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Ana Maria Marques Valentim. Graduated in Biology at the University of Coimbra and completed the PhD in Veterinarian Sciences in 2012/03/01 at Porto University, Instituto de Ciências Biomédicas Abel Salazar (ICBAS). Is a contracted researcher at the Instituto de Biologia Molecular e Celular/ Instituto de Investigação e Inovação em Saúde (i3S), integrated into the Laboratory Animal Science group where she has been developing the research line of anaesthesia refinement in animal models, currently zebrafish, in collaboration with the University of Trás-os-Montes e Alto Douro (UTAD). Recently, she is involved in refining other techniques, such as analgesia and environmental enrichment. Is part of the team of trainers of the Laboratory Animal Science course at i3S (the only course accredited by FELASA in Portugal), and participates in external courses. She is involved in a project to create e-learning modules for the Laboratory Animal Science area for the EU Commission as an expert in the recognition of stress and pain and the biology of zebrafish. Published 42 articles in journals and 3 book chapters, and was guest editor in 2 special issues. Organized 7 events. Supervised / co-supervised (or ongoing) 4 PhD theses, 3 MSc dissertations, and 7 works of course completion of LSc/BSc. Has been involved in 10 projects, of which 3 as the Principal Investigator. Her consolidated expertise in zebrafish animal models, specifically in the areas of anaesthesia, behaviour, and laboratory animal science, allows her to make substantial contributions to improving animal welfare and minimizing the impact of confounding factors in research, such as anaesthesia, analgesia, and husbandry conditions. In addition to her focus on animal welfare, Ana Maria is committed to enhancing the zebrafish model for research purposes. For instance, she is involved in developing behavioural assessments to study SCA37 models and other diseases like diabetes using zebrafish.
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Identificação

Identificação pessoal

Nome completo
Ana Maria Marques Valentim

Nomes de citação

  • Valentim, Ana
  • Valentim, Ana M

Identificadores de autor

Ciência ID
9E18-3854-6BA9
ORCID iD
0000-0003-1428-0691
Google Scholar ID
1TyedkUAAAAJ
Researcher Id
C-3389-2013
Scopus Author Id
24339284100

Endereços de correio eletrónico

  • amaria@ibmc.up.pt (Profissional)
  • amaria@i3s.up.pt (Profissional)

Telefones

Telefone
  • 226074900 (Profissional)

Moradas

  • i3S - IBMC. Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Agrárias - Ciências Veterinárias
  • Ciências Médicas e da Saúde - Medicina Básica - Toxicologia
  • Ciências Naturais - Ciências Biológicas - Biologia das Ciências do Comportamento

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português (Idioma materno)
Formação
Grau Classificação
2023/11
Concluído
 Análise e Exploração de Dados em R/ "Analyzing and exploring data in R" (Outros)
Universidade do Porto Faculdade de Ciências, Portugal
2023/10
Concluído
 Course Building and Leading Research Teams (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/06/01 - 2022/06/08
Concluído
 Research Project Management (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/06/20 - 2016/06/23
Concluído
 International Zebrafish and Medaka Course (Outros)
Karlsruher Institut für Technologie, Alemanha
 Approved
2008/02/01 - 2012/03/01
Concluído
 Ciências Veterinárias (Doutoramento)
Especialização em PhD in Veterinary Sciences
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Behavioural effects of anaesthetics in mice-risk of cognitive alterations " (TESE/DISSERTAÇÃO)
 Aproved with distinction
2006/11/20 - 2006/11/24
Concluído
 Post-graduate course of Experimental Design and Statistical Methods in Biomedical Experimentation (Outros)
Itä-Suomen yliopisto, Finlândia
 Approved
2006/06/12 - 2006/06/23
Concluído
 International course in Laboratory Animal Science (Outros)
Universiteit Utrecht, Países Baixos
 Approved
2005
Concluído
 Biology (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Ethological study of a freshwater fish, Cobitis paludica" (TESE/DISSERTAÇÃO)
 17 (0-20)
2000
Concluído
 Cientifico-Natural (Ensino secundário)
Escola Secundária de Tondela, Portugal
"none" (TESE/DISSERTAÇÃO)
 18 (0-20)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/01/02 - Atual Investigador Contratado (Investigação) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2015/04/01 - 2018/12/29 Pós-doutorado (Investigação) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/07/01 - 2015/09/30 Investigador principal convidado (carreira) (Investigação) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2012/04/02 - 2013/06/30 Pós-doutorado (Investigação) Universidade de Trás-os-Montes e Alto Douro, Portugal
2006/02/01 - 2008/01/31 Investigador (Investigação) Universidade de Trás-os-Montes e Alto Douro, Portugal
2005/10/03 - 2006/01/31 Investigador (Investigação) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2004/10/01 - 2005/06/30 Estagiário de Investigação (Investigação) Instituto Superior de Psicologia Aplicada Centro de Investigacao, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/08/21 - 2020/01/17 Maternity leave Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2008/02/01 - 2012/03/01 PhD student (FCT studentship) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Projetos

Bolsa

Designação Financiadores
2024 - 2025 Analgesics absorption and elimination: the path to improve prolonged analgesia in zebrafish
N/A
Investigador responsável
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 American College of Laboratory Animal Medicine
Em curso
2018 - 2022 Pathogenic Mechanisms and Therapy in a Repeat Disease Caused by a Noncoding Mutation in the DAB1 Gene
PTDC/MED-GEN/29255/2017
Investigador
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/06 - 2021/12/26 ZEBREFINE: Refining zebrafish anesthesia: economical, clinical and animal welfare implications
POCI-01-0145-FEDER-029542
Investigador responsável
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Em curso
2015 - 2018 Optimizing anaesthesia for adult zebrafish – a practical and animal welfare-based approach
SFRH/BPD/103006/2014
Bolseiro de Pós-Doutoramento
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/07 - 2015/06 Zebrafish (Danio rerio)anaesthesia and potential implications in research - reduction, replacement and refining techniques/procedures
131642
Provided by PTCRIS: 131642
Investigador responsável
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2010/04 - 2013/09 Effects of Ketamine anaesthesia in animal models used on research
Provided by PTCRIS: 99022
PTDC/CVT/099022/2008
Investigador Pós-doutorado
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2008/02 - 2012/01 BEHAVIOURAL EFFECTS OF ANESTHETICS IN MICE
SFRH/BD/36121/2007
Bolseiro de Doutoramento
Fundação para a Ciência e a Tecnologia
2006/02 - 2008/01 Refinements in laboratory animals anaesthesia, behavioural and physiological measures
Provided by PTCRIS: 59056
Provided by PTCRIS: 59056
Bolseiro de Investigação
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2022/01 - Atual Development of interactive e-learning modules on specific areas of the Education & Training framework facilitating implementation of DIR 2010/63/EU
ENV/2021/OP/0011
Module expert in "Basic and appropriate biology– zebrafish" and "Recognition of pain, suffering and distress – zebrafish"
Universiteit Utrecht, Países Baixos
 European Commission
Em curso
Produções

Publicações

Artigo em conferência
  1. Pereira, A.M.; Antunes, L.; Valentim, A.M.; Correia, R.; Gabriel, J.. "Development of a respiratory rate monitoring device for mice anesthesia induction chamber". 2014.
    10.1109/MeMeA.2014.6860037
Artigo em revista
  1. Jorge, Sara; Félix, Luís; Costas, Benjamín; Valentim, Ana M.. "Advancing cortisol measurements in zebrafish: Analytical validation of a commercial ELISA kit for skin mucus cortisol analysis". MethodsX 12 (2024): 102726. http://dx.doi.org/10.1016/j.mex.2024.102726.
    10.1016/j.mex.2024.102726
  2. Beatriz Custódio; Patrícia Carneiro; Joana Marques; Victoria Leiro; Ana M. Valentim; Mafalda Sousa; Sofia D. Santos; José Bessa; Ana P. Pêgo. "Biological Response Following the Systemic Injection of PEG–PAMAM–Rhodamine Conjugates in Zebrafish". Pharmaceutics (2024): https://doi.org/10.3390/pharmaceutics16050608.
    10.3390/pharmaceutics16050608
  3. Santos, C.; Valentim, A.M.; Félix, L.; Balça-Silva, J.; Pinto, M.L.. "Longitudinal effects of ketamine on cell proliferation and death in the CNS of zebrafish". NeuroToxicology 97 (2023): 78-88. http://dx.doi.org/10.1016/j.neuro.2023.05.008.
    Publicado • 10.1016/j.neuro.2023.05.008
  4. Sara Jorge; Luís Félix; Benjamín Costas; Ana M. Valentim. "Housing Conditions Affect Adult Zebrafish (Danio rerio) Behavior but Not Their Physiological Status". Animals (2023): https://doi.org/10.3390/ani13061120.
    10.3390/ani13061120
  5. Jorge M. Ferreira; Sara Jorge; Luís Félix; Gabriela M. Morello; I. Anna S. Olsson; Ana M. Valentim. "Behavioural Aversion and Cortisol Level Assessment When Adult Zebrafish Are Exposed to Different Anaesthetics". Biology (2022): https://doi.org/10.3390/biology11101433.
    10.3390/biology11101433
  6. Jorge M. Ferreira; Luís Félix; Sara Jorge; Sandra M. Monteiro; I. Anna S. Olsson; Ana M. Valentim. "Anesthesia Overdose Versus Rapid Cooling for Euthanasia of Adult Zebrafish". Zebrafish (2022): https://doi.org/10.1089/zeb.2022.0001.
    10.1089/zeb.2022.0001
  7. Luís Félix; Rita Correia; Rita Sequeira; Cristiana Ribeiro; Sandra Monteiro; Luís Antunes; José Silva; Carlos Venâncio; Ana Valentim. "MS-222 and Propofol Sedation during and after the Simulated Transport of Nile tilapia (Oreochromis niloticus)". Biology (2021): https://doi.org/10.3390/biology10121309.
    10.3390/biology10121309
  8. Valentim, Ana M.; Gaburro, Stefano; Parker, Matthew O.. "Editorial: Post-anesthesia Cognitive Dysfunction: How, When and Why". Frontiers in Behavioral Neuroscience 15 (2021): http://dx.doi.org/10.3389/fnbeh.2021.797483.
    Publicado • 10.3389/fnbeh.2021.797483
  9. Sara Jorge; Jorge M. Ferreira; I. Anna S. Olsson; Ana M. Valentim. "Adult Zebrafish Anesthesia: A Study of Efficacy and Behavioral Recovery of Different Anesthetics". Zebrafish (2021): https://doi.org/10.1089/zeb.2021.0023.
    10.1089/zeb.2021.0023
  10. Félix, Luís M.; Luzio, Ana; Antunes, Luís; Coimbra, Ana M.; Valentim, Ana M.. "Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222". Toxicology and Applied Pharmacology 412 (2021): 115385. http://dx.doi.org/10.1016/j.taap.2020.115385.
    10.1016/j.taap.2020.115385
  11. Félix, L.M.; Luzio, A.; Santos, A.; Antunes, L.M.; Coimbra, A.M.; Valentim, A.M.. "MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos". Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 237 108834 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85087124131&partnerID=MN8TOARS.
    10.1016/j.cbpc.2020.108834
  12. Luís Félix; Ana Maria Coimbra; Ana Maria Valentim; Luís Antunes. "Review on the use of zebrafish embryos to study the effects of anesthetics during early development". Critical Reviews in Toxicology (2019): 1-14. https://doi.org/10.1080/10408444.2019.1617236.
    10.1080/10408444.2019.1617236
  13. Santos, A.; Balça-Silva, J.; Félix, L.; Valentim, A.M.; Pires, M.A.; Gonçalves, C.; Pinto, M.L.. "Effects of ketamine exposure in zebrafish central nervous system proliferation capability". Journal of Comparative Pathology 166 (2019): 121. http://dx.doi.org/10.1016/j.jcpa.2018.10.067.
    10.1016/j.jcpa.2018.10.067
  14. Martins T; Valentim A; Pereira N; Antunes LM. "Anaesthetics and analgesics used in adult fish for research: A review.". Laboratory animals (2018): http://europepmc.org/abstract/med/30514148.
    10.1177/0023677218815199
  15. Luís M. Félix; Ana Luzio; Maria Themudo; Luís Antunes; Manuela Matos; Ana M. Coimbra; Ana M. Valentim. "MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos". Reproductive Toxicology 81 (2018): 122-131. https://doi.org/10.1016/j.reprotox.2018.07.086.
    10.1016/j.reprotox.2018.07.086
  16. Sneddon, Lynne U.; Lopez-Luna, Javier; Wolfenden, David C.C.; Leach, Matthew C.; Valentim, Ana M.; Steenbergen, Peter J.; Bardine, Nabila; et al. "Fish sentience denial: Muddying the waters". Animal Sentience 3 21 (2018): http://dx.doi.org/10.51291/2377-7478.1317.
    10.51291/2377-7478.1317
  17. Sneddon, Lynne U.; Wolfenden, David C.C.; Leach, Matthew C.; Valentim, Ana M.; Steenbergen, Peter J.; Bardine, Nabila; Broom, Donald M.; Brown, Culum. "Ample evidence for fish sentience and pain". Animal Sentience 3 21 (2018): http://dx.doi.org/10.51291/2377-7478.1375.
    10.51291/2377-7478.1375
  18. Félix, L.M.; Vidal, A.M.; Serafim, C.; Valentim, A.M.; Antunes, L.M.; Monteiro, S.M.; Matos, M.; Coimbra, A.M.. "Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos". Chemosphere 201 (2018): 730-739. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043517573&partnerID=MN8TOARS.
    10.1016/j.chemosphere.2018.03.049
  19. Sneddon, Lynne U.; Lopez-Luna, Javier; Wolfenden, David C. C.; Leach, Matthew C.; Valentim, Ana M.; Steenbergen, Peter J.; Bardine, Nabila; et al. "Response to: Responses of larval zebrafish to low pH immersion assay. Comment on Lopez-Luna et al.". Journal of Experimental Biology 220 17 (2017): 3192-3194. http://dx.doi.org/10.1242/jeb.163451.
    10.1242/jeb.163451
  20. Magalhães, A.; Valentim, A.; Venâncio, C.; Pereira, M.; Melo, P.; Summavielle, T.; Antunes, L.. "Ketamine alone or combined with midazolam or dexmedetomidine does not affect anxiety-like behaviours and memory in adult wistar rats". Laboratory Animals 51 2 (2017): 147-159. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018396469&partnerID=MN8TOARS.
    10.1177/0023677216652380
  21. Félix, L.M.; Serafim, C.; Valentim, A.M.; Antunes, L.M.; Matos, M.; Coimbra, A.M.. "Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish". Toxicology Letters 279 (2017): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025172761&partnerID=MN8TOARS.
    10.1016/j.toxlet.2017.07.888
  22. Antunes, L.M.; Coimbra, A.M.; Valentim, A.M.. "Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine". Psychopharmacology 234 4 (2017): 549-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-85001555685&partnerID=MN8TOARS.
    10.1007/s00213-016-4491-7
  23. Félix, L.M.; Serafim, C.; Martins, M.J.; Valentim, A.M.; Antunes, L.M.; Matos, M.; Coimbra, A.M.. "Morphological and behavioral responses of zebrafish after 24 h of ketamine embryonic exposure". Toxicology and Applied Pharmacology 321 (2017): 27-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013752088&partnerID=MN8TOARS.
    10.1016/j.taap.2017.02.013
  24. Guedes, S.R.; Valentim, A.M.; Antunes, L.M.. "Mice aversion to sevoflurane, isoflurane and carbon dioxide using an approach-avoidance task". Applied Animal Behaviour Science 189 (2017): 91-97. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011556791&partnerID=MN8TOARS.
    10.1016/j.applanim.2017.01.012
  25. Köhler, A.; Collymore, C.; Finger-Baier, K.; Geisler, R.; Kaufmann, L.; Pounder, K.C.; Schulte-Merker, S.; et al. "Report of workshop on euthanasia for zebrafish - a matter of welfare and science". Zebrafish 14 6 (2017): 547-551. http://www.scopus.com/inward/record.url?eid=2-s2.0-85036516157&partnerID=MN8TOARS.
    10.1089/zeb.2017.1508
  26. Valentim, A.M.; van Eeden, F.J.; Strähle, U.; Olsson, I.A.S.. "Euthanizing zebrafish legally in Europe: Are the approved methods of euthanizing zebrafish appropriate to research reality and animal welfare?". EMBO Reports 17 12 (2016): 1688-1689. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995451033&partnerID=MN8TOARS.
    10.15252/embr.201643153
  27. Valentim, A.M.; Guedes, S.R.; Pereira, A.M.; Antunes, L.M.. "Euthanasia using gaseous agents in laboratory rodents". Laboratory Animals 50 4 (2016): 241-253. http://www.scopus.com/inward/record.url?eid=2-s2.0-84986557845&partnerID=MN8TOARS.
    10.1177/0023677215618618
  28. Félix, L.M.; Serafim, C.; Valentim, A.M.; Antunes, L.M.; Campos, S.; Matos, M.; Coimbra, A.M.. "Embryonic Stage-Dependent Teratogenicity of Ketamine in Zebrafish (Danio rerio)". Chemical Research in Toxicology 29 8 (2016): 1298-1309. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982279770&partnerID=MN8TOARS.
    10.1021/acs.chemrestox.6b00122
  29. Martins, T.; Valentim, A.M.; Pereira, N.; Antunes, L.M.. "Anaesthesia and analgesia in laboratory adult zebrafish: A question of refinement". Laboratory Animals 50 6 (2016): 476-488. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014491998&partnerID=MN8TOARS.
    10.1177/0023677216670686
  30. Valentim, A.M.; Félix, L.M.; Carvalho, L.; Diniz, E.; Antunes, L.M.. "A new anaesthetic protocol for adult zebrafish (Danio rerio): Propofol combined with lidocaine". PLoS ONE 11 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84959205162&partnerID=MN8TOARS.
    10.1371/journal.pone.0147747
  31. Luís M. Félix; Ana M. Vidal; Cindy Serafim; Ana M. Valentim; Luís M. Antunes; Sónia Campos; Manuela Matos; Sandra M. Monteiro; Ana M. Coimbra. "Ketamine-induced oxidative stress at different developmental stages of zebrafish (Danio rerio) embryos". RSC Adv. 6 66 (2016): 61254-61266. http://dx.doi.org/10.1039/c6ra08298j.
    10.1039/c6ra08298j
  32. Santos, Carla; Félix, L.; Neves, M.; Coimbra, A.; Valentim, A.M.; Antunes, L.; Gonçalves, C.; et al. "Refinement Techniques in Zebrafish Anaesthesia – Results from a Pilot Study". Microscopy and Microanalysis 21 S5 (2015): 93-94. http://dx.doi.org/10.1017/s1431927615014270.
    10.1017/s1431927615014270
  33. Ribeiro, P.O.; Rodrigues, P.C.; Valentim, A.M.; Antunes, L.M.. "A single intraperitoneal injection of ketamine does not affect spatial working, reference memory or neurodegeneration in adult mice: An animal study". European Journal of Anaesthesiology 30 10 (2013): 618-626. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884480706&partnerID=MN8TOARS.
    10.1097/EJA.0b013e3283610321
  34. Valentim, A.M.; Ribeiro, P.O.; Olsson, I.A.S.; Antunes, L.M.. "The memory stages of a spatial Y-maze task are not affected by a low dose of ketamine/midazolam". European Journal of Pharmacology 712 1-3 (2013): 39-47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878219774&partnerID=MN8TOARS.
    10.1016/j.ejphar.2013.04.027
  35. Valentim, A.M.; Olsson, I.A.S.; Antunes, L.M.. "The anaesthetic combination of ketamine/midazolam does not alter the acquisition of spatial and motor tasks in adult mice". Laboratory Animals 47 1 (2013): 19-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878042050&partnerID=MN8TOARS.
    10.1258/la.2012.011179
  36. Ribeiro, P.O.; Valentim, A.M.; Rodrigues, P.; Olsson, I.A.; Antunes, L.M.. "Apoptotic neurodegeneration and spatial memory are not affected by sedative and anaesthetics doses of ketamine/medetomidine combinations in adult mice". British Journal of Anaesthesia 108 5 (2012): 807-814. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859840810&partnerID=MN8TOARS.
    10.1093/bja/aes003
  37. Valentim, A.M.; Summavielle, T.; Antunes, L.M.. "Importance of body temperature and clinical data in behavioral and anesthesia studies". Anesthesiology 116 1 (2012): 226-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-84555218001&partnerID=MN8TOARS.
    10.1097/ALN.0b013e31823cf056
  38. Valentim, A.M.; Di Giminiani, P.; Ribeiro, P.O.; Rodrigues, P.; Olsson, I.A.S.; Antunes, L.M.. "Lower isoflurane concentration affects spatial learning and neurodegeneration in adult mice compared with higher concentrations". Anesthesiology 113 5 (2010): 1099-1108. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049352411&partnerID=MN8TOARS.
    10.1097/ALN.0b013e3181f79c7c
  39. Alves, H.C.; Valentim, A.M.; Olsson, I.A.S.; Antunes, L.M.. "Intraperitoneal anaesthesia with propofol, medetomidine and fentanyl in mice". Laboratory Animals 43 1 (2009): 27-33. http://www.scopus.com/inward/record.url?eid=2-s2.0-58349101546&partnerID=MN8TOARS.
    10.1258/la.2008.007036
  40. Valentim, A.M.; Alves, H.C.; Olsson, I.A.S.; Antunes, L.M.. "The effects of depth of isoflurane anesthesia on the performance of mice in a simple spatial learning task". Journal of the American Association for Laboratory Animal Science 47 3 (2008): 16-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649149078&partnerID=MN8TOARS.
  41. Valentim, A.M.; Alves, H.C.; Silva, A.M.; Olsson, I.A.S.; Antunes, L.M.. "Effects of depth of isoflurane anaesthesia on a cognition task in mice". British Journal of Anaesthesia 101 3 (2008): 434-435. http://www.scopus.com/inward/record.url?eid=2-s2.0-50949121694&partnerID=MN8TOARS.
    10.1093/bja/aen228
  42. Alves, H.C.; Valentim, A.M.; Olsson, I.A.S.; Antunes, L.M.. "Intraperitoneal propofol and propofol fentanyl, sufentanil and remifentanil combinations for mouse anaesthesia". Laboratory Animals 41 3 (2007): 329-336. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547617862&partnerID=MN8TOARS.
    10.1258/002367707781282767
Capítulo de livro
  1. Ana M. Valentim. "Behavioral Profiling of Zebrafish (Danio rerio) Larvae: Activity, Anxiety, Avoidance, and Startle Response". 2024.
    10.1007/978-1-0716-3625-1_26
  2. Köhler, Almut; Valentim, Ana M.. "Analgesia, anesthesia, and euthanasia in zebrafish". In Laboratory Fish in Biomedical Research, 119-137. Elsevier, 2022.
    10.1016/b978-0-12-821099-4.00016-x
  3. Valentim, Ana M.. "Behavioral Profiling of Zebrafish (Danio rerio) Larvae Following Teratogen Exposure". In Teratogenicity Testing, 403-419. Springer New York, 2018.
    10.1007/978-1-4939-7883-0_22
Edição de número de revista
  1. Félix, Luís Manuel Lourenço; Valentim, Ana M; Carlos Venâncio. "Research Topic: Efficacy and effects of aquatic animal anaesthesia". Frontiers in Veterinary Science (2024): https://www.frontiersin.org/research-topics/60921/efficacy-and-effects-of-aquatic-animal-anaesthesia.
    Em revisão • Editor convidado
  2. Valentim, Ana M; Sneddon, Lynne; Robyn Crook. "Special Issue "Anaesthetics and Analgesics Used in Aquatic Animals"". Biology (2023): https://www.mdpi.com/journal/biology/special_issues/AAUAA.
    Publicado • Editor convidado
  3. Valentim, Ana M; Gaburro, Stefano; Parker, Matthew O.. "Research Topic Post-anesthesia Cognitive Dysfunction: How, When and Why". Frontiers in Behavioral Neuroscience (2021): https://www.frontiersin.org/research-topics/16916/post-anesthesia-cognitive-dysfunction-how-when-and-why#overview.
    Publicado • Editor convidado
Poster em conferência
  1. Jorge, Sara; Félix, Luís Manuel Lourenço; Costas, Benjamin; Valentim, Ana. "DIVING INTO ZEBRAFISH STRESS: SKIN MUCUS CORTISOL AS A STRESS BIOMARKER". Trabalho apresentado em Aquaculture Europe 2023, 2023.
  2. Santos, C.A.; Félix, Luís Manuel Lourenço; Valentim, Ana M; Antunes, Luis Miguel Joaquim Marques; Pinto, Maria de Lurdes. Autor correspondente: Pinto, Maria de Lurdes. "Effects of ketamine administration in the expression of Sox 2 in zebrafish CNS". Trabalho apresentado em Joint congress of Veterinary Pathology and Veterinary Clinical Pathology, 2023.
  3. Santos, C.; Valentim, Ana M; Félix, Luís; Antunes, Luis Miguel Joaquim Marques; Pinto, Maria de Lurdes. Autor correspondente: Pinto, Maria de Lurdes. "Ketamine administration at the 1-4 somites stage zebrafish does not alter the distribution patterns of serotonin 5-ht-2b receptor in adult animals". Trabalho apresentado em Joint congress of Veterinary Pathology and Veterinary Clinical Pathology, 2023.
  4. Marques, Joana; Teixeira, Joana; Cadete, Francisco; Duque, Marta; Valentim, Ana M; Bessa, Jose.. "Modelling the crosstalk of diabetes and anxiety in zebrafish". Trabalho apresentado em 12th European Zebrafish Meeting, Krakow, Poland, 2023.
  5. Santos, C.; Félix, Luís Manuel Lourenço; Valentim, Ana; Pinto, MLr. "Central nervous system atypical Sox 2 expression following ketamine exposure in zebrafish". Trabalho apresentado em 2ndMeeting of the Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), 2023.
  6. Sara Silva Jorge; Luís Félix; Benjamin Costas Refojos; Valentim, Ana M. "ZMATRIX PROJECT - Changing science and zebrafish welfare one step at a time". Trabalho apresentado em Beyond REMODEL: 3R models for biomedical research, 2023.
  7. Sara Silva Jorge; Ana Claro; Luís Félix; Valentim, Ana M. "The challenge of long duration anaesthesia for zebrafish larvae". Trabalho apresentado em FELASA 2022, 2022.
    10.1177/00236772221103950
  8. Castro, Ana Filipa; Loureiro, Joana R; Valentim, Ana M; Bessa, Jose; Silveira, Isabel. "(AUUUC)n zebrafish developmental model: a tool to study the SCA37 pathogenic mechanism". Trabalho apresentado em 8th McBiology Symposium, 2022.
  9. Jorge, Sara; Valentim, Ana M; et al.. "Protocol for acute stress induction in adult zebrafish - a validation study". Trabalho apresentado em 8th McBiology Symposium, 2022.
  10. Jorge Miguel Custódio Martins Ferreira(C312-4F71-3635); Ingrid Anna Sofia Olsson; Valentim, Ana M. "The importance of behavioural tasks terminology: methodological evidence". Trabalho apresentado em 54th Congress of the ISAE, 2021.
  11. Sara Silva Jorge; Jorge Miguel Custódio Martins Ferreira; Ingrid Anna Sofia Olsson; Valentim, Ana M. "Are anaesthetics affecting zebrafish behaviour? - a post-recovery study". Trabalho apresentado em Zebrafish 2020 virtual meeting, 2020.
  12. Rita Correia; Rita Sequeira; Catarina Ribeiro; Luís Félix; Sandra Mariza Veiga Monteiro; Luis Antunes; Valentim, Ana M; Carlos Venâncio. "Improving fish welfare in transport using MS-222 or propofol as sedative". Trabalho apresentado em AquaImprove: 4th Aquaculture Research Workshop, 2019.
  13. Catarina Ribeiro; Rita Correia; Rita Sequeira; Luís Félix; Luís Antunes; Valentim, Ana M; Carlos Venâncio; Sandra Mariza Veiga Monteiro. "Effect of tricaine mesylate (MS-222) and propofol on Nile Tilapia (Oreochromis niloticus) gill after transport stimulation". Trabalho apresentado em AquaImprove: 4th Aquaculture Research Workshop, 2019.
  14. Rita Sequeira; Rita Correia; Catarina Ribeiro; Carlos Venâncio; Sandra Mariza Veiga Monteiro; Luís Antunes; Valentim, Ana M; Luís Félix. "Oxidative status in the brain and liver of Nile tilapia sedated with propofol and MS-222 under simulated transport conditions". Trabalho apresentado em ”, AquaImprove: 4th Aquaculture Research Workshop, 2019.
  15. Rita Correia; Rita Sequeira; Catarina Ribeiro; Luís Félix; Sandra Mariza Veiga Monteiro; Luís Antunes; Valentim, Ana M; Carlos Venâncio. "Fish welfare: sedative effects of MS222 and propofol under simulated transport conditions". Trabalho apresentado em 11th International Symposium on Wild Fauna, 2019.
  16. Jorge Miguel Custódio Martins Ferreira(C312-4F71-3635); Ingrid Anna Sofia Olsson; Valentim, Ana M. "A less aversive anaesthetic to adult zebrafish". Trabalho apresentado em UFAW International Animal Welfare Science Symposium, 2017.
  17. Valentim, Ana M; et al. "Zebrafish (Danio rerio) aversion to MS222 and propofol/lidocaine anaesthesia". Trabalho apresentado em XIII Congresso Sociedade Portuguesa de Etologia, 2016.
  18. Valentim, Ana M; et al. "Zebrafish as a development model for learning and anxiety alterations induced by ketamine". Trabalho apresentado em International FishMed Conference on Zebrafish Research, 2016.
  19. Valentim, Ana M; et al. "Ketamine long-term effects on learning and anxiety of zebrafish.". Trabalho apresentado em AAALAC International, ESLAV and ECLAM Conference, 2015.
  20. Valentim, Ana M; et al. "Mice aversion to the gases isoflurane, sevoflurane and CO2". Trabalho apresentado em 54th CALAS/ACSAL Symposium, 2015.
  21. Valentim, Ana M; et al. "Automatic detection of righting reflex loss in laboratory rodents with piezoelectric sensors". Trabalho apresentado em 54th CALAS/ACSAL Symposium, 2015.
  22. Valentim, Ana M; et al. "Assessment of central nervous cell proliferation ability in Zebrafish embryos treated with ketamine". Trabalho apresentado em Biomarcadores em Ciência Animal e Ciências Veterinárias: Uma abordagem Interdisciplinar, 2015.
  23. Valentim, Ana M; et al. "A pilot study about alternatives for adult zebrafish anesthesia". Trabalho apresentado em Joint HSBLAS/ESLAV/ECLAM Meeting, 2014.
  24. Valentim, Ana M; Olsson, I A S. "Zebrafish model on the upswing - a behavioural review". Trabalho apresentado em X Congresso Nacional de Etologia, 2013.
  25. Valentim, Ana M; et al. "Anaesthesia as a variable or as a refinement". Trabalho apresentado em ASAB/SEB/NC3Rs Symposium, 2012.
  26. Valentim, Ana M; et al. "Is the common used anaesthetic isoflurane interfering with behavioural results?". Trabalho apresentado em II SPCAL meeting, 2012.
  27. Patricia Ribeiro; Valentim, Ana M; et al. "Cognitive and neurodegenerative effects of the medetomidine/ketamine anesthesia combination in adult mice". Trabalho apresentado em SCAND-FELASA Joint Meeting, 2010.
  28. Patricia Ribeiro; Valentim, Ana M; et al. "Histological and behavioural effects of medetomidine/ketamine anaesthesia in mice". Trabalho apresentado em AVA meeting, 2008.
  29. Héber Alves; Valentim, Ana M; et al. "Tiletamine – Zolazepam - Medetomidine - Fentanyl anaesthesia combination in rats". Trabalho apresentado em FELASA-ICLAS Joint Meeting, 2007.
  30. Héber Alves; Valentim, Ana M; et al. "Propofol- Medetomidine and Fentanyl anaesthesia combination in mice". Trabalho apresentado em FELASA-ICLAS Joint Meeting, 2007.
Pré-impressão
  1. Sara Jorge; Luís Félix; Benjamín Costas; Ana M Valentim. "Housing conditions affect adult zebrafish (Danio rerio) behavior but not their physiological status". 2023. https://doi.org/10.1101/2023.02.10.528020.
    10.1101/2023.02.10.528020
  2. Ferreira, Jorge Miguel; Olsson, I. Anna S.; Valentim, Ana Maria. "Disentangling the terminology of the light/ dark and white/ black test in zebrafish". 2023. http://dx.doi.org/10.31219/osf.io/f9hmq.
    10.31219/osf.io/f9hmq
  3. Jorge, Sara; Ferreira, Jorge M; Olsson, I Anna S; Valentim, Ana M. "Adult zebrafish anaesthesia: a study of efficacy and behavioural recovery of different anaesthetics". 2021. http://dx.doi.org/10.1101/2021.02.23.432432.
    10.1101/2021.02.23.432432
  4. Ferreira, Jorge M; Valentim, Ana M. "Lighter compared to deeper isoflurane anaesthesia can affect recognition memory in male C57BL/6 mice". 2019. http://dx.doi.org/10.1101/645051.
    10.1101/645051
  5. Ferreira, Jorge M; Olsson, I Anna S; Valentim, Ana M. "Adult zebrafish euthanasia: efficacy of anaesthesia overdose versus rapid cooling". 2018. http://dx.doi.org/10.7287/peerj.preprints.27432v1.
    10.7287/peerj.preprints.27432v1
Resumo em conferência
  1. Castro, Ana Filipa; Ana Figueiredo; Joana Maria Geraldes da Rocha Loureiro; Valentim, Ana M; Jose Carlos Ribeiro Bessa; Isabel Alexandra Azevedo Silveira. "SCA37 (ATTTC)n cell and animal models as valuable resources for therapeutic screening". Trabalho apresentado em Final Meeting of COST Action 17103 DARTER Delivery of RNA Antisense Therapeutics, Bilbao, 2023.
  2. Ana Filipa Azevedo Castro; Joana Maria Geraldes da Rocha Loureiro; Valentim, Ana M; Jose Carlos Ribeiro Bessa; Isabel Alexandra Azevedo Silveira. "Is the (AUUUC)n insertion RNA enough for motor dysfunction in SCA37? – insights from a zebrafish developmental model". Trabalho apresentado em 9th Molecular and Cell Biology Symposium, 2023.
  3. Ferreira, Jorge; Inês Caetano; Sofia Barros; Pedro Fernandes; Valentim, Ana M. "Validation of a learning task for TU and AB zebrafish strains". Trabalho apresentado em 8th McBiology Symposium, 2022.
  4. Ferreira, Jorge; Collins, Mark; Valentim, Ana M. "Anaesthesia induced memory impairment: the silent variable". Trabalho apresentado em 8th McBiology Symposium, 2022.
  5. Sara Silva Jorge; Jorge Ferreira; Inês Caetano; Valentim, Ana M. "Would social housing of zebrafish (Danio rerio) interfere with the physiological stress response?". Trabalho apresentado em IJUP 2022, 2022.
  6. Ana Filipa Azevedo Castro; Joana Maria Geraldes da Rocha Loureiro; Jorge Miguel Custódio Martins Ferreira; Valentim, Ana M; Jose Carlos Ribeiro Bessa; Isabel Alexandra Azevedo Silveira. "The spinocerebellar ataxia type 37 ATTTC repeat insertion impacts zebrafish CNS development". Trabalho apresentado em Neuroscience 2022, online, 2022.
  7. Loureiro, Joana R; Valentim, Ana M; Mafalda Sousa; Paula Sampaio; Silveira, Isabel. "The need for speed in zebrafish behavioural analysis". Trabalho apresentado em Euro-BioImaging event: Virtual Pub Speed edition, 2021.
  8. Ana Claro; Sara Jorge; Valentim, Ana M. "Behavioural recovery after long-term anaesthesia in zebrafish larvae". Trabalho apresentado em IJUP 2021, 2021.
  9. Joana Silva; Ferreira, Jorge; Valentim, Ana M. "Behind the scenes of behavioural science in zebrafish: setup and validation of a behavioural task". Trabalho apresentado em IJUP, 2020.
  10. Jorge Ferreira; Anna I Olsson; Valentim, Ana M. "Anaesthetic efficacy and aversion: Comparing 2 common zebrafish protocols with a combination of propofol/lidocaine". Trabalho apresentado em 14th FELASA congress 2019, Prague, 2019.
    10.1177/0023677219839199
  11. Ferreira, Jorge; Collins, Mark; Valentim, Ana M. "Refinement of zebrafish anaesthesia – a behavioural and mechanistic approach to study memory alterations". Trabalho apresentado em InCell to ExCell - MCBiology Seminar 6th edition, 2019.
  12. Jorge M Ferreira; Anna I Olsson; Valentim, Ana M. "Efficacy of different methods of euthanasia in adult zebrafish: anaesthesia overdose and rapid cooling". Trabalho apresentado em SPCAL 2018, Braga, 2018.
    10.1177/0023677218789822
  13. Jorge M Ferreira; Anna I Olsson; Valentim, Ana M. "Can different depths of anaesthesia influence recognition memory in mice?". Trabalho apresentado em SECAL/SPCAL meeting 2015 Abstract book, Caceres, 2015.
    Publicado • 10.1177/0023677215609551
  14. Correia, R.; Pereira, AM; Valentim, Ana M; Azevedo, C.; Silva, E.; Gabriel, J; Antunes, LM. "Automatically detect righting reflex loss and respiratory rate during induction of anaesthesia". Trabalho apresentado em SECAL/SPCAL meeting 2015, Caceres, 2015.
    Publicado • 10.1177/0023677215609551
  15. Antunes, LM; Valentim, Ana M; Guedes, SR; Pereira, AM; Silva, E.; Correia, R.; Gabriel, J. "New developments in gas euthanasia". Trabalho apresentado em SECAL/SPECAL meeting 2015, Caceres, 2015.
    10.1177/0023677215609551
  16. Monteiro, MP; Félix, Luís Manuel Lourenço; Valentim, Ana M. "Short and long-term effects of ketamine exposure in the development of the animal model zebrafish - first outcomes". Trabalho apresentado em Euroanaesthesia 2015, Berlim, 2015.
  17. Valentim, Ana M; Magalhães, Ana; Pereira, M.; Venâncio, C.; Summavielle, Teresa; Antunes, LM. "Is ketamine alone and in combination with midazolam or dexmedetomidine safe regarding post-anaesthetic memory?". Trabalho apresentado em Euroanaesthesia 2013, Barcelona, 2013.
  18. Magalhães, Ana; Valentim, Ana M; Pereira, M.; Melo, P; Venâncio, C.; Summavielle, Teresa; Antunes, LM. "Is ketamine alone or combined with midazolam or dexmedetomidine a good anaesthetic to use in biomedical research that requires behavioural evaluation?". Trabalho apresentado em 12th FELASA SECAL Congress, Barcelona, 2013.
    Publicado
  19. Valentim, Ana M; Anna I Olsson; Antunes, LM. "Influence of anesthetic ketamine/midazolam combination in spatial and motor learning". Trabalho apresentado em Anesthesiology annual meeting 2011, Chicago, 2011.
  20. Ribeiro, PO; Valentim, Ana M; Rodrigues, PC; Antunes, LM. "Different Concentrations of Ketamine did not Affect Cognition or Neurodegeneration in Adult Mice". Trabalho apresentado em Anesthesiology annual meeting 2011, Chicago, 2011.
  21. Valentim, Ana M; Anna I Olsson; Antunes, LM. "Ketamine/Midazolam Do Not Interfere with Consolidation and Recall of a Spatial Task in Mice". Trabalho apresentado em Anesthesiology annual meeting 2010, San Diego, 2010.
  22. Ribeiro, PO; Valentim, Ana M; Rodrigues, PC; Antunes, LM. "Cognitive and Neurodegenerative Effects of the Medetomidine/Ketamine Anesthesia Combination in Mice". Trabalho apresentado em Anesthesiology annual meeting 2010, San Diego, 2010.
  23. Valentim, Ana M; Di Giminiani, P.; Ribeiro, PO; Anna I Olsson; Antunes, LM. "Depth of Anesthesia Effects on Cognition – a Battery of Behavioral Tests". Trabalho apresentado em Anesthesiology Annual meeting 2008, Orlando, 2008.
  24. Valentim, Ana M; Alves, HC; Anna I Olsson; Antunes, LM. "Effects of Depth of Isoflurane Anesthesia on Spatial Cognition of Mice". Trabalho apresentado em Anesthesiology annual meeting 2007, San Francisco, 2007.
  25. Alves, HC; Valentim, Ana M; Anna I Olsson; Antunes, LM. "Effects of medetomidine and fentanyl on propofol requirements for loss of consciousness in mice". Trabalho apresentado em Anesthesiology annual meeting 2007, San Francisco, 2007.
  26. Valentim, Ana M; Alves, HC; Anna I Olsson; Antunes, LM. "Lower isoflurane concentrations may have a stronger effect than higher concentrations in spatial learning in mice". Trabalho apresentado em Euroanaesthesiology 2007, Munich, 2007.
  27. Alves, HC; Valentim, Ana M; Anna I Olsson; Antunes, LM. "Effects of propofol combined with fentanyl, sulfentanil or remifentanil in mice ananesthesia by intraperitoneal route". Trabalho apresentado em Euroanaesthesia 2006, Madrid, 2007.
  28. Alves, HC; Valentim, Ana M; Alves, M.; Anna I Olsson; Antunes, LM. "Synergic effects between alpha2 agonist (medetomidine) and fentanyl with dissociative (tiletamine) and zolazepam in rats anaesthesia". Trabalho apresentado em Euroanaesthesia 2007, Madrid, 2007.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/01 Navigating into the 2R’s of zebrafish research: refinement and reduction examples V SPCAL congress
Sociedade Portuguesa de Animais de Laboratório (Coimbra, Portugal)
2023/12/13 Zebrafish Anaesthesia: A Tail of Refinement and Side-Effects Pain and Analgesia in Zebrafish and Rodent Models
Bioresearch & Veterinary Services, University of Edinburgh (Edinburgh )
2023/11/28 Analgesia in fish - situation point SGV's (Swiss Laboratory Animal Science Association) annual meeting
Swiss Laboratory Animal Science Association (Zurich, Suiça)
2023/04 3Rs and Zebrafish: a swim through our work as laboratory animal scientists Beyond REMODEL: 3R models for biomedical research
i3S – Instituto de Investigação e Inovação em Saúde in Porto, Portugal (Portugal)
2022/06 Anaesthesia induced memory impairment: the silent variable FELASA 2022
(França)
2022/05 ZEBREFINE - a Portuguese project to refine zebrafish anaesthesia Spain and Portugal animal welfare, model refinement and advocacy webinar: technology and science
Spanish National Research Council (online)
2022/02/23 Swimming towards better anaesthetic protocols in zebrafish Focus on zebrafish - practical refinements for fish in research and testing
Royal Society for the Prevention of Cruelty to Animals (RSPCA ) (online, Reino Unido)
2022/01/27 Which anaesthetics can be used for long-duration anaesthesia in zebrafish larvae, and Anaesthetic overdose vs rapid cooling to euthanise adult zebrafish ZEBREFINE - refinement opportunities for zebrafish anaesthesia
i3S – Instituto de Investigação e Inovação em Saúde in Porto, Portugal (online)
2022 Taking the stress out of zebrafish Zebrafish Husbandry Association Euro meeting
The Francis Crick Institute (London, Reino Unido)
2022 A 3D-printed Do It Yourself approach to memory assessment for adult zebrafish Zebrafish Husbandry Association Euro meeting
The Francis Crick Institute (London, Reino Unido)
2021/11 "Efeitos toxicológicos da anestesia em peixe-zebra" - webinar
2021 Long duration anaesthesia in zebrafish larvae XVIII Conference of the Portuguese Society of Ethology- SPE 2021
(online)
2021 Open-source behavioural apparatus for memory assessment for the AB and TU zebrafish strain XVIII Conference of the Portuguese Society of Ethology- SPE 2021
Luso-brasilian organization (online)
2020/11/27 "Efeitos toxicológicos da anestesia em peixe-zebra" - webinar
Escola Universitária Vasco da Gama (online, Portugal)
2018/11 Protocols' comparison to zebrafish anaesthesia and euthanasia Nordic Zebrafish and Husbandry meeting 2018
Karolinska Institute (Stockholm, Suécia)
2017/08 Avaliação de doenças nos roedores Limites críticos e eutanásia IV Symposium of "Bioterismo do Einstein"
Instituto Einstein (São Paulo, Brasil)
2016/04 Anaesthesia of laboratory animals: considering refinement and research I Jornadas do Programa de Doutoramento em Ciências Veterinárias
ICBAS, University of Porto (Porto, Portugal)
2016/02 Zebrafish: an upswing model in research and the need for refinement of anaesthesia International Laboratory Animal Science (LAS) virtual conference
Labroots
2015/10 Optimization of the object recognition task protocol in C57BL/6 mice XII Congresso Sociedade Portuguesa de Etologia
ISPA (Lisbon, Portugal)
2015/06 New developments in gas euthanasia . 54th CALAS/ACSAL Symposium
(Montréal, Canadá)
2014/09 New anaesthesia protocols in zebrafish - pilot study 52nd Annual Meeting GV-SOLAS
(Frankfurt, Alemanha)
2014/04 Session "A Ciência em Portugal" (The Science in Portugal) I Jornadas de Bioquímica
University of Porto (Porto, Portugal)
2012/11 Potential Artifacts Induced by Anesthesia in Rodent Models, Special Topic Lecture 63rd AALAS National Meeting
(Minneapolis, Estados Unidos)
2010/06 No effect of ketamine/midazolam anaesthesia in mice on consolidation or recall of a spatial task SCAND-FELASA Joint Meeting
(Helsinki, Finlândia)
2006/06 "Aspectos etológicos e de bem-estar animal em testes de memória e aprendizagem aplicados a roedores" (Discussion of some topics from learning and memory behavioural tests in rodents) Congresso Nacional de Etologia
Universidade de Coimbra (Coimbra, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023 - Atual Antisense repeat expression in spinocerebellar ataxia type 37 with implications for therapy
Coorientador de Ana Filipa Azevedo Castro
 Biologia Molecular e Celular (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/02/01 - Atual Establishment of different matrices to measure cortisol in zebrafish under acute and chronic stressful situations
Orientador de Sara Jorge
 Ciências Veterinárias (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - Atual Modelling the cross-talk of diabetes and emotional disorders comorbidities in zebrafish for improvement of therapeutic strategies and animal welfare
Coorientador de Joana Marques
 Programa Doutoral em Biologia Molecular e Celular (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/01/02 - Atual Refinement of zebrafish anaesthesia – a behavioural and mechanistic approach to study memory alterations
Orientador de Jorge Miguel Ferreira
 Programa Doutoral em Biologia Molecular e Celular (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/11 - 2024/06 Refinement of analgesic protocol in zebrafish
Orientador
 Applied Science (Licenciatura/Bacharelato)
School of Engineering and Applied Science, Rotterdam University of Applied Science, Países Baixos

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/10 - 2022/12 Behavioural and physiological assessment of socially isolated Zebrafish (Danio rerio)
Orientador de Inês Caetano
 Ciências do Mar - Recursos Marinhos (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/02 - 2022/09 Preference test for environmental enrichment of laboratory adult zebrafish
Orientador de Maria Inês Amaral
 Ciências do Meio Aquático (Licenciatura/Bacharelato)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/02/01 - 2021/02/28 Manutenção de um biotério de peixe-zebra e cuidados a ter com os animais
Orientador
 Prática Veterinária Integrada (Outra)
Escola Universitária Vasco da Gama, Portugal
2020/11 - 2021 The influence of anaesthesia on zebrafish (Danio rerio) memory
Orientador
 Biologia (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Ciências, Portugal
2020/11 - 2021 Effects of anaesthesia induction and recovery on zebrafish (Danio rerio) larvae behaviour
Orientador
 Biologia (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Ciências, Portugal
2019/10 - 2020/07 Setting up and validating a behavioural task to test aversive learning in zebrafish
Orientador de Joana Silva
 Biologia (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Ciências, Portugal
2015 - 2016 Anaesthetic aversion in zebrafish
Orientador
 Ecologia, Ambiente e Território (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
2014 - 2015 Potential Implications of Ketamine Anesthesia on Zebrafish Behavior
Coorientador de Margarida Pinto Monteiro
 Psicologia (Mestrado)
Universidade do Minho, Portugal
2014 - 2015 Object recognition task in mice
Orientador de Margarida Pinto Monteiro
 Basic processes in Psychology (Licenciatura/Bacharelato)
Universidade do Minho, Portugal
2013 - 2014 The effects of isoflurane anaesthesia depth on the performance of mice in a non-spatial memory task
Orientador de Jorge Miguel Custódio Martins Ferreira
 Biologia (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Ciências, Portugal
2012 - 2013 "Implicações da cetamina e suas combinações anestésicas nos níveis de ansiedade no rato Wistar" - Implications of ketamine and its anaesthetic combinations on the anxiety levels of the Wistar rats
Coorientador de Mariana Pereira
 Neurofisiologia (Licenciatura/Bacharelato)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2014 - Atual Junior University: outreach activity consisting in a summer school to high school students to contact with how research is done, in particular in the area of laboratory animal science with the focus on animal behaviour. (2016)
Outro (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/11 - 2022/01 ZEBREFINE - refinement opportunities for zebrafish anaesthesia: presentation of the ZEBREFINE project outputs, and invited talks from the scientific community about the challenges of anaesthesia refinement. (https://www.i3s.up.pt/event?v=200) (2022/01/27 - 2022/01/27)
Encontro (Membro da Comissão Organizadora)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/11 - 2021/10 Wellbeing and Mental Health at Work: a thematic cycle of seminars and workshops, aiming to promote wellbeing and mental health in the i3S work context. (2021/03 - 2021/10)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2019 Building and Leading Research Teams (2019/01 - 2019/01)
Oficina (workshop) (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Psicologia e de Ciências da Educação, Portugal
2018 - 2018 Session "Career development- beyond the scientific skills" IN Annual Retreat of i3S (2018 - 2018)
Outro (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017 - 2018 Career development opportunities for researchers and PhD students: effective communication skills and career guidance (2018/01 - 2018/01)
Oficina (workshop) (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017 - 2018 Career development workshop for researchers in the biosciences (2018/12 - 2018/12)
Oficina (workshop) (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2017 Writing your way into the right job - a CV skills workshop (2017/05 - 2017/05)
Oficina (workshop) (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015 - 2016 Careers in science & beyond (2016 - 2016)
Conferência (Coorganizador)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2022 - Atual Collaborated in this outreach activity by visiting high schools and delivering the workshop "Integridade em experimentação animal". (https://cienciaetal.i3s.up.pt/?page_id=2997)
Oficina (workshop)
 Ciência et al - Programa educativo do i3S
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015 - Atual Mostra da UP: to represent the IBMC and now i3S in the outreach activity of the University of Porto to reach the general public and future researchers and to disclose the research done in the institute.
Exposição
 Mostra da UP
Universidade do Porto, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/01/30 - 2024/01/31 Workshop Formação de Formadores LAS/ "Workshop to train the trainer in Laboratory Animal Science
Oficina (workshop)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020 - 2021 Correspondent in the program "Cartas com Ciência" which promotes communication between scientists and students from disadvantaged socioeconomic contexts by exchanging letters. (https://en.cartascomciencia.org/)
Cartas com Ciência, Portugal
2020/02/06 - 2020/02/07 Workshop "Good practices in doctoral supervision" by the Group of Trainers for the Professionalization of the Doctoral Supervision at University Rovira i Virgili
Oficina (workshop)
 Good practices in doctoral supervision
Universidade do Porto, Portugal

Universitat Rovira i Virgili, Espanha
2019/03 - 2019/03 Introduction to data analysis and image processing with MATLAB- 5th Edition
Oficina (workshop)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/10/09 - 2017/10/11 Course in Experimental design and analysis of data for research with animals
Outro
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/03 - 2017/03 Workshop in Anesthesia and Euthanasia of Zebrafish and Medaka
Oficina (workshop)
 Anesthesia and Euthanasia of Zebrafish and Medaka
Karlsruher Institut für Technologie Fakultät für Chemie und Biowissenschaften, Alemanha
2017/03 - 2017/03 Grant Writing and Reviewing workshop
Oficina (workshop)
 AWRN Grant Writing and Reviewing workshop
Animal Welfare Research Network (AWRN), Reino Unido
2016/04 - 2016/04 Workshop: addressing the needs for refinement in laboratory fish
Oficina (workshop)
 Addressing the needs for refinement in laboratory fish
National Centre for the Replacement Refinement and Reduction of Animals in Research, Reino Unido

Centre for Environment Fisheries and Aquaculture Science, Reino Unido
2016 - 2016 Noite Europeia dos Investigadores: outreach activity as a researcher talking about my research to the general public, the impact on society and to stimulate interest in research careers, especially amongst young people.
Outro
 Noite Europeia dos Investigadores
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Bélgica

Universidade do Porto, Portugal
2012/02 - 2012/02 Workshop on Mice and Rat Colony Management
Oficina (workshop)
 Mice and Rat Colony Management
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2010/03 - 2010/03 Memory formation and memory loss
Oficina (workshop)
 Memory formation and memory loss
Universidad Autónoma de Madrid Facultad de Medicina, Espanha
2010/03 - 2010/03 Euron workshop “Drugs and the brain: an update in psychopharmacology”
Oficina (workshop)
 Drugs and the brain: an update in psychopharmacology
Universidade do Minho, Portugal

Universiteit Maastricht, Países Baixos
2009/08/24 - 2009/08/29 2nd CNCR Behavior Course (1.8 credits according to ECTS)
Volksuniversiteit Amsterdam, Países Baixos
2009/02 - 2009/02 Workshop of Scientific Writing to Senior Researcher
Oficina (workshop)
 Workshop of Scientific Writing to Senior Researcher
Universidade do Porto, Portugal
2008/03 - 2008/03 Course Fish in Experimental Research
Oficina (workshop)
 Fish in Experimental Research
Instituto de Medicina Molecular, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/04/11 Chronic Application Of Low Doses Of Ketamine In The Drinking Water Of Mice: Renal Effects And On Behavioural Responses
Arguente principal
 Cláudia Alexandra Soares Rocha (Mestrado)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/12/15 "Efeitos da presença de visitantes do zoo no comportamento de Pinguins de Humboldt (Spheniscus humboldti) em cativeiro no zoo Santo Inácio, Portugal"
Arguente principal
 Ana Sofia Barros Ferreira Leite Nunes (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09/14 "Efeito do Enriquecimento no polvo-comum (Octopus vulgaris)"
Arguente principal
 Manuel Maria F. de Q. V. e Pinto (Outro)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/07/31 "Efeito do enriquecimento ambiental no comportamento do Urso Pardo ("Ursus arctos") do Zoo da Maia "
Arguente principal
 Rita Maria Rodrigues Alves Gomes (Outro)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/07/31 "A influência de enriquecimento ambiental no comportamento da tartaruga-nariz-de-porco (Carettochelys insculpta) residente no Zoo da Maia"
Arguente principal
 Mafalda Sofia Azevedo Veloso (Outro)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 Brain Expression of the DAB1 Repeat Region causing Spinocerebellar Ataxia Type 37
Arguente principal
 Catarina Silva Viegas (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2020/10 - Atual 3rd PhDay | Back to the Future i3S – Instituto de Investigação e Inovação em Saúde in Porto, Portugal
2016/02 - 2017/02 6th annual Laboratory Animal Science (LAS) virtual conference Labroots

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2024 - 2024 Project evaluator in the Swiss 3RCC Refinement Review Panel
Avaliador
 Swiss 3R competence center, Suiça

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2022/12 - 2023/01 Invitation to evaluate the analgesia procedures of a project involving zebrafish to be sent to the Swiss authority in charge of animal experimentation (the veterinarian of canton Basel-Stadt) for permission to perform experiments. Friedrich Miescher Institute for Biomedical Research, Suiça

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2017 - Atual Ethological analysis of behaviour Neurobiologia (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2016 - Atual Zebrafish procedures - practical lessons Course in Laboratory Animal Science Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2012 - Atual Ethological analysis of behaviour Neurociências (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2008 - Atual Refinement of experimental procedures, humane endpoints and euthanasia Course in Laboratory Animal Science (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2024/02/23 - 2024/03/01 Training the trainer in Animal Welfare in Aquaculture and Public Aquariums module to the WP of the ERASMUS project: AFISHE- Development of aquaculture and fisheries education for green deal in Armenia and Ukraine: from education to ecology Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/01 - 2022/01 "Métodos Humanos de Occisão" Curso de Ciências de Animais de Laboratório (Outros) Instituto Politécnico de Leiria, Portugal
2016 - 2019 Ethics, 3 R’s and scientific integrity Curso de Ciências de Animais Aquáticos de Laboratório (Cal-Aqua) (Outros) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2016 - 2019 Zebrafish biology, housing and maintenance Laboratory animal science course (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2008 - 2019 Handling / Minor procedures in rodents - practical classes Course in Laboratory Animal Science Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/11 - 2016/11 Comportamento e Bem-estar em animais de laboratório - Behaviour and welfare in laboratory animals (invited lecturer) Medicina Veterinária (Licenciatura) Escola Universitária Vasco da Gama, Portugal
2011 - 2011 Introduction to scientific research (invited teacher) Ciências Veterinárias (Doutoramento) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal

Membro de associação

Nome da associação Tipo de participação
2018 - Atual Zebrafish Husbandry Association: International, US Member
2016 - Atual EuFishBioMed: Eggenstein-Leopoldshafen, DE Member
2008 - Atual Sociedade Portuguesa de Animais de Laboratório (SPCAL) Member

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2024 - Atual Fishes Mdpi
2023 - Atual Communications Biology (2399-3642)
2022 - Atual Veterinary Anaesthesia and Analgesia (1467-2987)
2022 - Atual Toxics (2305-6304)
2022 - Atual Journal of marine science and engineering (2077-1312)
2021 - Atual Journal of Applied Animal Research
2021 - Atual Experimental results
2021 - Atual Heliyon
2021 - Atual Biology
2020 - Atual Aquaculture (0044-8486)
2020 - Atual Pharmacology, Biochemistry and Behavior
2020 - Atual Water
2020 - Atual Aquatic Toxicology
2020 - Atual Biomolecules
2019 - Atual Behavioural Brain Research (0166-4328) (Reviewer) Elsevier
2019 - Atual Environmental Pollution (0269-7491) (Reviewer) Elsevier
2018 - Atual Journal of Visualized Experiments (1940-087X) (Reviewer) MyJoVE Corporation
2018 - Atual Regulatory Toxicology and Pharmacology (1096-0295) (Reviewer) Elsevier
2017 - Atual Zebrafish (1557-8542) (Reviewer) Mary Ann Liebert
2017 - Atual PLoS ONE (1932-6203) (Reviewer) Public Library of Science
2014 - Atual Lab Animal (1548-4475) (Reviewer) Springer Science and Business Media LLC
2013 - Atual Neurobiology of Learning and Memory (1095-9564) (Reviewer) Elsevier
2013 - Atual Journal of the American Association for Laboratory Animal Science (1559-6109) (Reviewer) American Association for Laboratory Animal Science
2013 - Atual Drug and Alcohol Dependence (0376-8716) (Reviewer) Elsevier
2012 - Atual Laboratory Animals (1758-1117) (Reviewer) SAGE Publications
2009 - Atual Physiology & Behavior (0031-9384) (Reviewer) Elsevier

Tutoria

Tópico Nome do aluno
2022/01 - Atual Part of the UFAW Mentoring Scheme, UK
2021 - 2022 Laboratory Animal Science course Inês Caetano
2017 - 2017 Laboratory Animal Science course Gabriela Munhoz Morello
2014 - 2014 Laboratory Animal Science course Jorge Miguel Ferreira
2014 - 2014 Laboratory Animal Science course Margarida Pinto Monteiro
2013 - 2013 Acute administration of ketamine and its anesthetic combinations: influence on anxiety in adult rats. Sofia Leal Santos
2012 - 2012 Laboratory Animal Science course Silvana Guedes
2007 - 2008 Effects of medetomidine/ketamine anaesthesia combination in mice at brain level Patrícia do Céu Ribeiro
Distinções

Prémio

2023 AE2023 (Aquaculture Europe) Best Student poster - co-author and supervisor
European Aquaculture Society, Bélgica
2015 Third best poster in the I Iberian Congress for Laboratory Animal Science
Sociedad Española para las Ciencias del Animal de Laboratorio, Espanha
2010 Travel grant - FLAD C&T Papers 2010 to present oral communications in Conferences in the USA
Fundação Luso-Americana, Portugal

Outra distinção

2015 UFAW Animal Welfare Student Scholarship - supervisor
Universities Federation for Animal Welfare, Reino Unido
2014 Individual Post-doc fellowship grant
Fundação para a Ciência e a Tecnologia, I.P., Portugal
2008 Individual PhD scholarship grant
Fundação para a Ciência e a Tecnologia, I.P., Portugal
2004 Prize for the Best Student of Faculdade de Ciência e Tecnologia de Universidade de Coimbra (2003/2004)
Universidade de Coimbra, Portugal