florbela; Gonçalves, Ana Teresa; et al. Autor correspondente: Silva, Iris AL. "Effect of dietary micro and macroalgae on the performance, gene expression, and oxidative stress if Gilthead Seabream, Sparus aurata". Trabalho apresentado em Aquaculture Europe 2023, 2023.
  4. Pousão-Ferreira, Pedro; Ribeiro, Maria Carolina; Soares, Florbela; Castanho, Sara; Livramento, Marcelo; Silva, Iris AL; Candeias-Mendes, Ana; et al. "NEW MICROALGAE AND PROBIOTIC FORMULATIONS IN THE HEALTH OF MARINE FISH LARVAE". Trabalho apresentado em Latin American & Caribbean Aquaculture 2023, 2023.
  5. Ribeiro, Maria Carolina; Livramento, M; Silva, Iris AL; Castanho, Sara; Candeias-Mendes, Ana; Diogo, P.; Bastos, G.; et al. Autor correspondente: Ribeiro, Maria Carolina. "Novas formulações de microalgas e probióticos para técnica de água verde no cultivo larvar de Corvina (Argyrosomus regius): Impacto no crescimento, resposta ao stress e microbiologia". Trabalho apresentado em III Jornadas de Aquacultura, 2023.
  6. Freitas, Inês; Livramento, M; Pedro, Joana; Sousa, Rui; Silva, Iris AL; Rocha, Mafalda; Requeijo, Bárbara; et al. "EFFECT OF DIETARY PROTEIN HYDROLYSATES AND KYOTORPHIN SUPPLEMENTATION ON THE PERFORMANCE, GENE EXPRESSION, AND OXIDATIVE STRESS OF SEABASS (DICENTRARCHUS LABRAX) JUVENILES". Trabalho apresentado em III Jornadas de Aquacultura, 2023.
  7. Ferreira, JF; Silva, Iris AL; Botelho, Hugo M; Amaral, Margarida; Farinha, CM. "Exploring the role of EPAC1 to stabilize CFTR in intestinal cells". Trabalho apresentado em 17th ECFS Basic Science Conference, 2022.
  8. Botelho, Hugo M; Lopes-Pacheco, Miquéias; Pinto, Madalena C.; Silva, Iris AL; Clarke, Luka; Cachatra, V; Neumann, B; et al. "New kinase therapeutic targets for Cystic Fibrosis from a global functional genomics screen". Trabalho apresentado em 17th ECFS Basic Science Conference, 2022.
  9. Botelho, Hugo M; Lopes-Pacheco, Miquéias; Pinto, Madalena C.; Silva, Iris AL; Clarke, Luka A; Cachatra, V; Neumann, B; et al. "New kinase therapeutic targets for Cystic Fibrosis identified through high-content functional genomics screens". Trabalho apresentado em 5ª Conferência Anual da redeSAÚDE, 2021.
  10. Silva, Iris AL; Duarte, Aires; Marson, Fernando; Centeio, Raquel; Dousova, Tereza; Kunzelmann, Karl; Amaral, Margarida. "Electrophysiological Measurements In Rectal Biopsies: A Better Prognosis Biomarker For CF Disease?". Trabalho apresentado em North American Cystic Fibrosis Conference 2020, 2020.
  11. Silva, Iris AL; Ramalho, Anabela S; Vonk, Annelotte M; Suen, Sylvia WF; Bierlaagh, M; Amaral, Margarida; Vermeulen, François; et al. "First Results Of The HIT-CF Organoid Study: Intestinal Organoids Derived From Cf Patients With Ultra-Rare Mutations Respond To The Combination Of Dirocaftor And Posenacaftor". Trabalho apresentado em North American Cystic Fibrosis Conference 2020, 2020.
  12. Ramalho, AS; Vonk, AM; Silva, Iris AL; Botelho, Hugo M; Bor, R; van Mourik, P; Michel, S; et al. "High reproducibility of forskolin-induced swelling of intestinal organoids across three academic laboratories". Trabalho apresentado em 33rd Annual North American Cystic Fibrosis Conference, 2019.
  13. Silva, Iris AL; Ramalho, Sofia; Centeio, Raquel; Dous¿ova´, Tereza; Kunzelmann, Karl; Farinha, Carlos M; Amaral, Margarida D. "Characterization of the Rare S955P-CFTR Mutation and its Response to Modulators in Cellular Models and Patient-Derived Materials.". Trabalho apresentado em 16th ECFS Basic Science Conference 2019, Dubrovnik, Croatia, 27-30 March 2019., 2019.
  14. Quaresma, Margarida C; Pankonien, Ines; Silva, Iris AL; Railean, Violeta; Amaral, Margarida D. "Partial Epithelial to Mesenchymal Transition (EMT) in CF: CF as an Epithelial Differentiation Disorder". Trabalho apresentado em 16th ECFS Basic Science Conference 2019, Dubrovnik, Croatia, 27-30 March 2019., 2019.
  15. Vonk, Annelotte M; Ramalho, Anabela S; Silva, Iris AL; Silva, Iris AL; Botelho, Hugo M; van Mourik, Peter; Michel, S; et al. "High reproducibility of forskolin-induced swelling of organoids across three academic laboratories.". Trabalho apresentado em 16th ECFS Basic Science Conference 2019, Dubrovnik, Croatia, 27-30 March 2019., 2019.
  16. Silva, Iris AL; Ramalho, Sofia; Awatade, Nikhil T; Centeio, Raquel; Farinha, Carlos M; Amaral, Margarida D. "Personalized medicine for cystic fibrosis: functional characterization of rare CFTR mutations and their response to modulators in patient-derived materials and cellular models". Trabalho apresentado em 15th ECFS Basic Science Conference 2018, Loutraki, Greece, 21-24 March 2018., 2018.
  17. Ramalho, Sofia; Silva, Iris AL; Awatade, Nikhil T.; Amaral, Margarida D; Farinha, Carlos M. "Characterization of rare CFTR mutations and their response to modulators.". Trabalho apresentado em 15th ECFS Basic Science Conference 2018, Loutraki, Greece, 21-24 March 2018., 2018.
  18. Awatade, NT; Felício, V; Ramalho, S; Botelho, Hugo M; Silva, Iris AL; de Poel, E; Vonk, AM; et al. "Functional and biochemical assessment of correctors and potentiators on the rare Cystic Fibrosis-causing R560S mutation". Trabalho apresentado em 31st Annual North American Cystic Fibrosis Conference, 2017.
  19. Awatade, Nikhil T; Botelho, Hugo M; Felício, Verónica; Clarke, Luka A; Silva, Iris AL; Marques, Luis; Ramos, Margarida; Amaral, Margarida D. "CFTR modulators enhance function R334W-CFTR both in intestinal organoids and conditionally reprogrammed human nasal epithelial cells". Trabalho apresentado em 14th ECFS Basic Science Conference 2017, Albufeira, Portugal, 29 March – 01 April 2017., 2017.
  20. Xavier, Joana G; Almeida, Bernardo P; Sum, C; Marreiros, Ana; Eldridge, M; Silva, Iris AL; Silva, Joyce J; et al. "PIK3CA mutant allele differential expression (MADE) associates with breast cancer clinical features.". Trabalho apresentado em European Association for Cancer Research 2016, Manchester, UK, 9-12 July 2016., 2016.
  21. Silva, Iris AL; Michou, Laëtitia; Cancela, M. Leonor; Conceição, Natércia. "Functional study of OPTN promoter: new OPTN regulators and effect of genetic variants". Trabalho apresentado em XI Jornadas Portuguesas de Genética 2016, Coimbra, Portugal. 2-3 June 2016., 2016.
  22. Xavier, Joana G; Almeida, Bernardo P; Sum, C; Marreiros, Ana; Eldridge, M; Silva, Iris AL; Silva, Joyce J; et al. "PIK3CA mutant allele differential expression (MADE) associates with breast cancer clinical features". Trabalho apresentado em Cancer Systems Genetics Conference 2016, Heidelberg, Germany, 19-21 May 2016, 2016.
  23. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Comparative analysis of human and zebrafish OPTN: molecular and evolutionary perspectives". Trabalho apresentado em European Calcified Tissue Society Meeting 2016, Rome, Italy, 14-18 May 2016., 2016.
    10.1530/boneabs.5.P257
  24. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "OPTN and CCDC3 share a bidirectional promoter region that is regulated by NFkB". Trabalho apresentado em European Calcified Tissue Society Meeting 2016, Rome, Italy, 14-18 May 2016., 2016.
  25. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Zebrafish as an animal model to study OPTN role in Paget’s disease of bone". Trabalho apresentado em 4th Interdisciplinary Approaches in Fish Skeletal Biology, Tavira, Portugal, 27-30 April 2015, 2015.
  26. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Functional study of Optineurin (OPTN) variants associated with Paget’s disease of bone". Trabalho apresentado em American Society of Bone and Mineral Research Annual Meeting, Houston, United States of America, 12-15 September, 2014, 2014.
  27. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Functional analysis of a promoter polymorphism of Optineurin, a gene associated to Paget’s disease of Bone". Trabalho apresentado em European Calcified Tissue Society Meeting 2014, Prague, Czech Republic, 17-20 May, 2014, 2014.
  28. Silva, Iris AL; Conceição, Natércia; Michou, Laëtitia; Cancela, M. Leonor. "Single Nucleotide Polymorphism identification and functional analysis in PDB6 locus - A target locus for Paget’s disease of Bone". Trabalho apresentado em European Calcified Tissue Society Meeting 2013, Lisbon, Portugal, 18-21 May, 2013, 2013.
  29. Silva, Iris AL; Conceição, Natércia; Cancela, M. Leonor. "Can zebrafish be a valid model to study Paget's Disease of Bone?". Trabalho apresentado em 3rd Interdisciplinary Approaches in Fish Skeletal Biology, Tavira, Portugal, 22-24 April 2013, 2013.
  30. Gandolfo, Ana Patricia; Silva, Iris AL; Conceição, Natércia; Cancela, M. Leonor. "Zebrafish: a good model to study XPG pathologies?". Trabalho apresentado em XXXVII Portuguese Genetics Conference, Lisboa, Portugal, 28 - 30 May, 2012., 2012.
  31. Silva, Iris AL; Leite, Ricardo B; Cancela, M. Leonor; Conceição, Natércia. "TFIIH Is Remarkably Conserved Between Zebrafish And Human". Trabalho apresentado em V Clinical Biochemistry Workshop, Coimbra, Portugal, 27 January, 2012, 2012.
  32. Adrião, Andreia; Conceição, Natércia; Silva, Iris AL; Grazina, Manuela; Cancela, M. Leonor. "Validation of zebrafish as a model to study MEF2C pathologies". Trabalho apresentado em V Clinical Biochemistry Workshop, Coimbra, Portugal, 27 January, 2012, 2012.
  33. Silva, Iris AL; Cancela, M. Leonor; Conceição, Natércia. "xpd mutations in zebrafish: is there a bone phenotype?". Trabalho apresentado em 2nd Interdisciplinary Approaches in Fish Skeletal Biology, Tavira, Portugal, 26-28 April, 2011., 2011.
  34. Silva, Iris AL; Fazenda, Cindy; Conceição, Natércia; Cancela, M. Leonor. "Study of the Xeroderma pigmentosum D (XPD) expression in zebrafish". Trabalho apresentado em XVII National Biochemistry Congress, Porto, Portugal, 15-17 December, 2010., 2010.
Tese / Dissertação
  1. Silva, Iris AL. "PhD thesis - "Genetic and functional analysis of the PDB6 locus in Paget’s disease of bone"". Doutoramento, 2015.
  2. Silva, Iris AL. "Master thesis - "Molecular cloning and analysis of Xeroderma pigmentosum group-D (xpd) in zebrafish"". Mestrado, 2011.
  3. Silva, Iris AL. "Bachelor thesis - "Diagnosis tests in Breast Cancer detection"". Licenciatura, 2009.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/11/30 Oral presentation in national conference - Personalized Medicine for Cystic Fibrosis: Finding Therapies for All Using Patient-Derived 3D Intestinal Organoids 5ª Conferência Anual da redeSAÚDE 2021
redeSAÚDE (Portugal)
2021/11/20 Oral presentation in national conference - Non eligible mutations for Kaftrio: Future perspectives. Semana Europeia da Fibrose Quística 2021
Associação Nacional de Fibrose Quística
2021/11/12 Oral presentation in national conference - Cystic Fibrosis: Towards personalized medicine 37º Congresso Nacional de Pneumologia
Sociedade Portuguesa de Pneumologia (Portugal)
2021/11 Oral presentation in international conference - Characterization of four rare CFTR trafficking mutants and their response to rescue strategies North American Cystic Fibrosis Conference 2021
Cystic Fibrosis Foundation (Estados Unidos)
2021/06/16 Oral presentation in national conference - Talks in BioMed Talks in BioMed
Universidade do Algarve (Portugal)
2021/06/10 Oral presentation in international conference - First results of the HIT-CF ex vivo organoid study show rescue of CFTR with ultra-rare mutations by a novel triple combination of CFTR modulators 44th European Cystic Fibrosis Conference 2021
European Cystic Fibrosis Society
2020/11/26 Oral presentation in national conference - HIT-CF: Personalised Treatment for Cystic Fibrosis Patients BioISI day
BioISI - Biosystems & integrative sciences institute (Portugal)
2020/11/21 Oral presentation in international conference - To where we are heading: the era of high technology for the treatment of Cystic Fibrosis 1st Interdisciplinary Brazilian Simposium on Cystic Fibrosis
Unidos pela Vida (Brasil)
2019/11/30 Oral presentation in national conference - "Alta reprodutibilidade do ensaio de inchamento induzido por forscolina entre três laboratórios europeus". Jornadas Nacionais de Fibrose Quística 2019
Sociedade Portuguesa de Fibrose Quística (Aveiro, Portugal)
2019/11/30 Oral presentation in national conference - Medicina Personalizada na Fibrose Quística: Caracterização Funcional e Teratipagem de Mutações Raras Jornadas Nacionais de Fibrose Quistica
Sociedade Portuguesa de Fibrose Quistica (Aveiro, Portugal)
2019/10/31 Oral presentation in international conference - Partial Epithelial to Mesenchymal Transition (EMT) in CF: CF as an Epithelial Differentiation Disorder 33rd North American Cystic Fibrosis Conference 2019
Cystic Fibrosis Foundation (Nashville, Estados Unidos)
2019/10/31 Oral presentation in international conference - "High reproducibility of forskolin-induced swelling of intestinal organoids across three academic laboratories" North American Cystic Fibrosis Conference
Cystic Fibrosis Foundation (Nashville, Estados Unidos)
2019/09/12 Oral presentation in international meeting - "Organoids for CF diagnosis: Correlations with rectal biopsies" 3rd REAP ECFS Meeting - Biomarkers
European Cystic Fibrosis Society (Lisboa, Portugal)
2019/05/06 Oral presentation in international conference - Electrophysiological Measurements in Rectal Biopsies: a Better Prognosis Biomarker for CF Disease? 42nd European Cystic Fibrosis Conference
European Cystic Fibrosis Society (Liverpool, Reino Unido)
2019/03/27 Oral presentation in international conference - Characterization of the Rare S955P-CFTR Mutation and its Response to Modulators in Cellular Models and Patient-Derived Materials 16th ECFS Basic Science Conference 2019
European Cystic Fibrosis Society (Dubrovnik, Croácia)
2018/06/06 Oral presentation in international conference by invitation - From the bench to bedside: expanding CFTR modulators to rare mutations by response assessment in patients-derived materials and cellular models 41st European Cystic Fibrosis Conference 2018
European Cystic Fibrosis Society (Belgrade, Sérvia)
2018/04/21 Oral presentation in national conference by invitation - Medicina personalizada na Fibrose Quística - Caracterização funcional de mutações raras na CFTR e resposta a moduladores em amostras de doentes e modelos celulares Jornadas Nacionais de Ciências Biomédicas 2018
Curso de Ciências Biomédicas da UAlg (Faro, Portugal)
2018/02/17 Oral presentation in international conference - "Organoides Intestinais" Workshop Fibrose Cística 2018
Unicamp (Campinas, Brasil)
2017/11/18 Oral presentation in national conference - "Previsão de respostas aos novos fármacos em materiais de pacientes" Jornadas Nacionais Fibrose Quística 2017
Vertex (Fátima, Portugal)
2014/11/24 Oral presentation in national meeting - "Functional study of Optineurin variants associated with Paget’s disease of bone." Post-ASBMR Meeting
Centre Hospitalier Universitaire de Laval (Quebec, Canadá)
2013/04/18 Oral presentation in international conference - "Genetic variation in PDB6 locus and Paget’s Disease of Bone" 47th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Albufeira, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2019/01/03 - Atual Personalised Therapies for all: Restoring airway function in CF using Alternative Chloride Channels
Coorientador de Violeta Railean
Biochemistry (Doutoramento)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020/01/01 - 2021/12/31 Identification of Portuguese patients with Cystic Fibrosis by Complete CFTR Gene Mutation Genotyping and Rectal Biopsy Analyses
Coorientador de Cláudia Rodrigues
Universidade de Lisboa Faculdade de Ciências, Portugal
2018/09 - 2019/12 Epithelial Differentiation: From Organoids to Cells in Cystic Fibrosis Patients
Coorientador de André Gomes
Biochemistry (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018/09/01 - 2019/09/01 Research PhD fellowship - HIT-CF Personalised Treatment for Cystic Fibrosis patients with ultra-rare CFTR Mutations (and beyond)
Coorientador de Ricardo Vieira
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2017/09 - 2018/10 Diagnosis, Prognosis and Personalized Treatment of Cystic Fibrosis
Coorientador de Raquel Centeio
Biochemistry (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017/09/01 - 2018/08/01 Research fellowship - HIT-CF Personalised Treatment for Cystic Fibrosis patients with ultra-rare CFTR Mutations (and beyond)
Coorientador de Rita Marques
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2018/04 - 2018/08 Study of ultra-rare mutations in CFTR using patient derived samples
Orientador
Licenciatura em Bioquímica (Iniciação científica)
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2015 - 2015 Paget’s disease of bone
Coorientador de Sara Teixeira
Medicine (Outra)
Universidade do Algarve, Portugal
2015 - 2015 Study of the regulation of the bidirectional promoter shared by OPTN and CCDC3, via NFkB
Coorientador de Patricia Alves
Biochemistry (Licenciatura/Bacharelato)
Universidade do Algarve, Portugal
2015 - 2015 Osteosarcoma in Paget’s disease of bone
Coorientador de Teresa Lourenço
Biomedical Sciences (Licenciatura/Bacharelato)
Universidade do Algarve, Portugal
2015 - 2015 Study of the regulation of the bidirectional promoter shared by OPTN and CCDC3, via NFkB
Coorientador de Ricardo Matos
Biomedical Sciences (Licenciatura/Bacharelato)
Universidade do Algarve, Portugal
2015 - 2015 Contribution of PDB6 locus to Paget’s disease of bone
Coorientador de David Marques
Medicine
Universidade do Algarve, Portugal
2014 - 2014 Study of the putative effect of rs3829923 in OPTN gene on the predisposition to Paget’s disease of bone
Coorientador de Ana André
Biomedical Sciences (Licenciatura/Bacharelato)
Universidade do Algarve, Portugal
2014 - 2014 Study of characteristics and activity of the bidirectional promoter shared by two genes: OPTN and CCDC3
Coorientador de Inês Perrolas
Biomedical Sciences (Licenciatura/Bacharelato)
Universidade do Algarve, Portugal
2013 - 2013 Study of the putative effect of RV-9906 in OPTN gene on the predisposition to Paget’s disease of bone
Coorientador de Biomedical Sciences
Ciências Biomédicas (Licenciatura/Bacharelato)
Universidade do Algarve, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2016/07/01 - 2016/07/02 Organization of the first annual scientific meeting organized by CBMR (2015/07/01)
Congresso (Coorganizador)
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
2015/02 - 2015/02 OPEN DAY - Organization of the activity ‘From the crime scene to the lab’ in the scope of the Open Day of the University of Algarve. Press release: http://www.sulinformacao.pt/2015/02/fotogaleria-ualg-teve-mais-um-dia-aberto-onde-ate-se-resolveram-crimes/ (2015/02)
Outro (Outra)
Universidade do Algarve, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2019/11/08 Transcriptional regulation of the overlapping human genes OPTN and CCDC3
Arguente principal
Michele Loiodice (Mestrado)
Universidade do Algarve, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2018/04/30 - Atual Seminar in Cell Culture Techniques - "Medicina personalizada na Fibrose Quística - Caracterização funcional de mutações raras na CFTR e resposta a moduladores em amostras de doentes e modelos celulares" Ciências Biomédicas (Licenciatura) Universidade do Algarve, Portugal
2016/04/27 - Atual Seminar in Human Genetics - "Paget’s Disease of Bone" Molecular and Microbiotic Biology (Mestrado) Universidade do Algarve, Portugal
2015/05/27 - Atual Seminar in Molecular Genetics - "TFIIH: Da Genética para a Clínica" Ciências Biomédicas/ Ciências Farmacêuticas/ Biologia/ Biologia Marinha (Licenciatura) Universidade do Algarve, Portugal
2014/04/08 - Atual Seminar in Molecular Genetics - "TFIIH: Da Genética para a Clínica" Ciências Biomédicas Universidade do Algarve, Portugal
2014/01/29 - Atual Seminar in Bone and Cartilage biology - "Análise genética do locus PDB6 na Doença Óssea de Paget" Ciências Biomédicas Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2013/12/10 - Atual Seminar in Human Genetics - "Doença Óssea de Paget" Ciências Biomédicas Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
2020/04/09 - 2020/04/09 Seminar in Cell Culture Techniques - "Medicina personalizada na Fibrose Quística - Caracterização funcional de mutações raras na CFTR e resposta a moduladores em amostras de doentes e modelos celulares" Ciências Biomédicas (Licenciatura) Universidade do Algarve, Portugal
2014/02 - 2014/04 Lecturing practical classes of Technology of animal cell culture to students of the Biomedical Sciences degree Ciências Biomédicas (Licenciatura) Universidade do Algarve, Portugal
2013/02 - 2013/03 Lecturing practical classes of Technology of animal cell culture to students of the Biomedical Sciences degree Ciências Biomédicas (Licenciatura) Universidade do Algarve, Portugal

Membro de associação

Nome da associação Tipo de participação
2014/03/14 - Atual Founder of Associação Nacional de Ciências Biomédicas (ANCiB) Founder

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2017 - 2022 Member of the European Cystic Fibrosis Society (ECFS)
Membro
European Cystic Fibrosis Society, Dinamarca
2014 - 2016 Member of the American Society of Bone and Mineral Research
Membro
American Society of Bone and Mineral Research, Estados Unidos
2012 - 2016 Member of the European Calcified Tissue Society (ECTS)
Membro
European Calcified Tissue Society, Reino Unido
2013 - 2015 Biomedical Sciences Doctorate Pedagogic Committee President
Presidente / Vice-presidente
Universidade do Algarve, Portugal
2012 - 2013 Biomedical Sciences Doctorate Pedagogic Committee Vice President
Presidente / Vice-presidente
Universidade do Algarve, Portugal
2009 - 2010 Biomedical Sciences Master Pedagogic Committee Vice President
Presidente / Vice-presidente
Universidade do Algarve, Portugal
Distinções

Prémio

2023 Alumni Career Award
Universidade do Algarve, Portugal
2022 Outstanding Professional Achievement Award
Rotary Club Tavira, Portugal
2021 Best Young Investigator - 43rd European Cystic Fibrosis Society Conference
European Cystic Fibrosis Society, Dinamarca
2019 Cystic Fibrosis Research Bursaries - 42nd European Cystic Fibrosis Society Conference
Chiesi Limited UK, Reino Unido
2018 Student Helper Award - 15th Basic Science Conference
European Cystic Fibrosis Society, Dinamarca
2018 Best Young Investigator - 41st European Cystic Fibrosis Society Conference
European Cystic Fibrosis Society, Dinamarca

Outra distinção

2023 Voto Congratulação
Câmara Municipal de Tavira, Portugal
2011 Merit Scholarship
Universidade do Algarve, Portugal
2010 Merit Scholarship
Universidade do Algarve, Portugal